메뉴 건너뛰기




Volumn 1, Issue 1, 2013, Pages

Plasma cell disorders in HIV-infected patients: Epidemiology and molecular mechanisms

Author keywords

AIDS; Epidemiology; Gammopathy; Hematopoietic stem cell transplantation; HIV; Molecular mechanism; Multiple myeloma; Outcome; Treatment

Indexed keywords

BETA INTERFERON; BORTEZOMIB; CHEMOKINE RECEPTOR CXCR4; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EMTRICITABINE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HISTONE METHYLTRANSFERASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 3; INTERLEUKIN 6; K RAS PROTEIN; LENALIDOMIDE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN BCL 6; SCATTER FACTOR; TENOFOVIR; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNINDEXED DRUG; UVOMORULIN; VASCULOTROPIN; VERY LATE ACTIVATION ANTIGEN 4;

EID: 84891166195     PISSN: None     EISSN: 20507771     Source Type: Journal    
DOI: 10.1186/2050-7771-1-8     Document Type: Review
Times cited : (31)

References (106)
  • 1
    • 34247103057 scopus 로고    scopus 로고
    • Differential improvement in survival among patients with AIDS after the introduction of HAART
    • 10.1080/09540120701235628, 17453593
    • Couzigou C, Semaille C, Le Strat Y, Pinget R, Pillonel J, Lot F, Cazein F, Vittecoq D, Desenclos JC. Differential improvement in survival among patients with AIDS after the introduction of HAART. AIDS Care 2007, 19(4):523-531. 10.1080/09540120701235628, 17453593.
    • (2007) AIDS Care , vol.19 , Issue.4 , pp. 523-531
    • Couzigou, C.1    Semaille, C.2    Le Strat, Y.3    Pinget, R.4    Pillonel, J.5    Lot, F.6    Cazein, F.7    Vittecoq, D.8    Desenclos, J.C.9
  • 2
    • 22244466800 scopus 로고    scopus 로고
    • AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy
    • 10.1634/theoncologist.10-6-412, 15967835
    • Cheung MC, Pantanowitz L, Dezube BJ. AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy. Oncologist 2005, 10(6):412-426. 10.1634/theoncologist.10-6-412, 15967835.
    • (2005) Oncologist , vol.10 , Issue.6 , pp. 412-426
    • Cheung, M.C.1    Pantanowitz, L.2    Dezube, B.J.3
  • 3
    • 3242719433 scopus 로고    scopus 로고
    • Plasma cell disorders in HIV-infected patients: from benign gammopathy to multiple myeloma
    • 377-379
    • Dezube BJ, Aboulafia DM, Pantanowitz L. Plasma cell disorders in HIV-infected patients: from benign gammopathy to multiple myeloma. AIDS Read 2004, 14(7):372-374. 377-379.
    • (2004) AIDS Read , vol.14 , Issue.7 , pp. 372-374
    • Dezube, B.J.1    Aboulafia, D.M.2    Pantanowitz, L.3
  • 4
    • 79955595041 scopus 로고    scopus 로고
    • Epidemiology of multiple myeloma
    • 10.1007/978-3-540-85772-3_2, 21509679
    • Becker N. Epidemiology of multiple myeloma. Recent Results Cancer Res 2011, 183:25-35. 10.1007/978-3-540-85772-3_2, 21509679.
    • (2011) Recent Results Cancer Res , vol.183 , pp. 25-35
    • Becker, N.1
  • 5
    • 33845366743 scopus 로고    scopus 로고
    • Higher prevalence of monoclonal gammopathy of undetermined significance in African Americans than whites-the unknown role of underlying HIV infection
    • 2569800, 17128699
    • Konstantinopoulos PA, Pantanowitz L, Dezube BJ. Higher prevalence of monoclonal gammopathy of undetermined significance in African Americans than whites-the unknown role of underlying HIV infection. J Natl Med Assoc 2006, 98(11):1860-1861. 2569800, 17128699.
    • (2006) J Natl Med Assoc , vol.98 , Issue.11 , pp. 1860-1861
    • Konstantinopoulos, P.A.1    Pantanowitz, L.2    Dezube, B.J.3
  • 6
    • 0031453236 scopus 로고    scopus 로고
    • Paraproteinemia, plasmacytoma, myeloma and HIV infection
    • 10.1038/sj.leu.2400875, 9447834
    • Fiorino AS, Atac B. Paraproteinemia, plasmacytoma, myeloma and HIV infection. Leukemia 1997, 11(12):2150-2156. 10.1038/sj.leu.2400875, 9447834.
    • (1997) Leukemia , vol.11 , Issue.12 , pp. 2150-2156
    • Fiorino, A.S.1    Atac, B.2
  • 7
    • 25844477041 scopus 로고    scopus 로고
    • Multiple myeloma: diagnosis and treatment
    • 10.4065/80.10.1371, 16212152
    • Rajkumar SV, Kyle RA. Multiple myeloma: diagnosis and treatment. Mayo Clin Proc 2005, 80(10):1371-1382. 10.4065/80.10.1371, 16212152.
    • (2005) Mayo Clin Proc , vol.80 , Issue.10 , pp. 1371-1382
    • Rajkumar, S.V.1    Kyle, R.A.2
  • 8
    • 77954610729 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management
    • 10.1038/leu.2010.60, 20410922
    • Kyle RA, Durie BG, Rajkumar SV, Landgren O, Blade J, Merlini G, Kroger N, Einsele H, Vesole DH, Dimopoulos M, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management. Leukemia 2010, 24(6):1121-1127. 10.1038/leu.2010.60, 20410922.
    • (2010) Leukemia , vol.24 , Issue.6 , pp. 1121-1127
    • Kyle, R.A.1    Durie, B.G.2    Rajkumar, S.V.3    Landgren, O.4    Blade, J.5    Merlini, G.6    Kroger, N.7    Einsele, H.8    Vesole, D.H.9    Dimopoulos, M.10
  • 9
    • 0026568269 scopus 로고
    • Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation
    • 10.1172/JCI115621, 442888, 1737846
    • Shirai A, Cosentino M, Leitman-Klinman SF, Klinman DM. Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation. J Clin Invest 1992, 89(2):561-566. 10.1172/JCI115621, 442888, 1737846.
    • (1992) J Clin Invest , vol.89 , Issue.2 , pp. 561-566
    • Shirai, A.1    Cosentino, M.2    Leitman-Klinman, S.F.3    Klinman, D.M.4
  • 10
    • 1542283730 scopus 로고    scopus 로고
    • Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection
    • 10.1182/blood-2003-07-2375, 14604962
    • De Milito A, Nilsson A, Titanji K, Thorstensson R, Reizenstein E, Narita M, Grutzmeier S, Sonnerborg A, Chiodi F. Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection. Blood 2004, 103(6):2180-2186. 10.1182/blood-2003-07-2375, 14604962.
    • (2004) Blood , vol.103 , Issue.6 , pp. 2180-2186
    • De Milito, A.1    Nilsson, A.2    Titanji, K.3    Thorstensson, R.4    Reizenstein, E.5    Narita, M.6    Grutzmeier, S.7    Sonnerborg, A.8    Chiodi, F.9
  • 11
    • 35348865545 scopus 로고    scopus 로고
    • Protein electrophoresis and immunoglobulin analysis in HIV-infected patients
    • 10.1309/QWTQFGA9FXN02YME, 17875511
    • Konstantinopoulos PA, Dezube BJ, Pantanowitz L, Horowitz GL, Beckwith BA. Protein electrophoresis and immunoglobulin analysis in HIV-infected patients. Am J Clin Pathol 2007, 128(4):596-603. 10.1309/QWTQFGA9FXN02YME, 17875511.
    • (2007) Am J Clin Pathol , vol.128 , Issue.4 , pp. 596-603
    • Konstantinopoulos, P.A.1    Dezube, B.J.2    Pantanowitz, L.3    Horowitz, G.L.4    Beckwith, B.A.5
  • 13
    • 0027276146 scopus 로고
    • Prospective follow-up of monoclonal gammopathies in HIV-infected individuals
    • 10.1111/j.1365-2141.1993.tb03038.x, 8101720
    • Lefrere JJ, Debbia M, Lambin P. Prospective follow-up of monoclonal gammopathies in HIV-infected individuals. Br J Haematol 1993, 84(1):151-155. 10.1111/j.1365-2141.1993.tb03038.x, 8101720.
    • (1993) Br J Haematol , vol.84 , Issue.1 , pp. 151-155
    • Lefrere, J.J.1    Debbia, M.2    Lambin, P.3
  • 14
    • 0023823182 scopus 로고
    • Isotypy of serum monoclonal immunoglobulins in human immunodeficiency virus-infected adults
    • 1541791, 3147151
    • Briault S, Courtois-Capella M, Duarte F, Aucouturier P, Preud'Homme JL. Isotypy of serum monoclonal immunoglobulins in human immunodeficiency virus-infected adults. Clin Exp Immunol 1988, 74(2):182-184. 1541791, 3147151.
    • (1988) Clin Exp Immunol , vol.74 , Issue.2 , pp. 182-184
    • Briault, S.1    Courtois-Capella, M.2    Duarte, F.3    Aucouturier, P.4    Preud'Homme, J.L.5
  • 15
    • 33750123206 scopus 로고    scopus 로고
    • HIV-associated monoclonal gammopathy: a retrospective analysis of 25 patients
    • 10.1086/508351, 17029142
    • Amara S, Dezube BJ, Cooley TP, Pantanowitz L, Aboulafia DM. HIV-associated monoclonal gammopathy: a retrospective analysis of 25 patients. Clin Infect Dis 2006, 43(9):1198-1205. 10.1086/508351, 17029142.
    • (2006) Clin Infect Dis , vol.43 , Issue.9 , pp. 1198-1205
    • Amara, S.1    Dezube, B.J.2    Cooley, T.P.3    Pantanowitz, L.4    Aboulafia, D.M.5
  • 16
    • 81955165195 scopus 로고    scopus 로고
    • Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network
    • 10.1038/bjc.2011.450, 3242607, 22045184
    • Smith A, Howell D, Patmore R, Jack A, Roman E. Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network. Br J Cancer 2011, 105(11):1684-1692. 10.1038/bjc.2011.450, 3242607, 22045184.
    • (2011) Br J Cancer , vol.105 , Issue.11 , pp. 1684-1692
    • Smith, A.1    Howell, D.2    Patmore, R.3    Jack, A.4    Roman, E.5
  • 17
    • 0035804852 scopus 로고    scopus 로고
    • Association of cancer with AIDS-related immunosuppression in adults
    • 10.1001/jama.285.13.1736, 11277828
    • Frisch M, Biggar RJ, Engels EA, Goedert JJ. Association of cancer with AIDS-related immunosuppression in adults. JAMA 2001, 285(13):1736-1745. 10.1001/jama.285.13.1736, 11277828.
    • (2001) JAMA , vol.285 , Issue.13 , pp. 1736-1745
    • Frisch, M.1    Biggar, R.J.2    Engels, E.A.3    Goedert, J.J.4
  • 18
    • 0037165879 scopus 로고    scopus 로고
    • Rates of non-AIDS-defining cancers in people with HIV infection before and after AIDS diagnosis
    • 10.1097/00002030-200205240-00009, 12004274
    • Grulich AE, Li Y, McDonald A, Correll PK, Law MG, Kaldor JM. Rates of non-AIDS-defining cancers in people with HIV infection before and after AIDS diagnosis. AIDS 2002, 16(8):1155-1161. 10.1097/00002030-200205240-00009, 12004274.
    • (2002) AIDS , vol.16 , Issue.8 , pp. 1155-1161
    • Grulich, A.E.1    Li, Y.2    McDonald, A.3    Correll, P.K.4    Law, M.G.5    Kaldor, J.M.6
  • 19
    • 33746773667 scopus 로고    scopus 로고
    • Trends in cancer risk among people with AIDS in the United States 1980-2002
    • 10.1097/01.aids.0000238411.75324.59, 16868446
    • Engels EA, Pfeiffer RM, Goedert JJ, Virgo P, McNeel TS, Scoppa SM, Biggar RJ. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 2006, 20(12):1645-1654. 10.1097/01.aids.0000238411.75324.59, 16868446.
    • (2006) AIDS , vol.20 , Issue.12 , pp. 1645-1654
    • Engels, E.A.1    Pfeiffer, R.M.2    Goedert, J.J.3    Virgo, P.4    McNeel, T.S.5    Scoppa, S.M.6    Biggar, R.J.7
  • 21
    • 20144381973 scopus 로고    scopus 로고
    • Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy
    • 10.1093/jnci/dji072, 15770006
    • Clifford GM, Polesel J, Rickenbach M, Dal Maso L, Keiser O, Kofler A, Rapiti E, Levi F, Jundt G, Fisch T, et al. Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy. J Natl Cancer Inst 2005, 97(6):425-432. 10.1093/jnci/dji072, 15770006.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.6 , pp. 425-432
    • Clifford, G.M.1    Polesel, J.2    Rickenbach, M.3    Dal Maso, L.4    Keiser, O.5    Kofler, A.6    Rapiti, E.7    Levi, F.8    Jundt, G.9    Fisch, T.10
  • 22
    • 13244277996 scopus 로고    scopus 로고
    • The risk of cancer in HIV-infected people in southeast England: a cohort study
    • 10.1038/sj.bjc.6602273, 2361741, 15583689
    • Newnham A, Harris J, Evans HS, Evans BG, Moller H. The risk of cancer in HIV-infected people in southeast England: a cohort study. Br J Cancer 2005, 92(1):194-200. 10.1038/sj.bjc.6602273, 2361741, 15583689.
    • (2005) Br J Cancer , vol.92 , Issue.1 , pp. 194-200
    • Newnham, A.1    Harris, J.2    Evans, H.S.3    Evans, B.G.4    Moller, H.5
  • 23
    • 34347323902 scopus 로고    scopus 로고
    • Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis
    • 10.1016/S0140-6736(07)61050-2, 17617273
    • Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 2007, 370(9581):59-67. 10.1016/S0140-6736(07)61050-2, 17617273.
    • (2007) Lancet , vol.370 , Issue.9581 , pp. 59-67
    • Grulich, A.E.1    van Leeuwen, M.T.2    Falster, M.O.3    Vajdic, C.M.4
  • 24
    • 0037320637 scopus 로고    scopus 로고
    • Epidemiology of non-Hodgkin lymphomas and other haemolymphopoietic neoplasms in people with AIDS
    • 10.1016/S1470-2045(03)00983-5, 12573353
    • Dal Maso L, Franceschi S. Epidemiology of non-Hodgkin lymphomas and other haemolymphopoietic neoplasms in people with AIDS. Lancet Oncol 2003, 4(2):110-119. 10.1016/S1470-2045(03)00983-5, 12573353.
    • (2003) Lancet Oncol , vol.4 , Issue.2 , pp. 110-119
    • Dal Maso, L.1    Franceschi, S.2
  • 25
    • 0030979332 scopus 로고    scopus 로고
    • B cell superantigens in HIV-1 infection
    • 10.3109/08830189709116524, 9186785
    • Muller S, Kohler H. B cell superantigens in HIV-1 infection. Int Rev Immunol 1997, 14(4):339-349. 10.3109/08830189709116524, 9186785.
    • (1997) Int Rev Immunol , vol.14 , Issue.4 , pp. 339-349
    • Muller, S.1    Kohler, H.2
  • 26
    • 0015837481 scopus 로고
    • Antibody activity of human myeloma globulins
    • Seligmann M, Brouet JC. Antibody activity of human myeloma globulins. Semin Hematol 1973, 10(2):163-177.
    • (1973) Semin Hematol , vol.10 , Issue.2 , pp. 163-177
    • Seligmann, M.1    Brouet, J.C.2
  • 27
    • 0015225148 scopus 로고
    • Myeloma proteins (M-components) with antibody-like activity
    • 10.1056/NEJM197104152841507, 4101199
    • Potter M. Myeloma proteins (M-components) with antibody-like activity. N Engl J Med 1971, 284(15):831-838. 10.1056/NEJM197104152841507, 4101199.
    • (1971) N Engl J Med , vol.284 , Issue.15 , pp. 831-838
    • Potter, M.1
  • 28
    • 0023029392 scopus 로고
    • Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis
    • 10.1084/jem.164.6.2049, 2188476, 3491176
    • Pelicci PG, Knowles DM, Arlin ZA, Wieczorek R, Luciw P, Dina D, Basilico C, Dalla-Favera R. Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis. J Exp Med 1986, 164(6):2049-2060. 10.1084/jem.164.6.2049, 2188476, 3491176.
    • (1986) J Exp Med , vol.164 , Issue.6 , pp. 2049-2060
    • Pelicci, P.G.1    Knowles, D.M.2    Arlin, Z.A.3    Wieczorek, R.4    Luciw, P.5    Dina, D.6    Basilico, C.7    Dalla-Favera, R.8
  • 30
    • 0027211999 scopus 로고
    • Brief report: myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient
    • 10.1056/NEJM199306243282505, 8502271
    • Konrad RJ, Kricka LJ, Goodman DB, Goldman J, Silberstein LE. Brief report: myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient. N Engl J Med 1993, 328(25):1817-1819. 10.1056/NEJM199306243282505, 8502271.
    • (1993) N Engl J Med , vol.328 , Issue.25 , pp. 1817-1819
    • Konrad, R.J.1    Kricka, L.J.2    Goodman, D.B.3    Goldman, J.4    Silberstein, L.E.5
  • 32
    • 0023932037 scopus 로고
    • Identification of HIV-specific oligoclonal immunoglobulins in serum of carriers of HIV antibody
    • Papadopoulos NM, Costello R, Ceroni M, Moutsopoulos HM. Identification of HIV-specific oligoclonal immunoglobulins in serum of carriers of HIV antibody. Clin Chem 1988, 34(5):973-975.
    • (1988) Clin Chem , vol.34 , Issue.5 , pp. 973-975
    • Papadopoulos, N.M.1    Costello, R.2    Ceroni, M.3    Moutsopoulos, H.M.4
  • 33
    • 0024469199 scopus 로고
    • The clinical significance of human immunodeficiency virus type 1-associated paraproteins
    • Ng VL, Chen KH, Hwang KM, Khayam-Bashi H, McGrath MS. The clinical significance of human immunodeficiency virus type 1-associated paraproteins. Blood 1989, 74(7):2471-2475.
    • (1989) Blood , vol.74 , Issue.7 , pp. 2471-2475
    • Ng, V.L.1    Chen, K.H.2    Hwang, K.M.3    Khayam-Bashi, H.4    McGrath, M.S.5
  • 36
    • 0033980611 scopus 로고    scopus 로고
    • Occurrence of primary cancers in association with multiple myeloma and Kaposi's sarcoma in the United States, 1973-1995
    • 10.1002/(SICI)1097-0215(20000215)85:4<453::AID-IJC1>3.0.CO;2-L, 10699913
    • Cannon MJ, Flanders WD, Pellett PE. Occurrence of primary cancers in association with multiple myeloma and Kaposi's sarcoma in the United States, 1973-1995. Int J Cancer 2000, 85(4):453-456. 10.1002/(SICI)1097-0215(20000215)85:4<453::AID-IJC1>3.0.CO;2-L, 10699913.
    • (2000) Int J Cancer , vol.85 , Issue.4 , pp. 453-456
    • Cannon, M.J.1    Flanders, W.D.2    Pellett, P.E.3
  • 38
    • 0037037251 scopus 로고    scopus 로고
    • [Human herpesvirus-8 detection in Kaposi's sarcoma, multiple myeloma, and lymphoproliferative syndromes occurring in immunocompetent and immunocompromised patients]
    • Santon Roldan A, De San JS, Gomez Sanz E, Fernandez Munoz R, Herrera P, Bellas Menendez C. [Human herpesvirus-8 detection in Kaposi's sarcoma, multiple myeloma, and lymphoproliferative syndromes occurring in immunocompetent and immunocompromised patients]. Med Clin (Barc) 2002, 119(7):241-244.
    • (2002) Med Clin (Barc) , vol.119 , Issue.7 , pp. 241-244
    • Santon Roldan, A.1    De San, J.S.2    Gomez Sanz, E.3    Fernandez Munoz, R.4    Herrera, P.5    Bellas Menendez, C.6
  • 41
    • 0031465552 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma
    • author reply 1972-1973
    • Cottoni F, Uccini S. Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma. Science 1997, 278(5345):1972. author reply 1972-1973.
    • (1997) Science , vol.278 , Issue.5345 , pp. 1972
    • Cottoni, F.1    Uccini, S.2
  • 43
    • 0025855722 scopus 로고
    • In vitro infection with HIV enables human CD4+ T cell clones to induce noncognate contact-dependent polyclonal B cell activation
    • Macchia D, Parronchi P, Piccinni MP, Simonelli C, Mazzetti M, Ravina A, Milo D, Maggi E, Romagnani S. In vitro infection with HIV enables human CD4+ T cell clones to induce noncognate contact-dependent polyclonal B cell activation. J Immunol 1991, 146(10):3413-3418.
    • (1991) J Immunol , vol.146 , Issue.10 , pp. 3413-3418
    • Macchia, D.1    Parronchi, P.2    Piccinni, M.P.3    Simonelli, C.4    Mazzetti, M.5    Ravina, A.6    Milo, D.7    Maggi, E.8    Romagnani, S.9
  • 44
    • 0036512435 scopus 로고    scopus 로고
    • Multiple myeloma: evolving genetic events and host interactions
    • Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer 2002, 2(3):175-187.
    • (2002) Nat Rev Cancer , vol.2 , Issue.3 , pp. 175-187
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 45
    • 33745182931 scopus 로고    scopus 로고
    • Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
    • 10.1038/ni1357, 16767092
    • Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R. Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol 2006, 7(7):773-782. 10.1038/ni1357, 16767092.
    • (2006) Nat Immunol , vol.7 , Issue.7 , pp. 773-782
    • Klein, U.1    Casola, S.2    Cattoretti, G.3    Shen, Q.4    Lia, M.5    Mo, T.6    Ludwig, T.7    Rajewsky, K.8    Dalla-Favera, R.9
  • 46
    • 80053024575 scopus 로고    scopus 로고
    • Malignant pirates of the immune system
    • 10.1038/ni.2094, 21934679
    • Rui L, Schmitz R, Ceribelli M, Staudt LM. Malignant pirates of the immune system. Nat Immunol 2011, 12(10):933-940. 10.1038/ni.2094, 21934679.
    • (2011) Nat Immunol , vol.12 , Issue.10 , pp. 933-940
    • Rui, L.1    Schmitz, R.2    Ceribelli, M.3    Staudt, L.M.4
  • 47
    • 0038675193 scopus 로고    scopus 로고
    • Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma
    • 10.1034/j.1600-065X.2003.00052.x, 12846810
    • Bergsagel PL, Kuehl WM. Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma. Immunol Rev 2003, 194:96-104. 10.1034/j.1600-065X.2003.00052.x, 12846810.
    • (2003) Immunol Rev , vol.194 , pp. 96-104
    • Bergsagel, P.L.1    Kuehl, W.M.2
  • 48
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma
    • 10.1182/blood-2005-01-0034, 1895118, 15755896
    • Bergsagel PL, Kuehl WM, Zhan F, Sawyer J, Barlogie B, Shaughnessy J. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood 2005, 106(1):296-303. 10.1182/blood-2005-01-0034, 1895118, 15755896.
    • (2005) Blood , vol.106 , Issue.1 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3    Sawyer, J.4    Barlogie, B.5    Shaughnessy, J.6
  • 49
    • 84859171807 scopus 로고    scopus 로고
    • MYC on the path to cancer
    • 10.1016/j.cell.2012.03.003, 22464321
    • Dang CV. MYC on the path to cancer. Cell 2012, 149(1):22-35. 10.1016/j.cell.2012.03.003, 22464321.
    • (2012) Cell , vol.149 , Issue.1 , pp. 22-35
    • Dang, C.V.1
  • 50
    • 75849131117 scopus 로고    scopus 로고
    • The ups and downs of Myc biology
    • 10.1016/j.gde.2009.11.001, 2822095, 19962879
    • Soucek L, Evan GI. The ups and downs of Myc biology. Curr Opin Genet Dev 2010, 20(1):91-95. 10.1016/j.gde.2009.11.001, 2822095, 19962879.
    • (2010) Curr Opin Genet Dev , vol.20 , Issue.1 , pp. 91-95
    • Soucek, L.1    Evan, G.I.2
  • 51
    • 79958095463 scopus 로고    scopus 로고
    • Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
    • 10.1038/leu.2011.53, 3432644, 21468039
    • Chng WJ, Huang GF, Chung TH, Ng SB, Gonzalez-Paz N, Troska-Price T, Mulligan G, Chesi M, Bergsagel PL, Fonseca R. Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma. Leukemia 2011, 25(6):1026-1035. 10.1038/leu.2011.53, 3432644, 21468039.
    • (2011) Leukemia , vol.25 , Issue.6 , pp. 1026-1035
    • Chng, W.J.1    Huang, G.F.2    Chung, T.H.3    Ng, S.B.4    Gonzalez-Paz, N.5    Troska-Price, T.6    Mulligan, G.7    Chesi, M.8    Bergsagel, P.L.9    Fonseca, R.10
  • 52
    • 78650981573 scopus 로고    scopus 로고
    • Pathogenesis of monoclonal gammopathy of undetermined significance and progression to multiple myeloma
    • 10.1053/j.seminhematol.2010.11.003, 3040450, 21232653
    • Zingone A, Kuehl WM. Pathogenesis of monoclonal gammopathy of undetermined significance and progression to multiple myeloma. Semin Hematol 2011, 48(1):4-12. 10.1053/j.seminhematol.2010.11.003, 3040450, 21232653.
    • (2011) Semin Hematol , vol.48 , Issue.1 , pp. 4-12
    • Zingone, A.1    Kuehl, W.M.2
  • 53
    • 84866544780 scopus 로고    scopus 로고
    • MYC addiction: a potential therapeutic target in MM
    • 10.1182/blood-2012-08-445262, 22996653
    • Kuehl WM, Bergsagel PL. MYC addiction: a potential therapeutic target in MM. Blood 2012, 120(12):2351-2352. 10.1182/blood-2012-08-445262, 22996653.
    • (2012) Blood , vol.120 , Issue.12 , pp. 2351-2352
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 54
    • 38549131395 scopus 로고    scopus 로고
    • AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies
    • 10.1016/j.ccr.2008.01.007, 2255064, 18242516
    • Chesi M, Robbiani DF, Sebag M, Chng WJ, Affer M, Tiedemann R, Valdez R, Palmer SE, Haas SS, Stewart AK, et al. AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies. Cancer Cell 2008, 13(2):167-180. 10.1016/j.ccr.2008.01.007, 2255064, 18242516.
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 167-180
    • Chesi, M.1    Robbiani, D.F.2    Sebag, M.3    Chng, W.J.4    Affer, M.5    Tiedemann, R.6    Valdez, R.7    Palmer, S.E.8    Haas, S.S.9    Stewart, A.K.10
  • 55
    • 84866552319 scopus 로고    scopus 로고
    • Addiction to c-MYC in multiple myeloma
    • 10.1182/blood-2011-08-371567, 22806891
    • Holien T, Vatsveen TK, Hella H, Waage A, Sundan A. Addiction to c-MYC in multiple myeloma. Blood 2012, 120(12):2450-2453. 10.1182/blood-2011-08-371567, 22806891.
    • (2012) Blood , vol.120 , Issue.12 , pp. 2450-2453
    • Holien, T.1    Vatsveen, T.K.2    Hella, H.3    Waage, A.4    Sundan, A.5
  • 56
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
    • 10.1038/nrd2781, 2729321, 19116625
    • Baud V, Karin M. Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov 2009, 8(1):33-40. 10.1038/nrd2781, 2729321, 19116625.
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.1 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 57
    • 0035725855 scopus 로고    scopus 로고
    • Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis
    • 10.1046/j.1365-2141.2001.03102.x, 11703322
    • Ni H, Ergin M, Huang Q, Qin JZ, Amin HM, Martinez RL, Saeed S, Barton K, Alkan S. Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis. Br J Haematol 2001, 115(2):279-286. 10.1046/j.1365-2141.2001.03102.x, 11703322.
    • (2001) Br J Haematol , vol.115 , Issue.2 , pp. 279-286
    • Ni, H.1    Ergin, M.2    Huang, Q.3    Qin, J.Z.4    Amin, H.M.5    Martinez, R.L.6    Saeed, S.7    Barton, K.8    Alkan, S.9
  • 58
    • 77951719556 scopus 로고    scopus 로고
    • Classical and/or alternative NF-kappaB pathway activation in multiple myeloma
    • 10.1182/blood-2009-09-243535, 2867265, 20053756
    • Demchenko YN, Glebov OK, Zingone A, Keats JJ, Bergsagel PL, Kuehl WM. Classical and/or alternative NF-kappaB pathway activation in multiple myeloma. Blood 2010, 115(17):3541-3552. 10.1182/blood-2009-09-243535, 2867265, 20053756.
    • (2010) Blood , vol.115 , Issue.17 , pp. 3541-3552
    • Demchenko, Y.N.1    Glebov, O.K.2    Zingone, A.3    Keats, J.J.4    Bergsagel, P.L.5    Kuehl, W.M.6
  • 59
    • 80053192714 scopus 로고    scopus 로고
    • Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors
    • 10.1074/jbc.M111.284216, 3190767, 21816815
    • Dai Y, Chen S, Wang L, Pei XY, Funk VL, Kramer LB, Dent P, Grant S. Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors. J Biol Chem 2011, 286(39):34036-34050. 10.1074/jbc.M111.284216, 3190767, 21816815.
    • (2011) J Biol Chem , vol.286 , Issue.39 , pp. 34036-34050
    • Dai, Y.1    Chen, S.2    Wang, L.3    Pei, X.Y.4    Funk, V.L.5    Kramer, L.B.6    Dent, P.7    Grant, S.8
  • 60
    • 79960745524 scopus 로고    scopus 로고
    • Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines
    • 10.1371/journal.pone.0022641, 3143180, 21799925
    • Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS One 2011, 6(7):e22641. 10.1371/journal.pone.0022641, 3143180, 21799925.
    • (2011) PLoS One , vol.6 , Issue.7
    • Tagoug, I.1    Sauty De Chalon, A.2    Dumontet, C.3
  • 61
    • 79953674746 scopus 로고    scopus 로고
    • The role of toll-like receptor mediated signalling in the pathogenesis of multiple myeloma
    • 10.1016/j.critrevonc.2010.12.001, 21236697
    • Abdi J, Engels F, Garssen J, Redegeld F. The role of toll-like receptor mediated signalling in the pathogenesis of multiple myeloma. Crit Rev Oncol Hematol 2011, 80(2):225-240. 10.1016/j.critrevonc.2010.12.001, 21236697.
    • (2011) Crit Rev Oncol Hematol , vol.80 , Issue.2 , pp. 225-240
    • Abdi, J.1    Engels, F.2    Garssen, J.3    Redegeld, F.4
  • 62
    • 78149361152 scopus 로고    scopus 로고
    • Toll-like receptors: expression and involvement in multiple myeloma
    • 10.1016/j.leukres.2010.06.002, 20594595
    • Chiron D, Jego G, Pellat-Deuceunynck C. Toll-like receptors: expression and involvement in multiple myeloma. Leuk Res 2010, 34(12):1545-1550. 10.1016/j.leukres.2010.06.002, 20594595.
    • (2010) Leuk Res , vol.34 , Issue.12 , pp. 1545-1550
    • Chiron, D.1    Jego, G.2    Pellat-Deuceunynck, C.3
  • 63
    • 77955804238 scopus 로고    scopus 로고
    • Expression and function of toll-like receptors in multiple myeloma patients: toll-like receptor ligands promote multiple myeloma cell growth and survival via activation of nuclear factor-kappaB
    • 10.1111/j.1365-2141.2010.08284.x, 20629663
    • Xu Y, Zhao Y, Huang H, Chen G, Wu X, Wang Y, Chang W, Zhu Z, Feng Y, Wu D. Expression and function of toll-like receptors in multiple myeloma patients: toll-like receptor ligands promote multiple myeloma cell growth and survival via activation of nuclear factor-kappaB. Br J Haematol 2010, 150(5):543-553. 10.1111/j.1365-2141.2010.08284.x, 20629663.
    • (2010) Br J Haematol , vol.150 , Issue.5 , pp. 543-553
    • Xu, Y.1    Zhao, Y.2    Huang, H.3    Chen, G.4    Wu, X.5    Wang, Y.6    Chang, W.7    Zhu, Z.8    Feng, Y.9    Wu, D.10
  • 65
    • 0038269023 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9
    • 10.1074/jbc.M212473200, 12611893
    • Zou W, Amcheslavsky A, Bar-Shavit Z. CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9. J Biol Chem 2003, 278(19):16732-16740. 10.1074/jbc.M212473200, 12611893.
    • (2003) J Biol Chem , vol.278 , Issue.19 , pp. 16732-16740
    • Zou, W.1    Amcheslavsky, A.2    Bar-Shavit, Z.3
  • 66
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • 10.1038/nri1391, 15229469
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004, 4(7):499-511. 10.1038/nri1391, 15229469.
    • (2004) Nat Rev Immunol , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 69
    • 84864561961 scopus 로고    scopus 로고
    • Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides
    • 10.1182/blood-2012-01-405977, 22529291
    • Egan JB, Shi CX, Tembe W, Christoforides A, Kurdoglu A, Sinari S, Middha S, Asmann Y, Schmidt J, Braggio E, et al. Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. Blood 2012, 120(5):1060-1066. 10.1182/blood-2012-01-405977, 22529291.
    • (2012) Blood , vol.120 , Issue.5 , pp. 1060-1066
    • Egan, J.B.1    Shi, C.X.2    Tembe, W.3    Christoforides, A.4    Kurdoglu, A.5    Sinari, S.6    Middha, S.7    Asmann, Y.8    Schmidt, J.9    Braggio, E.10
  • 70
    • 84864544413 scopus 로고    scopus 로고
    • Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma
    • 10.1182/blood-2012-03-412981, 22573403
    • Walker BA, Wardell CP, Melchor L, Hulkki S, Potter NE, Johnson DC, Fenwick K, Kozarewa I, Gonzalez D, Lord CJ, et al. Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma. Blood 2012, 120(5):1077-1086. 10.1182/blood-2012-03-412981, 22573403.
    • (2012) Blood , vol.120 , Issue.5 , pp. 1077-1086
    • Walker, B.A.1    Wardell, C.P.2    Melchor, L.3    Hulkki, S.4    Potter, N.E.5    Johnson, D.C.6    Fenwick, K.7    Kozarewa, I.8    Gonzalez, D.9    Lord, C.J.10
  • 71
    • 84864570434 scopus 로고    scopus 로고
    • Darwinian evolution and tiding clones in multiple myeloma
    • 10.1182/blood-2012-06-430645, 22859708
    • Bahlis NJ. Darwinian evolution and tiding clones in multiple myeloma. Blood 2012, 120(5):927-928. 10.1182/blood-2012-06-430645, 22859708.
    • (2012) Blood , vol.120 , Issue.5 , pp. 927-928
    • Bahlis, N.J.1
  • 72
    • 0036839144 scopus 로고    scopus 로고
    • In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway
    • 10.1182/blood-2002-01-0102, 12384432
    • Chatterjee M, Honemann D, Lentzsch S, Bommert K, Sers C, Herrmann P, Mathas S, Dorken B, Bargou RC. In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway. Blood 2002, 100(9):3311-3318. 10.1182/blood-2002-01-0102, 12384432.
    • (2002) Blood , vol.100 , Issue.9 , pp. 3311-3318
    • Chatterjee, M.1    Honemann, D.2    Lentzsch, S.3    Bommert, K.4    Sers, C.5    Herrmann, P.6    Mathas, S.7    Dorken, B.8    Bargou, R.C.9
  • 74
    • 1542720384 scopus 로고    scopus 로고
    • Cancer and the microenvironment: myeloma-osteoclast interactions as a model
    • 10.1158/0008-5472.CAN-03-1131, 15026338
    • Yaccoby S, Wezeman MJ, Henderson A, Cottler-Fox M, Yi Q, Barlogie B, Epstein J. Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 2004, 64(6):2016-2023. 10.1158/0008-5472.CAN-03-1131, 15026338.
    • (2004) Cancer Res , vol.64 , Issue.6 , pp. 2016-2023
    • Yaccoby, S.1    Wezeman, M.J.2    Henderson, A.3    Cottler-Fox, M.4    Yi, Q.5    Barlogie, B.6    Epstein, J.7
  • 75
    • 35448934091 scopus 로고    scopus 로고
    • Multiple myeloma: charging toward a bright future
    • 10.3322/CA.57.5.301, 17855486
    • Katzel JA, Hari P, Vesole DH. Multiple myeloma: charging toward a bright future. CA Cancer J Clin 2007, 57(5):301-318. 10.3322/CA.57.5.301, 17855486.
    • (2007) CA Cancer J Clin , vol.57 , Issue.5 , pp. 301-318
    • Katzel, J.A.1    Hari, P.2    Vesole, D.H.3
  • 76
    • 84866373814 scopus 로고    scopus 로고
    • Targeting of adhesion molecules as a therapeutic strategy in multiple myeloma
    • 10.2174/156800912802429337, 22671924
    • Neri P, Bahlis NJ. Targeting of adhesion molecules as a therapeutic strategy in multiple myeloma. Curr Cancer Drug Targets 2012, 12(7):776-796. 10.2174/156800912802429337, 22671924.
    • (2012) Curr Cancer Drug Targets , vol.12 , Issue.7 , pp. 776-796
    • Neri, P.1    Bahlis, N.J.2
  • 77
    • 0034700846 scopus 로고    scopus 로고
    • New insights into role of microenvironment in multiple myeloma
    • 10.1016/S0140-6736(00)00019-2, 10675068
    • Tricot G. New insights into role of microenvironment in multiple myeloma. Lancet 2000, 355(9200):248-250. 10.1016/S0140-6736(00)00019-2, 10675068.
    • (2000) Lancet , vol.355 , Issue.9200 , pp. 248-250
    • Tricot, G.1
  • 78
    • 43149089554 scopus 로고    scopus 로고
    • The pathogenesis of the bone disease of multiple myeloma
    • 10.1016/j.bone.2008.01.027, 2474770, 18406675
    • Edwards CM, Zhuang J, Mundy GR. The pathogenesis of the bone disease of multiple myeloma. Bone 2008, 42(6):1007-1013. 10.1016/j.bone.2008.01.027, 2474770, 18406675.
    • (2008) Bone , vol.42 , Issue.6 , pp. 1007-1013
    • Edwards, C.M.1    Zhuang, J.2    Mundy, G.R.3
  • 79
    • 0141994805 scopus 로고    scopus 로고
    • Consequences of interactions between the bone marrow stroma and myeloma
    • 10.1038/sj.thj.6200313, 14502254
    • Epstein J, Yaccoby S. Consequences of interactions between the bone marrow stroma and myeloma. Hematol J 2003, 4(5):310-314. 10.1038/sj.thj.6200313, 14502254.
    • (2003) Hematol J , vol.4 , Issue.5 , pp. 310-314
    • Epstein, J.1    Yaccoby, S.2
  • 80
    • 84862506605 scopus 로고    scopus 로고
    • Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
    • 10.1182/blood-2011-09-380410, 22394600
    • Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood 2012, 119(24):5782-5794. 10.1182/blood-2011-09-380410, 22394600.
    • (2012) Blood , vol.119 , Issue.24 , pp. 5782-5794
    • Azab, A.K.1    Hu, J.2    Quang, P.3    Azab, F.4    Pitsillides, C.5    Awwad, R.6    Thompson, B.7    Maiso, P.8    Sun, J.D.9    Hart, C.P.10
  • 81
    • 66149150580 scopus 로고    scopus 로고
    • CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    • 10.1182/blood-2008-10-186668, 2676090, 19139079
    • Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson AL, et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood 2009, 113(18):4341-4351. 10.1182/blood-2008-10-186668, 2676090, 19139079.
    • (2009) Blood , vol.113 , Issue.18 , pp. 4341-4351
    • Azab, A.K.1    Runnels, J.M.2    Pitsillides, C.3    Moreau, A.S.4    Azab, F.5    Leleu, X.6    Jia, X.7    Wright, R.8    Ospina, B.9    Carlson, A.L.10
  • 82
    • 0034142369 scopus 로고    scopus 로고
    • Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice
    • Pilarski LM, Hipperson G, Seeberger K, Pruski E, Coupland RW, Belch AR. Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice. Blood 2000, 95(3):1056-1065.
    • (2000) Blood , vol.95 , Issue.3 , pp. 1056-1065
    • Pilarski, L.M.1    Hipperson, G.2    Seeberger, K.3    Pruski, E.4    Coupland, R.W.5    Belch, A.R.6
  • 83
    • 38549132452 scopus 로고    scopus 로고
    • Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance
    • 10.1158/0008-5472.CAN-07-3096, 2603142, 18172311
    • Matsui W, Wang Q, Barber JP, Brennan S, Smith BD, Borrello I, McNiece I, Lin L, Ambinder RF, Peacock C, et al. Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer Res 2008, 68(1):190-197. 10.1158/0008-5472.CAN-07-3096, 2603142, 18172311.
    • (2008) Cancer Res , vol.68 , Issue.1 , pp. 190-197
    • Matsui, W.1    Wang, Q.2    Barber, J.P.3    Brennan, S.4    Smith, B.D.5    Borrello, I.6    McNiece, I.7    Lin, L.8    Ambinder, R.F.9    Peacock, C.10
  • 84
    • 45549101709 scopus 로고    scopus 로고
    • Multiple myeloma cancer stem cells
    • 10.1200/JCO.2007.15.8428, 2610256, 18539970
    • Huff CA, Matsui W. Multiple myeloma cancer stem cells. J Clin Oncol 2008, 26(17):2895-2900. 10.1200/JCO.2007.15.8428, 2610256, 18539970.
    • (2008) J Clin Oncol , vol.26 , Issue.17 , pp. 2895-2900
    • Huff, C.A.1    Matsui, W.2
  • 86
    • 0037148921 scopus 로고    scopus 로고
    • A long-term study of prognosis in monoclonal gammopathy of undetermined significance
    • 10.1056/NEJMoa01133202, 11856795
    • Kyle RA, Therneau TM, Rajkumar SV, Offord JR, Larson DR, Plevak MF, Melton LJ. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 2002, 346(8):564-569. 10.1056/NEJMoa01133202, 11856795.
    • (2002) N Engl J Med , vol.346 , Issue.8 , pp. 564-569
    • Kyle, R.A.1    Therneau, T.M.2    Rajkumar, S.V.3    Offord, J.R.4    Larson, D.R.5    Plevak, M.F.6    Melton, L.J.7
  • 87
    • 23044481861 scopus 로고    scopus 로고
    • Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance
    • 10.1182/blood-2005-03-1038, 1895159, 15855274
    • Rajkumar SV, Kyle RA, Therneau TM, Melton LJ, Bradwell AR, Clark RJ, Larson DR, Plevak MF, Dispenzieri A, Katzmann JA. Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance. Blood 2005, 106(3):812-817. 10.1182/blood-2005-03-1038, 1895159, 15855274.
    • (2005) Blood , vol.106 , Issue.3 , pp. 812-817
    • Rajkumar, S.V.1    Kyle, R.A.2    Therneau, T.M.3    Melton, L.J.4    Bradwell, A.R.5    Clark, R.J.6    Larson, D.R.7    Plevak, M.F.8    Dispenzieri, A.9    Katzmann, J.A.10
  • 88
    • 77957964303 scopus 로고    scopus 로고
    • Advances in the diagnosis, classification, risk stratification, and management of monoclonal gammopathy of undetermined significance: implications for recategorizing disease entities in the presence of evolving scientific evidence
    • 10.4065/mcp.2010.0520, 2947967, 20884827
    • Rajkumar SV, Kyle RA, Buadi FK. Advances in the diagnosis, classification, risk stratification, and management of monoclonal gammopathy of undetermined significance: implications for recategorizing disease entities in the presence of evolving scientific evidence. Mayo Clin Proc 2010, 85(10):945-948. 10.4065/mcp.2010.0520, 2947967, 20884827.
    • (2010) Mayo Clin Proc , vol.85 , Issue.10 , pp. 945-948
    • Rajkumar, S.V.1    Kyle, R.A.2    Buadi, F.K.3
  • 90
    • 0031825334 scopus 로고    scopus 로고
    • Multiple myeloma in young patients: clinical presentation and treatment approach
    • Blade J, Kyle RA. Multiple myeloma in young patients: clinical presentation and treatment approach. Leuk Lymphoma 1998, 30(5-6):493-501.
    • (1998) Leuk Lymphoma , vol.30 , Issue.5-6 , pp. 493-501
    • Blade, J.1    Kyle, R.A.2
  • 91
    • 61849139588 scopus 로고    scopus 로고
    • Extramedullary myeloma in an HIV-seropositive subject. Literature review and report of an unusual case
    • 10.1186/1746-160X-5-4, 2649913, 19152712
    • Feller L, White J, Wood NH, Bouckaert M, Lemmer J, Raubenheimer EJ. Extramedullary myeloma in an HIV-seropositive subject. Literature review and report of an unusual case. Head Face Med 2009, 5:4. 10.1186/1746-160X-5-4, 2649913, 19152712.
    • (2009) Head Face Med , vol.5 , pp. 4
    • Feller, L.1    White, J.2    Wood, N.H.3    Bouckaert, M.4    Lemmer, J.5    Raubenheimer, E.J.6
  • 92
    • 0034794437 scopus 로고    scopus 로고
    • Multiple myeloma as the first manifestation of acquired immunodeficiency syndrome: a case report and review of the literature
    • 10.1007/s002770100339, 11669309
    • Pouli A, Lemessiou H, Rontogianni D, Papanastassiou C, Tsakanikas S, Gerassimou A, Stamatelou M. Multiple myeloma as the first manifestation of acquired immunodeficiency syndrome: a case report and review of the literature. Ann Hematol 2001, 80(9):557-560. 10.1007/s002770100339, 11669309.
    • (2001) Ann Hematol , vol.80 , Issue.9 , pp. 557-560
    • Pouli, A.1    Lemessiou, H.2    Rontogianni, D.3    Papanastassiou, C.4    Tsakanikas, S.5    Gerassimou, A.6    Stamatelou, M.7
  • 93
    • 0036788643 scopus 로고    scopus 로고
    • Fine-needle aspiration cytology of a case of HIV-associated anaplastic myeloma
    • 10.1002/dc.10174, 12357499
    • Stewart JM, Krishnamurthy S. Fine-needle aspiration cytology of a case of HIV-associated anaplastic myeloma. Diagn Cytopathol 2002, 27(4):218-222. 10.1002/dc.10174, 12357499.
    • (2002) Diagn Cytopathol , vol.27 , Issue.4 , pp. 218-222
    • Stewart, J.M.1    Krishnamurthy, S.2
  • 94
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group Br J Haematol 2003, 121(5):749-757. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group.
    • (2003) Br J Haematol , vol.121 , Issue.5 , pp. 749-757
  • 95
    • 0032794347 scopus 로고    scopus 로고
    • Beneficial effect of highly active antiretroviral therapy (HAART) in reducing both HIV viral load and monoclonal gammopathy
    • Cauda R, Lucia MB, Marasca G, Rutella S, Petrucci MT, La Verde G, Gastaldi R. Beneficial effect of highly active antiretroviral therapy (HAART) in reducing both HIV viral load and monoclonal gammopathy. Eur J Haematol 1999, 63(2):134-135.
    • (1999) Eur J Haematol , vol.63 , Issue.2 , pp. 134-135
    • Cauda, R.1    Lucia, M.B.2    Marasca, G.3    Rutella, S.4    Petrucci, M.T.5    La Verde, G.6    Gastaldi, R.7
  • 96
    • 0031875614 scopus 로고    scopus 로고
    • HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy
    • 10.1084/jem.188.2.233, 2212446, 9670036
    • Morris L, Binley JM, Clas BA, Bonhoeffer S, Astill TP, Kost R, Hurley A, Cao Y, Markowitz M, Ho DD, et al. HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy. J Exp Med 1998, 188(2):233-245. 10.1084/jem.188.2.233, 2212446, 9670036.
    • (1998) J Exp Med , vol.188 , Issue.2 , pp. 233-245
    • Morris, L.1    Binley, J.M.2    Clas, B.A.3    Bonhoeffer, S.4    Astill, T.P.5    Kost, R.6    Hurley, A.7    Cao, Y.8    Markowitz, M.9    Ho, D.D.10
  • 97
    • 27444436338 scopus 로고    scopus 로고
    • Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis
    • 10.1086/496985, 16206110
    • Sungkanuparph S, Overton ET, Seyfried W, Groger RK, Fraser VJ, Powderly WG. Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis. Clin Infect Dis 2005, 41(9):1326-1332. 10.1086/496985, 16206110.
    • (2005) Clin Infect Dis , vol.41 , Issue.9 , pp. 1326-1332
    • Sungkanuparph, S.1    Overton, E.T.2    Seyfried, W.3    Groger, R.K.4    Fraser, V.J.5    Powderly, W.G.6
  • 99
    • 4444341874 scopus 로고    scopus 로고
    • HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2
    • Ikezoe T, Saito T, Bandobashi K, Yang Y, Koeffler HP, Taguchi H. HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2. Mol Cancer Ther 2004, 3(4):473-479.
    • (2004) Mol Cancer Ther , vol.3 , Issue.4 , pp. 473-479
    • Ikezoe, T.1    Saito, T.2    Bandobashi, K.3    Yang, Y.4    Koeffler, H.P.5    Taguchi, H.6
  • 100
    • 84864886676 scopus 로고    scopus 로고
    • Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells
    • 10.1038/cddis.2012.87, 3406586, 22825471
    • Kawabata S, Gills JJ, Mercado-Matos JR, Lopiccolo J, Wilson W, Hollander MC, Dennis PA. Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells. Cell Death Dis 2012, 3:e353. 10.1038/cddis.2012.87, 3406586, 22825471.
    • (2012) Cell Death Dis , vol.3
    • Kawabata, S.1    Gills, J.J.2    Mercado-Matos, J.R.3    Lopiccolo, J.4    Wilson, W.5    Hollander, M.C.6    Dennis, P.A.7
  • 101
    • 42449114035 scopus 로고    scopus 로고
    • Multiple myeloma
    • 10.1182/blood-2007-10-078022, 2265446, 18332230
    • Kyle RA, Rajkumar SV. Multiple myeloma. Blood 2008, 111(6):2962-2972. 10.1182/blood-2007-10-078022, 2265446, 18332230.
    • (2008) Blood , vol.111 , Issue.6 , pp. 2962-2972
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 102
    • 0042035648 scopus 로고    scopus 로고
    • Thalidomide-based treatment for HIV-associated multiple myeloma: a case report
    • Aboulafia DM. Thalidomide-based treatment for HIV-associated multiple myeloma: a case report. AIDS Read 2003, 13(8):383-389.
    • (2003) AIDS Read , vol.13 , Issue.8 , pp. 383-389
    • Aboulafia, D.M.1
  • 104
    • 84867485182 scopus 로고    scopus 로고
    • Outcomes of patients with multiple myeloma and renal impairment treated with bortezomib, cyclophosphamide, and dexamethasone without plasma exchange
    • 10.1111/ejh.12008, 22971164
    • Costa LJ, Abbas J, Ortiz-Cruz KL, Kang Y, Stuart RK. Outcomes of patients with multiple myeloma and renal impairment treated with bortezomib, cyclophosphamide, and dexamethasone without plasma exchange. Eur J Haematol 2012, 89(5):432-434. 10.1111/ejh.12008, 22971164.
    • (2012) Eur J Haematol , vol.89 , Issue.5 , pp. 432-434
    • Costa, L.J.1    Abbas, J.2    Ortiz-Cruz, K.L.3    Kang, Y.4    Stuart, R.K.5
  • 105
    • 85047697983 scopus 로고    scopus 로고
    • High-dose chemotherapy and autologous CD34-positive blood stem cell transplantation for multiple myeloma in an HIV carrier
    • 10.1038/sj.bmt.1703348, 11859402
    • Kentos A, Vekemans M, Van Vooren JP, Lambermont M, Liesnard C, Feremans W, Farber CM. High-dose chemotherapy and autologous CD34-positive blood stem cell transplantation for multiple myeloma in an HIV carrier. Bone Marrow Transplant 2002, 29(3):273-275. 10.1038/sj.bmt.1703348, 11859402.
    • (2002) Bone Marrow Transplant , vol.29 , Issue.3 , pp. 273-275
    • Kentos, A.1    Vekemans, M.2    Van Vooren, J.P.3    Lambermont, M.4    Liesnard, C.5    Feremans, W.6    Farber, C.M.7
  • 106
    • 33947644169 scopus 로고    scopus 로고
    • CD4+ T lymphocyte counts after autologous transplantation in multiple myeloma: a retrospective study
    • 10.1080/10428190601094347, 17454590
    • Gorschluter M, Glasmacher A, Sarazin S, Hackbarth F, Hoebert E, Orlopp K, Schmidt-Wolf IG, Mey U. CD4+ T lymphocyte counts after autologous transplantation in multiple myeloma: a retrospective study. Leuk Lymphoma 2007, 48(3):506-512. 10.1080/10428190601094347, 17454590.
    • (2007) Leuk Lymphoma , vol.48 , Issue.3 , pp. 506-512
    • Gorschluter, M.1    Glasmacher, A.2    Sarazin, S.3    Hackbarth, F.4    Hoebert, E.5    Orlopp, K.6    Schmidt-Wolf, I.G.7    Mey, U.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.