GATA2 is required for the generation of V2 interneurons

Development

Volumn 127, Issue 17, 2000, Pages 3829-3838

  Zhou, Y ^a   Yamamoto, M ^a   Engel, J D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

GATA2; Transgenic mice; V2 interneuron

Indexed keywords

CELL MARKER; TRANSCRIPTION FACTOR GATA 2;

ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CELL POPULATION; CELL TYPE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE INSERTION; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HYPOTHESIS; INTERNEURON; INTRON; MOUSE; MUTANT; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SPINAL CORD; TISSUE SPECIFICITY; UROGENITAL SYSTEM;

ANIMAL; BASE SEQUENCE; BRAIN; CENTRAL NERVOUS SYSTEM; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION; HUMAN; INTERNEURONS; INTRONS; MICE; MITOSIS; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; SPINAL CORD; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0033829599     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner
2. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
3. PAX2 is expressed in multiple spinal cord interneurons, including a population of EN 1 + interneurons that require PAX6 for their development
4. Reciprocal interactions of Pit 1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types
5. Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity
6. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
7. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
8. Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system
9. Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus
10. Olf-1-binding site: Characterization of an olfactory neuron-specific promoter motif
11. Expression of the chicken GATA factor family during early erythroid development and differentiation
12. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
13. Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements
14. Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants
15. Alternative promoters regulate transcription of the mouse GATA-2 gene
16. Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system
17. Neurogenesis in spinal cord of mouse: An autoradiographic analysis
18. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis
19. The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere. 4
20. A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord
21. Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene
22. Specification of motor neuron identity by the MNR2 homeodomain protein
23. An early haematopoietic defect in mice lacking the transcription factor GATA-2
24. Activity and tissue-specific expression of the transcription factor NF-E1 [GATA] multigene family
25. Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development