Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat

Free Radical Research

Volumn 45, Issue 7, 2011, Pages 788-795

  Lakshmanan, Arun Prasath ^a   Watanabe, Kenichi ^a   Thandavarayan, Rajarajan A ^a   Sari, Flori R ^a   Meilei, Harima ^a   Soetikno, Vivian ^a   Arumugam, Somasundaram ^a   Giridharan, Vijayasree V ^a   Suzuki, Kenji ^b   Kodama, Makoto ^c  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b Department of Gastroenterology and Hepatology ^*  (Japan)

^c NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

AMPK; apoptosis; Curcumin; diabetic encephalopathy; oxidative stress

Indexed keywords

ADIPONECTIN RECEPTOR 1; CASPASE 12; CURCUMIN; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; NEUROTROPHIN 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; DIABETIC ENCEPHALOPATHY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SUBUNIT; GLUCONEOGENESIS; HYPERGLYCEMIA; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; STREPTOZOCIN DIABETES;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BRAIN DISEASES; CEREBRUM; CURCUMIN; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; ENZYME ACTIVATION; HYPERGLYCEMIA; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; STREPTOZOCIN;

RATTUS;

EID: 79957910169     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.579121     Document Type: Article

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