-
1
-
-
0021934758
-
Chemoprevention of cancer.
-
Wattenberg, L. W., Chemoprevention of cancer. Cancer Res. 1985, 45, 1-8.
-
(1985)
Cancer Res.
, vol.45
, pp. 1-8
-
-
Wattenberg, L.W.1
-
2
-
-
0030242168
-
Chemoprevention of cancer.
-
Greenwald, P., Chemoprevention of cancer. Sci. Am. 1996, 275, 96-99.
-
(1996)
Sci. Am.
, vol.275
, pp. 96-99
-
-
Greenwald, P.1
-
3
-
-
33847284555
-
Apoptosis by dietary factors: The suicide solution for delaying cancer growth.
-
Khan, N., Afaq, F., Mukhtar, H., Apoptosis by dietary factors: The suicide solution for delaying cancer growth. Carcinogenesis 2007, 28, 233-239.
-
(2007)
Carcinogenesis
, vol.28
, pp. 233-239
-
-
Khan, N.1
Afaq, F.2
Mukhtar, H.3
-
4
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway.
-
Kensler, T. W., Wakabayashi, N., Biswal, S., Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007, 47, 89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
5
-
-
0031577292
-
An Nrf2 small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
-
Itoh, K., Chiba, T., Takahashi, S., Ishii, T. et al., An Nrf2 small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem.Biophys. Res. Commun. 1997, 236, 313-322.
-
(1997)
Biochem.Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
-
6
-
-
0035853101
-
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups.
-
Dinkova-Kostova, A. T., Massiah, M. A., Bozak, R. E., Hicks, R. J., Talalay, P., Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups. Proc. Natl. Acad. Sci. USA 2001, 98, 3404-3409.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3404-3409
-
-
Dinkova-Kostova, A.T.1
Massiah, M.A.2
Bozak, R.E.3
Hicks, R.J.4
Talalay, P.5
-
7
-
-
33644649421
-
Nrf2: A potential molecular target for cancer chemoprevention by natural compounds.
-
Jeong, W. S., Jun, M., Kong, A. N., Nrf2: A potential molecular target for cancer chemoprevention by natural compounds. Antioxid. Redox. Signal. 2006, 8, 99-106.
-
(2006)
Antioxid. Redox. Signal.
, vol.8
, pp. 99-106
-
-
Jeong, W.S.1
Jun, M.2
Kong, A.N.3
-
8
-
-
1242319541
-
Induction of quinone reductase as a primary screen for natural product anticarcinogens.
-
Kang, Y. H., Pezzuto, J. M., Induction of quinone reductase as a primary screen for natural product anticarcinogens. Methods Enzymol. 2004, 382, 380-414.
-
(2004)
Methods Enzymol.
, vol.382
, pp. 380-414
-
-
Kang, Y.H.1
Pezzuto, J.M.2
-
9
-
-
47849083585
-
Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults.
-
Osburn, W. O., Kensler, T. W., Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults. Mutat. Res. 2008, 659, 31-39.
-
(2008)
Mutat. Res.
, vol.659
, pp. 31-39
-
-
Osburn, W.O.1
Kensler, T.W.2
-
10
-
-
0033934953
-
Induction of the soybean phytoalexins coumestrol and glyceollin by Aspergillus.
-
Boue, S. M., Carter, C. H., Ehrlich, K. C., Cleveland, T. E., Induction of the soybean phytoalexins coumestrol and glyceollin by Aspergillus. J. Agric. Food Chem. 2000, 48, 2167-2172.
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 2167-2172
-
-
Boue, S.M.1
Carter, C.H.2
Ehrlich, K.C.3
Cleveland, T.E.4
-
11
-
-
70249086256
-
Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP.
-
Payton-Stewart, F., Schoene, N. W., Kim, Y. S., Burow, M. E. et al., Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP. Mol. Carcinog. 2009, 48, 862-871.
-
(2009)
Mol. Carcinog.
, vol.48
, pp. 862-871
-
-
Payton-Stewart, F.1
Schoene, N.W.2
Kim, Y.S.3
Burow, M.E.4
-
12
-
-
33845751547
-
Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis.
-
Salvo, V. A., Boue, S. M., Fonseca, J. P., Elliott, S. et al., Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis. Clin. Cancer Res. 2006, 12, 7159-7164.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 7159-7164
-
-
Salvo, V.A.1
Boue, S.M.2
Fonseca, J.P.3
Elliott, S.4
-
13
-
-
78649310318
-
Antioxidant activity of glyceollins derived from soybean elicited with Aspergillus sojae.
-
Kim, H. J., Suh, H. J., Kim, J. H., Park, S. et al., Antioxidant activity of glyceollins derived from soybean elicited with Aspergillus sojae. J. Agric. Food Chem. 2010, 58, 11633-11638.
-
(2010)
J. Agric. Food Chem.
, vol.58
, pp. 11633-11638
-
-
Kim, H.J.1
Suh, H.J.2
Kim, J.H.3
Park, S.4
-
14
-
-
77956242160
-
Antifungal activity of glyceollins isolated from soybean elicited with Aspergillus sojae.
-
Kim, H. J., Suh, H. J., Lee, C. H., Kim, J. H. et al., Antifungal activity of glyceollins isolated from soybean elicited with Aspergillus sojae. J. Agric. Food Chem. 2010, 58, 9483-9487.
-
(2010)
J. Agric. Food Chem.
, vol.58
, pp. 9483-9487
-
-
Kim, H.J.1
Suh, H.J.2
Lee, C.H.3
Kim, J.H.4
-
15
-
-
76449093122
-
Glyceollins, one of the phytoalexins derived from soybeans under fungal stress, enhance insulin sensitivity and exert insulinotropic actions.
-
Park, S., Ahn, I. S., Kim, J. H., Lee, M. R. et al., Glyceollins, one of the phytoalexins derived from soybeans under fungal stress, enhance insulin sensitivity and exert insulinotropic actions. J. Agric. Food Chem. 2010, 58, 1551-1557.
-
(2010)
J. Agric. Food Chem.
, vol.58
, pp. 1551-1557
-
-
Park, S.1
Ahn, I.S.2
Kim, J.H.3
Lee, M.R.4
-
16
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
-
Dinkova-Kostova, A. T., Holtzclaw, W. D., Cole, R. N., Itoh, K. et al., Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc. Natl. Acad. Sci. USA 2002, 99, 11908-11913.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
-
17
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.
-
Eggler, A. L., Liu, G., Pezzuto, J. M., van Breemen, R. B., Mesecar, A. D., Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc. Natl. Acad. Sci. USA 2005, 102, 10070-10075.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
van Breemen, R.B.4
Mesecar, A.D.5
-
18
-
-
78751703950
-
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
-
Taguchi, K., Motohashi, H., Yamamoto, M., Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 2011.
-
(2011)
Genes Cells
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
19
-
-
58149337235
-
Effects of light treatment on isoflavone content of germinated soybean seeds.
-
Phommalth, S., Jeong, Y. S., Kim, Y. H., Dhakal, K. H., Hwang, Y. H., Effects of light treatment on isoflavone content of germinated soybean seeds. J. Agric. Food Chem. 2008, 56, 10123-10128.
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 10123-10128
-
-
Phommalth, S.1
Jeong, Y.S.2
Kim, Y.H.3
Dhakal, K.H.4
Hwang, Y.H.5
-
20
-
-
0034723357
-
p38 nitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens.
-
Yu, R., Mandlekar, S., Lei, K., Fahl, W. E. et al., p38 nitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens. J. Biol. Chem. 2000, 275, 2322-2327.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2322-2327
-
-
Yu, R.1
Mandlekar, S.2
Lei, K.3
Fahl, W.E.4
-
21
-
-
0019142866
-
Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity.
-
Benson, A. M., Hunkeler, M. J., Talalay, P., Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity. Proc. Natl. Acad. Sci. USA 1980, 77, 5216-5220.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 5216-5220
-
-
Benson, A.M.1
Hunkeler, M.J.2
Talalay, P.3
-
22
-
-
76449115692
-
Dehydroglyasperin C isolated from licorice caused Nrf2-mediated induction of detoxifying enzymes.
-
Seo, J. Y., Lee, Y. S., Kim, H. J., Lim, S. S. et al., Dehydroglyasperin C isolated from licorice caused Nrf2-mediated induction of detoxifying enzymes. J. Agric. Food Chem. 2010, 58, 1603-1608.
-
(2010)
J. Agric. Food Chem.
, vol.58
, pp. 1603-1608
-
-
Seo, J.Y.1
Lee, Y.S.2
Kim, H.J.3
Lim, S.S.4
-
23
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs.
-
Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J. et al., Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 1997, 25, 3389-3402.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
-
24
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
-
Thompson, J. D., Higgins, D. G., Gibson, T. J., CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994, 22, 4673-4680.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
25
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints.
-
Sali, A., Blundell, T. L., Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 1993, 234, 779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
26
-
-
70450106216
-
Improved prediction of protein side-chain conformations with SCWRL4.
-
Krivov, G. G., Shapovalov, M. V., Dunbrack, R. L. Jr., Improved prediction of protein side-chain conformations with SCWRL4. Proteins 2009, 77, 778-795.
-
(2009)
Proteins
, vol.77
, pp. 778-795
-
-
Krivov, G.G.1
Shapovalov, M.V.2
Dunbrack, R.L.J.3
-
27
-
-
0000243829
-
PROCHECK: A program to check the stereochemical quality of protein structures.
-
Laskowski, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PROCHECK: A program to check the stereochemical quality of protein structures. J. Appl. Crystallogr. 1993, 26, 283-291.
-
(1993)
J. Appl. Crystallogr.
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
28
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination.
-
Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L. et al., Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 1998, 54, 905-921.
-
(1998)
Acta Crystallogr. D Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
-
29
-
-
13244281317
-
Coot: Model-building tools for molecular graphics.
-
Emsley, P., Cowtan, K., Coot: Model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 2004, 60, 2126-2132.
-
(2004)
Acta Crystallogr. D Biol. Crystallogr.
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
30
-
-
77956308900
-
Binding-site assessment by virtual fragment screening.
-
Huang, N., Jacobson, M. P., Binding-site assessment by virtual fragment screening. PLoS One 2010, 5, e10109.
-
(2010)
PLoS One
, vol.5
-
-
Huang, N.1
Jacobson, M.P.2
-
31
-
-
0023777834
-
Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver.
-
Prochaska, H. J., Talalay, P., Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res. 1988, 48, 4776-4782.
-
(1988)
Cancer Res.
, vol.48
, pp. 4776-4782
-
-
Prochaska, H.J.1
Talalay, P.2
-
32
-
-
0141560472
-
Modeling side-chain conformation.
-
Vasquez, M., Modeling side-chain conformation. Curr. Opin. Struct. Biol. 1996, 6, 217-221.
-
(1996)
Curr. Opin. Struct. Biol.
, vol.6
, pp. 217-221
-
-
Vasquez, M.1
-
33
-
-
59849113546
-
Molecular mechanisms of Nrf2-mediated antioxidant response.
-
Li, W., Kong, A. N., Molecular mechanisms of Nrf2-mediated antioxidant response. Mol. Carcinog. 2009, 48, 91-104.
-
(2009)
Mol. Carcinog.
, vol.48
, pp. 91-104
-
-
Li, W.1
Kong, A.N.2
-
34
-
-
77950352188
-
An internal ribosomal entry site mediates redox-sensitive translation of Nrf2.
-
Li, W. G., Thakor, N., Xu, E. Y., Huang, Y. et al., An internal ribosomal entry site mediates redox-sensitive translation of Nrf2. Nucleic Acids Res. 2010, 38, 778-788.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 778-788
-
-
Li, W.G.1
Thakor, N.2
Xu, E.Y.3
Huang, Y.4
-
35
-
-
58249117780
-
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds.
-
Kobayashi, M., Li, L., Iwamoto, N., Nakajima-Takagi, Y. et al., The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol. Cell. Biol. 2009, 29, 493-502.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 493-502
-
-
Kobayashi, M.1
Li, L.2
Iwamoto, N.3
Nakajima-Takagi, Y.4
-
36
-
-
25444449520
-
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.
-
Nguyen, T., Sherratt, P. J., Nioi, P., Yang, C. S., Pickett, C. B., Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1. J. Biol. Chem. 2005, 280, 32485-32492.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32485-32492
-
-
Nguyen, T.1
Sherratt, P.J.2
Nioi, P.3
Yang, C.S.4
Pickett, C.B.5
-
37
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
-
Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H. et al., Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat. Genet. 2003, 35, 238-245.
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
-
38
-
-
0242610791
-
Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane.
-
Kim, B. R., Hu, R., Keum, Y. S., Hebbar, V. et al., Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane. Cancer Res. 2003, 63, 7520-7525.
-
(2003)
Cancer Res.
, vol.63
, pp. 7520-7525
-
-
Kim, B.R.1
Hu, R.2
Keum, Y.S.3
Hebbar, V.4
-
39
-
-
0038537298
-
PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells.
-
Nakaso, K., Yano, H., Fukuhara, Y., Takeshima, T. et al., PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells. FEBS Lett. 2003, 546, 181-184.
-
(2003)
FEBS Lett.
, vol.546
, pp. 181-184
-
-
Nakaso, K.1
Yano, H.2
Fukuhara, Y.3
Takeshima, T.4
|