메뉴 건너뛰기




Volumn 22, Issue 6, 2011, Pages 586-594

Novel functions for the anaphase-promoting complex in neurobiology

Author keywords

Axons; Cdc20 APC; Cdh1 APC; Dendrites; Synapses

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN 20; PROTEASOME; UVOMORULIN;

EID: 79959903981     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2011.03.006     Document Type: Review
Times cited : (35)

References (77)
  • 1
    • 78049395303 scopus 로고    scopus 로고
    • Ubiquitination in postsynaptic function and plasticity
    • Mabb A.M., Ehlers M.D. Ubiquitination in postsynaptic function and plasticity. Annu Rev Cell Dev Biol 2010, 26:179-210.
    • (2010) Annu Rev Cell Dev Biol , vol.26 , pp. 179-210
    • Mabb, A.M.1    Ehlers, M.D.2
  • 2
    • 0037179795 scopus 로고    scopus 로고
    • New roles for ubiquitin in the assembly and function of neuronal circuits
    • Murphey R.K., Godenschwege T.A. New roles for ubiquitin in the assembly and function of neuronal circuits. Neuron 2002, 36:5-8.
    • (2002) Neuron , vol.36 , pp. 5-8
    • Murphey, R.K.1    Godenschwege, T.A.2
  • 3
    • 76749162906 scopus 로고    scopus 로고
    • The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity
    • Yang Y., Kim A.H., Bonni A. The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity. Curr Opin Neurobiol 2010, 20:92-99.
    • (2010) Curr Opin Neurobiol , vol.20 , pp. 92-99
    • Yang, Y.1    Kim, A.H.2    Bonni, A.3
  • 4
    • 1142274208 scopus 로고    scopus 로고
    • Cdh1-APC controls axonal growth and patterning in the mammalian brain
    • Konishi Y., Stegmuller J., Matsuda T., Bonni S., Bonni A. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 2004, 303:1026-1030.
    • (2004) Science , vol.303 , pp. 1026-1030
    • Konishi, Y.1    Stegmuller, J.2    Matsuda, T.3    Bonni, S.4    Bonni, A.5
  • 5
    • 33847633885 scopus 로고    scopus 로고
    • Thinking within the D box: initial identification of Cdh1-APC substrates in the nervous system
    • Kim A.H., Bonni A. Thinking within the D box: initial identification of Cdh1-APC substrates in the nervous system. Mol Cell Neurosci 2007, 34:281-287.
    • (2007) Mol Cell Neurosci , vol.34 , pp. 281-287
    • Kim, A.H.1    Bonni, A.2
  • 6
    • 26944445014 scopus 로고    scopus 로고
    • Moving past proliferation: new roles for Cdh1-APC in postmitotic neurons
    • Stegmuller J., Bonni A. Moving past proliferation: new roles for Cdh1-APC in postmitotic neurons. Trends Neurosci 2005, 28:596-601.
    • (2005) Trends Neurosci , vol.28 , pp. 596-601
    • Stegmuller, J.1    Bonni, A.2
  • 7
    • 0029004815 scopus 로고
    • A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
    • King R.W., Peters J.M., Tugendreich S., Rolfe M., Hieter P., Kirschner M.W. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 1995, 81:279-288.
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.W.1    Peters, J.M.2    Tugendreich, S.3    Rolfe, M.4    Hieter, P.5    Kirschner, M.W.6
  • 8
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
    • Irniger S., Piatti S., Michaelis C., Nasmyth K. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 1995, 81:269-278.
    • (1995) Cell , vol.81 , pp. 269-278
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 9
    • 0036713310 scopus 로고    scopus 로고
    • The anaphase-promoting complex: it's not just for mitosis any more
    • Harper J.W., Burton J.L., Solomon M.J. The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev 2002, 16:2179-2206.
    • (2002) Genes Dev , vol.16 , pp. 2179-2206
    • Harper, J.W.1    Burton, J.L.2    Solomon, M.J.3
  • 10
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: a machine designed to destroy
    • Peters J.M. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 2006, 7:644-656.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 644-656
    • Peters, J.M.1
  • 11
    • 29144527503 scopus 로고    scopus 로고
    • Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C
    • Dube P., Herzog F., Gieffers C., Sander B., Riedel D., Muller S.A., et al. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Mol Cell 2005, 20:867-879.
    • (2005) Mol Cell , vol.20 , pp. 867-879
    • Dube, P.1    Herzog, F.2    Gieffers, C.3    Sander, B.4    Riedel, D.5    Muller, S.A.6
  • 12
    • 0026089183 scopus 로고
    • Cyclin is degraded by the ubiquitin pathway
    • Glotzer M., Murray A.W., Kirschner M.W. Cyclin is degraded by the ubiquitin pathway. Nature 1991, 349:132-138.
    • (1991) Nature , vol.349 , pp. 132-138
    • Glotzer, M.1    Murray, A.W.2    Kirschner, M.W.3
  • 13
    • 0036714512 scopus 로고    scopus 로고
    • Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit
    • Littlepage L.E., Ruderman J.V. Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes Dev 2002, 16:2274-2285.
    • (2002) Genes Dev , vol.16 , pp. 2274-2285
    • Littlepage, L.E.1    Ruderman, J.V.2
  • 14
    • 0034654399 scopus 로고    scopus 로고
    • The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1
    • Pfleger C.M., Kirschner M.W. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev 2000, 14:655-665.
    • (2000) Genes Dev , vol.14 , pp. 655-665
    • Pfleger, C.M.1    Kirschner, M.W.2
  • 15
    • 33749243774 scopus 로고    scopus 로고
    • The CRY box: a second APCcdh1-dependent degron in mammalian cdc20
    • Reis A., Levasseur M., Chang H.Y., Elliott D.J., Jones K.T. The CRY box: a second APCcdh1-dependent degron in mammalian cdc20. EMBO Rep 2006, 7:1040-1045.
    • (2006) EMBO Rep , vol.7 , pp. 1040-1045
    • Reis, A.1    Levasseur, M.2    Chang, H.Y.3    Elliott, D.J.4    Jones, K.T.5
  • 16
    • 0033147334 scopus 로고    scopus 로고
    • Regulation of the APC and the exit from mitosis
    • Morgan D.O. Regulation of the APC and the exit from mitosis. Nat Cell Biol 1999, 1:E47-53.
    • (1999) Nat Cell Biol , vol.1
    • Morgan, D.O.1
  • 17
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio A., Salmon E.D. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007, 8:379-393.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 18
    • 49849098630 scopus 로고    scopus 로고
    • Regulation of APC/C activators in mitosis and meiosis
    • Pesin J.A., Orr-Weaver T.L. Regulation of APC/C activators in mitosis and meiosis. Annu Rev Cell Dev Biol 2008, 24:475-499.
    • (2008) Annu Rev Cell Dev Biol , vol.24 , pp. 475-499
    • Pesin, J.A.1    Orr-Weaver, T.L.2
  • 19
    • 34250799719 scopus 로고    scopus 로고
    • Cdc20: a WD40 activator for a cell cycle degradation machine
    • Yu H. Cdc20: a WD40 activator for a cell cycle degradation machine. Mol Cell 2007, 27:3-16.
    • (2007) Mol Cell , vol.27 , pp. 3-16
    • Yu, H.1
  • 20
    • 0033613270 scopus 로고    scopus 로고
    • Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons
    • Gieffers C., Peters B.H., Kramer E.R., Dotti C.G., Peters J.M. Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons. Proc Natl Acad Sci U S A 1999, 96:11317-11322.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11317-11322
    • Gieffers, C.1    Peters, B.H.2    Kramer, E.R.3    Dotti, C.G.4    Peters, J.M.5
  • 21
    • 58249091452 scopus 로고    scopus 로고
    • A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons
    • Kim A.H., Puram S.V., Bilimoria P.M., Ikeuchi Y., Keough S., Wong M., et al. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 2009, 136:322-336.
    • (2009) Cell , vol.136 , pp. 322-336
    • Kim, A.H.1    Puram, S.V.2    Bilimoria, P.M.3    Ikeuchi, Y.4    Keough, S.5    Wong, M.6
  • 22
    • 65249129345 scopus 로고    scopus 로고
    • Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation
    • Huynh M.A., Stegmuller J., Litterman N., Bonni A. Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation. J Neurosci 2009, 29:4322-4327.
    • (2009) J Neurosci , vol.29 , pp. 4322-4327
    • Huynh, M.A.1    Stegmuller, J.2    Litterman, N.3    Bonni, A.4
  • 23
    • 65249104139 scopus 로고    scopus 로고
    • A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain
    • Ikeuchi Y., Stegmuller J., Netherton S., Huynh M.A., Masu M., Frank D., et al. A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain. J Neurosci 2009, 29:4312-4321.
    • (2009) J Neurosci , vol.29 , pp. 4312-4321
    • Ikeuchi, Y.1    Stegmuller, J.2    Netherton, S.3    Huynh, M.A.4    Masu, M.5    Frank, D.6
  • 24
    • 33747087307 scopus 로고    scopus 로고
    • Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth
    • Lasorella A., Stegmuller J., Guardavaccaro D., Liu G., Carro M.S., Rothschild G., et al. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature 2006, 442:471-474.
    • (2006) Nature , vol.442 , pp. 471-474
    • Lasorella, A.1    Stegmuller, J.2    Guardavaccaro, D.3    Liu, G.4    Carro, M.S.5    Rothschild, G.6
  • 25
    • 39749174970 scopus 로고    scopus 로고
    • TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis
    • Stegmuller J., Huynh M.A., Yuan Z., Konishi Y., Bonni A. TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J Neurosci 2008, 28:1961-1969.
    • (2008) J Neurosci , vol.28 , pp. 1961-1969
    • Stegmuller, J.1    Huynh, M.A.2    Yuan, Z.3    Konishi, Y.4    Bonni, A.5
  • 26
    • 33646125845 scopus 로고    scopus 로고
    • Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN
    • Stegmuller J., Konishi Y., Huynh M.A., Yuan Z., Dibacco S., Bonni A. Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN. Neuron 2006, 50:389-400.
    • (2006) Neuron , vol.50 , pp. 389-400
    • Stegmuller, J.1    Konishi, Y.2    Huynh, M.A.3    Yuan, Z.4    Dibacco, S.5    Bonni, A.6
  • 27
    • 0035498980 scopus 로고    scopus 로고
    • Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
    • Stroschein S.L., Bonni S., Wrana J.L., Luo K. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes Dev 2001, 15:2822-2836.
    • (2001) Genes Dev , vol.15 , pp. 2822-2836
    • Stroschein, S.L.1    Bonni, S.2    Wrana, J.L.3    Luo, K.4
  • 28
    • 0035930333 scopus 로고    scopus 로고
    • The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction
    • Wan Y., Liu X., Kirschner M.W. The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction. Mol Cell 2001, 8:1027-1039.
    • (2001) Mol Cell , vol.8 , pp. 1027-1039
    • Wan, Y.1    Liu, X.2    Kirschner, M.W.3
  • 29
    • 5344265069 scopus 로고    scopus 로고
    • Intrinsic neuronal regulation of axon and dendrite growth
    • Goldberg J.L. Intrinsic neuronal regulation of axon and dendrite growth. Curr Opin Neurobiol 2004, 14:551-557.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 551-557
    • Goldberg, J.L.1
  • 30
    • 32344447055 scopus 로고    scopus 로고
    • Neural map specification by gradients
    • Flanagan J.G. Neural map specification by gradients. Curr Opin Neurobiol 2006, 16:59-66.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 59-66
    • Flanagan, J.G.1
  • 31
    • 41149102101 scopus 로고    scopus 로고
    • Development of continuous and discrete neural maps
    • Luo L., Flanagan J.G. Development of continuous and discrete neural maps. Neuron 2007, 56:284-300.
    • (2007) Neuron , vol.56 , pp. 284-300
    • Luo, L.1    Flanagan, J.G.2
  • 32
    • 33847410600 scopus 로고    scopus 로고
    • Getting axons onto the right path: the role of transcription factors in axon guidance
    • Butler S.J., Tear G. Getting axons onto the right path: the role of transcription factors in axon guidance. Development 2007, 134:439-448.
    • (2007) Development , vol.134 , pp. 439-448
    • Butler, S.J.1    Tear, G.2
  • 33
    • 34247516542 scopus 로고    scopus 로고
    • Transcriptional regulation of vertebrate axon guidance and synapse formation
    • Polleux F., Ince-Dunn G., Ghosh A. Transcriptional regulation of vertebrate axon guidance and synapse formation. Nat Rev Neurosci 2007, 8:331-340.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 331-340
    • Polleux, F.1    Ince-Dunn, G.2    Ghosh, A.3
  • 35
    • 0842281496 scopus 로고    scopus 로고
    • Ski and SnoN: negative regulators of TGF-beta signaling
    • Luo K. Ski and SnoN: negative regulators of TGF-beta signaling. Curr Opin Genet Dev 2004, 14:65-70.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 65-70
    • Luo, K.1
  • 36
    • 47249123054 scopus 로고    scopus 로고
    • SnoN in TGF-beta signaling and cancer biology
    • Pot I., Bonni S. SnoN in TGF-beta signaling and cancer biology. Curr Mol Med 2008, 8:319-328.
    • (2008) Curr Mol Med , vol.8 , pp. 319-328
    • Pot, I.1    Bonni, S.2
  • 37
    • 45149095522 scopus 로고    scopus 로고
    • ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells
    • Sarker K.P., Kataoka H., Chan A., Netherton S.J., Pot I., Huynh M.A., et al. ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells. J Biol Chem 2008, 283:13269-13279.
    • (2008) J Biol Chem , vol.283 , pp. 13269-13279
    • Sarker, K.P.1    Kataoka, H.2    Chan, A.3    Netherton, S.J.4    Pot, I.5    Huynh, M.A.6
  • 38
    • 16844379237 scopus 로고    scopus 로고
    • SnoN is a cell type-specific mediator of transforming growth factor-beta responses
    • Sarker K.P., Wilson S.M., Bonni S. SnoN is a cell type-specific mediator of transforming growth factor-beta responses. J Biol Chem 2005, 280:13037-13046.
    • (2005) J Biol Chem , vol.280 , pp. 13037-13046
    • Sarker, K.P.1    Wilson, S.M.2    Bonni, S.3
  • 39
    • 33748689930 scopus 로고    scopus 로고
    • Activated c-Jun N-terminal kinase is required for axon formation
    • Oliva A.A., Atkins C.M., Copenagle L., Banker G.A. Activated c-Jun N-terminal kinase is required for axon formation. J Neurosci 2006, 26:9462-9470.
    • (2006) J Neurosci , vol.26 , pp. 9462-9470
    • Oliva, A.A.1    Atkins, C.M.2    Copenagle, L.3    Banker, G.A.4
  • 40
    • 0025238437 scopus 로고
    • The protein Id: a negative regulator of helix-loop-helix DNA binding proteins
    • Benezra R., Davis R.L., Lockshon D., Turner D.L., Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 1990, 61:49-59.
    • (1990) Cell , vol.61 , pp. 49-59
    • Benezra, R.1    Davis, R.L.2    Lockshon, D.3    Turner, D.L.4    Weintraub, H.5
  • 41
    • 77951915557 scopus 로고    scopus 로고
    • An old dog learns new tricks: a novel function for Cdc20-APC in dendrite morphogenesis in neurons
    • Puram S.V., Kim A.H., Bonni A. An old dog learns new tricks: a novel function for Cdc20-APC in dendrite morphogenesis in neurons. Cell Cycle 2010, 9:482-485.
    • (2010) Cell Cycle , vol.9 , pp. 482-485
    • Puram, S.V.1    Kim, A.H.2    Bonni, A.3
  • 42
    • 34250758641 scopus 로고    scopus 로고
    • HEF1-dependent Aurora A activation induces disassembly of the primary cilium
    • Pugacheva E.N., Jablonski S.A., Hartman T.R., Henske E.P., Golemis E.A. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell 2007, 129:1351-1363.
    • (2007) Cell , vol.129 , pp. 1351-1363
    • Pugacheva, E.N.1    Jablonski, S.A.2    Hartman, T.R.3    Henske, E.P.4    Golemis, E.A.5
  • 43
    • 30344466977 scopus 로고    scopus 로고
    • The processivity of multiubiquitination by the APC determines the order of substrate degradation
    • Rape M., Reddy S.K., Kirschner M.W. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 2006, 124:89-103.
    • (2006) Cell , vol.124 , pp. 89-103
    • Rape, M.1    Reddy, S.K.2    Kirschner, M.W.3
  • 44
    • 34247355517 scopus 로고    scopus 로고
    • Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
    • Reddy S.K., Rape M., Margansky W.A., Kirschner M.W. Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature 2007, 446:921-925.
    • (2007) Nature , vol.446 , pp. 921-925
    • Reddy, S.K.1    Rape, M.2    Margansky, W.A.3    Kirschner, M.W.4
  • 45
    • 9244263049 scopus 로고    scopus 로고
    • The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans
    • Juo P., Kaplan J.M. The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Curr Biol 2004, 14:2057-2062.
    • (2004) Curr Biol , vol.14 , pp. 2057-2062
    • Juo, P.1    Kaplan, J.M.2
  • 46
    • 8844276742 scopus 로고    scopus 로고
    • Independent regulation of synaptic size and activity by the anaphase-promoting complex
    • van Roessel P., Elliott D.A., Robinson I.M., Prokop A., Brand A.H. Independent regulation of synaptic size and activity by the anaphase-promoting complex. Cell 2004, 119:707-718.
    • (2004) Cell , vol.119 , pp. 707-718
    • van Roessel, P.1    Elliott, D.A.2    Robinson, I.M.3    Prokop, A.4    Brand, A.H.5
  • 47
    • 79251584863 scopus 로고    scopus 로고
    • APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity
    • Fu A.K., Hung K.W., Fu W.Y., Shen C., Chen Y., Xia J., et al. APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity. Nat Neurosci 2011, 14:181-189.
    • (2011) Nat Neurosci , vol.14 , pp. 181-189
    • Fu, A.K.1    Hung, K.W.2    Fu, W.Y.3    Shen, C.4    Chen, Y.5    Xia, J.6
  • 48
    • 51049088378 scopus 로고    scopus 로고
    • The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
    • Li M., Shin Y.H., Hou L., Huang X., Wei Z., Klann E., et al. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol 2008, 10:1083-1089.
    • (2008) Nat Cell Biol , vol.10 , pp. 1083-1089
    • Li, M.1    Shin, Y.H.2    Hou, L.3    Huang, X.4    Wei, Z.5    Klann, E.6
  • 50
    • 77954161955 scopus 로고    scopus 로고
    • Releasing the brake on presynaptic development: Cdc20-APC triggers neuroD2 degradation to drive presynaptic differentiation
    • Yang Y., Bonni A. Releasing the brake on presynaptic development: Cdc20-APC triggers neuroD2 degradation to drive presynaptic differentiation. Cell Cycle 2010, 9.
    • (2010) Cell Cycle , pp. 9
    • Yang, Y.1    Bonni, A.2
  • 51
    • 70350514911 scopus 로고    scopus 로고
    • A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
    • Yang Y., Kim A.H., Yamada T., Wu B., Bilimoria P.M., Ikeuchi Y., et al. A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science 2009, 326:575-578.
    • (2009) Science , vol.326 , pp. 575-578
    • Yang, Y.1    Kim, A.H.2    Yamada, T.3    Wu, B.4    Bilimoria, P.M.5    Ikeuchi, Y.6
  • 52
    • 34748846347 scopus 로고    scopus 로고
    • A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth
    • Huntwork S., Littleton J.T. A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth. Nat Neurosci 2007, 10:1235-1237.
    • (2007) Nat Neurosci , vol.10 , pp. 1235-1237
    • Huntwork, S.1    Littleton, J.T.2
  • 53
    • 0035846908 scopus 로고    scopus 로고
    • Complexins regulate a late step in Ca2+-dependent neurotransmitter release
    • Reim K., Mansour M., Varoqueaux F., McMahon H.T., Sudhof T.C., Brose N., et al. Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell 2001, 104:71-81.
    • (2001) Cell , vol.104 , pp. 71-81
    • Reim, K.1    Mansour, M.2    Varoqueaux, F.3    McMahon, H.T.4    Sudhof, T.C.5    Brose, N.6
  • 54
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker E.B., Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 2004, 72:1-25.
    • (2004) Prog Neurobiol , vol.72 , pp. 1-25
    • Becker, E.B.1    Bonni, A.2
  • 55
    • 1642433100 scopus 로고    scopus 로고
    • Cell cycle molecules and vertebrate neuron death: E2F at the hub
    • Greene L.A., Biswas S.C., Liu D.X. Cell cycle molecules and vertebrate neuron death: E2F at the hub. Cell Death Differ 2004, 11:49-60.
    • (2004) Cell Death Differ , vol.11 , pp. 49-60
    • Greene, L.A.1    Biswas, S.C.2    Liu, D.X.3
  • 56
    • 0034923671 scopus 로고    scopus 로고
    • Neuronal apoptosis at the G1/S cell cycle checkpoint
    • Liu D.X., Greene L.A. Neuronal apoptosis at the G1/S cell cycle checkpoint. Cell Tissue Res 2001, 305:217-228.
    • (2001) Cell Tissue Res , vol.305 , pp. 217-228
    • Liu, D.X.1    Greene, L.A.2
  • 57
    • 24744467563 scopus 로고    scopus 로고
    • Cdh1/Hct1-APC is essential for the survival of postmitotic neurons
    • Almeida A., Bolanos J.P., Moreno S. Cdh1/Hct1-APC is essential for the survival of postmitotic neurons. J Neurosci 2005, 25:8115-8121.
    • (2005) J Neurosci , vol.25 , pp. 8115-8121
    • Almeida, A.1    Bolanos, J.P.2    Moreno, S.3
  • 58
    • 0036282745 scopus 로고    scopus 로고
    • Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
    • Konishi Y., Lehtinen M., Donovan N., Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 2002, 9:1005-1016.
    • (2002) Mol Cell , vol.9 , pp. 1005-1016
    • Konishi, Y.1    Lehtinen, M.2    Donovan, N.3    Bonni, A.4
  • 59
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A., McDonnell J.M., Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999, 13:1899-1911.
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 60
    • 0037335443 scopus 로고    scopus 로고
    • The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons
    • Konishi Y., Bonni A. The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. J Neurosci 2003, 23:1649-1658.
    • (2003) J Neurosci , vol.23 , pp. 1649-1658
    • Konishi, Y.1    Bonni, A.2
  • 61
    • 41149160386 scopus 로고    scopus 로고
    • Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons
    • Yuan Z., Becker E.B., Merlo P., Yamada T., DiBacco S., Konishi Y., et al. Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons. Science 2008, 319:1665-1668.
    • (2008) Science , vol.319 , pp. 1665-1668
    • Yuan, Z.1    Becker, E.B.2    Merlo, P.3    Yamada, T.4    DiBacco, S.5    Konishi, Y.6
  • 62
    • 0032522911 scopus 로고    scopus 로고
    • Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain
    • Busser J., Geldmacher D.S., Herrup K. Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J Neurosci 1998, 18:2801-2807.
    • (1998) J Neurosci , vol.18 , pp. 2801-2807
    • Busser, J.1    Geldmacher, D.S.2    Herrup, K.3
  • 63
    • 0031006939 scopus 로고    scopus 로고
    • Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
    • Vincent I., Jicha G., Rosado M., Dickson D.W. Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci 1997, 17:3588-3598.
    • (1997) J Neurosci , vol.17 , pp. 3588-3598
    • Vincent, I.1    Jicha, G.2    Rosado, M.3    Dickson, D.W.4
  • 64
    • 0033635551 scopus 로고    scopus 로고
    • Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases
    • Husseman J.W., Nochlin D., Vincent I. Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases. Neurobiol Aging 2000, 21:815-828.
    • (2000) Neurobiol Aging , vol.21 , pp. 815-828
    • Husseman, J.W.1    Nochlin, D.2    Vincent, I.3
  • 65
    • 0033551712 scopus 로고    scopus 로고
    • Cell cycle-related protein expression in vascular dementia and Alzheimer's disease
    • Smith M.Z., Nagy Z., Esiri M.M. Cell cycle-related protein expression in vascular dementia and Alzheimer's disease. Neurosci Lett 1999, 271:45-48.
    • (1999) Neurosci Lett , vol.271 , pp. 45-48
    • Smith, M.Z.1    Nagy, Z.2    Esiri, M.M.3
  • 67
    • 74349107487 scopus 로고    scopus 로고
    • Cdh1-APC is involved in the differentiation of neural stem cells into neurons
    • Yao W., Qian W., Zhu C., Gui L., Qiu J., Zhang C. Cdh1-APC is involved in the differentiation of neural stem cells into neurons. Neuroreport 2010, 21:39-44.
    • (2010) Neuroreport , vol.21 , pp. 39-44
    • Yao, W.1    Qian, W.2    Zhu, C.3    Gui, L.4    Qiu, J.5    Zhang, C.6
  • 68
    • 44349121372 scopus 로고    scopus 로고
    • Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation
    • Cuende J., Moreno S., Bolanos J.P., Almeida A. Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation. Oncogene 2008, 27:3339-3344.
    • (2008) Oncogene , vol.27 , pp. 3339-3344
    • Cuende, J.1    Moreno, S.2    Bolanos, J.P.3    Almeida, A.4
  • 69
    • 0035824670 scopus 로고    scopus 로고
    • Retinoic acid-mediated growth arrest requires ubiquitylation and degradation of the F-box protein Skp2
    • Dow R., Hendley J., Pirkmaier A., Musgrove E.A., Germain D. Retinoic acid-mediated growth arrest requires ubiquitylation and degradation of the F-box protein Skp2. J Biol Chem 2001, 276:45945-45951.
    • (2001) J Biol Chem , vol.276 , pp. 45945-45951
    • Dow, R.1    Hendley, J.2    Pirkmaier, A.3    Musgrove, E.A.4    Germain, D.5
  • 70
    • 0038026135 scopus 로고    scopus 로고
    • Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2
    • Nakamura M., Matsuo T., Stauffer J., Neckers L., Thiele C.J. Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2. Cell Death Differ 2003, 10:230-239.
    • (2003) Cell Death Differ , vol.10 , pp. 230-239
    • Nakamura, M.1    Matsuo, T.2    Stauffer, J.3    Neckers, L.4    Thiele, C.J.5
  • 71
    • 17844410708 scopus 로고    scopus 로고
    • Retinoic acid stabilizes p27Kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45Skp2 and Cks1 proteins
    • Zancai P., Dal Col J., Piccinin S., Guidoboni M., Cariati R., Rizzo S., et al. Retinoic acid stabilizes p27Kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45Skp2 and Cks1 proteins. Oncogene 2005, 24:2483-2494.
    • (2005) Oncogene , vol.24 , pp. 2483-2494
    • Zancai, P.1    Dal Col, J.2    Piccinin, S.3    Guidoboni, M.4    Cariati, R.5    Rizzo, S.6
  • 72
    • 63249119849 scopus 로고    scopus 로고
    • The anaphase promoting complex induces substrate degradation during neuronal differentiation
    • Harmey D., Smith A., Simanski S., Moussa C.Z., Ayad N.G. The anaphase promoting complex induces substrate degradation during neuronal differentiation. J Biol Chem 2009, 284:4317-4323.
    • (2009) J Biol Chem , vol.284 , pp. 4317-4323
    • Harmey, D.1    Smith, A.2    Simanski, S.3    Moussa, C.Z.4    Ayad, N.G.5
  • 73
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • Herrero-Mendez A., Almeida A., Fernandez E., Maestre C., Moncada S., Bolanos J.P. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat Cell Biol 2009, 11:747-752.
    • (2009) Nat Cell Biol , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernandez, E.3    Maestre, C.4    Moncada, S.5    Bolanos, J.P.6
  • 74
    • 78049268480 scopus 로고    scopus 로고
    • APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS
    • Silies M., Klambt C. APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS. Nat Neurosci 2010, 13:1357-1364.
    • (2010) Nat Neurosci , vol.13 , pp. 1357-1364
    • Silies, M.1    Klambt, C.2
  • 75
    • 45849083929 scopus 로고    scopus 로고
    • Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein
    • Kaplow M.E., Korayem A.H., Venkatesh T.R. Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein. Genetics 2008, 178:2003-2016.
    • (2008) Genetics , vol.178 , pp. 2003-2016
    • Kaplow, M.E.1    Korayem, A.H.2    Venkatesh, T.R.3
  • 76
    • 4444318673 scopus 로고    scopus 로고
    • The SCF ubiquitin ligase: insights into a molecular machine
    • Cardozo T., Pagano M. The SCF ubiquitin ligase: insights into a molecular machine. Nat Rev Mol Cell Biol 2004, 5:739-751.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 739-751
    • Cardozo, T.1    Pagano, M.2
  • 77
    • 33646345376 scopus 로고    scopus 로고
    • Ubiquitin ligases: cell-cycle control and cancer
    • Nakayama K.I., Nakayama K. Ubiquitin ligases: cell-cycle control and cancer. Nat Rev Cancer 2006, 6:369-381.
    • (2006) Nat Rev Cancer , vol.6 , pp. 369-381
    • Nakayama, K.I.1    Nakayama, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.