Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism

Mechanisms of Ageing and Development

Volumn 133, Issue 5, 2012, Pages 368-371

  Lesniewski, Lisa A ^a,b,c   Zigler, Melanie C ^a   Durrant, Jessica R ^a   Donato, Anthony J ^a,b,c   Seals, Douglas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Endothelium dependent dilation; Endothelium dependent hyperpolarizing factor; Prostaglandins

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYLCHOLINE; ADENOSINE MONOPHOSPHATE PROTEIN ACTIVATED PROTEIN KINASE; ADENOSINE PHOSPHATE; HYDROGEN PEROXIDE; NITRIC OXIDE; PROSTAGLANDIN; TEMPOL; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; HYPERPOLARIZATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AGING; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; CYCLIC N-OXIDES; ENDOTHELIUM, VASCULAR; MICE; NITRIC OXIDE; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; SPIN LABELS; SUPEROXIDES; VASODILATION; VASODILATOR AGENTS;

MUS;

EID: 84861235129     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.03.011     Document Type: Article

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