Mitochondrial dysfunction in brain cortex mitochondria of STZ-diabetic rats: Effect of l-arginine

Neurochemical Research

Volumn 38, Issue 12, 2013, Pages 2570-2580

  Ortiz, M Del Carmen ^a   Lores Arnaiz, Silvia ^a   Albertoni Borghese, M Florencia ^a   Balonga, Sabrina ^a   Lavagna, Agustina ^a   Filipuzzi, Ana Laura ^a   Cicerchia, Daniela ^a   Majowicz, Monica ^a   Bustamante, Juanita ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Brain cortex mitochondria; Diabetes; l Arginine; Mitochondrial respiration; Nitric oxide

Indexed keywords

ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN CORTEX; CONTROLLED STUDY; DEPOLARIZATION; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; LIPID PEROXIDATION; MALE; MITOCHONDRIAL DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPOLARIZATION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS;

RATTUS;

ANIMALS; ARGININE; BLOOD GLUCOSE; BLOTTING, WESTERN; BODY WEIGHT; CEREBRAL CORTEX; DIABETES MELLITUS, EXPERIMENTAL; LIPID PEROXIDATION; MALE; MITOCHONDRIA; NITRIC OXIDE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; STREPTOZOCIN;

EID: 84890313544     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1172-3     Document Type: Article

References (48)

1. Mastrocola R, Restivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, Boccuzzi G (2005) Oxidative and nitrosative stress in brain mitochondria of diabetic rats. J Endocrinol 187:37-44
2. Cardoso S, Santos MS, Seica R, Moreira PI (2010) Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. Biochim Biophys Acta 1802:942-951
3. Moreira PI, Santos MS, Moreno AM, Proenca T, Seica R, Oliveira CR (2004) Effect of streptozotocin-induced diabetes on rat brain mitochondria. J Neuroendocrinol 16:32-38
4. Languren G, Montiel T, Julio-Amilpas A, Massieu L (2013) Neuronal damage and cognitive impairment associated with hypoglycemia: an integrated view. Neurochem Int 63:331-343
5. Raza H, Prabu SK, John A, Avadhani NG (2011) Impaired mitochondrial respiratory functions and oxidative stress in streptozotocin-induced diabetic rats. Int J Mol Sci 12:3133-3147
6. Prasath GS, Subramanian SP (2013) Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats. Food Chem Toxicol 59:249-255
7. Raha S, Robinson BH (2000) Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25:502-508
8. Duchen MR (2004) Roles of mitochondria in health and disease. Diabetes 53(Suppl 1):S96-S102
9. Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404:787-790
10. Di Lisa F, Kaludercic N, Carpi A, Menabo R, Giorgio M (2009) Mitochondria and vascular pathology. Pharmacol Rep 61:123-130
11. Knowles RG, Moncada S (1994) Nitric oxide synthases in mammals. Biochem J 298(Pt 2):249-258
12. Brown GC, Cooper CE (1994) Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 356:295-298
13. Forstermann U (2006) Endothelial NO synthase as a source of NO and superoxide. Eur J Clin Pharmacol 62:5-12
14. Rains JL, Jain SK (2011) Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med 50:567-575
15. Ren XY, Li YN, Qi JS, Niu T (2008) Peroxynitrite-induced protein nitration contributes to liver mitochondrial damage in diabetic rats. J Diabetes Complicat 22:357-364
16. El-Missiry MA, Othman AI, Amer MA (2004) l-Arginine ameliorates oxidative stress in alloxan-induced experimental diabetes mellitus. J Appl Toxicol 24:93-97
17. Vasilijevic A, Buzadzic B, Korac A, Petrovic V, Jankovic A, Korac B (2007) Beneficial effects of l-arginine nitric oxide-producing pathway in rats treated with alloxan. J Physiol 584:921-933
18. Kawano H, Motoyama T, Hirai N, Kugiyama K, Yasue H, Ogawa H (2002) Endothelial dysfunction in hypercholesterolemia is improved by l-arginine administration: possible role of oxidative stress. Atherosclerosis 161:375-380
19. Munusamy S, Millan-Crow LA (2009) Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells. Free Radic Biol Med 46:1149-1157
20. Lee DL, Sasser JM, Hobbs JL, Boriskie A, Pollock DM, Carmines PK, Pollock JS (2005) Posttranslational regulation of NO synthase activity in the renal medulla of diabetic rats. Am J Physiol Renal Physiol 288:F82-F90
21. Kato T, Yamashita T, Sekiguchi A, Tsuneda T, Sagara K, Takamura M, Kaneko S, Aizawa T, Fu LT (2011) Angiotensin II type 1 receptor blocker attenuates diabetes-induced atrial structural remodeling. J Cardiol 58:131-136
22. Becher PM, Lindner D, Frohlich M, Savvatis K, Westermann D, Tschope C (2013) Assessment of cardiac inflammation and remodeling during the development of streptozotocin-induced diabetic cardiomyopathy in vivo: a time course analysis. Int J Mol Med 32:158-164
23. Popov D, Costache G, Georgescu A, Enache M (2002) Beneficial effects of l-arginine supplementation in experimental hyperlipemia-hyperglycemia in the hamster. Cell Tissue Res 308:109-120
24. Ohta Y, Nishida K (2001) Protective effect of l-arginine against stress-induced gastric mucosal lesions in rats and its relation to nitric oxide-mediated inhibition of neutrophil infiltration. Pharmacol Res 43:535-541
25. Yagi K (1976) A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 15:212-216
26. Esterbauer H, Cheeseman KH, Dianzani MU, Poli G, Slater TF (1982) Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2 + in rat liver microsomes. Biochem J 208:129-140
27. Arnaiz SL, Coronel MF, Boveris A (1999) Nitric oxide, superoxide, and hydrogen peroxide production in brain mitochondria after haloperidol treatment. Nitric Oxide 3:235-243
28. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
29. Boveris A, Arnaiz SL, Bustamante J, Alvarez S, Valdez L, Boveris AD, Navarro A (2002) Pharmacological regulation of mitochondrial nitric oxide synthase. Methods Enzymol 359:328-339
30. Estabrook RW (1967) Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios. Meth Enzymol 10:41-47
31. Chance B, Williams GR (1956) The respiratory chain and oxidative phosphorylation. Adv Enzymol 17:65-134
32. Bustamante J, Czerniczyniec A, Cymeryng C, Lores-Arnaiz S (2008) Age related changes from youth to adulthood in rat brain cortex: nitric oxide synthase and mitochondrial respiratory function. Neurochem Res 33:1216-1223
33. Boveris A (1984) Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Methods Enzymol 105:429-435
34. Bustamante J, Di Libero E, Fernandez-Cobo M, Monti N, Cadenas E, Boveris A (2004) Kinetic analysis of thapsigargin-induced thymocyte apoptosis. Free Radic Biol Med 37:1490-1498
35. Weissbach H, Smith TE, Daly JW, Witkop B, Udenfriend S (1960) A rapid spectrophotometric assay of mono-amine oxidase based on the rate of disappearance of kynuramine. J Biol Chem 235:1160-1163
36. Murphy ME, Noack E (1994) Nitric oxide assay using hemoglobin method. Methods Enzymol 233:240-250
37. Carre M, Andre N, Carles G, Borghi H, Brichese L, Briand C, Braguer D (2002) Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel. J Biol Chem 277:33664-33669
38. Oberley LW (1988) Free radicals and diabetes. Free Radic Biol Med 5:113-124
39. Chowdhury SK, Zherebitskaya E, Smith DR, Akude E, Chattopadhyay S, Jolivalt CG, Calcutt NA, Fernyhough P (2010) Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment. Diabetes 59:1082-1091
40. Flarsheim CE, Grupp IL, Matlib MA (1996) Mitochondrial dysfunction accompanies diastolic dysfunction in diabetic rat heart. Am J Physiol 271:H192-H202
41. Fernyhough P, Roy Chowdhury SK, Schmidt RE (2010) Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Rev Endocrinol Metab 5:39-49
42. Mayanil CS, Kazmi SM, Baquer NZ (1982) Changes in monoamine oxidase activity in rat brain during alloxan diabetes. J Neurochem 38:179-183
43. Yu WJ, Juang SW, Chin WT, Chi TC, Wu TJ, Cheng JT (1999) Decrease of nitric oxide synthase in the cerebrocortex of streptozotocin-induced diabetic rats. Neurosci Lett 272:99-102
44. El-Hattab AW, Emrick LT, Craigen WJ, Scaglia F (2012) Citrulline and arginine utility in treating nitric oxide deficiency in mitochondrial disorders. Mol Genet Metab 107:247-252
45. Chen N, Leng YP, Xu WJ, Luo JD, Chen MS, Xiong Y (2011) Contribution of endogenous inhibitor of nitric oxide synthase to hepatic mitochondrial dysfunction in streptozotocin-induced diabetic rats. Cell Physiol Biochem 27:341-352
46. Boger RH (2004) Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the "l-arginine paradox" and acts as a novel cardiovascular risk factor. J Nutr 134:2842S-2847S
47. Lind KR, Ball KK, Cruz NF, Dienel GA (2013) The unfolded protein response to endoplasmic reticulum stress in cultured astrocytes and rat brain during experimental diabetes. Neurochem Int 62:784-795
48. Gandhi GK, Ball KK, Cruz NF, Dienel GA (2010) Hyperglycaemia and diabetes impair gap junctional communication among astrocytes. ASN Neuro 2:e00030