Block the FAS, lose the fat

Nature Medicine

Volumn 8, Issue 4, 2002, Pages 335-336

  Mobbs, Charles V ^a   Makimura, Hideo ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; C 75; CERULENIN; ENZYME INHIBITOR; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; LEPTIN; UNCLASSIFIED DRUG;

DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HYPOTHALAMUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; SHORT SURVEY;

4-BUTYROLACTONE; ANIMALS; ANTI-OBESITY AGENTS; CERULENIN; ENZYME INHIBITORS; FATTY ACID SYNTHETASE COMPLEX; HUMANS; HYPOTHALAMUS; MICE; MICE, OBESE; MODELS, BIOLOGICAL; OBESITY;

EID: 0036105148     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0402-335     Document Type: Short Survey

References (10)

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3. Weight-reducing effects of the plasma protein encoded by the obese gene
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6. Intracellular signalling. Key enzyme in leptin-induced anorexia
7. Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
8. Hypothalamic glucose sensor: Similarities to and differences from pancreatic β-cell mechanisms
9. Central administration of oleic acid inhibits glucose production and food intake
10. Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides