A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis

Kidney International

Volumn 84, Issue 2, 2013, Pages 285-296

  Jiang, Lei ^a   Qiu, Wenjing ^a   Zhou, Yang ^a   Wen, Ping ^a   Fang, Li ^a   Cao, Hongdi ^a   Zen, Ke ^b   He, Weichun ^a   Zhang, Chenyu ^b   Dai, Chunsun ^a   Yang, Junwei ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

MicroRNA; Mitochondria; Renal fibrosis; Tubular epithelial cell; UCP2

Indexed keywords

GENIPIN; MESSENGER RNA; MICRORNA; MICRORNA 30E; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINE; CELL STRAIN NRK 52E; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; EXTRACELLULAR MATRIX; IN SITU HYBRIDIZATION; KIDNEY FIBROSIS; KIDNEY TUBULAR EPITHELIAL CELL; KIDNEY TUBULE CELL; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; URETER OBSTRUCTION; WESTERN BLOTTING;

ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROSIS; HUMANS; ION CHANNELS; IRIDOIDS; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; MITOCHONDRIAL PROTEINS; RATS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84881161493     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.80     Document Type: Article

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