Contribution of endogenous inhibitor of nitric oxide synthase to hepatic mitochondrial dysfunction in streptozotocin-induced diabetic rats

Cellular Physiology and Biochemistry

Volumn 27, Issue 3-4, 2011, Pages 341-352

  Chen, Na ^b   Leng, Yi Ping ^b   Xu, Wen Juan ^b   Luo, Jian Dong ^a   Chen, Min Sheng ^a   Xiong, Yan ^a,b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Asymmetric dimethylarginine; Diabetes mellitus; Liver; Mitochondrial biogenesis; Mitochondrial dysfunction; Nitric oxide; Oxidative stress; Uncoupling protein 2

Indexed keywords

ADENOSINE TRIPHOSPHATE; MALONALDEHYDE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PYRROLIDINE DITHIOCARBAMATE; SUPEROXIDE DISMUTASE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CONTROLLED STUDY; COPY NUMBER VARIATION; DIABETES MELLITUS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; LIVER CELL; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL GENE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

RATTUS;

EID: 79953777985     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000327960     Document Type: Article

References (38)

1. Lowell BB, Shulman GI: Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387. (Pubitemid 40139974)
2. Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI: Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest 2005;115:3587-3593. (Pubitemid 43121847)
3. Musatov A, Ortega-Lopez J, Robinson NC: Detergent-solubilized bovine cytochrome c oxidase: dimerization depends on the amphiphilic environment. Biochemistry 2000;39:12996-3004.
4. Kelley DE, He J, Menshikova EV, Ritov VB: Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002;51:2944-2950.
5. Masayesva BG, Mambo E, Taylor RJ, Goloubeva OG, Zhou S, Cohen Y, Minhas K, Koch W, Sciubba J, Alberg AJ, Sidransky D, Califano J: Mitochondrial DNA content increase in response to cigarette smoking. Cancer Epidemiol Biomarkers Prev 2006;15:19-24.
6. Choo HJ, Kim JH, Kwon OB, Lee CS, Mun JY, Han SS, Yoon YS, Yoon G, Choi KM, Ko YG: Mitochondria are impaired in the adipocytes of type 2 diabetic mice. Diabetologia 2006;49:784-791. (Pubitemid 43361881)
7. Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, Vidal H, Rieusset J: Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J Clin Invest 2008;118:789-800. (Pubitemid 351206566)
8. Mariappan N, Elks CM, Sriramula S, Guggilam A, Liu Z, Borkhsenious O, Francis J: NF-{kappa}B-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes. Cardiovasc Res 2010;85:473-483.
9. Chan CB, De Leo D, Joseph JW, McQuaid TS, Ha XF, Xu F, Tsushima RG, Pennefather PS, Salapatek AM, Wheeler MB: Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action. Diabetes 2001;50:1302-1310. (Pubitemid 32500162)
10. Lee FY, Li Y, Zhu H, Yang S, Lin HZ, Trush M, Diehl AM: Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. Hepatology 1999;29:677-687. (Pubitemid 29109580)
11. Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP: Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 2000;106:847-856.
12. Brown GC: Cell biology. NO says yes to mitochondria. Science 2003;299:838-9.
13. Boger RH, Bode-Boger SM, Tsao PS, Lin PS, Chan JR, Cooke JP: An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes. J Am Coll Cardiol 2000;36:2287-2295.
14. Stuhlinger MC, Abbasi F, Chu JW, Lamendola C, McLaughlin TL, Cooke JP, Reaven GM, Tsao PS: Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA 2002;287:1420-1426. (Pubitemid 34250505)
15. Xiong Y, Fu YF, Fu SH, Zhou HH: Elevated levels of the serum endogenous inhibitor of nitric oxide synthase and metabolic control in rats with streptozotocin-induced diabetes. J Cardiovasc Pharmacol 2003;42:191-196. (Pubitemid 36899670)
16. Lin KY, Ito A, Asagami T, Tsao PS, Adimoolam S, Kimoto M, Tsuji H, Reaven GM, Cooke JP: Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethyl-arginine and dimethylarginine dimethyl-aminohydrolase. Circulation 2002;106:987-992. (Pubitemid 34925335)
17. Xiong Y, Lu R, Li YJ, Deng HW: Elevation of an endogenous inhibitor of nitric oxide synthase in diabetic rat serum. Acta Pharmacol Sin 1997;18:511-514. (Pubitemid 27473885)
18. Siroen MP, van der Sijp JR, Teerlink T, van Schaik C, Nijveldt RJ, van Leeuwen PA: The human liver clears both asymmetric and symmetric dimethylarginine. Hepatology 2005;41:559-565. (Pubitemid 40289503)
19. Yin QF, Fu SH, He P, Xiong Y: Dimethyl-arginine dimethylaminohydrolase inhibition and asymmetric dimethyl-arginine accumulation contribute to endothelial dysfunction in rats exposed to glycosylated protein: effects of aminoguanidine. Atherosclerosis 2007;190:53-61. (Pubitemid 44908321)
20. Kawamura-Sato K, Hirama Y, Agata N, Ito H, Torii K, Takeno A, Hasegawa T, Shimomura Y, Ohta M: Quantitative analysis of cereulide, an emetic toxin of Bacillus cereus, by using rat liver mitochondria. Microbiol Immunol 2005;49:25-30. (Pubitemid 40313116)
21. Akao Y, Otsuki Y, Kataoka S, Ito Y, Tsujimoto Y: Multiple subcellular localization of bcl-2: detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes. Cancer Res 1994;54:2468-2471. (Pubitemid 24138742)
22. Munujos P, Coll-Canti J, Gonzalez-Sastre F, Gella FJ: Assay of succinate dehydrogenase activity by a colorimetric-continuous method using iodonitrotetrazolium chloride as electron acceptor. Anal Biochem 1993;212:506-509. (Pubitemid 23245103)
23. Morin C, Zini R, Simon N, Tillement JP: Dehydroepiandrosterone and alpha-estradiol limit the functional alterations of rat brain mitochondria submitted to different experimental stresses. Neuroscience 2002;115:415-424. (Pubitemid 35284758)
24. Boveris A, Valdez LB, Zaobornyj T, Bustamante J: Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol. Biochim Biophys Acta 2006;1757:535-542. (Pubitemid 43993837)
25. Drew B, Leeuwenburgh C: Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction. Am J Physiol Regul Integr Comp Physiol 2003;285:R1259-267.
26. Yagi K: A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 1976;15:212-216.
27. Feng M, Liu L, Guo Z, Xiong Y: Gene transfer of dimethylarginine dimethyl-aminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine. Eur J Pharmacol 2008;584:49-56.
28. Krzyzanowska K, Mittermayer F, Wolzt M, Schernthaner G: Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes. Diabetes Care 2007;30:1834-1839. (Pubitemid 47036360)
29. Xiong Y, Lei M, Fu S, Fu Y: Effect of diabetic duration on serum concentrations of endogenous inhibitor of nitric oxide synthase in patients and rats with diabetes. Life Sci 2005;77:149-159. (Pubitemid 40603500)
30. Hong L, Fast W: Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia. J Biol Chem 2007;282:34684-34692. (Pubitemid 350232428)
31. Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI: Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes 2007;56:1376-1381. (Pubitemid 46715630)
32. Wu D, Cederbaum A: Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity. Toxicol Appl Pharmacol 2006;216:282-292. (Pubitemid 44466008)
33. Schild L, Jaroscakova I, Lendeckel U, Wolf G, Keilhoff G: Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism. FASEB J 2006;20:145-147. (Pubitemid 43100495)
34. Chavin KD, Yang S, Lin HZ, Chatham J, Chacko VP, Hoek JB, Walajtys-Rode E, Rashid A, Chen CH, Huang CC, Wu TC, Lane MD, Diehl AM: Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 1999;274:5692-5700. (Pubitemid 29109222)
35. Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB: Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 2001;105:745-755. (Pubitemid 32635104)
36. Palmeira CM, Rolo AP, Berthiaume J, Bjork JA, Wallace KB: Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. Toxicol Appl Pharmacol 2007;225:214-220. (Pubitemid 350088064)
37. Schrauwen P, Hesselink MK: Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. Diabetes 2004;53:1412-1417. (Pubitemid 38697650)
38. Stosic-Grujicic SD, Miljkovic DM, Cvetkovic ID, Maksimovic-Ivanic DD, Trajkovic V: Immunosuppressive and anti-inflammatory action of antioxidants in rat autoimmune diabetes. J Autoimmun 2004;22:267-276. (Pubitemid 38548857)