Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord

Development (Cambridge)

Volumn 141, Issue 1, 2014, Pages 187-198

  Misra, Kamana ^a   Luo, Huijun ^a,d   Li, Shengguo ^a   Matise, Michael ^b   Xiang, Mengqing ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d MAYO GRADUATE SCHOOL   (United States)

Author keywords

Ascl1; bHLH proneural factor; BMP TGF ; Chick; Dll4 Notch; Foxn4; Mouse; Spinal cord; V2 interneuron

Indexed keywords

BMP PROTEIN; DLL4 PROTEIN; FOXN4 PROTEIN; HELIX LOOP HELIX PROTEIN; PROTEIN; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR MASH1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; GEL MOBILITY SHIFT ASSAY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERNEURON; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPINAL CORD;

ASCL1; BHLH PRONEURAL FACTOR; BMP/TGFΒ; CHICK; DLL4-NOTCH; FOXN4; MOUSE; SPINAL CORD; V2 INTERNEURON;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; CHICK EMBRYO; EYE PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERNEURONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; RECEPTORS, NOTCH; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPINAL CORD; TRANSFORMING GROWTH FACTOR BETA;

EID: 84890465598     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.092536     Document Type: Article

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