메뉴 건너뛰기




Volumn 58, Issue , 2014, Pages 62-75

The Anaphase-Promoting Complex (APC) ubiquitin ligase regulates GABA transmission at the C. elegans neuromuscular junction

Author keywords

Anaphase Promoting Complex; GABA; NMJ; Synapse; Ubiquitin ligase

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ANAPHASE PROMOTING COMPLEX; PROTEIN; SYD 2 PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 84890866074     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2013.12.001     Document Type: Article
Times cited : (22)

References (119)
  • 1
    • 84880709049 scopus 로고    scopus 로고
    • Regulation of APC/C-Cdh1 and its function in neuronal survival
    • Almeida A. Regulation of APC/C-Cdh1 and its function in neuronal survival. Mol. Neurobiol. 2012, 46:547-554.
    • (2012) Mol. Neurobiol. , vol.46 , pp. 547-554
    • Almeida, A.1
  • 2
    • 24744467563 scopus 로고    scopus 로고
    • Cdh1/Hct1-APC is essential for the survival of postmitotic neurons
    • Almeida A., et al. Cdh1/Hct1-APC is essential for the survival of postmitotic neurons. J. Neurosci. 2005, 25:8115-8121.
    • (2005) J. Neurosci. , vol.25 , pp. 8115-8121
    • Almeida, A.1
  • 3
    • 78449238301 scopus 로고    scopus 로고
    • Three Drosophila liprins interact to control synapse formation
    • Astigarraga S., et al. Three Drosophila liprins interact to control synapse formation. J. Neurosci. 2010, 30:15358-15368.
    • (2010) J. Neurosci. , vol.30 , pp. 15358-15368
    • Astigarraga, S.1
  • 4
    • 0033169088 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor
    • Bamber B.A., et al. The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J. Neurosci. 1999, 19:5348-5359.
    • (1999) J. Neurosci. , vol.19 , pp. 5348-5359
    • Bamber, B.A.1
  • 5
    • 14844334970 scopus 로고    scopus 로고
    • The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction
    • Bamber B.A., et al. The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction. Br. J. Pharmacol. 2005, 144:502-509.
    • (2005) Br. J. Pharmacol. , vol.144 , pp. 502-509
    • Bamber, B.A.1
  • 6
    • 78650962524 scopus 로고    scopus 로고
    • Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease
    • Bingol B., Sheng M. Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease. Neuron 2011, 69:22-32.
    • (2011) Neuron , vol.69 , pp. 22-32
    • Bingol, B.1    Sheng, M.2
  • 7
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77:71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 8
    • 33646799113 scopus 로고    scopus 로고
    • Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study
    • Brown L.A., et al. Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study. Int. J. Parasitol. 2006, 36:617-624.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 617-624
    • Brown, L.A.1
  • 9
    • 0037014445 scopus 로고    scopus 로고
    • Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans
    • Burbea M., et al. Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans. Neuron 2002, 35:107-120.
    • (2002) Neuron , vol.35 , pp. 107-120
    • Burbea, M.1
  • 10
    • 84856561254 scopus 로고    scopus 로고
    • Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease
    • Chiodi V., et al. Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease. Neurobiol. Dis. 2012, 45:983-991.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 983-991
    • Chiodi, V.1
  • 11
    • 57149117136 scopus 로고    scopus 로고
    • Profiling synaptic proteins identifies regulators of insulin secretion and lifespan
    • Ch'ng Q., et al. Profiling synaptic proteins identifies regulators of insulin secretion and lifespan. PLoS Genet. 2008, 4:e1000283.
    • (2008) PLoS Genet. , vol.4
    • Ch'ng, Q.1
  • 12
    • 0141987860 scopus 로고    scopus 로고
    • The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg
    • Ciechanover A., Brundin P. The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 2003, 40:427-446.
    • (2003) Neuron , vol.40 , pp. 427-446
    • Ciechanover, A.1    Brundin, P.2
  • 13
    • 84858119736 scopus 로고    scopus 로고
    • Cellular functions of the DUBs
    • Clague M.J., et al. Cellular functions of the DUBs. J. Cell Sci. 2012, 125:277-286.
    • (2012) J. Cell Sci. , vol.125 , pp. 277-286
    • Clague, M.J.1
  • 14
    • 34147189527 scopus 로고    scopus 로고
    • Regulation of neuronal cdc20 (p55cdc) expression by the plasticity-related transcription factor zif268
    • Conway A.M., et al. Regulation of neuronal cdc20 (p55cdc) expression by the plasticity-related transcription factor zif268. Synapse 2007, 61:463-468.
    • (2007) Synapse , vol.61 , pp. 463-468
    • Conway, A.M.1
  • 15
    • 33845259344 scopus 로고    scopus 로고
    • SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS
    • Dai Y., et al. SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS. Nat. Neurosci. 2006, 9:1479-1487.
    • (2006) Nat. Neurosci. , vol.9 , pp. 1479-1487
    • Dai, Y.1
  • 16
    • 0036185163 scopus 로고    scopus 로고
    • Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I
    • Davis E.S., et al. Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I. Genetics 2002, 160:805-813.
    • (2002) Genetics , vol.160 , pp. 805-813
    • Davis, E.S.1
  • 17
    • 77953958000 scopus 로고    scopus 로고
    • Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans
    • Davis K.M., et al. Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans. Mol. Cell. Neurosci. 2012, 44:307-317.
    • (2012) Mol. Cell. Neurosci. , vol.44 , pp. 307-317
    • Davis, K.M.1
  • 18
    • 3943055513 scopus 로고    scopus 로고
    • Ubiquitin-dependent regulation of the synapse
    • DiAntonio A., Hicke L. Ubiquitin-dependent regulation of the synapse. Annu. Rev. Neurosci. 2004, 27:223-246.
    • (2004) Annu. Rev. Neurosci. , vol.27 , pp. 223-246
    • DiAntonio, A.1    Hicke, L.2
  • 19
    • 84862776836 scopus 로고    scopus 로고
    • APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
    • Dimova N.V., et al. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat. Cell Biol. 2012, 14:168-176.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 168-176
    • Dimova, N.V.1
  • 20
    • 58149147500 scopus 로고    scopus 로고
    • The role of the ubiquitin proteasome system in synapse remodeling and neurodegenerative diseases
    • Ding M., Shen K. The role of the ubiquitin proteasome system in synapse remodeling and neurodegenerative diseases. Bioessays 2008, 30:1075-1083.
    • (2008) Bioessays , vol.30 , pp. 1075-1083
    • Ding, M.1    Shen, K.2
  • 21
    • 33746627569 scopus 로고    scopus 로고
    • Factors regulating the abundance and localization of synaptobrevin in the plasma membrane
    • Dittman J.S., Kaplan J.M. Factors regulating the abundance and localization of synaptobrevin in the plasma membrane. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:11399-11404.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 11399-11404
    • Dittman, J.S.1    Kaplan, J.M.2
  • 22
    • 0036336404 scopus 로고    scopus 로고
    • The C. elegans even-skipped homologue, vab-7, specifies DB motoneurone identity and axon trajectory
    • Esmaeili B., et al. The C. elegans even-skipped homologue, vab-7, specifies DB motoneurone identity and axon trajectory. Development 2002, 129:853-862.
    • (2002) Development , vol.129 , pp. 853-862
    • Esmaeili, B.1
  • 23
    • 0037083918 scopus 로고    scopus 로고
    • Fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen
    • Fay D.S., et al. fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes Dev. 2002, 16:503-517.
    • (2002) Genes Dev. , vol.16 , pp. 503-517
    • Fay, D.S.1
  • 24
    • 67650470999 scopus 로고    scopus 로고
    • Maturation of active zone assembly by Drosophila Bruchpilot
    • Fouquet W., et al. Maturation of active zone assembly by Drosophila Bruchpilot. J. Cell Biol. 2009, 186:129-145.
    • (2009) J. Cell Biol. , vol.186 , pp. 129-145
    • Fouquet, W.1
  • 25
    • 20444417496 scopus 로고    scopus 로고
    • The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction
    • Francis M.M., et al. The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction. Neuron 2005, 46:581-594.
    • (2005) Neuron , vol.46 , pp. 581-594
    • Francis, M.M.1
  • 26
    • 79251584863 scopus 로고    scopus 로고
    • APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity
    • Fu A.K., et al. APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity. Nat. Neurosci. 2011, 14:181-189.
    • (2011) Nat. Neurosci. , vol.14 , pp. 181-189
    • Fu, A.K.1
  • 27
    • 0034036432 scopus 로고    scopus 로고
    • EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans
    • Furuta T., et al. EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans. Mol. Biol. Cell 2000, 11:1401-1419.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1401-1419
    • Furuta, T.1
  • 28
    • 79952308317 scopus 로고    scopus 로고
    • Action potentials drive body wall muscle contractions in Caenorhabditis elegans
    • Gao S., Zhen M. Action potentials drive body wall muscle contractions in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:2557-2562.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 2557-2562
    • Gao, S.1    Zhen, M.2
  • 29
    • 80052650281 scopus 로고    scopus 로고
    • Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models
    • Gatto C.L., Broadie K. Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models. Front. Synaptic Neurosci. 2010, 2:4.
    • (2010) Front. Synaptic Neurosci. , vol.2 , pp. 4
    • Gatto, C.L.1    Broadie, K.2
  • 30
    • 0034739852 scopus 로고    scopus 로고
    • Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans
    • Golden A., et al. Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans. J. Cell Biol. 2000, 151:1469-1482.
    • (2000) J. Cell Biol. , vol.151 , pp. 1469-1482
    • Golden, A.1
  • 31
    • 84872846053 scopus 로고    scopus 로고
    • The scaffolding protein SYD-2/Liprin-alpha regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neurons
    • Goodwin P.R., Juo P. The scaffolding protein SYD-2/Liprin-alpha regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neurons. PLoS One 2013, 8:e54763.
    • (2013) PLoS One , vol.8
    • Goodwin, P.R.1    Juo, P.2
  • 32
    • 84862253302 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons
    • Goodwin P.R., et al. Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. J. Neurosci. 2012, 32:8158-8172.
    • (2012) J. Neurosci. , vol.32 , pp. 8158-8172
    • Goodwin, P.R.1
  • 33
    • 0025844789 scopus 로고
    • Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans
    • Hall D.H., Hedgecock E.M. Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell 1991, 65:837-847.
    • (1991) Cell , vol.65 , pp. 837-847
    • Hall, D.H.1    Hedgecock, E.M.2
  • 34
    • 63249119849 scopus 로고    scopus 로고
    • The anaphase promoting complex induces substrate degradation during neuronal differentiation
    • Harmey D., et al. The anaphase promoting complex induces substrate degradation during neuronal differentiation. J. Biol. Chem. 2009, 284:4317-4323.
    • (2009) J. Biol. Chem. , vol.284 , pp. 4317-4323
    • Harmey, D.1
  • 35
    • 35748959676 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway in health and disease of the nervous system
    • Hegde A.N., Upadhya S.C. The ubiquitin-proteasome pathway in health and disease of the nervous system. Trends Neurosci. 2007, 30:587-595.
    • (2007) Trends Neurosci. , vol.30 , pp. 587-595
    • Hegde, A.N.1    Upadhya, S.C.2
  • 37
    • 0141442586 scopus 로고    scopus 로고
    • Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
    • Hicke L., Dunn R. Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Dev. Biol. 2003, 19:141-172.
    • (2003) Annu. Rev. Cell Dev. Biol. , vol.19 , pp. 141-172
    • Hicke, L.1    Dunn, R.2
  • 38
    • 34047107208 scopus 로고    scopus 로고
    • Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development
    • Hoogenraad C.C., et al. Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. Dev. Cell 2007, 12:587-602.
    • (2007) Dev. Cell , vol.12 , pp. 587-602
    • Hoogenraad, C.C.1
  • 39
    • 0034892146 scopus 로고    scopus 로고
    • Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type A (GABA(A)) receptors: mechanism and site of action
    • Huang R.Q., et al. Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type A (GABA(A)) receptors: mechanism and site of action. J. Pharmacol. Exp. Ther. 2001, 298:986-995.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 986-995
    • Huang, R.Q.1
  • 40
    • 65249129345 scopus 로고    scopus 로고
    • Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation
    • Huynh M.A., et al. Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation. J. Neurosci. 2009, 29:4322-4327.
    • (2009) J. Neurosci. , vol.29 , pp. 4322-4327
    • Huynh, M.A.1
  • 41
    • 0037444549 scopus 로고    scopus 로고
    • The EGL-21 carboxypeptidase E facilitates acetylcholine release at Caenorhabditis elegans neuromuscular junctions
    • Jacob T.C., Kaplan J.M. The EGL-21 carboxypeptidase E facilitates acetylcholine release at Caenorhabditis elegans neuromuscular junctions. J. Neurosci. 2003, 23:2122-2130.
    • (2003) J. Neurosci. , vol.23 , pp. 2122-2130
    • Jacob, T.C.1    Kaplan, J.M.2
  • 42
    • 0033556159 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development
    • Jin Y., et al. The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. J. Neurosci. 1999, 19:539-548.
    • (1999) J. Neurosci. , vol.19 , pp. 539-548
    • Jin, Y.1
  • 43
    • 9244263049 scopus 로고    scopus 로고
    • The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans
    • Juo P., Kaplan J.M. The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Curr. Biol. 2004, 14:2057-2062.
    • (2004) Curr. Biol. , vol.14 , pp. 2057-2062
    • Juo, P.1    Kaplan, J.M.2
  • 44
    • 0035229245 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
    • (RESEARCH0002)
    • Kamath R.S., et al. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2001, 2. (RESEARCH0002).
    • (2001) Genome Biol. , vol.2
    • Kamath, R.S.1
  • 45
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath R.S., et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003, 421:231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1
  • 46
    • 84870598651 scopus 로고    scopus 로고
    • P250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation
    • Kannan M., et al. p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation. PLoS One 2012, 7:e50735.
    • (2012) PLoS One , vol.7
    • Kannan, M.1
  • 47
    • 84865838325 scopus 로고    scopus 로고
    • The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth
    • Kannan M., et al. The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth. Development 2012, 139:3600-3612.
    • (2012) Development , vol.139 , pp. 3600-3612
    • Kannan, M.1
  • 48
    • 0037187643 scopus 로고    scopus 로고
    • Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis
    • Kaufmann N., et al. Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis. Neuron 2002, 34:27-38.
    • (2002) Neuron , vol.34 , pp. 27-38
    • Kaufmann, N.1
  • 49
    • 58249091452 scopus 로고    scopus 로고
    • A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons
    • Kim A.H., et al. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 2009, 136:322-336.
    • (2009) Cell , vol.136 , pp. 322-336
    • Kim, A.H.1
  • 50
    • 0037164720 scopus 로고    scopus 로고
    • The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans
    • Kitagawa R., et al. The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans. Curr. Biol. 2002, 12:2118-2123.
    • (2002) Curr. Biol. , vol.12 , pp. 2118-2123
    • Kitagawa, R.1
  • 51
    • 3342965153 scopus 로고    scopus 로고
    • The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans
    • Klopfenstein D.R., Vale R.D. The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans. Mol. Biol. Cell 2004, 15:3729-3739.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3729-3739
    • Klopfenstein, D.R.1    Vale, R.D.2
  • 52
    • 1142274208 scopus 로고    scopus 로고
    • Cdh1-APC controls axonal growth and patterning in the mammalian brain
    • Konishi Y., et al. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 2004, 303:1026-1030.
    • (2004) Science , vol.303 , pp. 1026-1030
    • Konishi, Y.1
  • 53
    • 0034810799 scopus 로고    scopus 로고
    • A post-docking role for active zone protein rim
    • Koushika S.P., et al. A post-docking role for active zone protein rim. Nat. Neurosci. 2001, 4:997-1005.
    • (2001) Nat. Neurosci. , vol.4 , pp. 997-1005
    • Koushika, S.P.1
  • 54
    • 84872163803 scopus 로고    scopus 로고
    • The role of deubiquitinating enzymes in synaptic function and nervous system diseases
    • Kowalski J.R., Juo P. The role of deubiquitinating enzymes in synaptic function and nervous system diseases. Neural Plast. 2012, 13.
    • (2012) Neural Plast. , pp. 13
    • Kowalski, J.R.1    Juo, P.2
  • 55
    • 78650984262 scopus 로고    scopus 로고
    • The anaphase promoting complex is required for memory function in mice
    • Kuczera T., et al. The anaphase promoting complex is required for memory function in mice. Learn. Mem. 2011, 18:49-57.
    • (2011) Learn. Mem. , vol.18 , pp. 49-57
    • Kuczera, T.1
  • 56
    • 84864222562 scopus 로고    scopus 로고
    • Atypical ubiquitylation -the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
    • Kulathu Y., Komander D. Atypical ubiquitylation -the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages. Nat. Rev. Mol. Cell Biol. 2012, 13:508-523.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 508-523
    • Kulathu, Y.1    Komander, D.2
  • 57
    • 33747087307 scopus 로고    scopus 로고
    • Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth
    • Lasorella A., et al. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature 2006, 442:471-474.
    • (2006) Nature , vol.442 , pp. 471-474
    • Lasorella, A.1
  • 58
    • 51049088378 scopus 로고    scopus 로고
    • The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
    • Li M., et al. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat. Cell Biol. 2008, 10:1083-1089.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1083-1089
    • Li, M.1
  • 59
    • 44949231368 scopus 로고    scopus 로고
    • Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
    • Li W., et al. Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS One 2008, 3:e1487.
    • (2008) PLoS One , vol.3
    • Li, W.1
  • 60
    • 33750481486 scopus 로고    scopus 로고
    • Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans
    • Locke C.J., et al. Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res. 2006, 1120:23-34.
    • (2006) Brain Res. , vol.1120 , pp. 23-34
    • Locke, C.J.1
  • 61
    • 80355148321 scopus 로고    scopus 로고
    • Paradigms for Pharmacological Characterization of C. elegans SynapticTransmission Mutants
    • Locke C., et al. Paradigms for Pharmacological Characterization of C. elegans SynapticTransmission Mutants. J. Vis. Exp. 2008, 18:e837. 10.3791/837.
    • (2008) J. Vis. Exp. , vol.18
    • Locke, C.1
  • 62
    • 71549147196 scopus 로고    scopus 로고
    • Pharmacogenetic analysis reveals a post-developmental role for Rac GTPases in Caenorhabditis elegans GABAergic neurotransmission
    • Locke C.J., et al. Pharmacogenetic analysis reveals a post-developmental role for Rac GTPases in Caenorhabditis elegans GABAergic neurotransmission. Genetics 2009, 183:1357-1372.
    • (2009) Genetics , vol.183 , pp. 1357-1372
    • Locke, C.J.1
  • 63
    • 35348931646 scopus 로고    scopus 로고
    • Mechanisms, biology and inhibitors of deubiquitinating enzymes
    • Love K.R., et al. Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat. Chem. Biol. 2007, 3:697-705.
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 697-705
    • Love, K.R.1
  • 64
    • 34248682392 scopus 로고    scopus 로고
    • Analysis of synaptic transmission in Caenorhabditis elegans using an aldicarb-sensitivity assay
    • Mahoney T.R., et al. Analysis of synaptic transmission in Caenorhabditis elegans using an aldicarb-sensitivity assay. Nat. Protoc. 2006, 1:1772-1777.
    • (2006) Nat. Protoc. , vol.1 , pp. 1772-1777
    • Mahoney, T.R.1
  • 65
    • 76449096769 scopus 로고    scopus 로고
    • The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions
    • Manchado E., et al. The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions. Biochem. Soc. Trans. 2012, 38:65-71.
    • (2012) Biochem. Soc. Trans. , vol.38 , pp. 65-71
    • Manchado, E.1
  • 66
    • 0041342029 scopus 로고    scopus 로고
    • Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties
    • Mathews E.A., et al. Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties. J. Neurosci. 2003, 23:6537-6545.
    • (2003) J. Neurosci. , vol.23 , pp. 6537-6545
    • Mathews, E.A.1
  • 67
    • 33746726458 scopus 로고    scopus 로고
    • Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13
    • McEwen J.M., et al. Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13. Neuron 2006, 51:303-315.
    • (2006) Neuron , vol.51 , pp. 303-315
    • McEwen, J.M.1
  • 68
    • 0027272707 scopus 로고
    • Genes required for GABA function in Caenorhabditis elegans
    • McIntire S.L., et al. Genes required for GABA function in Caenorhabditis elegans. Nature 1993, 364:334-337.
    • (1993) Nature , vol.364 , pp. 334-337
    • McIntire, S.L.1
  • 69
    • 0026571429 scopus 로고
    • C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
    • Miller D.M., et al. C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons. Nature 1992, 355:841-845.
    • (1992) Nature , vol.355 , pp. 841-845
    • Miller, D.M.1
  • 70
    • 0029914128 scopus 로고    scopus 로고
    • A genetic selection for Caenorhabditis elegans synaptic transmission mutants
    • Miller K.G., et al. A genetic selection for Caenorhabditis elegans synaptic transmission mutants. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:12593-12598.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 12593-12598
    • Miller, K.G.1
  • 71
    • 17144420913 scopus 로고    scopus 로고
    • Direct observation demonstrates that Liprin-alpha is required for trafficking of synaptic vesicles
    • Miller K.E., et al. Direct observation demonstrates that Liprin-alpha is required for trafficking of synaptic vesicles. Curr. Biol. 2005, 15:684-689.
    • (2005) Curr. Biol. , vol.15 , pp. 684-689
    • Miller, K.E.1
  • 72
    • 33748279259 scopus 로고    scopus 로고
    • Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
    • Miller J.J., et al. Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes Dev. 2006, 20:2410-2420.
    • (2006) Genes Dev. , vol.20 , pp. 2410-2420
    • Miller, J.J.1
  • 73
    • 0028848587 scopus 로고
    • Genetic regulation of mec-3 gene expression implicated in the specification of the mechanosensory neuron cell types in Caenorhabditis elegans
    • Mitani S. Genetic regulation of mec-3 gene expression implicated in the specification of the mechanosensory neuron cell types in Caenorhabditis elegans. Develop. Growth Differ. 1995, 37:551-557.
    • (1995) Develop. Growth Differ. , vol.37 , pp. 551-557
    • Mitani, S.1
  • 74
    • 0029053849 scopus 로고
    • Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase
    • Nguyen M., et al. Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase. Genetics 1995, 140:527-535.
    • (1995) Genetics , vol.140 , pp. 527-535
    • Nguyen, M.1
  • 75
    • 28344456279 scopus 로고    scopus 로고
    • A genomic and functional inventory of deubiquitinating enzymes
    • Nijman S.M., et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 2005, 123:773-786.
    • (2005) Cell , vol.123 , pp. 773-786
    • Nijman, S.M.1
  • 76
    • 0032769032 scopus 로고    scopus 로고
    • Visualization of synaptic specializations in live C. elegans with synaptic vesicle protein-GFP fusions
    • Nonet M.L. Visualization of synaptic specializations in live C. elegans with synaptic vesicle protein-GFP fusions. J. Neurosci. Methods 1999, 89:33-40.
    • (1999) J. Neurosci. Methods , vol.89 , pp. 33-40
    • Nonet, M.L.1
  • 77
    • 77953266051 scopus 로고    scopus 로고
    • Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components
    • Ou C.Y., et al. Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell 2010, 141:846-858.
    • (2010) Cell , vol.141 , pp. 846-858
    • Ou, C.Y.1
  • 78
    • 33845273849 scopus 로고    scopus 로고
    • Hierarchical assembly of presynaptic components in defined C. elegans synapses
    • Patel M.R., et al. Hierarchical assembly of presynaptic components in defined C. elegans synapses. Nat. Neurosci. 2006, 9:1488-1498.
    • (2006) Nat. Neurosci. , vol.9 , pp. 1488-1498
    • Patel, M.R.1
  • 79
    • 0036284778 scopus 로고    scopus 로고
    • The anaphase-promoting complex: proteolysis in mitosis and beyond
    • Peters J.M. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol. Cell 2002, 9:931-943.
    • (2002) Mol. Cell , vol.9 , pp. 931-943
    • Peters, J.M.1
  • 80
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: a machine designed to destroy
    • Peters J.M. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol. 2006, 7:644-656.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 644-656
    • Peters, J.M.1
  • 81
    • 84875472213 scopus 로고    scopus 로고
    • ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans
    • Petrash H.A., et al. ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans. J. Neurosci. 2013, 33:5524-5532.
    • (2013) J. Neurosci. , vol.33 , pp. 5524-5532
    • Petrash, H.A.1
  • 82
    • 84871830491 scopus 로고    scopus 로고
    • The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice
    • Pick J.E., et al. The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice. Learn. Mem. 2012, 20:11-20.
    • (2012) Learn. Mem. , vol.20 , pp. 11-20
    • Pick, J.E.1
  • 83
    • 0034948116 scopus 로고    scopus 로고
    • Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice
    • Prosser H.M., et al. Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Mol. Cell. Neurosci. 2001, 17:1059-1070.
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 1059-1070
    • Prosser, H.M.1
  • 84
    • 79959903981 scopus 로고    scopus 로고
    • Novel functions for the anaphase-promoting complex in neurobiology
    • Puram S.V., Bonni A. Novel functions for the anaphase-promoting complex in neurobiology. Semin. Cell Dev. Biol. 2011, 22:586-594.
    • (2011) Semin. Cell Dev. Biol. , vol.22 , pp. 586-594
    • Puram, S.V.1    Bonni, A.2
  • 85
    • 82555187507 scopus 로고    scopus 로고
    • Homeostatic strengthening of inhibitory synapses is mediated by the accumulation of GABA(A) receptors
    • Rannals M.D., Kapur J. Homeostatic strengthening of inhibitory synapses is mediated by the accumulation of GABA(A) receptors. J. Neurosci. 2011, 31:17701-17712.
    • (2011) J. Neurosci. , vol.31 , pp. 17701-17712
    • Rannals, M.D.1    Kapur, J.2
  • 86
    • 0035893917 scopus 로고    scopus 로고
    • Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
    • Reimann J.D., et al. Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Genes Dev. 2001, 15:3278-3285.
    • (2001) Genes Dev. , vol.15 , pp. 3278-3285
    • Reimann, J.D.1
  • 87
    • 0033361969 scopus 로고    scopus 로고
    • One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction
    • Richmond J.E., Jorgensen E.M. One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nat. Neurosci. 1999, 2:791-797.
    • (1999) Nat. Neurosci. , vol.2 , pp. 791-797
    • Richmond, J.E.1    Jorgensen, E.M.2
  • 88
    • 0033349884 scopus 로고    scopus 로고
    • UNC-13 is required for synaptic vesicle fusion in C. elegans
    • Richmond J.E., et al. UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat. Neurosci. 1999, 2:959-964.
    • (1999) Nat. Neurosci. , vol.2 , pp. 959-964
    • Richmond, J.E.1
  • 89
    • 0030560599 scopus 로고    scopus 로고
    • Pentylenetetrazol-induced kindling: early involvement of excitatory and inhibitory systems
    • Rocha L., et al. Pentylenetetrazol-induced kindling: early involvement of excitatory and inhibitory systems. Epilepsy Res. 1996, 26:105-113.
    • (1996) Epilepsy Res. , vol.26 , pp. 105-113
    • Rocha, L.1
  • 90
    • 33846503468 scopus 로고    scopus 로고
    • Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126)
    • Schmitz C., et al. Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Proc. Natl. Acad. Sci. U. S. A. 2007, 104:834-839.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 834-839
    • Schmitz, C.1
  • 91
    • 0035208462 scopus 로고    scopus 로고
    • Autistic syndrome
    • Schuler A.L. Autistic syndrome. Autism 2001, 5:331-340.
    • (2001) Autism , vol.5 , pp. 331-340
    • Schuler, A.L.1
  • 92
    • 0038067848 scopus 로고    scopus 로고
    • Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities
    • Shakes D.C., et al. Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities. Development 2003, 130:1605-1620.
    • (2003) Development , vol.130 , pp. 1605-1620
    • Shakes, D.C.1
  • 93
    • 23144441321 scopus 로고    scopus 로고
    • Systematic analysis of genes required for synapse structure and function
    • Sieburth D., et al. Systematic analysis of genes required for synapse structure and function. Nature 2005, 436:510-517.
    • (2005) Nature , vol.436 , pp. 510-517
    • Sieburth, D.1
  • 94
    • 0026547373 scopus 로고
    • GABA and epilepsy: their complex relationship and the evolution of our understanding
    • Snodgrass S.R. GABA and epilepsy: their complex relationship and the evolution of our understanding. J. Child Neurol. 1992, 7:77-86.
    • (1992) J. Child Neurol. , vol.7 , pp. 77-86
    • Snodgrass, S.R.1
  • 95
    • 84880000317 scopus 로고    scopus 로고
    • Liprin-alpha2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission
    • Spangler S.A., et al. Liprin-alpha2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. J. Cell Biol. 2013, 201:915-928.
    • (2013) J. Cell Biol. , vol.201 , pp. 915-928
    • Spangler, S.A.1
  • 96
    • 33646125845 scopus 로고    scopus 로고
    • Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN
    • Stegmuller J., et al. Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN. Neuron 2006, 50:389-400.
    • (2006) Neuron , vol.50 , pp. 389-400
    • Stegmuller, J.1
  • 97
    • 39749174970 scopus 로고    scopus 로고
    • TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis
    • Stegmuller J., et al. TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J. Neurosci. 2008, 28:1961-1969.
    • (2008) J. Neurosci. , vol.28 , pp. 1961-1969
    • Stegmuller, J.1
  • 98
    • 79952995749 scopus 로고    scopus 로고
    • The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions
    • Stigloher C., et al. The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions. J. Neurosci. 2011, 31:4388-4396.
    • (2011) J. Neurosci. , vol.31 , pp. 4388-4396
    • Stigloher, C.1
  • 99
    • 0021011925 scopus 로고
    • Neuronal cell lineages in the nematode Caenorhabditis elegans
    • Sulston J.E. Neuronal cell lineages in the nematode Caenorhabditis elegans. Cold Spring Harb. Symp. Quant. Biol. 1983, 48(Pt 2):443-452.
    • (1983) Cold Spring Harb. Symp. Quant. Biol. , vol.48 , Issue.PART 2 , pp. 443-452
    • Sulston, J.E.1
  • 100
    • 0017618537 scopus 로고
    • Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
    • Sulston J.E., Horvitz H.R. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol. 1977, 56:110-156.
    • (1977) Dev. Biol. , vol.56 , pp. 110-156
    • Sulston, J.E.1    Horvitz, H.R.2
  • 101
    • 0020858899 scopus 로고
    • The embryonic cell lineage of the nematode Caenorhabditis elegans
    • Sulston J.E., et al. The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 1983, 100:64-119.
    • (1983) Dev. Biol. , vol.100 , pp. 64-119
    • Sulston, J.E.1
  • 102
    • 84875058196 scopus 로고    scopus 로고
    • The F-Box Protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans
    • Sun Y., et al. The F-Box Protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans. PLoS One 2013, 8:e59132.
    • (2013) PLoS One , vol.8
    • Sun, Y.1
  • 103
    • 54249158324 scopus 로고    scopus 로고
    • Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
    • Tai H.C., Schuman E.M. Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction. Nat. Rev. Neurosci. 2008, 9:826-838.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 826-838
    • Tai, H.C.1    Schuman, E.M.2
  • 104
    • 22844452091 scopus 로고    scopus 로고
    • Acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction
    • Touroutine D., et al. acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction. J. Biol. Chem. 2005, 280:27013-27021.
    • (2005) J. Biol. Chem. , vol.280 , pp. 27013-27021
    • Touroutine, D.1
  • 105
    • 8844276742 scopus 로고    scopus 로고
    • Independent regulation of synaptic size and activity by the anaphase-promoting complex
    • Van Roessel P., et al. Independent regulation of synaptic size and activity by the anaphase-promoting complex. Cell 2004, 119:707-718.
    • (2004) Cell , vol.119 , pp. 707-718
    • Van Roessel, P.1
  • 106
    • 42949097579 scopus 로고    scopus 로고
    • An RNAi screen identifies genes that regulate GABA synapses
    • Vashlishan A.B., et al. An RNAi screen identifies genes that regulate GABA synapses. Neuron 2008, 58:346-361.
    • (2008) Neuron , vol.58 , pp. 346-361
    • Vashlishan, A.B.1
  • 107
    • 73349103185 scopus 로고    scopus 로고
    • Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans
    • Wagner O.I., et al. Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:19605-19610.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 19605-19610
    • Wagner, O.I.1
  • 108
    • 0141542671 scopus 로고    scopus 로고
    • Defects in synaptic vesicle docking in unc-18 mutants
    • Weimer R.M., et al. Defects in synaptic vesicle docking in unc-18 mutants. Nat. Neurosci. 2003, 6:1023-1030.
    • (2003) Nat. Neurosci. , vol.6 , pp. 1023-1030
    • Weimer, R.M.1
  • 109
    • 80053618522 scopus 로고    scopus 로고
    • Mechanisms of GABAergic homeostatic plasticity
    • Wenner P. Mechanisms of GABAergic homeostatic plasticity. Neural Plast. 2011, 2011:489470.
    • (2011) Neural Plast. , vol.2011 , pp. 489470
    • Wenner, P.1
  • 110
    • 0002221492 scopus 로고
    • The structure of the nervous system of the nematode Caenorhabditis elegans
    • White J.G., et al. The structure of the nervous system of the nematode Caenorhabditis elegans. Philos. Trans. R. Soc. Lond. B Biol. Sci. 1986, 314:1-340.
    • (1986) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.314 , pp. 1-340
    • White, J.G.1
  • 111
    • 4644264353 scopus 로고    scopus 로고
    • Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in Caenorhabditis elegans
    • Williams S.N., et al. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in Caenorhabditis elegans. Hum. Mol. Genet. 2004, 13:2043-2059.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2043-2059
    • Williams, S.N.1
  • 112
    • 70350514911 scopus 로고    scopus 로고
    • A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
    • Yang Y., et al. A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science 2009, 326:575-578.
    • (2009) Science , vol.326 , pp. 575-578
    • Yang, Y.1
  • 113
    • 74349107487 scopus 로고    scopus 로고
    • Cdh1-APC is involved in the differentiation of neural stem cells into neurons
    • Yao W., et al. Cdh1-APC is involved in the differentiation of neural stem cells into neurons. Neuroreport 2010, 21:39-44.
    • (2010) Neuroreport , vol.21 , pp. 39-44
    • Yao, W.1
  • 114
    • 70350461507 scopus 로고    scopus 로고
    • Building ubiquitin chains: E2 enzymes at work
    • Ye Y., Rape M. Building ubiquitin chains: E2 enzymes at work. Nat. Rev. Mol. Cell Biol. 2009, 10:755-764.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 755-764
    • Ye, Y.1    Rape, M.2
  • 115
    • 17644416105 scopus 로고    scopus 로고
    • Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans
    • Yeh E., et al. Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans. J. Neurosci. 2005, 25:3833-3841.
    • (2005) J. Neurosci. , vol.25 , pp. 3833-3841
    • Yeh, E.1
  • 116
    • 33847410541 scopus 로고    scopus 로고
    • Emerging roles for ubiquitin and protein degradation in neuronal function
    • Yi J.J., Ehlers M.D. Emerging roles for ubiquitin and protein degradation in neuronal function. Pharmacol. Rev. 2007, 59:14-39.
    • (2007) Pharmacol. Rev. , vol.59 , pp. 14-39
    • Yi, J.J.1    Ehlers, M.D.2
  • 117
    • 84859509100 scopus 로고    scopus 로고
    • Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease
    • Yuen E.Y., et al. Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease. Neurobiol. Dis. 2012, 46:497-502.
    • (2012) Neurobiol. Dis. , vol.46 , pp. 497-502
    • Yuen, E.Y.1
  • 118
    • 3142760056 scopus 로고    scopus 로고
    • Dense core vesicle dynamics in Caenorhabditis elegans neurons and the role of kinesin UNC-104
    • Zahn T.R., et al. Dense core vesicle dynamics in Caenorhabditis elegans neurons and the role of kinesin UNC-104. Traffic 2004, 5:544-559.
    • (2004) Traffic , vol.5 , pp. 544-559
    • Zahn, T.R.1
  • 119
    • 0033598333 scopus 로고    scopus 로고
    • The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans
    • Zhen M., Jin Y. The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. Nature 1999, 401:371-375.
    • (1999) Nature , vol.401 , pp. 371-375
    • Zhen, M.1    Jin, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.