Antiinflammatory effects of traditional Korean medicine, JinPi-tang and its active ingredient, hesperidin in HaCaT cells

Phytotherapy Research

Volumn 26, Issue 5, 2012, Pages 657-662

  Moon, Phil Dong ^a   Kim, Hyung Mim ^a  

^a Kyung Hee University   (South Korea)

Author keywords

HaCaT cells; hesperidin; I B nuclear factor B; p38 mitogen activated protein kinase

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; HESPERIDIN; HYDROGEN PEROXIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; JINPI TANG; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CITRUS UNSHUI; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; KOREAN MEDICINE; NONHUMAN; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RUTACEAE; WESTERN BLOTTING; ZINGIBER OFFICALE; ZINGIBERACEAE;

ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; ENZYME-LINKED IMMUNOSORBENT ASSAY; HESPERIDIN; HUMANS; HYDROGEN PEROXIDE; I-KAPPA B PROTEINS; INTERLEUKIN-8; KERATINOCYTES; MEDICINE, KOREAN TRADITIONAL; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859926942     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3627     Document Type: Article

References (22)

1. Baumgartner RA, Yamada K, Deramo VA, Beaven MA,. 1994. Secretion of TNF-α from a rat mast cell line is a brefeldin A-sensitive and a calcium/protein kinase C-regulated process. J Immunol 153: 2609-2617. (Pubitemid 24278130)
2. Ben Trivedi A, Kitabatake N, Doi E,. 1990. Toxicity of dimethyl sulfoxide as a solvent in bioassay system with HeLa cells evaluated colorimetrically with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide. Agric Biol Chem 54: 2961-2966.
3. Bickers DR, Athar M,. 2006. Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol 126: 2565-2575. (Pubitemid 44764040)
4. Börsch-Haubold AG, Pasquet S, Watson SP,. 1998. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. SB 203580 also inhibits thromboxane synthase. J Biol Chem 273: 28766-28772. (Pubitemid 28507565)
5. Bouchama A, Knochel JP,. 2002. Heat stroke. N Engl J Med 346: 1978-1988.
6. Cao X, Liu M, Tuo J, Shen D, Chan CC,. 2010. The effects of quercetin in cultured human RPE cells under oxidative stress and in Ccl2/Cx3cr1 double deficient mice. Exp Eye Res 91: 15-25.
7. Dugasani S, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN,. 2010. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol 127: 515-520.
8. Guo X, Gerl RE, Schrader JW,. 2003. Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase. J Biol Chem 278: 22237-22242. (Pubitemid 36830270)
9. Hattori T, Obinata H, Ogawa A, et al,. 2008. G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid. J Invest Dermatol 128: 1123-1133. (Pubitemid 351543211)
10. Heck DE, Vetrano AM, Mariano TM, Laskin JD,. 2003. UVB light stimulates production of reactive oxygen species: unexpected role for catalase. J Biol Chem 278: 22432-22436. (Pubitemid 36830295)
11. Huh J,. 1999. DongUiBoGam. Bubin Publishers Co.: Seoul.
12. Ichihashi M, Ueda M, Budiyanto A, et al,. 2003. UV-induced skin damage. Toxicology 189: 21-39. (Pubitemid 36725021)
13. Karakurum M, Shreeniwas R, Chen J, et al,. 1994. Hypoxic induction of interleukin-8 gene expression in human endothelial cells. J Clin Invest 93: 1564-1570. (Pubitemid 24116393)
14. Katayama S, Ishikawa S, Fan MZ, Mine Y,. 2007. Oligophosphopeptides derived from egg yolk phosvitin up-regulate gamma-glutamylcysteine synthetase and antioxidant enzymes against oxidative stress in Caco-2 cells. J Agric Food Chem 55: 2829-2835. (Pubitemid 46668285)
15. Moon PD, Lee BH, Jeong HJ, et al,. 2007. Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IkappaB/NF-kappaB signal cascade in the human mast cell line HMC-1. Eur J Pharm 555: 218-225.
16. Petersen AB, Gniadecki R, Vicanova J, Thorn T, Wulf HC,. 2000. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytes. J Photochem Photobiol B 59: 123-131. (Pubitemid 32273347)
17. Schoonbroodt S, Legrand-Poels S, Best-Belpomme M, Piette J,. 1997. Activation of the NF-kappaB transcription factor in a T-lymphocytic cell line by hypochlorous acid. Biochem J 321: 777-785. (Pubitemid 27084888)
18. Suter MM, Schulze K, Bergman W, Welle M, Roosje P, Müller EJ,. 2009. The keratinocyte in epidermal renewal and defence. Vet Dermatol 20: 515-532.
19. Won HY, Sohn JH, Min HJ, et al,. 2010. Glutathione peroxidase 1 deficiency attenuates allergen-induced airway inflammation by suppressing Th2 and Th17 cell development. Antioxid Redox Signal 13: 575-587.
20. Woods GM, Malley RC, Muller HK,. 2005. The skin immune system and the challenge of tumour immunosurveillance. Eur J Dermatol 15: 63-69. (Pubitemid 40434626)
21. Yamamoto K, Kushima R, Kisaki O, Fujiyama Y, Okabe H,. 2003. Combined effect of hydrogen peroxide induced oxidative stress and IL-1 R on IL-8 production in CaCo-2 cells (a human colon carcinoma cell line) and normal intestinal epithelial cells. Inflammation 27: 123-128. (Pubitemid 36741333)
22. Yoo KM, Hwang IK, Park JH, Moon B,. 2009. Major phytochemical composition of 3 native Korean citrus varieties and bioactive activity on V79-4 cells induced by oxidative stress. J Food Sci 74: C462-C468.