Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

PLoS Pathogens

Volumn 9, Issue 12, 2013, Pages 1-16

  Elks, Philip M ^a,c   Brizee, Sabrina ^a   van der Vaart, Michiel ^a   Walmsley, Sarah R ^b   van Eeden, Fredericus J ^b   Renshaw, Stephen A ^b   Meijer, Annemarie H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; DIMETHYLOXALOYLGLYCINE; GLYCINE DERIVATIVE; GREEN FLUORESCENT PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; N (G) NITROARGININE METHYL ESTER; N6 (1 IMINOETHYL) LYSINE; OXYGENASE; PROLYL HYDROXYLASE 3; REACTIVE NITROGEN SPECIES; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; NITRIC OXIDE;

ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE PREDISPOSITION; EMBRYO; IN SITU HYBRIDIZATION; LARVA; LEUKOCYTE; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; NITROSYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ZEBRA FISH; ANIMAL; ATYPICAL MYCOBACTERIOSIS; CELL CULTURE; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM MARINUM; NITROSATION; PHYSIOLOGY; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYCOBACTERIUM INFECTIONS, NONTUBERCULOUS; MYCOBACTERIUM MARINUM; NEUTROPHILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITROSATION; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84890224385     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003789     Document Type: Article

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