The effect of deposition Se on the mRNA expression levels of GPxs in goats from a Se-enriched County of China

Biological Trace Element Research

Volumn 156, Issue 1-3, 2013, Pages 111-123

  Zhang, Lei ^a   Zhou, Zhan Qin ^a   Li, Guang ^a   Fu, Ming Zhe ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Goats; GPx; mRNA expression; Selenium; Ziyang County

Indexed keywords

GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; GLUTATHIONE PEROXIDASE 3; MESSENGER RNA; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; SELENIUM;

ANIMAL EXPERIMENT; ARTICLE; BICEPS FEMORIS MUSCLE LEVEL; CHINA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEMOGRAPHY; FLUORESCENCE SPECTROSCOPY; GENE EXPRESSION; GENE SEQUENCE; HEART LEVEL; KIDNEY LEVEL; LIVER LEVEL; LONGISSIMUS MUSCLE LEVEL; LUNG LEVEL; MUSCLE LEVEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; SELENIUM BLOOD LEVEL; SPLEEN LEVEL; TISSUE LEVEL;

ANIMALS; CHINA; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE PEROXIDASE; GOATS; MALE; ORGAN SPECIFICITY; RNA, MESSENGER; SELENIUM;

EID: 84890661584     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-013-9830-5     Document Type: Article

References (129)

1. Liu K, Zhao Y, Chen F, Gu Z, Bu G (2011) Enhanced glutathione peroxidases (GPx) activity in young barley seedlings enriched with selenium. Afr J Biotechnol 10(55):11483-11487
2. Zhan X, Qie Y, Wang M, Li X, Zhao R (2011) Selenomethionine: an effective selenium source for sow to improve Se distribution, antioxidant status, and growth performance of pig offspring. Biol Trace Elem Res 142(3):481-491
3. Hoefig CS, Renko K, Koehrle J, Birringer M, Schomburg L (2011) Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. J Nutr Biochem 22(10):945-955
4. Encinar JR, Sliwka KM, Polatajko A, Vacchina V, Szpunar J (2003) Methodological advances for selenium speciation analysis in yeast. Anal Chim Acta 500(1-2):171-183
5. Tapiero H, Townsend D, Tew K (2003) The antioxidant role of selenium and seleno-compounds. Biomedicine Pharmacother 57(3):134-144
6. Spallholz JE, Hoffman DJ (2002) Selenium toxicity cause and effects in aquatic birds. Aquat Toxicol 57(1-2):27-37
7. Hoffmann PR, Berry MJ (2008) The influence of selenium on immune responses. Mol Nutr Food Res 52(11):1273-1280
8. Zhang Q, Chen L, Guo K, Zheng L, Liu B, Yu W, Guo C, Liu Z, Chen Y, Tang Z (2013) Effects of different selenium levels on gene expression of a subset of selenoproteins and antioxidative capacity in mice. Biol Trace Elem Res 154(2):255-261
9. Ou BR, Jiang MJ, Lin CH, Liang YC, Lee KJ, Yeh JY (2011) Characterization and expression of chicken selenoprotein W. Biometals 24(2):323-333
10. Ruan H, Zhang Z, Wu Q, Yao H, Li J, Li S, Xu S (2012) Selenium regulates gene expression of selenoprotein W in chicken skeletal muscle system. Biol Trace Elem Res 145(1):59-65
11. Jerome MA, Bera S, Rachidi W, Gann PH, Diamond AM (2013) The effects of selenium and the GPx-1 selenoprotein on the phosphorylation of H2AX. Biochim Biophys Acta Gen Subj 1830(6):3399-3406
12. Doni M, Falanga A, Delaini F, Vicenzi E, Tomasiak M, Donati M (1984) The effect of vitamin E or selenium on the oxidant-antioxidant balance in rats. Br J Exp Pathol 65(1):75-80
13. Awadeh FT, Kincaid RL, Johnson KA (1998) Effect of level and source of dietary selenium on concentrations of thyroid hormones and immunoglobulins in beef cows and calves. J Anim Sci 76(4):1204-1215
14. Muth O, Oldfield J, Remmert L, Schubert JR (1958) Effects of selenium and vitamin E on white muscle disease. Science 128:1090
15. Rotruck J, Pope A, Ganther H, Swanson A, Hafeman DG, Hoekstra W (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179(4073):588-590
16. Zhang JX, Wang Q, Xun WJ, Ren YS, Yue WB, Zhang CX (2011) GPXs family genes in different tissues and goat testis express characteristics of different development periods study. J Anim Husb Vet 42(5):650-657
17. Liu CX, Li SC, Chen J, Liu MF, Yan LJ, Wang YR, Zhang H, Pei JR, Zhou LW, Hou J (2011) Selenium and protein and selenium rats myocardial GPX1, GPX4 expression and translation. Chin J Prev Cure Endemic Dis 26(1):4-6
18. Forgione MA, Weiss N, Heydrick S, Cap A, Klings ES, Bierl C, Eberhardt RT, Farber HW, Loscalzo J (2002) Cellular glutathione peroxidase deficiency and endothelial dysfunction. Am J Physiol Heart Circ Physiol 282(4):1255-1261
19. Esworthy RS, Swiderek KM, Ho YS, Chu FF (1998) Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine. Biochim Biophys Acta (BBA) Gen Sub 1381(2):213-226
20. Florian S, Wingler K, Schmehl K, Jacobasch G, Kreuzer OJ, Meyerhof W, Brigelius FR (2001) Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue. Free Radic Res 35(6):655-663
21. Komatsu H, Okayasu I, Mitomi H, Imai H, Nakagawa Y, Obata F (2001) Immunohistochemical detection of human gastrointestinal glutathione peroxidase in normal tissues and cultured cells with novel mouse monoclonal antibodies. J Histochem Cytochem 49(6):759-766
22. Chu FF, Esworthy RS, Doroshow JH (2004) Role of Se-dependent glutathione peroxidases in gastrointestinal inflammation and cancer. Free Radic Biol Med 36(12):1481-1495
23. Whitin JC, Tham DM, Bhamre S, Ornt DB, Scandling JD, Tune BM, Salvatierra O, Avissar N, Cohen HJ (1998) Plasma glutathione peroxidase and its relationship to renal proximal tubule function. Mol Genet Metab 65(3):238-245
24. Chabory E, Damon C, Lenoir A, Henry BJ, Vernet P, Cadet R, Saez F, Drevet J (2010) Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity. J Anim Sci 88(4):1321-1331
25. Gromer S, Eubel J, Lee B, Jacob J (2005) Human selenoproteins at a glance. Cell Mol Life Sci 62(21):2414-2437
26. Behne D, Kyriakopoulos A (2001) Mammalian selenium-containing proteins. Annu Rev Nutr 21(1):453-473
27. Chu FF, Esworthy RS, Doroshow J, Doan K, Liu XF (1992) Expression of plasma glutathione peroxidase in human liver in addition to kidney, heart, lung, and breast in humans and rodents. Blood 79(12):3233-3238
28. Tham DM, Whitin JC, Kim KK, Zhu SX, Cohen HJ (1998) Expression of extracellular glutathione peroxidase in human and mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol 275(6):1463-1471
29. Ursini F, Maiorino M, Valente M, Ferri L, Gregolin C (1982) Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides. Biophys Acta (BBA) Lipids Lipid Metab 710(2):197-211
30. Chen ZH, Ren HE, Xu LM (2013) Effect of Ligustrum lucidum on muscle antioxidant capacity and GPx4 gene expression of AA Broilers. Chin J Anim Sci 49(5):53-56
31. Gatellier P, Mercier Y, Renerre M (2004) Effect of diet finishing mode (pasture or mixed diet) on antioxidant status of Charolais bovine meat. Meat Sci 67(3):385-394
32. Conrad M, Schneider M, Seiler A, Bornkamm GW (2007) Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals. Biol Chem 388(10):1019-1025
33. Agbor GA, Vinson JA, Patel S, Patel K, Scarpati J, Shiner D, Wardrop F, Tompkins TA (2007) Effect of selenium and glutathione enriched yeast supplementation on a combined atherosclerosis and diabetes hamster model. J Agric Food Chem 55(21):8731-8736
34. Hoffmann PR, Höge SC, Li PA, Hoffmann FW, Hashimoto AC, Berry MJ (2007) The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply. Nucleic Acids Res 35(12):3963-3973
35. Pilarczyk B, Drozd R, Pilarczyk R, Tomza-Marciniak A, Jankowiak D, Hendzel D, Kuba J, Kowalska J (2011) Glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to hepatic selenium concentrations, sex, body weight and season of the year. Biol Trace Elem Res 144(1):560-569
36. Dȩbski B, Zachara B, Wa̧sowicz W (2001) An attempt to evaluate the level of selenium in Poland and its influence on the healthiness of people and animals. Folia Univ Agric Stetin Zootech 224(42):31-38
37. Youssef MA, Elkhodery SA, Ibrahim HMM (2013) Effect of selenium and vitamin C on clinical outcomes, trace element status, and antioxidant enzyme activity in horses with acute and chronic lower airway disease. Biol Trace Elem Res 152(3):333-342
38. Pilarczyk B, Tomza Marciniak A, Mituniewicz Małek A, Wieczorek Da̧browska M, Pilarczyk R, Wójcik J, Balicka Ramisz A, Ba̧kowska M, Dmytrów I (2010) Selenium content in selected products of animal origin and estimation of the degree of cover daily Se requirement in Poland. Int J Food Sci Technol 45(1):186-191
39. Thiry C, Schneider YJ, Pussemier L, De Temmerman L, Ruttens A (2013) Selenium bioaccessibility and bioavailability in Se-enriched food supplements. Biol Trace Elem Res 152(1):152-160
40. Luo PL, Zhang P, He J, Mao XB, Yu B, Chen DW (2012) Different selenium sources and levels affect growth performance, serum antioxidant ability and tissue selenium retention in Wistar Rats. Chin J Anim Nutr 24(7):1311-1319
41. Zheng LY, Zhang Q, Liu BT, Guo k, Yu WL, Liu ZW (2013) Effect of different dietary selenium concentration on mRNA levels of some selenoprotein in mice liver and testis. China Anim Husb Vet Med 40(3):38-42
42. Zhao CY, Ren JH, Xue CG (1993) Selenium in soils of selenium-rich areas in Ziyang country. Acta Pedologica Sin 30(3):253-259
43. Kieliszek M, Błazejak S (2013) Selenium: significance, and outlook for supplementation. Nutrition 5(29):713-718
44. Luo X, Wei H, Yang C, Xing J, Liu X, Qiao C, Feng Y, Liu J, Liu Y, Wu Q (1985) Bioavailability of selenium to residents in a low-selenium area of China. Am J Clin Nutr 42(3):439-448
45. Clark LC, Combs GF, Turnbull BW, Slate EH, Chalker DK, Chow J, Davis LS, Glover RA, Graham GF, Gross EG (1996) Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. J Am Med Assoc 276(24):1957-1963
46. Fordyce F, Guangdi Z, Green K, Xinping L (2000) Soil, grain and water chemistry in relation to human selenium-responsive diseases in Enshi District, China. Appl Geochem 15(1):117-132
47. Hawkes WC, Kelley DS, Taylor PC (2001) The effects of dietary selenium on the immune system in healthy men. Biol Trace Elem Res 81(3):189-213
48. Humann-Ziehank E, Renko K, Mueller AS, Roehrig P, Wolfsen J, Ganter M (2013) Comparing functional metabolic effects of marginal and sufficient selenium supply in sheep. J Trace Elem Med Biol. doi: 10.1016/j.jtemb, 2013.03.003(Published online)
49. Jianhua H, Ohtsuka A, Hayashi K (2000) Selenium influences growth via thyroid hormone status in broiler chickens. Br J Nutr 84(5):727-732
50. Qin S, Gao J, Huang K (2007) Effects of different selenium sources on tissue selenium concentrations, blood GSH-Px activities and plasma interleukin levels in finishing lambs. Biol Trace Elem Res 116(1):91-102
51. Davis P, McDowell L, Wilkinson N, Buergelt C, Van Alstyne R, Weldon R, Marshall T, Matsuda-Fugisaki E (2008) Comparative effects of various dietary levels of Se as sodium selenite or Se yeast on blood, wool, and tissue Se concentrations of wether sheep. Small Rumin Res 74(1):149-158
52. Juniper D, Bertin G (2013) Effects of dietary selenium supplementation on tissue selenium distribution and glutathione peroxidase activity in Chinese ring necked pheasants. Animal 7(4):562-570
53. Pan CL (2008) The application of organic selenium source in hen production and research for the mechanism. Doctoral dissertation, Nanjing Agrieultural University
54. Echevarria M, Henry P, Ammerman C, Rao P (1988) Effects of time and dietary selenium concentration as sodium selenite on tissue selenium uptake by sheep. J Anim Sci 66(9):2299-2305
55. Tarla F, Henry P, Ammerman C, Rao P, Miles R (1991) Effect of time and sex on tissue selenium concentrations in chicks fed practical diets supplemented with sodium selenite or calcium selenite. Biol Trace Elem Res 31(1):11-20
56. Bermano G, Nicol F, Dyer J, Sunde R, Beckett G, Arthur J, Hesketh J (1995) Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats. Biochem J 311:425-430
57. Flohe L (2007) Selenium in mammalian spermiogenesis. Biol Chem 388(10):987-995
58. Schomburg L, Schweizer U (2009) Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium. Biochim Biophysi Acta (BBA) Gen Subj 1790(11):1453-1462
59. Tato RR, Cárdenas VE, Herrero HE (1994) Selenium: the physiopathological and clinical implications. An Med Interna 11(9):457-463
60. Baek IJ, Seo DS, Yon JM, Lee SR, Jin Y, Nahm SS, Jeong JH, Choo YK, Kang JK, Lee BJ (2007) Tissue expression and cellular localization of phospholipid hydroperoxide glutathione peroxidase (PHGPx) mRNA in male mice. J Mol Histol 38(3):237-244
61. Auger J, Yang W, Arnault I, Pannier F, Potin Gautier M (2004) High-performance liquid chromatographic-inductively coupled plasma mass spectrometric evidence for Se-"alliins" in garlic and onion grown in Se-rich soil. J Chromatogr A 1032:103-107
62. Xie M, von Bohlen A, Klockenkämper R, Jian X, Günther K (1998) Multi-element analysis of Chinese tea (Camellia sinensis) by total-reflection X-ray fluorescence. Z Leb Unters Forsch A 207(1):31-38
63. Lei XG, Evenson JK, Thompson KM, Sunde RA (1995) Glutathione-peroxidase and phospholipid hydroperoxide glutathione-peroxidase are differentially regulated in rats by dietary seleniun. J Nutr 125(6):1438-1446
64. Brigelius FR (2006) Glutathione peroxidases and redox-regulated transcription factors. Biol Chem 387(10-11):1329-1335
65. Modrick ML, Didion SP, Lynch CM, Dayal S, Lentz SR, Faraci FM (2009) Role of hydrogen peroxide and the impact of glutathione peroxidase-1 in regulation of cerebral vascular tone. J Cereb Blood Flow Metab 29(6):1130-1137
66. Chrissobolis S, Faraci FM (2008) The role of oxidative stress and NADPH oxidase in cerebrovascular disease. Trends Mol Med 14(11):495-502
67. Thu VT, Kim HK, Ha SH, Yoo JY, Park WS, Kim N, Oh GT, Han J (2010) Glutathione peroxidase 1 protects mitochondria against hypoxia/reoxygenation damage in mouse hearts. Pflügers Archiv Eur J Physiol 460(1):55-68
68. Sunde RA, Raines AM, Barnes KM, Evenson JK (2009) Selenium status highly regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome. Biosci Rep 29(5):329-338
69. Fukuhara R, Kageyama T (2003) Tissue distribution, molecular cloning, and gene expression of cytosolic glutathione peroxidase in Japanese monkey. Zool Sci 20(7):861-868
70. Fukuhara R, Kageyama T (2005) Structure, gene expression, and evolution of primate glutathione peroxidases. Comp Biochem Physiol B Biochem Mol Biol 141(4):428-436
71. Munz B, Frank S, Hubner G, Olsen E, Werner S (1997) A novel type of glutathione peroxidase: expression and regulation during wound repair. Biochem J 326:579-585
72. Himeno S, Takekawa A, Imura N (1993) Species difference in hydroperoxide-scavenging enzymes with special reference to glutathione peroxidase in guinea-pigs. Comp Biochem Physiology Part B Comp Biochem 104(1):27-31
73. Evenson JK, Wheeler AD, Blake SM, Sunde RA (2004) Selenoprotein mRNA is expressed in blood at levels comparable to major tissues in rats. J Nutr 134(10):2640-2645
74. Jiang L, Wu ZM, Lu AX (2012) Effects of organic selenium sources on growth performance and antioxidant capability in young rex rabbits. Chin J Anim Sci 48(17):27-31
75. Hemingway R (2003) The influences of dietary intakes and supplementation with selenium and vitamin E on reproduction diseases and reproductive efficiency in cattle and sheep. Vet Res Commun 27(2):159-174
76. 1,2,3. Nutr Requir Interact 126(9):2260-2267
77. Barnes KM, Evenson JK, Raines AM, Sunde RA (2009) Transcript analysis of the selenoproteome indicates that dietary selenium requirements of rats based on selenium-regulated selenoprotein mRNA levels are uniformly less than those based on glutathione peroxidase activity. J Nutr 139(2):199-206
78. Hill KE, Reid Lyons P, Burk RF (1992) Differential regulation of rat liver selenoprotein mRNAs in selenium deficiency. Biochem Biophys Res Commun 185(1):260-263
79. Lum GE, Rowntree JE, Bondioli KR, Southern LL, Williams CC (2009) The influence of dietary selenium on common indicators of selenium status and liver glutathione peroxidase-1 mRNA. J Anim Sci. doi: 10.2527/jas, 2008-1417(Published online)
80. Moriarty PM, Reddy CC, Maquat LE (1998) Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA. Mol Cell Biol 18(5):2932-2939
81. Banning A, Florian S, Deubel S, Thalmann S, Müller-Schmehl K, Jacobasch G, Brigelius-Flohé R (2008) GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells. Antioxid Redox Signal 10(9):1491-1500
82. Brigelius-Flohé R, Kipp A (2009) Glutathione peroxidases in different stages of carcinogenesis. BiochimBiophys Acta (BBA) Gen Subj 1790(11):1555-1568
83. Al-Taie OH, Uceyler N, Eubner U, Jakob F, Mork H, Scheurlen M, Brigelius-Flohe R, Schottker K, Abel J, Thalheimer A (2004) Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis. Nutr Cancer 48(1):6-14
84. Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T (2007) Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens. Cancer Res 67(23):11353-11358
85. Banning A, Kipp A, Schmitmeier S, Löwinger M, Florian S, Krehl S, Thalmann S, Thierbach R, Steinberg P, Brigelius-Flohé R (2008) Glutathione peroxidase 2 inhibits cyclooxygenase-2-mediated migration and invasion of HT-29 adenocarcinoma cells but supports their growth as tumors in nude mice. Cancer Res 68(23):9746-9753
86. Walshe J, Serewko-Auret MM, Teakle N, Cameron S, Minto K, Smith L, Burcham PC, Russell T, Strutton G, Griffin A (2007) Inactivation of glutathione peroxidase activity contributes to UV-induced squamous cell carcinoma formation. Cancer Res 67(10):4751-4758
87. Chu FF, Esworthy RS, Chu PG, Longmate JA, Huycke MM, Wilczynski S, Doroshow JH (2004) Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes. Cancer Res 64(3):962-968
88. Esworthy RS, Yang L, Frankel PH, Chu FF (2005) Epithelium-specific glutathione peroxidase, Gpx2, is involved in the prevention of intestinal inflammation in selenium-deficient mice. J Nutr 135(4):740-745
89. Rayman MP (2005) Selenium in cancer prevention: a review of the evidence and mechanism of action. Presented at Proceedings-nutrition Society of London, Cambridge Univ Press: 527
90. Pagmantidis V, Bermano G, Villette S, Broom I, Arthur J, Hesketh J (2005) Effects of Se-depletion on glutathione peroxidase and selenoprotein W gene expression in the colon. Febs Lett 579(3):792-796
91. Wingler K, Bocher M, Flohe L, Kollmus H, Brigelius-Flohe R (1999) mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins. Eur J Biochem 259(1-2):149-157
92. Brigelius FR, Müller C, Menard J, Florian S, Schmehl K, Wingler K (2001) Functions of GI-GPx: lessons from selenium-dependent expression and intracellular localization. Biofactors 14(1):101-106
93. Yu Y, Lv L, Zhang YY, Luo XG (2007) Regulation of selenium on gene expression and enzyme activity in selenoproteins gluthathione peroxidas. Chin J Anim Nutr 19:469-474
94. Mistry H, Kurlak L, Williams P, Ramsay M, Symonds M, Broughton Pipkin F (2010) Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy. Placenta 31(5):401-408
95. Comhair SA, Erzurum SC (2005) The regulation and role of extracellular glutathione peroxidase. Antioxid Redox Signal 7(1-2):72-79
96. Falck E, Karlsson S, Carlsson J, Helenius G, Karlsson M, Klinga LK (2010) Loss of glutathione peroxidase 3 expression is correlated with epigenetic mechanisms in endometrial adenocarcinoma. Cancer Cell Int 10(46):1-9
97. Taulli R, Scuoppo C, Bersani F, Accornero P, Forni PE, Miretti S, Grinza A, Allegra P, Schmitt NM, Crepaldi T (2006) Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma. Cancer Res 66(9):4742-4749
98. Lutterbach B, Zeng Q, Davis LJ, Hatch H, Hang G, Kohl NE, Gibbs JB, Pan BS (2007) Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. Cancer Res 67(5):2081-2088
99. Wang R, Ferrell LD, Faouzi S, Maher JJ, Bishop JM (2001) Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice. J Cell Biol 153(5):1023-1034
100. Schmidt L, Junker K, Nakaigawa N, Kinjerski T, Weirich G, Miller M, Lubensky I, Neumann HP, Brauch H, Decker J (1999) Novel mutations of the MET proto-oncogene in papillary renal carcinomas. Oncogene 18(14):2343-2350
101. Avissar N, Slemmon JR, Palmer IS, Cohen HJ (1991) Partial sequence of human plasma glutathione peroxidase and immunologic identification of milk glutathione peroxidase as the plasma enzyme. J Nutr 121(8):1243-1249
102. Avissar N, Eisenmann C, Breen JG, Horowitz S, Miller RK, Cohen HJ (1994) Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation. Am J Physiol Endocrinol Metab 267(1):68-76
103. Comhair SA, Bhathena PR, Farver C, Thunnissen FB, Eraurum SC (2001) Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells. FASEB Journal 15(1):70-78
104. Maeda K, Okubo K, Shimomura I, Mizuno K, Matsuzawa Y, Matsubara K (1997) Analysis of an expression profile of genes in the human adipose tissue. Gene 190(2):227-235
105. Whitin JC, Bhamre S, Tham DM, Cohen HJ (2002) Extracellular glutathione peroxidase is secreted basolaterally by human renal proximal tubule cells. Am J Physiol Ren Physiol 283(1):20-28
106. Avissar N, Kerl E, Baker S, Cohen H (1994) Extracellular glutathione peroxidase mRNA and protein in human cell lines. Arch Biochem Biophys 309(2):239-246
107. Martín Alonso JM, Ghosh S, Coca PM (1993) Cloning of the bovine plasma selenium-dependent glutathione peroxidase (GPx) cDNA from the ocular ciliary epithelium: expression of the plasma and cellular forms within the mammalian eye. J Biochem 114(2):284-291
108. Yoshimura S, Watanabe K, Suemizu H, Onozawa T, Mizoguchi J, Tsuda K, Hatta H, Moriuchi T (1991) Tissue specific expression of the plasma glutathione peroxidase gene in rat kidney. J Biochem 109(6):918-923
109. Kingsley PD, Whitin JC, Cohen HJ, Palis J (1998) Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin. Mol Reprod Dev 49(4):343-355
110. Maser RL, Magenheimer BS, Calvet JP (1994) Mouse plasma glutathione peroxidase, cDNA sequence analysis and renal proximal tubular expression and secretion. J Biol Chem 269(43):27066-27073
111. Nakane T, Asayama K, Kodera K, Hayashibe H, Uchida N, Nakazawa S (1998) Effect of selenium deficiency on cellular and extracellular glutathione peroxidases: Immunochemical detection and mRNA analysis in rat kidney and serum. Free Radic Biol Med 25(4-5):504-511
112. Ottaviano FG, Tang SS, Handy DE, Loscalzo J (2009) Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. Mol Cell Biochem 327(1-2):111-126
113. Raines AM, Sunde RA (2011) Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents. BMC Genomics 12:26. doi: 10.1186/1471-2164-12-26, Published online
114. Chavatte L, Brown BA, Driscoll DM (2005) Ribosomal protein L30 is a component of the UGA-selenocysteine recoding machinery in eukaryotes. Nat Struct Mol Biol 12(5):408-416
115. Shen QC, Fan L, Newburger PE (2006) Nuclease sensitive element binding protein 1 associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. J Cell Physiol 207(3):775-783
116. Bierl C, Voetsch B, Jin RC, Handy DE, Loscalzo J (2004) Determinants of human plasma glutathione peroxidase (GPx-3) expression. J Biol Chem 279(26):26839-26845
117. Driscoll DM, Copeland PR (2003) Mechanism and regulation of selenoprotein synthesis. Annu Rev Nutr 23:17-40
118. Arthur J (2001) The glutathione peroxidases. Cell Mol Life Sci 57(13-14):1825-1835
119. Bellinger F, Raman A, Reeves M, Berry M (2009) Regulation and function of selenoproteins in human disease. Biochem J 422:11-22
120. Brigelius-Flohé R (1999) Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med 27(9):951-965
121. Imai H, Nakagawa Y (2003) Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med 34(2):145-169
122. Liang H, Remmen HV, Frohlich V, Lechleiter J, Richardson A, Ran Q (2007) Gpx4 protects mitochondrial ATP generation against oxidative damage. Biochem Biophys Res Commun 356(4):893-898
123. Cole EP, Swan D, Shanley D, Hesketh J (2012) Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells. Free Radic Biol Med 53(3):488-497
124. Godeas C, Tramer F, Micali F, Roveri A, Maiorino M, Nisii C, Sandri G, Panfili E (1996) Phospholipid hydroperoxide glutathione peroxidase (PHGPx) in rat testis nuclei is bound to chromatin. Biochem Mol Med 59(2):118-124
125. Roveri A, Casasco A, Maiorino M, Dalan P, Calligaro A, Ursini F (1992) Phospholipid hydroperoxide glutathione peroxidase of rat testis. Gonadotropin dependence and immunocytochemical identification. J Biol Chem 267(9):6142-6146
126. Chen W, Du JF, Cui QM, Cheng QM, Hu YX, Yang L, Zeng YQ (2011) Tissue expression profiles of GPx4 gene in Laiwu pigs. J Shandong Agric Univ (Nat Sci) 42(3):433-437
127. Sunde RA, Hadley KB (2010) Phospholipid hydroperoxide glutathione peroxidase (Gpx4) is highly regulated in male turkey poults and can be used to determine dietary selenium requirements. Exp Biol Med 235(1):23-31
128. Zoidis E, Pappas A, Georgiou C, Komaitis E, Feggeros K (2010) Selenium affects the expression of GPx4 and catalase in the liver of chicken. Comp Biochem Physiol B Biochem Mol Biol 155(3):294-300
129. Yin J, Yang G, He T, Luo YH, Fang RJ (2012) Advances in Se- enriched yeast on poultry nutrition. Chin J Anim Sci 48(1):63-66