메뉴 건너뛰기




Volumn 9780199532872, Issue , 2009, Pages

Association studies

(2)  Webb, Emily a   Houlston, Richard a  

a NONE

Author keywords

Association; Complex disease; Genetic susceptibility; Multipoint test; Power; Single locus test; Study design

Indexed keywords

COMPLEX DISEASE; GENETIC SUSCEPTIBILITY; POWER; PRELIMINARY ANALYSIS; STATISTICAL APPROACH; STATISTICAL POWER; STUDY DESIGN; TECHNOLOGICAL ADVANCES;

EID: 84890501880     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1093/acprof:oso/9780199532872.003.0001     Document Type: Chapter
Times cited : (2)

References (52)
  • 2
    • 0016286319 scopus 로고
    • Genetic study of breast cancer: identification of a high risk group
    • Anderson, D. E. (1974). Genetic study of breast cancer: identification of a high risk group. Cancer, 34, 1090-7.
    • (1974) Cancer , vol.34 , pp. 1090-1097
    • Anderson, D.E.1
  • 3
    • 0033740880 scopus 로고    scopus 로고
    • Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases
    • Anglian Breast Cancer Study Group (2000). Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. British Journal of Cancer, 83, 1301-8.
    • (2000) British Journal of Cancer , vol.83 , pp. 1301-1308
  • 4
    • 0142063079 scopus 로고    scopus 로고
    • Polygenic inheritance of breast cancer:Implications for design of association studies
    • Antoniou, A. C. and Easton, D. F. (2003). Polygenic inheritance of breast cancer:Implications for design of association studies. Genetic Epidemiology, 25, 190-202.
    • (2003) Genetic Epidemiology , vol.25 , pp. 190-202
    • Antoniou, A.C.1    Easton, D.F.2
  • 5
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett, J. C., Fry, B., Maller, J., and Daly, M. J. (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics, 21, 263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 6
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society B, 57, 289-300.
    • (1995) Journal of the Royal Statistical Society B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 9
    • 0037373275 scopus 로고    scopus 로고
    • Discovering genotypes underlying human phenotypes:past successes for mendelian disease, future approaches for complex disease
    • Botstein, D. and Risch, N. (2003). Discovering genotypes underlying human phenotypes:past successes for mendelian disease, future approaches for complex disease. Nature Genetics, 33 Suppl, 228-37.
    • (2003) Nature Genetics , vol.33 , Issue.SUPPL , pp. 228-237
    • Botstein, D.1    Risch, N.2
  • 12
    • 3042582651 scopus 로고    scopus 로고
    • Chek2*1100delc and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies
    • CHEK2 Breast Cancer Case-Control Consortium (2004). Chek2*1100delc and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. American Journal of Human Genetics, 74, 1175-82.
    • (2004) American Journal of Human Genetics , vol.74 , pp. 1175-1182
  • 14
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin, B. and Roeder, K. (1999). Genomic control for association studies. Biometrics, 55, 997-1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 15
    • 4143076901 scopus 로고    scopus 로고
    • Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies
    • Dudbridge, F. and Koeleman, B. P. (2004). Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. American Journal of Human Genetics, 75, 424-35.
    • (2004) American Journal of Human Genetics , vol.75 , pp. 424-435
    • Dudbridge, F.1    Koeleman, B.P.2
  • 18
    • 0016197604 scopus 로고
    • Amino acid difference formula to help explain protein evolution
    • Grantham, R. (1974). Amino acid difference formula to help explain protein evolution. Science, 185, 862-4.
    • (1974) Science , vol.185 , pp. 862-864
    • Grantham, R.1
  • 20
    • 0038823932 scopus 로고    scopus 로고
    • The future of association studies of common cancers
    • Houlston, R. S. and Peto, J. (2003). The future of association studies of common cancers. Human Genetics, 112, 434-5.
    • (2003) Human Genetics , vol.112 , pp. 434-435
    • Houlston, R.S.1    Peto, J.2
  • 21
    • 0034909923 scopus 로고    scopus 로고
    • Polymorphisms and colorectal tumor risk
    • Houlston, R. S. and Tomlinson, I. P. (2001). Polymorphisms and colorectal tumor risk. Gastroenterology, 121, 282-301.
    • (2001) Gastroenterology , vol.121 , pp. 282-301
    • Houlston, R.S.1    Tomlinson, I.P.2
  • 22
    • 34447527602 scopus 로고    scopus 로고
    • MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer
    • Hubner, R. A., Lubbe, S., Chandler, I., and Houlston, R. (2007). MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer. Human Molecular Genetics, 16, 1072-7.
    • (2007) Human Molecular Genetics , vol.16 , pp. 1072-1077
    • Hubner, R.A.1    Lubbe, S.2    Chandler, I.3    Houlston, R.4
  • 24
    • 0027485551 scopus 로고
    • Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
    • Lindblom, A., Tannergrd, P., Werelius, B., and Nordenskjöld, M. (1993). Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nature Genetics, 5, 279-82.
    • (1993) Nature Genetics , vol.5 , pp. 279-282
    • Lindblom, A.1    Tannergrd, P.2    Werelius, B.3    Nordenskjöld, M.4
  • 25
    • 16844366786 scopus 로고    scopus 로고
    • Genome-wide strategies for detecting multiple loci that influence complex diseases
    • Marchini, J., Donnelly, P., and Cardon, L. R. (2005). Genome-wide strategies for detecting multiple loci that influence complex diseases. Nature Genetics, 37, 413-7.
    • (2005) Nature Genetics , vol.37 , pp. 413-417
    • Marchini, J.1    Donnelly, P.2    Cardon, L.R.3
  • 26
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini, J., Howie, B., Myers, S., McVean, G., and Donnelly, P. (2007). A new multipoint method for genome-wide association studies by imputation of genotypes. Nature Genetics, 39, 906-13.
    • (2007) Nature Genetics , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 28
    • 18544389716 scopus 로고    scopus 로고
    • Lowpenetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
    • Meijers-Heijboer, H., van den Ouweland, A., Klijn, J., and Wasielewski, M. (2002). Lowpenetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nature Genetics, 31, 55-9.
    • (2002) Nature Genetics , vol.31 , pp. 55-59
    • Meijers-Heijboer, H.1    van den Ouweland, A.2    Klijn, J.3    Wasielewski, M.4
  • 29
    • 33751112507 scopus 로고    scopus 로고
    • Mapping trait loci by use of inferred ancestral recombination graphs
    • Minichiello, M. J. and Durbin, R. (2006). Mapping trait loci by use of inferred ancestral recombination graphs. American Journal of Human Genetics, 79, 910-22.
    • (2006) American Journal of Human Genetics , vol.79 , pp. 910-922
    • Minichiello, M.J.1    Durbin, R.2
  • 30
    • 0035026704 scopus 로고    scopus 로고
    • Predicting deleterious amino acid substitutions
    • Ng, P. C. and Henikoff, S. (2001). Predicting deleterious amino acid substitutions. Genome Research, 11, 863-74.
    • (2001) Genome Research , vol.11 , pp. 863-874
    • Ng, P.C.1    Henikoff, S.2
  • 31
    • 0027263363 scopus 로고
    • Genetic mapping of a locus predisposing to human colorectal cancer
    • Peltomaki, P., Aaltonen, L. A., Sistonen, P., and L, L. Pylkkänen (1993). Genetic mapping of a locus predisposing to human colorectal cancer. Science, 260, 810-2.
    • (1993) Science , vol.260 , pp. 810-812
    • Peltomaki, P.1    Aaltonen, L.A.2    Sistonen, P.3    Pylkkänen, L.L.4
  • 32
    • 0004280656 scopus 로고
    • Genetic predisposition to cancer
    • ed. G. J, L. JL, and S. M, Cold Spring Harbor, N.Y.:Cold Spring Harbor Laboratory
    • Peto, J. (1980). Genetic predisposition to cancer. In Banbury Report 4: Cancer Incidence in Defined Populations (ed. G. J, L. JL, and S. M), pp. 203-213. Cold Spring Harbor, N.Y.:Cold Spring Harbor Laboratory.
    • (1980) Banbury Report 4: Cancer Incidence in Defined Populations , pp. 203-213
    • Peto, J.1
  • 33
    • 0036595321 scopus 로고    scopus 로고
    • Breast cancer susceptibility-a new look at an old model
    • Peto, J. (2002). Breast cancer susceptibility-a new look at an old model. Cancer Cell, 1, 411-2.
    • (2002) Cancer Cell , vol.1 , pp. 411-412
    • Peto, J.1
  • 35
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., and Reich, D. (2006). Principal components analysis corrects for stratification in genome-wide association studies. Nature Genetics, 38, 904-9.
    • (2006) Nature Genetics , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 36
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard, J. K., Stephens, M., and Donnelly, P. (2000). Inference of population structure using multilocus genotype data. Genetics, 155, 945-59.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 37
    • 0036713510 scopus 로고    scopus 로고
    • Human non-synonymous SNPs: server and survey
    • Ramensky, V., Bork, P., and Sunyaev, S. (2002). Human non-synonymous SNPs: server and survey. Nucleic Acids Research, 30, 3894-900.
    • (2002) Nucleic Acids Research , vol.30 , pp. 3894-3900
    • Ramensky, V.1    Bork, P.2    Sunyaev, S.3
  • 38
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch, N. and Merikangas, K. (1996). The future of genetic studies of complex human diseases. Science, 273, 1516-7.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 39
    • 0032427048 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling
    • Risch, N. and Teng, J. (1998). The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Research, 8, 1273-88.
    • (1998) Genome Research , vol.8 , pp. 1273-1288
    • Risch, N.1    Teng, J.2
  • 40
    • 33745952966 scopus 로고    scopus 로고
    • Variants in the atm-brca2-chek2 axis predispose to chronic lymphocytic leukemia
    • Rudd, M. F., Sellick, G. S., Webb, E. L., Catovsky, D., and Houlston, R. S. (2006a). Variants in the atm-brca2-chek2 axis predispose to chronic lymphocytic leukemia. Blood, 108, 638-44.
    • (2006) Blood , vol.108 , pp. 638-644
    • Rudd, M.F.1    Sellick, G.S.2    Webb, E.L.3    Catovsky, D.4    Houlston, R.S.5
  • 42
    • 0031466983 scopus 로고    scopus 로고
    • From genotypes to genes: doubling the sample size
    • Sasieni, P. D. (1997). From genotypes to genes: doubling the sample size. Biometrics, 53, 1253-61.
    • (1997) Biometrics , vol.53 , pp. 1253-1261
    • Sasieni, P.D.1
  • 43
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
    • Smyth, D. J., Cooper, J. D., Bailey, R., Field, S., and Burren, C. (2006). A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nature Genetics, 38, 617-9.
    • (2006) Nature Genetics , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3    Field, S.4    Burren, C.5
  • 44
  • 45
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens, M., Smith, N., and Donnelly, P. (2001). A new statistical method for haplotype reconstruction from population data. American Journal of Human Genetics, 68, 978-989.
    • (2001) American Journal of Human Genetics , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.2    Donnelly, P.3
  • 46
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Consortium (2003). The International HapMap Project. Nature, 426, 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 52
    • 0030812695 scopus 로고    scopus 로고
    • Sample size requirements in caseonly designs to detect gene-environment interaction
    • Yang, Q., Khoury, M. J., and Flanders, W. D. (1997). Sample size requirements in caseonly designs to detect gene-environment interaction. American Journal of Epidemiology, 146, 713-720.
    • (1997) American Journal of Epidemiology , vol.146 , pp. 713-720
    • Yang, Q.1    Khoury, M.J.2    Flanders, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.