메뉴 건너뛰기




Volumn 13, Issue , 2013, Pages

Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase

Author keywords

3 T3 L1 Preadipocytes; Fatty acid synthase; Grape skin extract; Inhibitor; Obesity; Resveratrol; ketoacyl reductase

Indexed keywords

3 OXOACYL REDUCTASE; ACETIC ACID ETHYL ESTER; ACETYL COENZYME A; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; GRAPE SKIN EXTRACT; LIPID; MALONYL COENZYME A; OXIDOREDUCTASE; PLANT EXTRACT; RESVERATROL; UNCLASSIFIED DRUG;

EID: 84890257356     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-361     Document Type: Article
Times cited : (42)

References (47)
  • 3
    • 33845996547 scopus 로고    scopus 로고
    • Obesity, high energy intake, lack of physical activity and the risk of kidney cancer
    • Pan SY, Desmeules M, Morrison H, Wen SW. Obesity, high energy intake, lack of physical activity and the risk of kidney cancer. Cancer Epidemiol Biomarkers Prev 2006, 15:2453-2460.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 2453-2460
    • Pan, S.Y.1    Desmeules, M.2    Morrison, H.3    Wen, S.W.4
  • 4
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC. International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009, 120:1640-1645. International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5    Donato, K.A.6    Fruchart, J.C.7    James, W.P.8    Loria, C.M.9    Smith, S.C.10
  • 6
    • 79960452600 scopus 로고    scopus 로고
    • Metabolic syndrome: nature, therapeutic solutions and options
    • Onat A. Metabolic syndrome: nature, therapeutic solutions and options. Expert Opin Pharmacother 2011, 12:1887-1900.
    • (2011) Expert Opin Pharmacother , vol.12 , pp. 1887-1900
    • Onat, A.1
  • 7
    • 84865173624 scopus 로고    scopus 로고
    • Grape skin extract reduces adipogenesis- and lipogenesis-related gene expression in 3 T3-L1 adipocytes through the peroxisome proliferator-activated receptor-γ signaling pathway
    • Jeong YS, Hong JH, Cho KH, Jung HK. Grape skin extract reduces adipogenesis- and lipogenesis-related gene expression in 3 T3-L1 adipocytes through the peroxisome proliferator-activated receptor-γ signaling pathway. Nutr Res 2012, 32(7):514-521.
    • (2012) Nutr Res , vol.32 , Issue.7 , pp. 514-521
    • Jeong, Y.S.1    Hong, J.H.2    Cho, K.H.3    Jung, H.K.4
  • 8
    • 7044270592 scopus 로고    scopus 로고
    • Adipose tissue: new therapeutic targets from molecular and genetic studies-IASO stock conference 2003 report
    • Farmer SR, Auwerx J. Adipose tissue: new therapeutic targets from molecular and genetic studies-IASO stock conference 2003 report. Obes Rev 2004, 5:189-196.
    • (2004) Obes Rev , vol.5 , pp. 189-196
    • Farmer, S.R.1    Auwerx, J.2
  • 9
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: when tissues overeat
    • Schaffer JE. Lipotoxicity: when tissues overeat. Curr Opin Lipidol 2003, 14(3):281-287.
    • (2003) Curr Opin Lipidol , vol.14 , Issue.3 , pp. 281-287
    • Schaffer, J.E.1
  • 10
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger RH. Lipotoxic diseases. Annu Rev Med 2002, 53:319-336.
    • (2002) Annu Rev Med , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 11
    • 0035130102 scopus 로고    scopus 로고
    • Diseases of liporegulation: new perspective on obesity and related disorders
    • Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 2001, 15(2):312-321.
    • (2001) FASEB J , vol.15 , Issue.2 , pp. 312-321
    • Unger, R.H.1    Orci, L.2
  • 12
    • 33750217236 scopus 로고    scopus 로고
    • Lipotoxicity
    • Weinberg JM. Lipotoxicity. Kidney Int 2006, 70(9):1560-1566.
    • (2006) Kidney Int , vol.70 , Issue.9 , pp. 1560-1566
    • Weinberg, J.M.1
  • 13
    • 55249098186 scopus 로고    scopus 로고
    • White adipose tissue as endocrine organ and its role in obesity
    • Vazquez-Vela ME, Torres N, Tovar AR. White adipose tissue as endocrine organ and its role in obesity. Arch Med Res 2008, 39:715-728.
    • (2008) Arch Med Res , vol.39 , pp. 715-728
    • Vazquez-Vela, M.E.1    Torres, N.2    Tovar, A.R.3
  • 15
    • 0024315871 scopus 로고
    • Fatty acid synthase, a proficient multifunctional enzyme
    • Wakil SJ. Fatty acid synthase, a proficient multifunctional enzyme. Biochem 1989, 28:4523-4530.
    • (1989) Biochem , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 16
    • 0028557012 scopus 로고
    • The animal fatty acid synthase: one gene, one polypeptide, seven enzymes
    • Smith S. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J 1994, 8:1248-1259.
    • (1994) FASEB J , vol.8 , pp. 1248-1259
    • Smith, S.1
  • 17
    • 0026696804 scopus 로고
    • Genetic-regulation of fatty-acid synthetase expression in adipose tissue over transcription of the gene in genetically-obese rats
    • Guichard C, Dugail I, Leliepvre X, Lavau M. Genetic-regulation of fatty-acid synthetase expression in adipose tissue over transcription of the gene in genetically-obese rats. J Lipid Res 1992, 33:679-687.
    • (1992) J Lipid Res , vol.33 , pp. 679-687
    • Guichard, C.1    Dugail, I.2    Leliepvre, X.3    Lavau, M.4
  • 18
    • 0028815382 scopus 로고
    • Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty-acid synthetase promoter activities in transiently transfected adipocytes from geneticallyobese rats
    • Rolland V, Dugail I, Leliepvre X, Lavau M. Evidence of increased glyceraldehyde-3-phosphate dehydrogenase and fatty-acid synthetase promoter activities in transiently transfected adipocytes from geneticallyobese rats. J Biol Chem 1995, 270:1102-1106.
    • (1995) J Biol Chem , vol.270 , pp. 1102-1106
    • Rolland, V.1    Dugail, I.2    Leliepvre, X.3    Lavau, M.4
  • 20
    • 70349983259 scopus 로고    scopus 로고
    • Tannins: current knowledge of food sources, intake, bioavailability and biological effects
    • Serrano J, Puupponen-Pimiä R, Dauer A, Aura AM, Saura-Calixto F. Tannins: current knowledge of food sources, intake, bioavailability and biological effects. Mol Nutr Food Res 2009, 53(Suppl):310-329.
    • (2009) Mol Nutr Food Res , vol.53 , Issue.SUPPL , pp. 310-329
    • Serrano, J.1    Puupponen-Pimiä, R.2    Dauer, A.3    Aura, A.M.4    Saura-Calixto, F.5
  • 21
    • 74349097440 scopus 로고    scopus 로고
    • Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms
    • Bladé C, Arola L, Salvadó MJ. Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms. Mol Nutr Food Res 2010, 54(1):37-59.
    • (2010) Mol Nutr Food Res , vol.54 , Issue.1 , pp. 37-59
    • Bladé, C.1    Arola, L.2    Salvadó, M.J.3
  • 22
    • 51549102594 scopus 로고    scopus 로고
    • Multi-targeted prevention and therapy of cancer by proanthocyanidins
    • Nandakumar V, Singh T, Katiyar SK. Multi-targeted prevention and therapy of cancer by proanthocyanidins. Cancer Lett 2008, 269(2):378-387.
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 378-387
    • Nandakumar, V.1    Singh, T.2    Katiyar, S.K.3
  • 24
    • 79955440961 scopus 로고    scopus 로고
    • Grape skin improves antioxidant capacity in rats fed a high fat diet
    • Lee SJ, Choi SK, Seo JS. Grape skin improves antioxidant capacity in rats fed a high fat diet. Nutr Res Pract 2009, 3:279-285.
    • (2009) Nutr Res Pract , vol.3 , pp. 279-285
    • Lee, S.J.1    Choi, S.K.2    Seo, J.S.3
  • 25
    • 80055042812 scopus 로고    scopus 로고
    • Anti-obesity effect of grape skin extract in 3 T3-L1 adipocytes
    • Jeong YS, Jung HK, Cho KH, Hong JH. Anti-obesity effect of grape skin extract in 3 T3-L1 adipocytes. Food Sci Biotechnol 2011, 20:635-642.
    • (2011) Food Sci Biotechnol , vol.20 , pp. 635-642
    • Jeong, Y.S.1    Jung, H.K.2    Cho, K.H.3    Hong, J.H.4
  • 26
    • 33748322067 scopus 로고    scopus 로고
    • A review of the content of the putative chemopreventive phytoalexin resveratrol in red wine
    • Stervbo U, Vang O, Bonnesen C. A review of the content of the putative chemopreventive phytoalexin resveratrol in red wine. Food Chem 2007, 101(2):449-457.
    • (2007) Food Chem , vol.101 , Issue.2 , pp. 449-457
    • Stervbo, U.1    Vang, O.2    Bonnesen, C.3
  • 31
    • 0022244513 scopus 로고
    • Studies on the reactivity of the essential sulfhydryl groups as a conformational probe for the fatty acid synthetase of chicken liver: inactivation by 5, 5′-dithiobis-(2-nitrobenzoic acid) and intersubunit cross-linking of the inactivated enzyme
    • Tian WX, Hsu RY, Wang YS. Studies on the reactivity of the essential sulfhydryl groups as a conformational probe for the fatty acid synthetase of chicken liver: inactivation by 5, 5′-dithiobis-(2-nitrobenzoic acid) and intersubunit cross-linking of the inactivated enzyme. J Biol Chem 1985, 260:11375-11387.
    • (1985) J Biol Chem , vol.260 , pp. 11375-11387
    • Tian, W.X.1    Hsu, R.Y.2    Wang, Y.S.3
  • 32
    • 48649088595 scopus 로고    scopus 로고
    • A substitutive substrate for measurements of beta-ketoacyl reductases in two fatty acid synthase systems
    • Sun YH, Cheng Q, Tian WX, Wu XD. A substitutive substrate for measurements of beta-ketoacyl reductases in two fatty acid synthase systems. J Biochem Biophys Methods 2008, 70(6):850-856.
    • (2008) J Biochem Biophys Methods , vol.70 , Issue.6 , pp. 850-856
    • Sun, Y.H.1    Cheng, Q.2    Tian, W.X.3    Wu, X.D.4
  • 33
    • 0035900577 scopus 로고    scopus 로고
    • Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase
    • Wang X, Tian WX. Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase. Biochem Biophys Res Commun 2001, 288:1200-1206.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 1200-1206
    • Wang, X.1    Tian, W.X.2
  • 34
    • 0242298292 scopus 로고    scopus 로고
    • The galloyl moiety of green tea catechins is critical structural feature to inhibit fatty-acid synthase
    • Wang X, Song KH, Guo QX, Tian WX. The galloyl moiety of green tea catechins is critical structural feature to inhibit fatty-acid synthase. Biochem Pharmacol 2003, 66:2039-2047.
    • (2003) Biochem Pharmacol , vol.66 , pp. 2039-2047
    • Wang, X.1    Song, K.H.2    Guo, Q.X.3    Tian, W.X.4
  • 36
    • 30344471085 scopus 로고    scopus 로고
    • Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site
    • Zhang R, Xiao W, Wang X, Wu X, Tian W. Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site. Biotechnol Appl Biochem 2006, 43:1-7.
    • (2006) Biotechnol Appl Biochem , vol.43 , pp. 1-7
    • Zhang, R.1    Xiao, W.2    Wang, X.3    Wu, X.4    Tian, W.5
  • 37
    • 32944475076 scopus 로고    scopus 로고
    • Structure-activity relationship of polyphenols that inhibit fatty acid synthase
    • Li BH, Ma XF, Wang Y, Tian WX. Structure-activity relationship of polyphenols that inhibit fatty acid synthase. J Biochem (Tokyo) 2005, 138(6):679-685.
    • (2005) J Biochem (Tokyo) , vol.138 , Issue.6 , pp. 679-685
    • Li, B.H.1    Ma, X.F.2    Wang, Y.3    Tian, W.X.4
  • 39
    • 0037219918 scopus 로고    scopus 로고
    • Antiproliferative effect of antioxidant polyphenols from grape in murine Hepa-1c1c7
    • Matito C, Mastorakou F, Centelles JJ, Torres JL, Cascante M. Antiproliferative effect of antioxidant polyphenols from grape in murine Hepa-1c1c7. Eur J Nutr 2003, 42:43-49.
    • (2003) Eur J Nutr , vol.42 , pp. 43-49
    • Matito, C.1    Mastorakou, F.2    Centelles, J.J.3    Torres, J.L.4    Cascante, M.5
  • 40
    • 0029610477 scopus 로고
    • Review of the biology of Quercetin and related bioflavonoids
    • Formica JV, Regelson W. Review of the biology of Quercetin and related bioflavonoids. Food Chem Toxicol 1995, 33:1061-1080.
    • (1995) Food Chem Toxicol , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 44
    • 0025332564 scopus 로고
    • Nutritional control of rat liver fatty acid synthase and S14 mRNA abundance
    • Clarde WL, Armstrong MK, Jump DB. Nutritional control of rat liver fatty acid synthase and S14 mRNA abundance. J Nutr 1990, 120:218-224.
    • (1990) J Nutr , vol.120 , pp. 218-224
    • Clarde, W.L.1    Armstrong, M.K.2    Jump, D.B.3
  • 45
    • 0036105148 scopus 로고    scopus 로고
    • Block the FAS, lose the fat
    • Mobbs CV, Makimura H. Block the FAS, lose the fat. Nutr Med 2002, 8:335-336.
    • (2002) Nutr Med , vol.8 , pp. 335-336
    • Mobbs, C.V.1    Makimura, H.2
  • 46
    • 38049030825 scopus 로고    scopus 로고
    • Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3 T3-L1 cells
    • Moon HS, Chung CS, Lee HG, Kim TG, Choi YJ, Cho CS. Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3 T3-L1 cells. Obesity 2007, 15(11):2571-2582.
    • (2007) Obesity , vol.15 , Issue.11 , pp. 2571-2582
    • Moon, H.S.1    Chung, C.S.2    Lee, H.G.3    Kim, T.G.4    Choi, Y.J.5    Cho, C.S.6
  • 47
    • 0034806134 scopus 로고    scopus 로고
    • Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity
    • Thupari JN, Pinn ML, Kuhajda FP. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. Biochem Biophys Res Commun 2001, 285(2):217-223.
    • (2001) Biochem Biophys Res Commun , vol.285 , Issue.2 , pp. 217-223
    • Thupari, J.N.1    Pinn, M.L.2    Kuhajda, F.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.