Caffeoylserotonin protects human keratinocyte HaCaT cells against H 2O2-induced oxidative stress and apoptosis through upregulation of Ho-1 expression via activation of the Pi3k/Akt/Nrf2 pathway

Phytotherapy Research

Volumn 27, Issue 12, 2013, Pages 1810-1818

  Nguyen, Cam Ngoc ^a   Kim, Hye Eun ^a   Lee, Seong Gene ^a  

^a Chonnam National University   (South Korea)

Author keywords

antioxidant; caffeoylserotonin; heme oxygenase 1; hydrogen peroxide; keratinocyte; Nrf2

Indexed keywords

CAFFEOYLSEROTONIN; CASPASE 3; HEME OXYGENASE 1; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 3; PROTECTIVE AGENT; PROTEIN BAX; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN P21; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HUMAN CELL; KERATINOCYTE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANTIOXIDANT; CAFFEOYLSEROTONIN; HEME OXYGENASE-1; HYDROGEN PEROXIDE; KERATINOCYTE; NRF2;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CAFFEIC ACIDS; CELL LINE; ENZYME INHIBITORS; HEME OXYGENASE-1; HUMANS; HYDROGEN PEROXIDE; KERATINOCYTES; MAP KINASE SIGNALING SYSTEM; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SEROTONIN; UP-REGULATION;

EID: 84890553464     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4931     Document Type: Article

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