메뉴 건너뛰기




Volumn 191, Issue 12, 2013, Pages 5840-5847

AID and caspase 8 shape the germinal center response through apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CASPASE 8; DNA;

EID: 84890381835     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301776     Document Type: Article
Times cited : (14)

References (42)
  • 1
    • 34548036949 scopus 로고    scopus 로고
    • Germinal-center organization and cellular dynamics
    • Allen, C. D., T. Okada, and J. G. Cyster. 2007. Germinal-center organization and cellular dynamics. Immunity 27: 190-202.
    • (2007) Immunity , vol.27 , pp. 190-202
    • Allen, C.D.1    Okada, T.2    Cyster, J.G.3
  • 4
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102: 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 6
    • 0035910760 scopus 로고    scopus 로고
    • FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis
    • Hennino, A., M. Bérard, P. H. Krammer, and T. Defrance. 2001. FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis. J. Exp. Med. 193: 447-458.
    • (2001) J. Exp. Med. , vol.193 , pp. 447-458
    • Hennino, A.1    Bérard, M.2    Krammer, P.H.3    Defrance, T.4
  • 7
    • 0035655903 scopus 로고    scopus 로고
    • Death-receptor contribution to the germinal-center reaction
    • van Eijk, M., T. Defrance, A. Hennino, and C. de Groot. 2001. Death-receptor contribution to the germinal-center reaction. Trends Immunol. 22: 677-682.
    • (2001) Trends Immunol. , vol.22 , pp. 677-682
    • Van Eijk, M.1    Defrance, T.2    Hennino, A.3    De Groot, C.4
  • 8
    • 0029589915 scopus 로고
    • FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen
    • Smith, K. G., G. J. Nossal, and D. M. Tarlinton. 1995. FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen. Proc. Natl. Acad. Sci. USA 92: 11628-11632.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11628-11632
    • Smith, K.G.1    Nossal, G.J.2    Tarlinton, D.M.3
  • 9
    • 0035099037 scopus 로고    scopus 로고
    • Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
    • Takahashi, Y., H. Ohta, and T. Takemori. 2001. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. Immunity 14: 181-192.
    • (2001) Immunity , vol.14 , pp. 181-192
    • Takahashi, Y.1    Ohta, H.2    Takemori, T.3
  • 10
    • 0034253338 scopus 로고    scopus 로고
    • Fas-mediated apoptosis eliminates B cells that acquire self-reactivity during the germinal center response to NP
    • Hoch, S., M. Boyd, B. Malone, G. Gonye, J. Schwaber, and J. Schwaber. 2000. Fas-mediated apoptosis eliminates B cells that acquire self-reactivity during the germinal center response to NP. Cell. Immunol. 203: 103-110.
    • (2000) Cell. Immunol. , vol.203 , pp. 103-110
    • Hoch, S.1    Boyd, M.2    Malone, B.3    Gonye, G.4    Schwaber, J.5    Schwaber, J.6
  • 11
    • 0037496129 scopus 로고    scopus 로고
    • The control of apoptosis in lymphocyte selection
    • Strasser, A., and P. Bouillet. 2003. The control of apoptosis in lymphocyte selection. Immunol. Rev. 193: 82-92.
    • (2003) Immunol. Rev. , vol.193 , pp. 82-92
    • Strasser, A.1    Bouillet, P.2
  • 12
    • 0037633932 scopus 로고    scopus 로고
    • Apoptosis: Programmed cell death at a molecular level
    • Schultz, D. R., and W. J. Harrington, Jr. 2003. Apoptosis: programmed cell death at a molecular level. Semin. Arthritis Rheum. 32: 345-369.
    • (2003) Semin. Arthritis Rheum. , vol.32 , pp. 345-369
    • Schultz, D.R.1    Harrington Jr., W.J.2
  • 13
    • 79951839241 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunities
    • Zaheen, A., and A. Martin. 2011. Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunities. Am. J. Pathol. 178: 462-471.
    • (2011) Am. J. Pathol. , vol.178 , pp. 462-471
    • Zaheen, A.1    Martin, A.2
  • 15
    • 70149094600 scopus 로고    scopus 로고
    • AID constrains germinal center size by rendering B cells susceptible to apoptosis
    • Zaheen, A., B. Boulianne, J. Y. Parsa, S. Ramachandran, J. L. Gommerman, and A. Martin. 2009. AID constrains germinal center size by rendering B cells susceptible to apoptosis. Blood 114: 547-554.
    • (2009) Blood , vol.114 , pp. 547-554
    • Zaheen, A.1    Boulianne, B.2    Parsa, J.Y.3    Ramachandran, S.4    Gommerman, J.L.5    Martin, A.6
  • 16
    • 0034818310 scopus 로고    scopus 로고
    • Testing the reverse transcriptase model of somatic mutation
    • Sack, S. Z., P. D. Bardwell, and M. D. Scharff. 2001. Testing the reverse transcriptase model of somatic mutation. Mol. Immunol. 38: 303-311.
    • (2001) Mol. Immunol. , vol.38 , pp. 303-311
    • Sack, S.Z.1    Bardwell, P.D.2    Scharff, M.D.3
  • 18
    • 67649204698 scopus 로고    scopus 로고
    • CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells
    • Caron, G., S. Le Gallou, T. Lamy, K. Tarte, and T. Fest. 2009. CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells. J. Immunol. 182: 7595-7602.
    • (2009) J. Immunol. , vol.182 , pp. 7595-7602
    • Caron, G.1    Le Gallou, S.2    Lamy, T.3    Tarte, K.4    Fest, T.5
  • 20
    • 0026533967 scopus 로고
    • Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice
    • Mason, D. Y., M. Jones, and C. C. Goodnow. 1992. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. Int. Immunol. 4: 163-175.
    • (1992) Int. Immunol. , vol.4 , pp. 163-175
    • Mason, D.Y.1    Jones, M.2    Goodnow, C.C.3
  • 22
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma, S., B. P. Chen, M. Murphy, A. Kurimasa, and D. J. Chen. 2001. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276: 42462-42467.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 23
    • 34249790004 scopus 로고    scopus 로고
    • Molecular mechanisms of antibody somatic hypermutation
    • Di Noia, J. M., and M. S. Neuberger. 2007. Molecular mechanisms of antibody somatic hypermutation. Annu. Rev. Biochem. 76: 1-22.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 1-22
    • Di Noia, J.M.1    Neuberger, M.S.2
  • 24
    • 6344256944 scopus 로고    scopus 로고
    • Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
    • Rada, C., J. M. Di Noia, and M. S. Neuberger. 2004. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 16: 163-171.
    • (2004) Mol. Cell , vol.16 , pp. 163-171
    • Rada, C.1    Di Noia, J.M.2    Neuberger, M.S.3
  • 25
    • 24744459035 scopus 로고    scopus 로고
    • Cutting edge: Innate immunity conferred by B cells is regulated by caspase-8
    • Beisner, D. R., I. L. Ch'en, R. V. Kolla, A. Hoffmann, and S. M. Hedrick. 2005. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. J. Immunol. 175: 3469-3473.
    • (2005) J. Immunol. , vol.175 , pp. 3469-3473
    • Beisner, D.R.1    Ch'En, I.L.2    Kolla, R.V.3    Hoffmann, A.4    Hedrick, S.M.5
  • 27
    • 0019442186 scopus 로고
    • Heavy chain variable region contribution to the NPb family of antibodies: Somatic mutation evident in a gamma 2a variable region
    • Bothwell, A. L., M. Paskind, M. Reth, T. Imanishi-Kari, K. Rajewsky, and D. Baltimore. 1981. Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region. Cell 24: 625-637.
    • (1981) Cell , vol.24 , pp. 625-637
    • Bothwell, A.L.1    Paskind, M.2    Reth, M.3    Imanishi-Kari, T.4    Rajewsky, K.5    Baltimore, D.6
  • 28
    • 0003575039 scopus 로고
    • Stepwise intraclonal maturation of antibody affinity through somatic hypermutation
    • Kocks, C., and K. Rajewsky. 1988. Stepwise intraclonal maturation of antibody affinity through somatic hypermutation. Proc. Natl. Acad. Sci. USA 85: 8206-8210.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8206-8210
    • Kocks, C.1    Rajewsky, K.2
  • 29
    • 0025726702 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
    • Jacob, J., R. Kassir, and G. Kelsoe. 1991. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173: 1165-1175.
    • (1991) J. Exp. Med. , vol.173 , pp. 1165-1175
    • Jacob, J.1    Kassir, R.2    Kelsoe, G.3
  • 30
    • 0026670190 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
    • Jacob, J., and G. Kelsoe. 1992. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. J. Exp. Med. 176: 679-687.
    • (1992) J. Exp. Med. , vol.176 , pp. 679-687
    • Jacob, J.1    Kelsoe, G.2
  • 32
    • 84874195262 scopus 로고    scopus 로고
    • The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells
    • Koncz, G., and A. O. Hueber. 2012. The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells. Front. Immunol. 3: 207.
    • (2012) Front. Immunol. , vol.3 , pp. 207
    • Koncz, G.1    Hueber, A.O.2
  • 34
    • 84861688429 scopus 로고    scopus 로고
    • Determining germinal centre B cell fate
    • Zotos, D., and D. M. Tarlinton. 2012. Determining germinal centre B cell fate. Trends Immunol. 33: 281-288.
    • (2012) Trends Immunol. , vol.33 , pp. 281-288
    • Zotos, D.1    Tarlinton, D.M.2
  • 35
    • 0029788298 scopus 로고    scopus 로고
    • Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice
    • Livák, F., S. C. Welsh, C. J. Guidos, I. N. Crispe, J. S. Danska, and D. G. Schatz. 1996. Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice. J. Exp. Med. 184: 419-428.
    • (1996) J. Exp. Med. , vol.184 , pp. 419-428
    • Livák, F.1    Welsh, S.C.2    Guidos, C.J.3    Crispe, I.N.4    Danska, J.S.5    Schatz, D.G.6
  • 36
    • 0035160129 scopus 로고    scopus 로고
    • Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors
    • Williams, C. J., I. Grandal, D. J. Vesprini, U. Wojtyra, J. S. Danska, and C. J. Guidos. 2001. Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors. Mol. Cell. Biol. 21: 400-413.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 400-413
    • Williams, C.J.1    Grandal, I.2    Vesprini, D.J.3    Wojtyra, U.4    Danska, J.S.5    Guidos, C.J.6
  • 37
    • 0036171910 scopus 로고    scopus 로고
    • Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory
    • Martin, S. W., and C. C. Goodnow. 2002. Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory. Nat. Immunol. 3: 182-188.
    • (2002) Nat. Immunol. , vol.3 , pp. 182-188
    • Martin, S.W.1    Goodnow, C.C.2
  • 38
    • 34247340435 scopus 로고    scopus 로고
    • Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors
    • Horikawa, K., S. W. Martin, S. L. Pogue, K. Silver, K. Peng, K. Takatsu, and C. C. Goodnow. 2007. Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors. J. Exp. Med. 204: 759-769.
    • (2007) J. Exp. Med. , vol.204 , pp. 759-769
    • Horikawa, K.1    Martin, S.W.2    Pogue, S.L.3    Silver, K.4    Peng, K.5    Takatsu, K.6    Goodnow, C.C.7
  • 40
    • 70349249529 scopus 로고    scopus 로고
    • Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts
    • Chan, T. D., D. Gatto, K. Wood, T. Camidge, A. Basten, and R. Brink. 2009. Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts. J. Immunol. 183: 3139-3149.
    • (2009) J. Immunol. , vol.183 , pp. 3139-3149
    • Chan, T.D.1    Gatto, D.2    Wood, K.3    Camidge, T.4    Basten, A.5    Brink, R.6
  • 41
    • 33750502877 scopus 로고    scopus 로고
    • High affinity germinal center B cells are actively selected into the plasma cell compartment
    • Phan, T. G., D. Paus, T. D. Chan, M. L. Turner, S. L. Nutt, A. Basten, and R. Brink. 2006. High affinity germinal center B cells are actively selected into the plasma cell compartment. J. Exp. Med. 203: 2419-2424.
    • (2006) J. Exp. Med. , vol.203 , pp. 2419-2424
    • Phan, T.G.1    Paus, D.2    Chan, T.D.3    Turner, M.L.4    Nutt, S.L.5    Basten, A.6    Brink, R.7
  • 42
    • 38049110981 scopus 로고    scopus 로고
    • Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration
    • Kuchen, S., R. Robbins, G. P. Sims, C. Sheng, T. M. Phillips, P. E. Lipsky, and R. Ettinger. 2007. Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. J. Immunol. 179: 5886-5896.
    • (2007) J. Immunol. , vol.179 , pp. 5886-5896
    • Kuchen, S.1    Robbins, R.2    Sims, G.P.3    Sheng, C.4    Phillips, T.M.5    Lipsky, P.E.6    Ettinger, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.