Functions of GI-GPx: Lessons from selenium-dependent expression and intracellular localization

BioFactors

Volumn 14, Issue 1-4, 2001, Pages 101-106

  Brigelius Flohe R ^a   Muller C ^a   Menard, J ^a   Florian, S ^a   Schmehl, K ^a   Wingler, K ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

Biological role; GI GPx; Immune histochemistry; Selenium responsiveness

Indexed keywords

GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; PEROXIDASE; SELENIUM; SELENOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SELENIUM DEFICIENCY; TRANSCRIPTION REGULATION; TUMOR CELL LINE;

ANIMALIA; MAMMALIA;

EID: 0034856806     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520140114     Document Type: Conference Paper

References (20)

1. The diversity of glutathione peroxidases
2. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI
3. Selenium-dependent glutathione peroxidase-G1 is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine
4. Tissue-specific functions of individual glutathione peroxidases
5. Dual function of the selenoprotein PHGPx during sperm maturation
6. mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins
7. Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells
8. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line CaCo-2 in culture
9. Retinoic acid induces Gpx2 gene expression in MCF-7 human breast cancer cells
10. Structural organization of the human gastrointestinal glutathione peroxidase (GPX2) promoter and 3′-nontranscribed region: Transcriptional response to exogenous redox agents
11. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation
12. Polymorphism and chromosomal localization of the G1-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization
13. Genetic analysis of colon cancer susceptibility in mice
14. Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPx-G1
15. Inverse mRNA expression of the selenocysteine-containing proteins GI-GPx and SeP in colorectal adenomas compared with adjacent normal mucosa
16. Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue
17. Formation and transport of chylomicrons by enterocytes to the lymphatics
18. Functional redundancy of two glutathione peroxidase isozymes: GPx-1 and GPx-GI
19. Estimation of individual types of glutathione peroxidases
20. Synthesis of mono- and bifunctional peptide-dextran conjugates for the immobilization of peptide antigens on ELISA plates: Properties and application