메뉴 건너뛰기




Volumn 23, Issue 1, 2014, Pages 80-86

Where are we in diabetic nephropathy: MicroRNAs and biomarkers

Author keywords

biomarkers, fibrosis, microRNA, TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BIOLOGICAL MARKER; COLLAGEN TYPE 2; FIBRONECTIN; GELATINASE B; MICRORNA; MICRORNA 192; MICRORNA 200; MICRORNA 200A; MICRORNA 200B; MICRORNA 29; MICRORNA 29A; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD PROTEIN; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 2; UVOMORULIN; VIMENTIN;

EID: 84890547522     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/01.mnh.0000437612.50040.ae     Document Type: Review
Times cited : (29)

References (44)
  • 1
    • 1342268353 scopus 로고    scopus 로고
    • Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
    • Li JH, Huang XR, Zhu HJ, et al. Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease. FASEB J 2004; 18:176-178.
    • (2004) FASEB J , vol.18 , pp. 176-178
    • Li, J.H.1    Huang, X.R.2    Zhu, H.J.3
  • 2
    • 1642336325 scopus 로고    scopus 로고
    • Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGEERK1/2 MAP kinase signaling pathway
    • Li JH, Wang W, Huang XR, et al. Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGEERK1/2 MAP kinase signaling pathway. Am J Pathol 2004; 164:1389-1397.
    • (2004) Am J Pathol , vol.164 , pp. 1389-1397
    • Li, J.H.1    Wang, W.2    Huang, X.R.3
  • 3
    • 77956548300 scopus 로고    scopus 로고
    • Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis
    • Meng XM, Huang XR, Chung AC, et al. Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. J Am Soc Nephrol 2010; 21:1477-1487.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1477-1487
    • Meng, X.M.1    Huang, X.R.2    Chung, A.C.3
  • 4
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: New insights in signaling, development, and disease. J Cell Biol 2006; 172:973-981.
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 5
    • 33748756028 scopus 로고    scopus 로고
    • TGF-beta: A mobile purveyor of immune privilege
    • Wahl SM, Wen J, Moutsopoulos N. TGF-beta: A mobile purveyor of immune privilege. Immunol Rev 2006; 213:213-227.
    • (2006) Immunol Rev , vol.213 , pp. 213-227
    • Wahl, S.M.1    Wen, J.2    Moutsopoulos, N.3
  • 6
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 7
    • 79954623314 scopus 로고    scopus 로고
    • TGF-beta regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4
    • Winbanks CE, Wang B, Beyer C, et al. TGF-beta regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4. J Biol Chem 2011; 286:13805-13814.
    • (2011) J Biol Chem , vol.286 , pp. 13805-13814
    • Winbanks, C.E.1    Wang, B.2    Beyer, C.3
  • 8
    • 42449086421 scopus 로고    scopus 로고
    • MiR-148 targets human DNMT3b protein coding region
    • Duursma AM, Kedde M, Schrier M, et al. miR-148 targets human DNMT3b protein coding region. RNA 2008; 14:872-877.
    • (2008) RNA , vol.14 , pp. 872-877
    • Duursma, A.M.1    Kedde, M.2    Schrier, M.3
  • 9
    • 55849135596 scopus 로고    scopus 로고
    • MicroRNA-directed transcriptional gene silencing in mammalian cells
    • Kim DH, Saetrom P, Snove O Jr, Rossi JJ. MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc Natl Acad Sci U S A 2008; 105:16230-16235.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 16230-16235
    • Kim, D.H.1    Saetrom, P.2    Snove Jr., O.3    Rossi, J.J.4
  • 10
    • 79959347056 scopus 로고    scopus 로고
    • Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters
    • Younger ST, Corey DR. Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters. Nucleic Acids Res 2011; 39:5682-5691.
    • (2011) Nucleic Acids Res , vol.39 , pp. 5682-5691
    • Younger, S.T.1    Corey, D.R.2
  • 11
    • 77955602944 scopus 로고    scopus 로고
    • Resolved: EMT produces fibroblasts in the kidney
    • Zeisberg M, Duffield JS. Resolved: EMT produces fibroblasts in the kidney. J Am Soc Nephrol 2010; 21:1247-1253.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1247-1253
    • Zeisberg, M.1    Duffield, J.S.2
  • 13
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119:1420-1428.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 14
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22:894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 15
    • 15444344415 scopus 로고    scopus 로고
    • 14-3-3 Protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain
    • Ogihara T. 14-3-3 Protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. J Biol Chem 1997; 272:25267-25274.
    • (1997) J Biol Chem , vol.272 , pp. 25267-25274
    • Ogihara, T.1
  • 16
    • 84881161493 scopus 로고    scopus 로고
    • A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-beta1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis
    • This study demostrated the induction of UCP2 after TGF-b-mediated downregulation of miR-30e
    • Jiang L, Qiu W, Zhou Y, et al. A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-beta1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis. Kidney Int 2013; 84:285-296. This study demostrated the induction of UCP2 after TGF-b-mediated downregulation of miR-30e.
    • (2013) Kidney Int , vol.84 , pp. 285-296
    • Jiang, L.1    Qiu, W.2    Zhou, Y.3
  • 17
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351:1296-1305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3
  • 18
    • 84890548998 scopus 로고    scopus 로고
    • Microrna as biomarkers and regulator of cardiovascular development and disease
    • [Epub ahead of print]
    • Hagiwara S, Kantharidis P, Cooper ME. microRNA as biomarkers and regulator of cardiovascular development and disease. Curr Pharm Des 2013. [Epub ahead of print]
    • (2013) Curr Pharm des
    • Hagiwara, S.1    Kantharidis Cooper, P.M.E.2
  • 19
    • 84878094151 scopus 로고    scopus 로고
    • Decreased microRNA is involved in the vascular remodeling abnormalities in chronic kidney disease (CKD)
    • This study identified elevated mir-145 and miR-155 levels in blood in patients with CKD
    • Chen NX, Kiattisunthorn K, O'Neill KD, et al. Decreased microRNA is involved in the vascular remodeling abnormalities in chronic kidney disease (CKD). PloS One 2013; 8:e64558. This study identified elevated mir-145 and miR-155 levels in blood in patients with CKD.
    • (2013) PloS One , vol.8
    • Chen, N.X.1    Kiattisunthorn, K.2    O'Neill, K.D.3
  • 20
    • 80051981239 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes
    • Jeppesen PL, Christensen GL, Schneider M, et al. Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes. Br J Pharmacol 2011; 164:394-404.
    • (2011) Br J Pharmacol , vol.164 , pp. 394-404
    • Jeppesen, P.L.1    Christensen, G.L.2    Schneider, M.3
  • 21
    • 84860849258 scopus 로고    scopus 로고
    • Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells
    • This is the study showing that miR-132 and miR-212 are induced by AngII in VSMCs
    • Jin W, Reddy MA, Chen Z, et al. Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells. J Biol Chem 2012; 287:15672-15683. This is the study showing that miR-132 and miR-212 are induced by AngII in VSMCs
    • (2012) J Biol Chem , vol.287 , pp. 15672-15683
    • Jin, W.1    Reddy, M.A.2    Chen, Z.3
  • 22
    • 84878448365 scopus 로고    scopus 로고
    • Angiotensin II regulates microRNA-132/-212 in hypertensive rats and humans
    • This study shows that miR-132 and miR-212 are significantly increased in tissues associated with blood pressure control such as kidney and heart by AngII, and reduced in ARB-treated patients
    • Eskildsen TV, Jeppesen PL, Schneider M, et al. Angiotensin II regulates microRNA-132/-212 in hypertensive rats and humans. Int J Mol Sci 2013; 14:11190-11207. This study shows that miR-132 and miR-212 are significantly increased in tissues associated with blood pressure control such as kidney and heart by AngII, and reduced in ARB-treated patients.
    • (2013) Int J Mol Sci , vol.14 , pp. 11190-11207
    • Eskildsen, T.V.1    Jeppesen, P.L.2    Schneider, M.3
  • 23
    • 77958060961 scopus 로고    scopus 로고
    • Identification of novel genetic markers and improved treatment options for diabetic kidney disease
    • DiStefano JK. Identification of novel genetic markers and improved treatment options for diabetic kidney disease. Biomarkers Med 2010; 4:739-741.
    • (2010) Biomarkers Med , vol.4 , pp. 739-741
    • Distefano, J.K.1
  • 24
    • 84863402040 scopus 로고    scopus 로고
    • Towards understanding the inherited susceptibility for nephropathy in diabetes
    • Thomas MC, Groop PH, Tryggvason K. Towards understanding the inherited susceptibility for nephropathy in diabetes. Curr Opin Nephrol Hypertens 2012; 21:195-202.
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , pp. 195-202
    • Thomas, M.C.1    Groop, P.H.2    Tryggvason, K.3
  • 25
    • 77957259803 scopus 로고    scopus 로고
    • Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
    • Zampetaki A, Kiechl S, Drozdov I, et al. Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res 2010; 107:810-817.
    • (2010) Circ Res , vol.107 , pp. 810-817
    • Zampetaki, A.1    Kiechl, S.2    Drozdov, I.3
  • 26
    • 84857932052 scopus 로고    scopus 로고
    • Role of microRNAs in diabetes and its cardiovascular complications
    • Shantikumar S, Caporali A, Emanueli C. Role of microRNAs in diabetes and its cardiovascular complications. Cardiovas Res 2012; 93:583-593.
    • (2012) Cardiovas Res , vol.93 , pp. 583-593
    • Shantikumar, S.1    Caporali, A.2    Emanueli, C.3
  • 27
    • 78449295450 scopus 로고    scopus 로고
    • Pathway activity profiling (PAPi): From the metabolite profile to the metabolic pathway activity
    • Aggio RB, Ruggiero K, Villas-Boas SG. Pathway activity profiling (PAPi): From the metabolite profile to the metabolic pathway activity. Bioinformatics 2010; 26:2969-2976.
    • (2010) Bioinformatics , vol.26 , pp. 2969-2976
    • Aggio, R.B.1    Ruggiero, K.2    Villas-Boas, S.G.3
  • 28
    • 84872860732 scopus 로고    scopus 로고
    • Urinary microRNA profiling in the nephropathy of type 1 diabetes
    • Argyropoulos C, Wang K, McClarty S, et al. Urinary microRNA profiling in the nephropathy of type 1 diabetes. PloS One 2013; 8:e54662.
    • (2013) PloS One , vol.8
    • Argyropoulos, C.1    Wang, K.2    McClarty, S.3
  • 29
    • 84871347378 scopus 로고    scopus 로고
    • Urinary microRNA-10a and microRNA-30d serve as novel, sensitive and specific biomarkers for kidney injury
    • Wang N, Zhou Y, Jiang L, et al. Urinary microRNA-10a and microRNA-30d serve as novel, sensitive and specific biomarkers for kidney injury. PloS One 2012; 7:e51140.
    • (2012) PloS One , vol.7
    • Wang, N.1    Zhou, Y.2    Jiang, L.3
  • 30
    • 84867529562 scopus 로고    scopus 로고
    • Micro-RNA expression in the urinary sediment of patients with chronic kidney diseases
    • Szeto CC, Ching-Ha KB, Ka-Bik L, et al. Micro-RNA expression in the urinary sediment of patients with chronic kidney diseases. Dis Markers 2012; 33:137-144.
    • (2012) Dis Markers , vol.33 , pp. 137-144
    • Szeto, C.C.1    Ching-Ha, K.B.2    Ka-Bik, L.3
  • 31
    • 84867897248 scopus 로고    scopus 로고
    • Urinary miR-21, miR-29, and miR-93: Novel biomarkers of fibrosis
    • Wang G, Kwan BC, Lai FM, et al. Urinary miR-21, miR-29, and miR-93: Novel biomarkers of fibrosis. Am J Nephrol 2012; 36:412-428.
    • (2012) Am J Nephrol , vol.36 , pp. 412-428
    • Wang, G.1    Kwan, B.C.2    Lai, F.M.3
  • 32
    • 84874558141 scopus 로고    scopus 로고
    • Increased circulating miR-21 levels are associated with kidney fibrosis
    • Glowacki F, Savary G, Gnemmi V, et al. Increased circulating miR-21 levels are associated with kidney fibrosis. PloS One 2013; 8:e58014.
    • (2013) PloS One , vol.8
    • Glowacki, F.1    Savary, G.2    Gnemmi, V.3
  • 34
    • 80052342295 scopus 로고    scopus 로고
    • MiR-21 and miR-214 are consistently modulated during renal injury in rodent models
    • Denby L, Ramdas V, McBride MW, et al. miR-21 and miR-214 are consistently modulated during renal injury in rodent models. Am J Pathol 2011; 179:661-672.
    • (2011) Am J Pathol , vol.179 , pp. 661-672
    • Denby, L.1    Ramdas, V.2    McBride, M.W.3
  • 35
    • 80052316668 scopus 로고    scopus 로고
    • Smad3-mediated upregulation of miR-21 promotes renal fibrosis
    • Zhong X, Chung AC, Chen HY, et al. Smad3-mediated upregulation of miR-21 promotes renal fibrosis. J Am Soc Nephrol 2011; 22:1668-1681.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1668-1681
    • Zhong, X.1    Chung, A.C.2    Chen, H.Y.3
  • 36
    • 79951820519 scopus 로고    scopus 로고
    • MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells
    • Sabatel C, Malvaux L, Bovy N, et al. MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells. PloS One 2011; 6:e16979.
    • (2011) PloS One , vol.6
    • Sabatel, C.1    Malvaux, L.2    Bovy, N.3
  • 37
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008; 456:980-984.
    • (2008) Nature , vol.456 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 38
    • 80054973471 scopus 로고    scopus 로고
    • MiR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study
    • Raitoharju E, Lyytikainen LP, Levula M, et al. miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study. Atherosclerosis 2011; 219:211-217.
    • (2011) Atherosclerosis , vol.219 , pp. 211-217
    • Raitoharju, E.1    Lyytikainen, L.P.2    Levula, M.3
  • 39
    • 80052102044 scopus 로고    scopus 로고
    • Diabetes complications: The microRNA perspective
    • Kantharidis P, Wang B, Carew RM, Lan HY. Diabetes complications: The microRNA perspective. Diabetes 2011; 60:1832-1837.
    • (2011) Diabetes , vol.60 , pp. 1832-1837
    • Kantharidis, P.1    Wang, B.2    Carew, R.M.3    Lan, H.Y.4
  • 40
    • 80052333875 scopus 로고    scopus 로고
    • MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats
    • Kovacs B, Lumayag S, Cowan C, Xu S. MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats. Invest Ophthalmol Visual Sci 2011; 52:4402-4409.
    • (2011) Invest Ophthalmol Visual Sci , vol.52 , pp. 4402-4409
    • Kovacs, B.1    Lumayag, S.2    Cowan, C.3    Xu, S.4
  • 41
    • 51349141401 scopus 로고    scopus 로고
    • Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
    • van Rooij E, Sutherland LB, Thatcher JE, et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A 2008; 105:13027-13032.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13027-13032
    • Van Rooij, E.1    Sutherland, L.B.2    Thatcher, J.E.3
  • 42
    • 79960322580 scopus 로고    scopus 로고
    • MiR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)
    • Pullen TJ, da Silva Xavier G, Kelsey G, Rutter GA. miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1). Mol Cell Biol 2011; 31:3182-3194.
    • (2011) Mol Cell Biol , vol.31 , pp. 3182-3194
    • Pullen, T.J.1    Da Silva Xavier, G.2    Kelsey, G.3    Rutter, G.A.4
  • 43
    • 84858776574 scopus 로고    scopus 로고
    • MicroRNAs in metabolism and metabolic disorders
    • Rottiers V, Naar AM. MicroRNAs in metabolism and metabolic disorders. Nat Rev Mol Cell Biol 2012; 13:239-250.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 239-250
    • Rottiers, V.1    Naar, A.M.2
  • 44
    • 84880044154 scopus 로고    scopus 로고
    • Urine miRNAs: Potential biomarkers for monitoring progression of early stages of diabetic nephropathy
    • Yang Y, Xiao L, Li J, et al. Urine miRNAs: Potential biomarkers for monitoring progression of early stages of diabetic nephropathy. Med Hypotheses 2013; 81:274-278.
    • (2013) Med Hypotheses , vol.81 , pp. 274-278
    • Yang, Y.1    Xiao, L.2    Li, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.