HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Oncotarget

Volumn 4, Issue 11, 2013, Pages 1933-1947

  Brumatti, Gabriela ^a,b   Salmanidis, Marika ^a,b,d   Kok, Chung H ^d,e,f   Bilardi, Rebecca A ^a,b   Sandow, Jarrod J ^a,b   Silke, Natasha ^a,b   Mason, Kylie ^a,b   Visser, Jolanda ^a,g   Jabbour, Anissa M ^a,b   Glaser, Stefan P ^a,b   Okamoto, Toru ^h   Bouillet, Philippe ^a,b   D'Andrea, Richard J ^d,e,f   Ekert, Paul G ^a,b,c  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

^d CENTRE FOR CANCER BIOLOGY   (Australia)

^e QUEEN ELIZABETH HOSPITAL   (Australia)

^f UNIVERSITY OF ADELAIDE   (Australia)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h OSAKA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bcl 2; HoxA9; Leukemia

Indexed keywords

AFIMOXIFENE; GROWTH FACTOR; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN BCL 2; PROTEIN MEIS1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL SURVIVAL; DISEASE SEVERITY; GENE DELETION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MECHANICS; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ANIMALS; APOPTOSIS; CELL GROWTH PROCESSES; CELL SURVIVAL; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, BCL-2; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HOMEODOMAIN PROTEINS; INTERLEUKIN-3; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, TRANSGENIC; MYELOID CELLS; MYELOID PROGENITOR CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; TAMOXIFEN;

EID: 84890238768     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1306     Document Type: Article

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