Disrupted GABA AR trafficking and synaptic inhibition in a mouse model of Huntington's disease

Neurobiology of Disease

Volumn 46, Issue 2, 2012, Pages 497-502

  Yuen, Eunice Y ^a   Wei, Jing ^a   Zhong, Ping ^a   Yan, Zhen ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

GABA A receptor; Huntingtin; IPSC; KIF5; Microtubule; Trafficking

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; HUNTINGTIN; KINESIN; POLYGLUTAMINE; PROTEIN HAP1; PROTEIN KIF5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; EXCITATORY POSTSYNAPTIC POTENTIAL; HUNTINGTON CHOREA; INHIBITORY POSTSYNAPTIC POTENTIAL; INTRACELLULAR TRANSPORT; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE; ANIMAL; METABOLISM; NERVE CELL INHIBITION; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; DISEASE MODELS, ANIMAL; HUNTINGTON DISEASE; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE; MICE, TRANSGENIC; MICROTUBULES; NEURAL INHIBITION; PROTEIN TRANSPORT; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 84859509100     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.02.015     Document Type: Article

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