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Volumn 24, Issue 1, 2014, Pages 32-44

Modeling heart disease in a dish: From somatic cells to disease-relevant cardiomyocytes

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; ACETYLCYSTEINE; ANTIARRHYTHMIC AGENT; ASCORBIC ACID; DANTROLENE; FLECAINIDE; GW 6471; GW 966; METOPROLOL; NADOLOL; NICORANDIL; NIFEDIPINE; PD 118057; PINACIDIL; PROPRANOLOL; RANOLAZINE; ROSCOVITINE; THAPSIGARGIN; UNCLASSIFIED DRUG;

EID: 84890794015     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2013.06.002     Document Type: Review
Times cited : (19)

References (84)
  • 2
    • 34147208940 scopus 로고    scopus 로고
    • Recessive arrhythmogenic right ventricular dysplasia due to novel cryptic splice mutation in PKP2
    • Awad M.M., Dalal D., Tichnell C., James C., Tucker A., Abraham T., et al. Recessive arrhythmogenic right ventricular dysplasia due to novel cryptic splice mutation in PKP2. Human Mutatation 2006, 27:1157.
    • (2006) Human Mutatation , vol.27 , pp. 1157
    • Awad, M.M.1    Dalal, D.2    Tichnell, C.3    James, C.4    Tucker, A.5    Abraham, T.6
  • 3
    • 33748621304 scopus 로고    scopus 로고
    • Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes
    • Beqqali A., Kloots J., Ward-van Oostwaard D., Mummery C., Passier R. Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells 2006, 24:1956-1967.
    • (2006) Stem Cells , vol.24 , pp. 1956-1967
    • Beqqali, A.1    Kloots, J.2    Ward-van Oostwaard, D.3    Mummery, C.4    Passier, R.5
  • 4
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X., Sevilla A., D'Souza S.L., Ang Y.S., Schaniel C., Lee D.F., et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010, 465:808-812.
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3    Ang, Y.S.4    Schaniel, C.5    Lee, D.F.6
  • 5
    • 79960064013 scopus 로고    scopus 로고
    • Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
    • Cermak T., Doyle E.L., Christian M., Wang L., Zhang Y., Schmidt C., et al. Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Research 2011, 39:e82.
    • (2011) Nucleic Acids Research , vol.39
    • Cermak, T.1    Doyle, E.L.2    Christian, M.3    Wang, L.4    Zhang, Y.5    Schmidt, C.6
  • 6
    • 84863213874 scopus 로고    scopus 로고
    • Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease
    • Davis R.P., Casini S., van den Berg C.W., Hoekstra M., Remme C.A., Dambrot C., et al. Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease. Circulation 2012, 125:3079-3091.
    • (2012) Circulation , vol.125 , pp. 3079-3091
    • Davis, R.P.1    Casini, S.2    van den Berg, C.W.3    Hoekstra, M.4    Remme, C.A.5    Dambrot, C.6
  • 7
    • 80052030185 scopus 로고    scopus 로고
    • Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development
    • Davis R.P., van den Berg C.W., Casini S., Braam S.R., Mummery C.L. Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development. Trends in Molecular Medicine 2011, 17:475-484.
    • (2011) Trends in Molecular Medicine , vol.17 , pp. 475-484
    • Davis, R.P.1    van den Berg, C.W.2    Casini, S.3    Braam, S.R.4    Mummery, C.L.5
  • 8
    • 77957267604 scopus 로고    scopus 로고
    • The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease
    • Delmar M., McKenna W.J. The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease. Circ Res 2010, 107:700-714.
    • (2010) Circ Res , vol.107 , pp. 700-714
    • Delmar, M.1    McKenna, W.J.2
  • 9
    • 77958568849 scopus 로고    scopus 로고
    • Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture
    • DeQuach J.A., Mezzano V., Miglani A., Lange S., Keller G.M., Sheikh F., et al. Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture. PLoS One 2010, 5:e13039.
    • (2010) PLoS One , vol.5
    • DeQuach, J.A.1    Mezzano, V.2    Miglani, A.3    Lange, S.4    Keller, G.M.5    Sheikh, F.6
  • 10
    • 80755142726 scopus 로고    scopus 로고
    • SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells
    • Dubois N.C., Craft A.M., Sharma P., Elliott D.A., Stanley E.G., Elefanty A.G., et al. SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nature Biotechnology 2011, 29:1011-1018.
    • (2011) Nature Biotechnology , vol.29 , pp. 1011-1018
    • Dubois, N.C.1    Craft, A.M.2    Sharma, P.3    Elliott, D.A.4    Stanley, E.G.5    Elefanty, A.G.6
  • 11
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert A.D., Yu J., Rose F.F., Mattis V.B., Lorson C.L., Thomson J.A., et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009, 457:277-280.
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose, F.F.3    Mattis, V.B.4    Lorson, C.L.5    Thomson, J.A.6
  • 12
    • 82355175128 scopus 로고    scopus 로고
    • NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes
    • Elliott D.A., Braam S.R., Koutsis K., Ng E.S., Jenny R., Lagerqvist E.L., et al. NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nature Methods 2011, 8:1037-1040.
    • (2011) Nature Methods , vol.8 , pp. 1037-1040
    • Elliott, D.A.1    Braam, S.R.2    Koutsis, K.3    Ng, E.S.4    Jenny, R.5    Lagerqvist, E.L.6
  • 13
    • 84863985395 scopus 로고    scopus 로고
    • Calsequestrin mutations and catecholaminergic polymorphic ventricular tachycardia
    • Faggioni M., Kryshtal D.O., Knollmann B.C. Calsequestrin mutations and catecholaminergic polymorphic ventricular tachycardia. Pediatric Cardiology 2012, 33:959-967.
    • (2012) Pediatric Cardiology , vol.33 , pp. 959-967
    • Faggioni, M.1    Kryshtal, D.O.2    Knollmann, B.C.3
  • 15
    • 80054118408 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of familial dilated cardiomyopathy
    • Fatkin D. Guidelines for the diagnosis and management of familial dilated cardiomyopathy. Heart, Lung and Circulation 2011, 20:691-693.
    • (2011) Heart, Lung and Circulation , vol.20 , pp. 691-693
    • Fatkin, D.1
  • 16
    • 84960340450 scopus 로고    scopus 로고
    • LEOPARD Syndrome
    • Seattle, University of Washington, Seattle, R.A. Pagon, M.P. Adam, T.D. Bird (Eds.)
    • Gelb B.D., Tartaglia M. LEOPARD Syndrome. GeneReviews 2007, 1993-2013. Seattle, University of Washington, Seattle. R.A. Pagon, M.P. Adam, T.D. Bird (Eds.).
    • (2007) GeneReviews , pp. 1993-2013
    • Gelb, B.D.1    Tartaglia, M.2
  • 17
    • 51449091152 scopus 로고    scopus 로고
    • Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
    • Hao J., Daleo M.A., Murphy C.K., Yu P.B., Ho J.N., Hu J., et al. Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS One 2008, 3:e2904.
    • (2008) PLoS One , vol.3
    • Hao, J.1    Daleo, M.A.2    Murphy, C.K.3    Yu, P.B.4    Ho, J.N.5    Hu, J.6
  • 21
    • 84856956771 scopus 로고    scopus 로고
    • Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
    • Israel M.A., Yuan S.H., Bardy C., Reyna S.M., Mu Y., Herrera C., et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature 2012, 482:216-220.
    • (2012) Nature , vol.482 , pp. 216-220
    • Israel, M.A.1    Yuan, S.H.2    Bardy, C.3    Reyna, S.M.4    Mu, Y.5    Herrera, C.6
  • 22
    • 84865801030 scopus 로고    scopus 로고
    • Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells
    • Itzhaki I., Maizels L., Huber I., Gepstein A., Arbel G., Caspi O., et al. Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells. Journal of the American College of Cardiology 2012, 60:990-1000.
    • (2012) Journal of the American College of Cardiology , vol.60 , pp. 990-1000
    • Itzhaki, I.1    Maizels, L.2    Huber, I.3    Gepstein, A.4    Arbel, G.5    Caspi, O.6
  • 24
    • 84858129398 scopus 로고    scopus 로고
    • Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
    • Jung C.B., Moretti A., Mederos y., Schnitzler M., Iop L., Storch U., et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Molecular Medicine 2012, 4:180-191.
    • (2012) EMBO Molecular Medicine , vol.4 , pp. 180-191
    • Jung, C.B.1    Moretti, A.2    Mederos, Y.3    Schnitzler, M.4    Iop, L.5    Storch, U.6
  • 25
    • 84876755488 scopus 로고    scopus 로고
    • Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture
    • Kamakura T., Makiyama T., Sasaki K., Yoshida Y., Wuriyanghai Y., Chen J., et al. Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture. Circulation Journal 2013, 77:1307-1314.
    • (2013) Circulation Journal , vol.77 , pp. 1307-1314
    • Kamakura, T.1    Makiyama, T.2    Sasaki, K.3    Yoshida, Y.4    Wuriyanghai, Y.5    Chen, J.6
  • 26
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • Kattman S.J., Witty A.D., Gagliardi M., Dubois N.C., Niapour M., Hotta A., et al. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 2011, 8:228-240.
    • (2011) Cell Stem Cell , vol.8 , pp. 228-240
    • Kattman, S.J.1    Witty, A.D.2    Gagliardi, M.3    Dubois, N.C.4    Niapour, M.5    Hotta, A.6
  • 27
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat I., Kenyagin-Karsenti D., Snir M., Segev H., Amit M., Gepstein A., et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. Journal of Clinical Investigation 2001, 108:407-414.
    • (2001) Journal of Clinical Investigation , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3    Segev, H.4    Amit, M.5    Gepstein, A.6
  • 28
    • 2442662544 scopus 로고    scopus 로고
    • Novel therapeutics for treatment of long-QT syndrome and torsade de pointes
    • Khan I.A., Gowda R.M. Novel therapeutics for treatment of long-QT syndrome and torsade de pointes. International Journal of Cardiology 2004, 95:1-6.
    • (2004) International Journal of Cardiology , vol.95 , pp. 1-6
    • Khan, I.A.1    Gowda, R.M.2
  • 29
    • 84874741888 scopus 로고    scopus 로고
    • Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
    • Kim C., Wong J., Wen J., Wang S., Wang C., Spiering S., et al. Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. Nature 2013, 494:105-110.
    • (2013) Nature , vol.494 , pp. 105-110
    • Kim, C.1    Wong, J.2    Wen, J.3    Wang, S.4    Wang, C.5    Spiering, S.6
  • 30
    • 78149366419 scopus 로고    scopus 로고
    • Myocardial fat at cardiac imaging: how can we differentiate pathologic from physiologic fatty infiltration?
    • Kimura F., Matsuo Y., Nakajima T., Nishikawa T., Kawamura S., Sannohe S., et al. Myocardial fat at cardiac imaging: how can we differentiate pathologic from physiologic fatty infiltration?. Radiographics 2010, 30:1587-1602.
    • (2010) Radiographics , vol.30 , pp. 1587-1602
    • Kimura, F.1    Matsuo, Y.2    Nakajima, T.3    Nishikawa, T.4    Kawamura, S.5    Sannohe, S.6
  • 33
    • 84866033059 scopus 로고    scopus 로고
    • Cell model of catecholaminergic polymorphic ventricular tachycardia reveals early and delayed afterdepolarizations
    • Kujala K., Paavola J., Lahti A., Larsson K., Pekkanen-Mattila M., Viitasalo M., et al. Cell model of catecholaminergic polymorphic ventricular tachycardia reveals early and delayed afterdepolarizations. PLoS One 2012, 7:e44660.
    • (2012) PLoS One , vol.7
    • Kujala, K.1    Paavola, J.2    Lahti, A.3    Larsson, K.4    Pekkanen-Mattila, M.5    Viitasalo, M.6
  • 35
    • 0035205336 scopus 로고    scopus 로고
    • A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel
    • Lahat H., Pras E., Olender T., Avidan N., Ben-Asher E., Man O., et al. A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel. American Journal of Human Genetics 2001, 69:1378-1384.
    • (2001) American Journal of Human Genetics , vol.69 , pp. 1378-1384
    • Lahat, H.1    Pras, E.2    Olender, T.3    Avidan, N.4    Ben-Asher, E.5    Man, O.6
  • 37
    • 0035969990 scopus 로고    scopus 로고
    • Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia
    • Laitinen P.J., Brown K.M., Piippo K., Swan H., Devaney J.M., Brahmbhatt B., et al. Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 2001, 103:485-490.
    • (2001) Circulation , vol.103 , pp. 485-490
    • Laitinen, P.J.1    Brown, K.M.2    Piippo, K.3    Swan, H.4    Devaney, J.M.5    Brahmbhatt, B.6
  • 38
    • 84861875277 scopus 로고    scopus 로고
    • PTPN11-associated mutations in the heart: has LEOPARD changed Its RASpots?
    • Lauriol J., Kontaridis M.I. PTPN11-associated mutations in the heart: has LEOPARD changed Its RASpots?. Trends in Cardiovascular Medicine 2011, 21:97-104.
    • (2011) Trends in Cardiovascular Medicine , vol.21 , pp. 97-104
    • Lauriol, J.1    Kontaridis, M.I.2
  • 39
    • 78649634707 scopus 로고    scopus 로고
    • Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies
    • Le Tourneau C., Faivre S., Laurence V., Delbaldo C., Vera K., Girre V., et al. Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies. European Journal of Cancer 2010, 46:3243-3250.
    • (2010) European Journal of Cancer , vol.46 , pp. 3243-3250
    • Le Tourneau, C.1    Faivre, S.2    Laurence, V.3    Delbaldo, C.4    Vera, K.5    Girre, V.6
  • 40
    • 84997051212 scopus 로고    scopus 로고
    • No factor left behind: generation of transgene-free induced pluripotent stem cells
    • Li M., Izpisua Belmonte J.C. No factor left behind: generation of transgene-free induced pluripotent stem cells. American Journal of Stem Cells 2012, 1:75-80.
    • (2012) American Journal of Stem Cells , vol.1 , pp. 75-80
    • Li, M.1    Izpisua Belmonte, J.C.2
  • 41
    • 77954895521 scopus 로고    scopus 로고
    • Generation of human-induced pluripotent stem cells from gut mesentery-derived cells by ectopic expression of OCT4/SOX2/NANOG
    • Li Y., Zhao H., Lan F., Lee A., Chen L., Lin C., et al. Generation of human-induced pluripotent stem cells from gut mesentery-derived cells by ectopic expression of OCT4/SOX2/NANOG. Cellular Reprogramming 2010, 12:237-247.
    • (2010) Cellular Reprogramming , vol.12 , pp. 237-247
    • Li, Y.1    Zhao, H.2    Lan, F.3    Lee, A.4    Chen, L.5    Lin, C.6
  • 43
    • 84872016692 scopus 로고    scopus 로고
    • Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/beta-catenin signaling under fully defined conditions
    • Lian X., Zhang J., Azarin S.M., Zhu K., Hazeltine L.B., Bao X., et al. Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/beta-catenin signaling under fully defined conditions. Nature Protocols 2012, 8:162-175.
    • (2012) Nature Protocols , vol.8 , pp. 162-175
    • Lian, X.1    Zhang, J.2    Azarin, S.M.3    Zhu, K.4    Hazeltine, L.B.5    Bao, X.6
  • 44
    • 67049164945 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human blood
    • Loh Y.H., Agarwal S., Park I.H., Urbach A., Huo H., Heffner G.C., et al. Generation of induced pluripotent stem cells from human blood. Blood 2009, 113:5476-5479.
    • (2009) Blood , vol.113 , pp. 5476-5479
    • Loh, Y.H.1    Agarwal, S.2    Park, I.H.3    Urbach, A.4    Huo, H.5    Heffner, G.C.6
  • 45
    • 84876522952 scopus 로고    scopus 로고
    • Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy
    • Ma D., Wei H., Lu J., Ho S., Zhang G., Sun X., et al. Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. European Heart Journal 2012, 34:1122-1133.
    • (2012) European Heart Journal , vol.34 , pp. 1122-1133
    • Ma, D.1    Wei, H.2    Lu, J.3    Ho, S.4    Zhang, G.5    Sun, X.6
  • 46
    • 78149488365 scopus 로고    scopus 로고
    • A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells
    • Marchetto M.C., Carromeu C., Acab A., Yu D., Yeo G.W., Mu Y., et al. A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells. Cell 2010, 143:527-539.
    • (2010) Cell , vol.143 , pp. 527-539
    • Marchetto, M.C.1    Carromeu, C.2    Acab, A.3    Yu, D.4    Yeo, G.W.5    Mu, Y.6
  • 48
    • 79954523845 scopus 로고    scopus 로고
    • Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
    • Matsa E., Rajamohan D., Dick E., Young L., Mellor I., Staniforth A., et al. Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation. European Heart Journal 2011, 32:952-962.
    • (2011) European Heart Journal , vol.32 , pp. 952-962
    • Matsa, E.1    Rajamohan, D.2    Dick, E.3    Young, L.4    Mellor, I.5    Staniforth, A.6
  • 49
    • 84870421675 scopus 로고    scopus 로고
    • A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions
    • Minami I., Yamada K., Otsuji T.G., Yamamoto T., Shen Y., Otsuka S., et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Reports 2012, 2:1448-1460.
    • (2012) Cell Reports , vol.2 , pp. 1448-1460
    • Minami, I.1    Yamada, K.2    Otsuji, T.G.3    Yamamoto, T.4    Shen, Y.5    Otsuka, S.6
  • 51
    • 53449095205 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium
    • John Wiley & Sons, Inc. K. Chambers (Ed.)
    • Mummery C.L., Ward D., Passier R. Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium. Current Protocols in Stem Cell Biology 2007, 2.1-2.14. John Wiley & Sons, Inc. K. Chambers (Ed.).
    • (2007) Current Protocols in Stem Cell Biology
    • Mummery, C.L.1    Ward, D.2    Passier, R.3
  • 52
    • 84864243791 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview
    • Mummery C.L., Zhang J., Ng E.S., Elliott D.A., Elefanty A.G., Kamp T.J. Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circulation Research 2012, 111:344-358.
    • (2012) Circulation Research , vol.111 , pp. 344-358
    • Mummery, C.L.1    Zhang, J.2    Ng, E.S.3    Elliott, D.A.4    Elefanty, A.G.5    Kamp, T.J.6
  • 54
    • 57649203360 scopus 로고    scopus 로고
    • Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development
    • Oishi K., Zhang H., Gault W.J., Wang C.J., Tan C.C., Kim I.K., et al. Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development. Human Molecular Genetics 2009, 18:193-201.
    • (2009) Human Molecular Genetics , vol.18 , pp. 193-201
    • Oishi, K.1    Zhang, H.2    Gault, W.J.3    Wang, C.J.4    Tan, C.C.5    Kim, I.K.6
  • 55
    • 77955290927 scopus 로고    scopus 로고
    • Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells
    • Paige S.L., Osugi T., Afanasiev O.K., Pabon L., Reinecke H., Murry C.E. Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS One 2010, 5:e11134.
    • (2010) PLoS One , vol.5
    • Paige, S.L.1    Osugi, T.2    Afanasiev, O.K.3    Pabon, L.4    Reinecke, H.5    Murry, C.E.6
  • 56
    • 84856088804 scopus 로고    scopus 로고
    • Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
    • Pasca S.P., Portmann T., Voineagu I., Yazawa M., Shcheglovitov A., Pasca A.M., et al. Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nature Medicine 2011, 17:1657-1662.
    • (2011) Nature Medicine , vol.17 , pp. 1657-1662
    • Pasca, S.P.1    Portmann, T.2    Voineagu, I.3    Yazawa, M.4    Shcheglovitov, A.5    Pasca, A.M.6
  • 57
    • 0035895322 scopus 로고    scopus 로고
    • Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia
    • Priori S.G., Napolitano C., Tiso N., Memmi M., Vignati G., Bloise R., et al. Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 2001, 103:196-200.
    • (2001) Circulation , vol.103 , pp. 196-200
    • Priori, S.G.1    Napolitano, C.2    Tiso, N.3    Memmi, M.4    Vignati, G.5    Bloise, R.6
  • 58
    • 67649871391 scopus 로고    scopus 로고
    • Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy
    • Remme C.A., Scicluna B.P., Verkerk A.O., Amin A.S., van Brunschot S., Beekman L., et al. Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy. Circ Res 2009, 104:1283-1292.
    • (2009) Circ Res , vol.104 , pp. 1283-1292
    • Remme, C.A.1    Scicluna, B.P.2    Verkerk, A.O.3    Amin, A.S.4    van Brunschot, S.5    Beekman, L.6
  • 59
    • 38049146378 scopus 로고    scopus 로고
    • Clinical practice. Long-QT syndrome
    • Roden D.M. Clinical practice. Long-QT syndrome. New England Journal of Medicine 2008, 358:169-176.
    • (2008) New England Journal of Medicine , vol.358 , pp. 169-176
    • Roden, D.M.1
  • 60
    • 80054008664 scopus 로고    scopus 로고
    • Arrhythmogenic cardiomyopathy: advances in diagnosis and disease pathogenesis
    • Saffitz J.E. Arrhythmogenic cardiomyopathy: advances in diagnosis and disease pathogenesis. Circulation 2011, 124:e390-e392.
    • (2011) Circulation , vol.124
    • Saffitz, J.E.1
  • 62
    • 34247280500 scopus 로고    scopus 로고
    • Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression
    • Sen-Chowdhry S., Syrris P., Ward D., Asimaki A., Sevdalis E., McKenna W.J. Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression. Circulation 2007, 115:1710-1720.
    • (2007) Circulation , vol.115 , pp. 1710-1720
    • Sen-Chowdhry, S.1    Syrris, P.2    Ward, D.3    Asimaki, A.4    Sevdalis, E.5    McKenna, W.J.6
  • 63
    • 74549126556 scopus 로고    scopus 로고
    • Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives
    • Shah R.R. Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives. British Journal of Pharmacology 2010, 159:58-69.
    • (2010) British Journal of Pharmacology , vol.159 , pp. 58-69
    • Shah, R.R.1
  • 65
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F., Hockemeyer D., Beard C., Gao Q., Bell G.W., Cook E.G., et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009, 136:964-977.
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3    Gao, Q.4    Bell, G.W.5    Cook, E.G.6
  • 66
    • 79960833952 scopus 로고    scopus 로고
    • Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
    • Soldner F., Laganiere J., Cheng A.W., Hockemeyer D., Gao Q., Alagappan R., et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 2011, 146:318-331.
    • (2011) Cell , vol.146 , pp. 318-331
    • Soldner, F.1    Laganiere, J.2    Cheng, A.W.3    Hockemeyer, D.4    Gao, Q.5    Alagappan, R.6
  • 67
    • 5344223383 scopus 로고    scopus 로고
    • Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
    • Splawski I., Timothy K.W., Sharpe L.M., Decher N., Kumar P., Bloise R., et al. Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell 2004, 119:19-31.
    • (2004) Cell , vol.119 , pp. 19-31
    • Splawski, I.1    Timothy, K.W.2    Sharpe, L.M.3    Decher, N.4    Kumar, P.5    Bloise, R.6
  • 70
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 71
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 74
    • 84872048038 scopus 로고    scopus 로고
    • Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
    • Tohyama S., Hattori F., Sano M., Hishiki T., Nagahata Y., Matsuura T., et al. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell 2013, 12:127-137.
    • (2013) Cell Stem Cell , vol.12 , pp. 127-137
    • Tohyama, S.1    Hattori, F.2    Sano, M.3    Hishiki, T.4    Nagahata, Y.5    Matsuura, T.6
  • 75
    • 18944373328 scopus 로고    scopus 로고
    • Highly efficient endogenous human gene correction using designed zinc-finger nucleases
    • Urnov F.D., Miller J.C., Lee Y.L., Beausejour C.M., Rock J.M., Augustus S., et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 2005, 435:646-651.
    • (2005) Nature , vol.435 , pp. 646-651
    • Urnov, F.D.1    Miller, J.C.2    Lee, Y.L.3    Beausejour, C.M.4    Rock, J.M.5    Augustus, S.6
  • 77
    • 25144503454 scopus 로고    scopus 로고
    • Genetics of cardiac arrhythmias
    • Wilde A.A., Bezzina C.R. Genetics of cardiac arrhythmias. Heart 2005, 91:1352-1358.
    • (2005) Heart , vol.91 , pp. 1352-1358
    • Wilde, A.A.1    Bezzina, C.R.2
  • 78
    • 80051796581 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm
    • Willems E., Spiering S., Davidovics H., Lanier M., Xia Z., Dawson M., et al. Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circulation Research 2011, 109:360-364.
    • (2011) Circulation Research , vol.109 , pp. 360-364
    • Willems, E.1    Spiering, S.2    Davidovics, H.3    Lanier, M.4    Xia, Z.5    Dawson, M.6
  • 80
    • 77950623520 scopus 로고    scopus 로고
    • IPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin
    • Yan X., Qin H., Qu C., Tuan R.S., Shi S., Huang G.T. iPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin. Stem Cells and Development 2010, 19:469-480.
    • (2010) Stem Cells and Development , vol.19 , pp. 469-480
    • Yan, X.1    Qin, H.2    Qu, C.3    Tuan, R.S.4    Shi, S.5    Huang, G.T.6
  • 81
    • 79952438377 scopus 로고    scopus 로고
    • Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
    • Yazawa M., Hsueh B., Jia X., Pasca A.M., Bernstein J.A., Hallmayer J., et al. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 2011, 471:230-234.
    • (2011) Nature , vol.471 , pp. 230-234
    • Yazawa, M.1    Hsueh, B.2    Jia, X.3    Pasca, A.M.4    Bernstein, J.A.5    Hallmayer, J.6
  • 83
    • 84867746044 scopus 로고    scopus 로고
    • Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method
    • Zhang J., Klos M., Wilson G.F., Herman A.M., Lian X., Raval K.K., et al. Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circulation Research 2012, 111:1125-1136.
    • (2012) Circulation Research , vol.111 , pp. 1125-1136
    • Zhang, J.1    Klos, M.2    Wilson, G.F.3    Herman, A.M.4    Lian, X.5    Raval, K.K.6
  • 84
    • 80054762880 scopus 로고    scopus 로고
    • Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells
    • Zhu W.Z., Van Biber B., Laflamme M.A. Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells. Methods in Molecular Biology 2011, 767:419-431.
    • (2011) Methods in Molecular Biology , vol.767 , pp. 419-431
    • Zhu, W.Z.1    Van Biber, B.2    Laflamme, M.A.3


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