Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice

Particle and Fibre Toxicology

Volumn 10, Issue 1, 2013, Pages

  Oppenheim, Hannah A ^a   Lucero, JoAnn ^a,d   Guyot, Anne Cécile ^b   Herbert, Lindsay M ^c   McDonald, Jacob D ^a   Mabondzo, Aloïse ^b   Lund, Amie K ^a,d  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b CEA SACLAY   (France)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Air pollution; Blood brain barrier; Matrix metalloproteinase; Neuroinflammation; Tight junction proteins

Indexed keywords

APOLIPOPROTEIN E; BIOLOGICAL MARKER; CLAUDIN 5; GELATINASE A; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MULTIDRUG RESISTANCE PROTEIN; OCCLUDIN; TIGHT JUNCTION PROTEIN;

AIR POLLUTANT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CULTURE; BRAIN BLOOD VESSEL; COCULTURE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; ENZYME ACTIVITY; EXHAUST GAS; IN VITRO STUDY; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEWBORN; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALIA; MUS;

ANIMALS; APOLIPOPROTEINS E; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; INHALATION EXPOSURE; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROGENIC INFLAMMATION; NEUROGLIA; P-GLYCOPROTEIN; TIGHT JUNCTION PROTEINS; VEHICLE EMISSIONS;

EID: 84890262292     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-10-62     Document Type: Article

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