Sample size requirements in case-only designs to detect gene-environment interaction

American Journal of Epidemiology

Volumn 146, Issue 9, 1997, Pages 713-720

  Yang, Quanhe ^a   Khoury, Muin J ^b   Flanders, W Dana ^c  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Case control studies; Epidemiologic methods; Gene environment interaction; Genes; Sample size

Indexed keywords

ARTICLE; ENVIRONMENTAL FACTOR; GENE LINKAGE GROUP; GENE TECHNOLOGY; GENETIC SUSCEPTIBILITY; GENOTYPE; MARKER GENE; RESEARCH;

EID: 0030812695     PISSN: 00029262     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.aje.a009346     Document Type: Article

References (23)

1. Cartwright RA, Glashan RW, Rogers HJ, et al. Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic-epidemiological approach to bladder cancer. Lancet 1982;2:842-6.
2. Caporaso N, Hayes RB, Dosemeci M, et al. Lung cancer risk, occupational exposure and the debrisoquine metabolic phenotype. Cancer Res 1989;49:3675-9.
3. Caporaso N, Landi MT, Vineis P. Relevance of metabolic polymorphism to human carcinogenesis: evaluation of epidemiologic evidence. Pharmacogenetics 1991;1:4-19.
4. Shields PG. Inherited factors and environmental exposure in cancer risk. J Occup Med 1993;35:34-41.
5. Hayes RB, Bi W, Rothman N, et al. N-acetylation phenotype and genotype and risk of bladder cancer in benzidine-exposed workers. Carcinogenesis 1993;14:675-8.
6. Hwang SJ, Beaty TH, Panny SR, et al. Association study of transforming growth factor alpha (TGFα) TaqI polymorphism and oral clefts: indication of gene-environment interaction in a population-based sample of infants with birth defects. Am J Epidemiol 1995;141:629-36.
7. Shaw GM, Wasserman CR, Lammer EJ, et al. Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants. Am J Human Genet 1996;58:551-61.
8. Ambrosone CB, Freudenheim JL, Graham S, et al. Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms, and breast cancer risk. JAMA 1996;276:1419-1521.
9. Khoury MJ, Flanders WD. Non-traditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls! Am J Epidemiol 1996;144:207-13.
10. Piegorsch WW, Weinberg CR, Taylor JA. Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies. Stat Med 1994;13:153-62.
11. Begg CB, Zhang ZF. Statistical analysis of molecular epidemiology studies employing case-series. Cancer Epidemiol Biomarkers Prev 1994;3:173-5.
12. Hwang SJ, Beaty TH, Liang KY, et al. Minimum sample size estimation to detect gene-environment interaction in case-control designs. Am J Epidemiol 1994;140:1029-37.
13. Khoury MJ, Beaty TH, Hwang SJ. Detection of genotype-environment interaction in case-control studies of birth defects: how big a sample size? Teratology 1995;51:336-43.
14. Smith PG, Day NE. The design of case-control studies: the influence of confounding and interaction effects. Int J Epidemiol 1984;13:356-65.
15. Windham GC, Swan SH, Fenster L. Parental cigarette smoking and the risk of spontaneous abortion. Am J Epidemiol 1992;135:1394-1403.
16. Fox SH, Koepsell TD, Daling JR. Birth weight and smoking during pregnancy-effect modification by maternal age. Am J Epidemiol 1994;139:1008-15.
17. Zhang J, Savitz DA, Schwingl PJ, et al. A case-control study of paternal smoking and birth defects. Int J Epidemiol 1992;21:273-78.
18. Sherman DI, Ward RJ, Yoshida A, et al. Alcohol and aldehyde dehydrogenase gene polymorphism and alcoholism. EXS 1994;71:291-300.
19. Chen CC, Hwu HG, Yeh EK, et al. Aldehyde dehydrogenase deficiency, flush patterns and prevalence of alcoholism: an interethnic comparison. Acta Med Okayama 1991;45:409-16.
20. Greenland S. Basic problems in interaction assessment. Environ Health Perspect 1993;101(suppl 4):59-66.
21. Thompson WD. Statistical analysis of case-control studies. Epidemiol Rev 1994;16:33-50.
22. Rothman KJ. Modern epidemiology. Boston, MA: Little, Brown & Co, 1986:311-26.
23. Cheng TJ, Christiani DC, Xu X, et al. Glutathione S-transferase mu genotype, diet, and smoking as determinants of sister chromatid exchange frequency in lymphocytes. Cancer Epidemiol Biomarkers Prev 1995;4:535-42.