Triptolide inhibits IFN-γ signaling via the Jak/STAT pathway in HaCaT keratinocytes

Phytotherapy Research

Volumn 25, Issue 11, 2011, Pages 1678-1685

  Tu, Hongqin ^a,b   Li, Xinyu ^a   Gu, Heng ^a   Xu, Lanfang ^a   Wang, Yongfang ^a   Song, Shasha ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b YIXING PEOPLE S HOSPITAL   (China)

Author keywords

Interferon gamma; Janus kinase signal transducer and activator of transcription (Jak STAT); Keratinocyte; Tripterygium wilfordii Hook. F.; Triptolide

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; JANUS KINASE; JANUS KINASE 2; STAT PROTEIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRIPTOLIDE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IC 50; INTRACELLULAR SIGNALING; KERATINOCYTE; PROTEIN EXPRESSION; PSORIASIS; TRIPTERYGIUM; TRIPTERYGIUM WILFORDII; UPREGULATION; WESTERN BLOTTING;

CELL LINE; CELL SURVIVAL; DITERPENES; EPOXY COMPOUNDS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA; JANUS KINASE 2; KERATINOCYTES; PHENANTHRENES; PHOSPHORYLATION; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRIPTERYGIUM;

TRIPTERYGIUM WILFORDII;

EID: 80054955784     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3471     Document Type: Article

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