A small-molecule inducer of pdx1 expression identified by high-throughput screening

Chemistry and Biology

Volumn 20, Issue 12, 2013, Pages 1513-1522

  Yuan, Yuan ^a,b   Hartland, Kate ^a   Boskovic, Zarko ^a,b   Wang, Yikai ^a   Walpita, Deepika ^a   Lysy, Philippe A ^c   Zhong, Cheng ^a   Young, Damian W ^a   Kim, Young Kwon ^a   Tolliday, Nicola J ^a   Sokal, Etienne M ^c   Schreiber, Stuart L ^a,b   Wagner, Bridget K ^a  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; MESSENGER RNA; NEUROGENIN 3; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

ACINAR CELL; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CONTROLLED STUDY; EPIGENETICS; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; UPREGULATION;

MUS;

ANIMALS; CARCINOMA, DUCTAL; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HIGH-THROUGHPUT SCREENING ASSAYS; HOMEODOMAIN PROTEINS; HUMANS; MICE; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; SMALL MOLECULE LIBRARIES; TRANS-ACTIVATORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84890860572     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.10.013     Document Type: Article

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