-
1
-
-
68549109562
-
Osteosarcoma treatment: state of the art
-
10.1007/s10555-009-9186-7, 19214708
-
Ta HT, Dass CR, Choong PF, Dunstan DE. Osteosarcoma treatment: state of the art. Cancer Metastasis Rev 2009, 28:247-263. 10.1007/s10555-009-9186-7, 19214708.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 247-263
-
-
Ta, H.T.1
Dass, C.R.2
Choong, P.F.3
Dunstan, D.E.4
-
2
-
-
50649112829
-
Osteosarcoma development and stem cell differentiation
-
10.1007/s11999-008-0335-z, 2492997, 18563507
-
Tang N, Song WX, Luo J, Haydon RC, He TC. Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res 2008, 466:2114-2130. 10.1007/s11999-008-0335-z, 2492997, 18563507.
-
(2008)
Clin Orthop Relat Res
, vol.466
, pp. 2114-2130
-
-
Tang, N.1
Song, W.X.2
Luo, J.3
Haydon, R.C.4
He, T.C.5
-
3
-
-
50149110590
-
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
-
10.1073/pnas.0805462105, 2575280, 18697945
-
Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A 2008, 105:11851-11856. 10.1073/pnas.0805462105, 2575280, 18697945.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11851-11856
-
-
Berman, S.D.1
Calo, E.2
Landman, A.S.3
Danielian, P.S.4
Miller, E.S.5
West, J.C.6
Fonhoue, B.D.7
Caron, A.8
Bronson, R.9
Bouxsein, M.L.10
Mukherjee, S.11
Lees, J.A.12
-
4
-
-
45349086509
-
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
-
10.1101/gad.1656808, 2428063, 18559481
-
Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev 2008, 22:1662-1676. 10.1101/gad.1656808, 2428063, 18559481.
-
(2008)
Genes Dev
, vol.22
, pp. 1662-1676
-
-
Walkley, C.R.1
Qudsi, R.2
Sankaran, V.G.3
Perry, J.A.4
Gostissa, M.5
Roth, S.I.6
Rodda, S.J.7
Snay, E.8
Dunning, P.9
Fahey, F.H.10
Alt, F.W.11
McMahon, A.P.12
Orkin, S.H.13
-
5
-
-
84879686634
-
Genome-wide association study identifies two susceptibility loci for osteosarcoma
-
10.1038/ng.2645, 23727862
-
Savage SA, Mirabello L, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Flanagan AM, Tirabosco R, Andrulis IL, Wunder JS, Gokgoz N, Patino-Garcia A, Sierrasesumaga L, Lecanda F, Kurucu N, Ilhan IE, Sari N, Serra M, Hattinger C, Picci P, Spector LG, Barkauskas DA, Marina N, de Toledo SR, Petrilli AS, Amary MF, Halai D, Thomas DM, Douglass C, Meltzer PS, et al. Genome-wide association study identifies two susceptibility loci for osteosarcoma. Nat Genet 2013, 45:799-803. 10.1038/ng.2645, 23727862.
-
(2013)
Nat Genet
, vol.45
, pp. 799-803
-
-
Savage, S.A.1
Mirabello, L.2
Wang, Z.3
Gastier-Foster, J.M.4
Gorlick, R.5
Khanna, C.6
Flanagan, A.M.7
Tirabosco, R.8
Andrulis, I.L.9
Wunder, J.S.10
Gokgoz, N.11
Patino-Garcia, A.12
Sierrasesumaga, L.13
Lecanda, F.14
Kurucu, N.15
Ilhan, I.E.16
Sari, N.17
Serra, M.18
Hattinger, C.19
Picci, P.20
Spector, L.G.21
Barkauskas, D.A.22
Marina, N.23
de Toledo, S.R.24
Petrilli, A.S.25
Amary, M.F.26
Halai, D.27
Thomas, D.M.28
Douglass, C.29
Meltzer, P.S.30
more..
-
6
-
-
77449128013
-
Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression
-
10.1186/1471-2164-10-625, 2803201, 20028558
-
Paoloni M, Davis S, Lana S, Withrow S, Sangiorgi L, Picci P, Hewitt S, Triche T, Meltzer P, Khanna C. Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression. BMC Genomics 2009, 10:625. 10.1186/1471-2164-10-625, 2803201, 20028558.
-
(2009)
BMC Genomics
, vol.10
, pp. 625
-
-
Paoloni, M.1
Davis, S.2
Lana, S.3
Withrow, S.4
Sangiorgi, L.5
Picci, P.6
Hewitt, S.7
Triche, T.8
Meltzer, P.9
Khanna, C.10
-
7
-
-
79960597526
-
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach
-
10.1016/j.bone.2011.05.008, 3143255, 21621658
-
Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone 2011, 49:356-367. 10.1016/j.bone.2011.05.008, 3143255, 21621658.
-
(2011)
Bone
, vol.49
, pp. 356-367
-
-
Scott, M.C.1
Sarver, A.L.2
Gavin, K.J.3
Thayanithy, V.4
Getzy, D.M.5
Newman, R.A.6
Cutter, G.R.7
Lindblad-Toh, K.8
Kisseberth, W.C.9
Hunter, L.E.10
Subramanian, S.11
Breen, M.12
Modiano, J.F.13
-
9
-
-
33847693960
-
Comparative biology of human and canine osteosarcoma
-
Mueller F, Fuchs B, Kaser-Hotz B. Comparative biology of human and canine osteosarcoma. Anticancer Res 2007, 27:155-164.
-
(2007)
Anticancer Res
, vol.27
, pp. 155-164
-
-
Mueller, F.1
Fuchs, B.2
Kaser-Hotz, B.3
-
12
-
-
37349081282
-
Results of a web-based health survey of retired racing greyhounds
-
10.1111/j.1939-1676.2007.tb01945.x, 18196733
-
Lord LK, Yaissle JE, Marin L, Couto CG. Results of a web-based health survey of retired racing greyhounds. J Vet Intern Med 2007, 21:1243-1250. 10.1111/j.1939-1676.2007.tb01945.x, 18196733.
-
(2007)
J Vet Intern Med
, vol.21
, pp. 1243-1250
-
-
Lord, L.K.1
Yaissle, J.E.2
Marin, L.3
Couto, C.G.4
-
13
-
-
0032111945
-
Host related risk factors for canine osteosarcoma
-
10.1016/S1090-0233(98)80059-2, 9691849
-
Ru G, Terracini B, Glickman LT. Host related risk factors for canine osteosarcoma. Vet J 1998, 156:31-39. 10.1016/S1090-0233(98)80059-2, 9691849.
-
(1998)
Vet J
, vol.156
, pp. 31-39
-
-
Ru, G.1
Terracini, B.2
Glickman, L.T.3
-
14
-
-
28644447707
-
Genome sequence, comparative analysis and haplotype structure of the domestic dog
-
10.1038/nature04338, 16341006
-
Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, Ponting CP, Galibert F, Smith DR, DeJong PJ, Kirkness E, Alvarez P, Biagi T, Brockman W, Butler J, Chin CW, Cook A, Cuff J, Daly MJ, DeCaprio D, Gnerre S, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005, 438:803-819. 10.1038/nature04338, 16341006.
-
(2005)
Nature
, vol.438
, pp. 803-819
-
-
Lindblad-Toh, K.1
Wade, C.M.2
Mikkelsen, T.S.3
Karlsson, E.K.4
Jaffe, D.B.5
Kamal, M.6
Clamp, M.7
Chang, J.L.8
Kulbokas, E.J.9
Zody, M.C.10
Mauceli, E.11
Xie, X.12
Breen, M.13
Wayne, R.K.14
Ostrander, E.A.15
Ponting, C.P.16
Galibert, F.17
Smith, D.R.18
DeJong, P.J.19
Kirkness, E.20
Alvarez, P.21
Biagi, T.22
Brockman, W.23
Butler, J.24
Chin, C.W.25
Cook, A.26
Cuff, J.27
Daly, M.J.28
DeCaprio, D.29
Gnerre, S.30
more..
-
15
-
-
77649188325
-
Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex
-
10.1038/ng.525, 20101241
-
Wilbe M, Jokinen P, Truve K, Seppala EH, Karlsson EK, Biagi T, Hughes A, Bannasch D, Andersson G, Hansson-Hamlin H, Lohi H, Lindblad-Toh K. Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex. Nat Genet 2010, 42:250-254. 10.1038/ng.525, 20101241.
-
(2010)
Nat Genet
, vol.42
, pp. 250-254
-
-
Wilbe, M.1
Jokinen, P.2
Truve, K.3
Seppala, E.H.4
Karlsson, E.K.5
Biagi, T.6
Hughes, A.7
Bannasch, D.8
Andersson, G.9
Hansson-Hamlin, H.10
Lohi, H.11
Lindblad-Toh, K.12
-
16
-
-
78650856517
-
GCTA: a tool for genome-wide complex trait analysis
-
10.1016/j.ajhg.2010.11.011, 3014363, 21167468
-
Yang J, Lee SH, Goddard ME, Visscher PM. GCTA: a tool for genome-wide complex trait analysis. Am J Hum Genet 2011, 88:76-82. 10.1016/j.ajhg.2010.11.011, 3014363, 21167468.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 76-82
-
-
Yang, J.1
Lee, S.H.2
Goddard, M.E.3
Visscher, P.M.4
-
17
-
-
80055088614
-
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping
-
10.1371/journal.pgen.1002316, 3192833, 22022279
-
Vaysse A, Ratnakumar A, Derrien T, Axelsson E, Rosengren Pielberg G, Sigurdsson S, Fall T, Seppala EH, Hansen MS, Lawley CT, Karlsson EK, LUPA C, Bannasch D, Vila C, Lohi H, Galibert F, Fredholm M, Haggstrom J, Hedhammar A, Andre C, Lindblad-Toh K, Hitte C, Webster MT. Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet 2011, 7:e1002316. 10.1371/journal.pgen.1002316, 3192833, 22022279.
-
(2011)
PLoS Genet
, vol.7
-
-
Vaysse, A.1
Ratnakumar, A.2
Derrien, T.3
Axelsson, E.4
Rosengren Pielberg, G.5
Sigurdsson, S.6
Fall, T.7
Seppala, E.H.8
Hansen, M.S.9
Lawley, C.T.10
Karlsson, E.K.11
Lupa, C.12
Bannasch, D.13
Vila, C.14
Lohi, H.15
Galibert, F.16
Fredholm, M.17
Haggstrom, J.18
Hedhammar, A.19
Andre, C.20
Lindblad-Toh, K.21
Hitte, C.22
Webster, M.T.23
more..
-
18
-
-
77953811255
-
New approaches to population stratification in genome-wide association studies
-
2975875, 20548291
-
Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nat Rev Genet 2010, 11:459-463. 2975875, 20548291.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 459-463
-
-
Price, A.L.1
Zaitlen, N.A.2
Reich, D.3
Patterson, N.4
-
19
-
-
77950301214
-
Variance component model to account for sample structure in genome-wide association studies
-
10.1038/ng.548, 3092069, 20208533
-
Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nat Genet 2010, 42:348-354. 10.1038/ng.548, 3092069, 20208533.
-
(2010)
Nat Genet
, vol.42
, pp. 348-354
-
-
Kang, H.M.1
Sul, J.H.2
Service, S.K.3
Zaitlen, N.A.4
Kong, S.Y.5
Freimer, N.B.6
Sabatti, C.7
Eskin, E.8
-
20
-
-
35648953308
-
Efficient mapping of mendelian traits in dogs through genome-wide association
-
10.1038/ng.2007.10, 17906626
-
Karlsson EK, Baranowska I, Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N, Biagi TM, Patterson N, Pielberg GR, Kulbokas EJ, Comstock KE, Keller ET, Mesirov JP, von Euler H, Kampe O, Hedhammar A, Lander ES, Andersson G, Andersson L, Lindblad-Toh K. Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet 2007, 39:1321-1328. 10.1038/ng.2007.10, 17906626.
-
(2007)
Nat Genet
, vol.39
, pp. 1321-1328
-
-
Karlsson, E.K.1
Baranowska, I.2
Wade, C.M.3
Salmon Hillbertz, N.H.4
Zody, M.C.5
Anderson, N.6
Biagi, T.M.7
Patterson, N.8
Pielberg, G.R.9
Kulbokas, E.J.10
Comstock, K.E.11
Keller, E.T.12
Mesirov, J.P.13
von Euler, H.14
Kampe, O.15
Hedhammar, A.16
Lander, E.S.17
Andersson, G.18
Andersson, L.19
Lindblad-Toh, K.20
more..
-
21
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
10.1038/nature11247, 3439153, 22955616, Encode Project Consortium
-
Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M, Encode Project Consortium An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74. 10.1038/nature11247, 3439153, 22955616, Encode Project Consortium.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
22
-
-
78651237647
-
Identifying a high fraction of the human genome to be under selective constraint using GERP++
-
10.1371/journal.pcbi.1001025, 2996323, 21152010
-
Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S. Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput Biol 2010, 6:e1001025. 10.1371/journal.pcbi.1001025, 2996323, 21152010.
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Davydov, E.V.1
Goode, D.L.2
Sirota, M.3
Cooper, G.M.4
Sidow, A.5
Batzoglou, S.6
-
23
-
-
84875404794
-
The UCSC genome browser database: extensions and updates 2013
-
10.1093/nar/gks1048, 3531082, 23155063
-
Meyer LR, Zweig AS, Hinrichs AS, Karolchik D, Kuhn RM, Wong M, Sloan CA, Rosenbloom KR, Roe G, Rhead B, Raney BJ, Pohl A, Malladi VS, Li CH, Lee BT, Learned K, Kirkup V, Hsu F, Heitner S, Harte RA, Haeussler M, Guruvadoo L, Goldman M, Giardine BM, Fujita PA, Dreszer TR, Diekhans M, Cline MS, Clawson H, Barber GP, et al. The UCSC genome browser database: extensions and updates 2013. Nucleic Acids Res 2013, 41:D64-D69. 10.1093/nar/gks1048, 3531082, 23155063.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Meyer, L.R.1
Zweig, A.S.2
Hinrichs, A.S.3
Karolchik, D.4
Kuhn, R.M.5
Wong, M.6
Sloan, C.A.7
Rosenbloom, K.R.8
Roe, G.9
Rhead, B.10
Raney, B.J.11
Pohl, A.12
Malladi, V.S.13
Li, C.H.14
Lee, B.T.15
Learned, K.16
Kirkup, V.17
Hsu, F.18
Heitner, S.19
Harte, R.A.20
Haeussler, M.21
Guruvadoo, L.22
Goldman, M.23
Giardine, B.M.24
Fujita, P.A.25
Dreszer, T.R.26
Diekhans, M.27
Cline, M.S.28
Clawson, H.29
Barber, G.P.30
more..
-
24
-
-
84861859517
-
ENCODE whole-genome data in the UCSC genome browser: update 2012
-
10.1093/nar/gkr1012, 3245183, 22075998
-
Rosenbloom KR, Dreszer TR, Long JC, Malladi VS, Sloan CA, Raney BJ, Cline MS, Karolchik D, Barber GP, Clawson H, Diekhans M, Fujita PA, Goldman M, Gravell RC, Harte RA, Hinrichs AS, Kirkup VM, Kuhn RM, Learned K, Maddren M, Meyer LR, Pohl A, Rhead B, Wong MC, Zweig AS, Haussler D, Kent WJ. ENCODE whole-genome data in the UCSC genome browser: update 2012. Nucleic Acids Res 2012, 40:D912-D917. 10.1093/nar/gkr1012, 3245183, 22075998.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Rosenbloom, K.R.1
Dreszer, T.R.2
Long, J.C.3
Malladi, V.S.4
Sloan, C.A.5
Raney, B.J.6
Cline, M.S.7
Karolchik, D.8
Barber, G.P.9
Clawson, H.10
Diekhans, M.11
Fujita, P.A.12
Goldman, M.13
Gravell, R.C.14
Harte, R.A.15
Hinrichs, A.S.16
Kirkup, V.M.17
Kuhn, R.M.18
Learned, K.19
Maddren, M.20
Meyer, L.R.21
Pohl, A.22
Rhead, B.23
Wong, M.C.24
Zweig, A.S.25
Haussler, D.26
Kent, W.J.27
more..
-
25
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
10.1073/pnas.1016071107, 3003124, 21106759
-
Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A 2010, 107:21931-21936. 10.1073/pnas.1016071107, 3003124, 21106759.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
Carey, B.W.5
Steine, E.J.6
Hanna, J.7
Lodato, M.A.8
Frampton, G.M.9
Sharp, P.A.10
Boyer, L.A.11
Young, R.A.12
Jaenisch, R.13
-
26
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
10.1038/nature11232, 3721348, 22955617
-
Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, Canfield TK, Diegel M, Dunn D, Ebersol AK, Frum T, Giste E, Johnson AK, Johnson EM, Kutyavin T, Lajoie B, Lee K, London D, Lotakis D, Neph S, et al. The accessible chromatin landscape of the human genome. Nature 2012, 489:75-82. 10.1038/nature11232, 3721348, 22955617.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
Garg, K.11
John, S.12
Sandstrom, R.13
Bates, D.14
Boatman, L.15
Canfield, T.K.16
Diegel, M.17
Dunn, D.18
Ebersol, A.K.19
Frum, T.20
Giste, E.21
Johnson, A.K.22
Johnson, E.M.23
Kutyavin, T.24
Lajoie, B.25
Lee, K.26
London, D.27
Lotakis, D.28
Neph, S.29
more..
-
27
-
-
84862281808
-
The genetics of osteosarcoma
-
3364016, 22685381
-
Martin JW, Squire JA, Zielenska M. The genetics of osteosarcoma. Sarcoma 2012, 2012:627254. 3364016, 22685381.
-
(2012)
Sarcoma
, vol.2012
, pp. 627254
-
-
Martin, J.W.1
Squire, J.A.2
Zielenska, M.3
-
28
-
-
0035915773
-
Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas
-
10.1002/1097-0215(20010120)95:1<34::AID-IJC1006>3.0.CO;2-V, 11241308
-
Maitra A, Roberts H, Weinberg AG, Geradts J. Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas. Int J Cancer 2001, 95:34-38. 10.1002/1097-0215(20010120)95:1<34::AID-IJC1006>3.0.CO;2-V, 11241308.
-
(2001)
Int J Cancer
, vol.95
, pp. 34-38
-
-
Maitra, A.1
Roberts, H.2
Weinberg, A.G.3
Geradts, J.4
-
29
-
-
84867855432
-
P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy
-
10.1016/j.humpath.2012.02.003, 22578565
-
Borys D, Canter RJ, Hoch B, Martinez SR, Tamurian RM, Murphy B, Bishop JW, Horvai A. P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy. Hum Pathol 2012, 43:1948-1954. 10.1016/j.humpath.2012.02.003, 22578565.
-
(2012)
Hum Pathol
, vol.43
, pp. 1948-1954
-
-
Borys, D.1
Canter, R.J.2
Hoch, B.3
Martinez, S.R.4
Tamurian, R.M.5
Murphy, B.6
Bishop, J.W.7
Horvai, A.8
-
30
-
-
84875301605
-
The genomic signature of dog domestication reveals adaptation to a starch-rich diet
-
10.1038/nature11837, 23354050
-
Axelsson E, Ratnakumar A, Arendt ML, Maqbool K, Webster MT, Perloski M, Liberg O, Arnemo JM, Hedhammar A, Lindblad-Toh K. The genomic signature of dog domestication reveals adaptation to a starch-rich diet. Nature 2013, 495:360-364. 10.1038/nature11837, 23354050.
-
(2013)
Nature
, vol.495
, pp. 360-364
-
-
Axelsson, E.1
Ratnakumar, A.2
Arendt, M.L.3
Maqbool, K.4
Webster, M.T.5
Perloski, M.6
Liberg, O.7
Arnemo, J.M.8
Hedhammar, A.9
Lindblad-Toh, K.10
-
31
-
-
79953300078
-
FIMO: scanning for occurrences of a given motif
-
10.1093/bioinformatics/btr064, 3065696, 21330290
-
Grant CE, Bailey TL, Noble WS. FIMO: scanning for occurrences of a given motif. Bioinformatics 2011, 27:1017-1018. 10.1093/bioinformatics/btr064, 3065696, 21330290.
-
(2011)
Bioinformatics
, vol.27
, pp. 1017-1018
-
-
Grant, C.E.1
Bailey, T.L.2
Noble, W.S.3
-
32
-
-
34447506667
-
Quantifying similarity between motifs
-
10.1186/gb-2007-8-2-r24, 1852410, 17324271
-
Gupta S, Stamatoyannopoulos JA, Bailey TL, Noble WS. Quantifying similarity between motifs. Genome Biol 2007, 8:R24. 10.1186/gb-2007-8-2-r24, 1852410, 17324271.
-
(2007)
Genome Biol
, vol.8
-
-
Gupta, S.1
Stamatoyannopoulos, J.A.2
Bailey, T.L.3
Noble, W.S.4
-
33
-
-
77955851132
-
How B cells influence bone biology in health and disease
-
10.1016/j.bone.2010.06.011, 2941392, 20601290
-
Horowitz MC, Fretz JA, Lorenzo JA. How B cells influence bone biology in health and disease. Bone 2010, 47:472-479. 10.1016/j.bone.2010.06.011, 2941392, 20601290.
-
(2010)
Bone
, vol.47
, pp. 472-479
-
-
Horowitz, M.C.1
Fretz, J.A.2
Lorenzo, J.A.3
-
34
-
-
84869477285
-
The transcription factor paired box-5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin
-
10.1002/jbmr.1708, 22807088
-
Hinoi E, Nakatani E, Yamamoto T, Iezaki T, Takahata Y, Fujita H, Ishiura R, Takamori M, Yoneda Y. The transcription factor paired box-5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin. J Bone Miner Res 2012, 27:2526-2534. 10.1002/jbmr.1708, 22807088.
-
(2012)
J Bone Miner Res
, vol.27
, pp. 2526-2534
-
-
Hinoi, E.1
Nakatani, E.2
Yamamoto, T.3
Iezaki, T.4
Takahata, Y.5
Fujita, H.6
Ishiura, R.7
Takamori, M.8
Yoneda, Y.9
-
35
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
10.1086/519795, 1950838, 17701901
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007, 81:559-575. 10.1086/519795, 1950838, 17701901.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.I.9
Daly, M.J.10
Sham, P.C.11
-
36
-
-
79951473520
-
9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response
-
10.1038/nature09753, 3079517, 21307941
-
Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response. Nature 2011, 470:264-268. 10.1038/nature09753, 3079517, 21307941.
-
(2011)
Nature
, vol.470
, pp. 264-268
-
-
Harismendy, O.1
Notani, D.2
Song, X.3
Rahim, N.G.4
Tanasa, B.5
Heintzman, N.6
Ren, B.7
Fu, X.D.8
Topol, E.J.9
Rosenfeld, M.G.10
Frazer, K.A.11
-
37
-
-
67651205715
-
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions
-
10.1371/journal.pgen.1000534, 2694358, 19557189
-
Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet 2009, 5:e1000534. 10.1371/journal.pgen.1000534, 2694358, 19557189.
-
(2009)
PLoS Genet
, vol.5
-
-
Raychaudhuri, S.1
Plenge, R.M.2
Rossin, E.J.3
Ng, A.C.4
Purcell, S.M.5
Sklar, P.6
Scolnick, E.M.7
Xavier, R.J.8
Altshuler, D.9
Daly, M.J.10
-
38
-
-
84861640022
-
OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells
-
10.1002/ijc.26474, 21964830
-
Bunt J, Hasselt NE, Zwijnenburg DA, Hamdi M, Koster J, Versteeg R, Kool M. OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells. Int J Cancer 2012, 131:E21-E32. 10.1002/ijc.26474, 21964830.
-
(2012)
Int J Cancer
, vol.131
-
-
Bunt, J.1
Hasselt, N.E.2
Zwijnenburg, D.A.3
Hamdi, M.4
Koster, J.5
Versteeg, R.6
Kool, M.7
-
39
-
-
34447536862
-
Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells
-
10.1074/jbc.M701570200, 17400546
-
Koike N, Kassai Y, Kouta Y, Miwa H, Konishi M, Itoh N. Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells. J Biol Chem 2007, 282:15843-15850. 10.1074/jbc.M701570200, 17400546.
-
(2007)
J Biol Chem
, vol.282
, pp. 15843-15850
-
-
Koike, N.1
Kassai, Y.2
Kouta, Y.3
Miwa, H.4
Konishi, M.5
Itoh, N.6
-
40
-
-
31644437052
-
The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling
-
10.1242/dev.02171, 16319118
-
Deckelbaum RA, Majithia A, Booker T, Henderson JE, Loomis CA. The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling. Development 2006, 133:63-74. 10.1242/dev.02171, 16319118.
-
(2006)
Development
, vol.133
, pp. 63-74
-
-
Deckelbaum, R.A.1
Majithia, A.2
Booker, T.3
Henderson, J.E.4
Loomis, C.A.5
-
41
-
-
0034028904
-
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis
-
10.1038/74307, 10742114
-
Bulman MP, Kusumi K, Frayling TM, McKeown C, Garrett C, Lander ES, Krumlauf R, Hattersley AT, Ellard S, Turnpenny PD. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nat Genet 2000, 24:438-441. 10.1038/74307, 10742114.
-
(2000)
Nat Genet
, vol.24
, pp. 438-441
-
-
Bulman, M.P.1
Kusumi, K.2
Frayling, T.M.3
McKeown, C.4
Garrett, C.5
Lander, E.S.6
Krumlauf, R.7
Hattersley, A.T.8
Ellard, S.9
Turnpenny, P.D.10
-
42
-
-
28544433632
-
Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development
-
10.1084/jem.20051325, 2213340, 16314436
-
Matsubara A, Iwama A, Yamazaki S, Furuta C, Hirasawa R, Morita Y, Osawa M, Motohashi T, Eto K, Ema H, Kitamura T, Vestweber D, Nakauchi H. Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development. J Exp Med 2005, 202:1483-1492. 10.1084/jem.20051325, 2213340, 16314436.
-
(2005)
J Exp Med
, vol.202
, pp. 1483-1492
-
-
Matsubara, A.1
Iwama, A.2
Yamazaki, S.3
Furuta, C.4
Hirasawa, R.5
Morita, Y.6
Osawa, M.7
Motohashi, T.8
Eto, K.9
Ema, H.10
Kitamura, T.11
Vestweber, D.12
Nakauchi, H.13
-
43
-
-
84862795172
-
FAM5C is a soluble osteoblast differentiation factor linking muscle to bone
-
10.1016/j.bbrc.2011.12.147, 22245424
-
Tanaka K, Matsumoto E, Higashimaki Y, Sugimoto T, Seino S, Kaji H. FAM5C is a soluble osteoblast differentiation factor linking muscle to bone. Biochem Biophys Res Commun 2012, 418:134-139. 10.1016/j.bbrc.2011.12.147, 22245424.
-
(2012)
Biochem Biophys Res Commun
, vol.418
, pp. 134-139
-
-
Tanaka, K.1
Matsumoto, E.2
Higashimaki, Y.3
Sugimoto, T.4
Seino, S.5
Kaji, H.6
-
44
-
-
79960897850
-
NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation
-
10.1016/j.febslet.2011.06.024, 3209538, 21723284
-
Zou X, Shen J, Chen F, Ting K, Zheng Z, Pang S, Zara JN, Adams JS, Soo C, Zhang X. NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation. FEBS Lett 2011, 585:2410-2418. 10.1016/j.febslet.2011.06.024, 3209538, 21723284.
-
(2011)
FEBS Lett
, vol.585
, pp. 2410-2418
-
-
Zou, X.1
Shen, J.2
Chen, F.3
Ting, K.4
Zheng, Z.5
Pang, S.6
Zara, J.N.7
Adams, J.S.8
Soo, C.9
Zhang, X.10
-
45
-
-
0032545355
-
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis
-
10.1006/bbrc.1998.9788, 9878548
-
Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Yano K, Morinaga T, Higashio K. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res Commun 1998, 253:395-400. 10.1006/bbrc.1998.9788, 9878548.
-
(1998)
Biochem Biophys Res Commun
, vol.253
, pp. 395-400
-
-
Nakagawa, N.1
Kinosaki, M.2
Yamaguchi, K.3
Shima, N.4
Yasuda, H.5
Yano, K.6
Morinaga, T.7
Higashio, K.8
-
46
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
10.1073/pnas.0307323101, 365734, 14973191
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M, Croce CM. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004, 101:2999-3004. 10.1073/pnas.0307323101, 365734, 14973191.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
Croce, C.M.11
-
47
-
-
58149186477
-
PID: the pathway interaction database
-
10.1093/nar/gkn653, 2686461, 18832364
-
Schaefer CF, Anthony K, Krupa S, Buchoff J, Day M, Hannay T, Buetow KH. PID: the pathway interaction database. Nucleic Acids Res 2009, 37:D674-D679. 10.1093/nar/gkn653, 2686461, 18832364.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Schaefer, C.F.1
Anthony, K.2
Krupa, S.3
Buchoff, J.4
Day, M.5
Hannay, T.6
Buetow, K.H.7
-
48
-
-
15244358503
-
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
-
10.1038/nature03441, 2923337, 15735639
-
Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 2005, 434:338-345. 10.1038/nature03441, 2923337, 15735639.
-
(2005)
Nature
, vol.434
, pp. 338-345
-
-
Xie, X.1
Lu, J.2
Kulbokas, E.J.3
Golub, T.R.4
Mootha, V.5
Lindblad-Toh, K.6
Lander, E.S.7
Kellis, M.8
-
49
-
-
4744349390
-
Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation
-
10.1074/jbc.M403702200, 15292260
-
Schroeder TM, Kahler RA, Li X, Westendorf JJ. Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation. J Biol Chem 2004, 279:41998-42007. 10.1074/jbc.M403702200, 15292260.
-
(2004)
J Biol Chem
, vol.279
, pp. 41998-42007
-
-
Schroeder, T.M.1
Kahler, R.A.2
Li, X.3
Westendorf, J.J.4
-
50
-
-
84863987483
-
INRICH: interval-based enrichment analysis for genome-wide association studies
-
10.1093/bioinformatics/bts191, 3381960, 22513993
-
Lee PH, O'Dushlaine C, Thomas B, Purcell SM. INRICH: interval-based enrichment analysis for genome-wide association studies. Bioinformatics 2012, 28:1797-1799. 10.1093/bioinformatics/bts191, 3381960, 22513993.
-
(2012)
Bioinformatics
, vol.28
, pp. 1797-1799
-
-
Lee, P.H.1
O'Dushlaine, C.2
Thomas, B.3
Purcell, S.M.4
-
51
-
-
84859386766
-
MiRNA signatures associate with pathogenesis and progression of osteosarcoma
-
10.1158/0008-5472.CAN-11-2663, 3328547, 22350417
-
Jones KB, Salah Z, Del Mare S, Galasso M, Gaudio E, Nuovo GJ, Lovat F, LeBlanc K, Palatini J, Randall RL, Volinia S, Stein GS, Croce CM, Lian JB, Ageilan RI. miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res 2012, 72:1865-1877. 10.1158/0008-5472.CAN-11-2663, 3328547, 22350417.
-
(2012)
Cancer Res
, vol.72
, pp. 1865-1877
-
-
Jones, K.B.1
Salah, Z.2
Del Mare, S.3
Galasso, M.4
Gaudio, E.5
Nuovo, G.J.6
Lovat, F.7
LeBlanc, K.8
Palatini, J.9
Randall, R.L.10
Volinia, S.11
Stein, G.S.12
Croce, C.M.13
Lian, J.B.14
Ageilan, R.I.15
-
52
-
-
80052664464
-
Identification of differentially expressed microRNAs in Osteosarcoma
-
3140035, 21789031
-
Lulla RR, Costa FF, Bischof JM, Chou PM, de Bonaldo FM, Vanin EF, Soares MB. Identification of differentially expressed microRNAs in Osteosarcoma. Sarcoma 2011, 2011:732690. 3140035, 21789031.
-
(2011)
Sarcoma
, vol.2011
, pp. 732690
-
-
Lulla, R.R.1
Costa, F.F.2
Bischof, J.M.3
Chou, P.M.4
de Bonaldo, F.M.5
Vanin, E.F.6
Soares, M.B.7
-
53
-
-
79960673180
-
Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma
-
10.1016/j.cancergen.2010.12.012, 21504713
-
Maire G, Martin JW, Yoshimoto M, Chilton-MacNeill S, Zielenska M, Squire JA. Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma. Cancer Genet 2011, 204:138-146. 10.1016/j.cancergen.2010.12.012, 21504713.
-
(2011)
Cancer Genet
, vol.204
, pp. 138-146
-
-
Maire, G.1
Martin, J.W.2
Yoshimoto, M.3
Chilton-MacNeill, S.4
Zielenska, M.5
Squire, J.A.6
-
54
-
-
77951791258
-
S-MED: sarcoma microRNA expression database
-
10.1038/labinvest.2010.53, 20212452
-
Sarver AL, Phalak R, Thayanithy V, Subramanian S. S-MED: sarcoma microRNA expression database. Lab Invest 2010, 90:753-761. 10.1038/labinvest.2010.53, 20212452.
-
(2010)
Lab Invest
, vol.90
, pp. 753-761
-
-
Sarver, A.L.1
Phalak, R.2
Thayanithy, V.3
Subramanian, S.4
-
55
-
-
80755184684
-
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma
-
10.1016/j.bone.2011.10.012, 3755949, 22037351
-
Thayanithy V, Sarver AL, Kartha RV, Li L, Angstadt AY, Breen M, Steer CJ, Modiano JF, Subramanian S. Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone 2012, 50:171-181. 10.1016/j.bone.2011.10.012, 3755949, 22037351.
-
(2012)
Bone
, vol.50
, pp. 171-181
-
-
Thayanithy, V.1
Sarver, A.L.2
Kartha, R.V.3
Li, L.4
Angstadt, A.Y.5
Breen, M.6
Steer, C.J.7
Modiano, J.F.8
Subramanian, S.9
-
56
-
-
84869398364
-
A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations
-
10.1016/j.cancergen.2012.09.005, 23137772
-
Angstadt AY, Thayanithy V, Subramanian S, Modiano JF, Breen M. A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations. Cancer Genet 2012, 205:572-587. 10.1016/j.cancergen.2012.09.005, 23137772.
-
(2012)
Cancer Genet
, vol.205
, pp. 572-587
-
-
Angstadt, A.Y.1
Thayanithy, V.2
Subramanian, S.3
Modiano, J.F.4
Breen, M.5
-
57
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
-
10.1073/pnas.0710052104, 2148413, 18077431
-
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A 2007, 104:20007-20012. 10.1073/pnas.0710052104, 2148413, 18077431.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
Linhart, D.6
Vivanco, I.7
Lee, J.C.8
Huang, J.H.9
Alexander, S.10
Du, J.11
Kau, T.12
Thomas, R.K.13
Shah, K.14
Soto, H.15
Perner, S.16
Prensner, J.17
Debiasi, R.M.18
Demichelis, F.19
Hatton, C.20
Rubin, M.A.21
Garraway, L.A.22
Nelson, S.F.23
Liau, L.24
Mischel, P.S.25
Cloughesy, T.F.26
Meyerson, M.27
Golub, T.A.28
Lander, E.S.29
Mellinghoff, I.K.30
more..
-
58
-
-
80053984156
-
Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method
-
10.1016/j.canlet.2011.07.028, 21943823
-
Okamura Y, Nomoto S, Hayashi M, Hishida M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Takeda S, Kodera Y, Nakao A. Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method. Cancer Lett 2011, 312:150-157. 10.1016/j.canlet.2011.07.028, 21943823.
-
(2011)
Cancer Lett
, vol.312
, pp. 150-157
-
-
Okamura, Y.1
Nomoto, S.2
Hayashi, M.3
Hishida, M.4
Nishikawa, Y.5
Yamada, S.6
Fujii, T.7
Sugimoto, H.8
Takeda, S.9
Kodera, Y.10
Nakao, A.11
-
59
-
-
84860662550
-
Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
-
10.1002/gcc.21956, 22454324
-
Kuijjer ML, Rydbeck H, Kresse SH, Buddingh EP, Lid AB, Roelofs H, Burger H, Myklebost O, Hogendoorn PC, Meza-Zepeda LA, Cleton-Jansen AM. Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data. Genes Chromosomes Cancer 2012, 51:696-706. 10.1002/gcc.21956, 22454324.
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 696-706
-
-
Kuijjer, M.L.1
Rydbeck, H.2
Kresse, S.H.3
Buddingh, E.P.4
Lid, A.B.5
Roelofs, H.6
Burger, H.7
Myklebost, O.8
Hogendoorn, P.C.9
Meza-Zepeda, L.A.10
Cleton-Jansen, A.M.11
-
60
-
-
77953436610
-
MicroRNAs regulate osteogenesis and chondrogenesis of mouse bone marrow stromal cells
-
2733092, 19787082
-
Suomi S, Taipaleenmaki H, Seppanen A, Ripatti T, Vaananen K, Hentunen T, Saamanen AM, Laitala-Leinonen T. MicroRNAs regulate osteogenesis and chondrogenesis of mouse bone marrow stromal cells. Gene Regul Syst Bio 2008, 2:177-191. 2733092, 19787082.
-
(2008)
Gene Regul Syst Bio
, vol.2
, pp. 177-191
-
-
Suomi, S.1
Taipaleenmaki, H.2
Seppanen, A.3
Ripatti, T.4
Vaananen, K.5
Hentunen, T.6
Saamanen, A.M.7
Laitala-Leinonen, T.8
-
61
-
-
66249148694
-
Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
-
10.1158/0008-5472.CAN-08-4025, 19435910
-
Agirre X, Vilas-Zornoza A, Jimenez-Velasco A, Martin-Subero JI, Cordeu L, Garate L, San Jose-Eneriz E, Abizanda G, Rodriguez-Otero P, Fortes P, Rifon J, Bandres E, Calasanz MJ, Martin V, Heiniger A, Torres A, Siebert R, Roman-Gomez J, Prosper F. Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia. Cancer Res 2009, 69:4443-4453. 10.1158/0008-5472.CAN-08-4025, 19435910.
-
(2009)
Cancer Res
, vol.69
, pp. 4443-4453
-
-
Agirre, X.1
Vilas-Zornoza, A.2
Jimenez-Velasco, A.3
Martin-Subero, J.I.4
Cordeu, L.5
Garate, L.6
San Jose-Eneriz, E.7
Abizanda, G.8
Rodriguez-Otero, P.9
Fortes, P.10
Rifon, J.11
Bandres, E.12
Calasanz, M.J.13
Martin, V.14
Heiniger, A.15
Torres, A.16
Siebert, R.17
Roman-Gomez, J.18
Prosper, F.19
-
62
-
-
67650561896
-
IkappaBzeta expression is regulated by miR-124a
-
10.4161/cc.8.13.8816, 19502795
-
Lindenblatt C, Schulze-Osthoff K, Totzke G. IkappaBzeta expression is regulated by miR-124a. Cell Cycle 2009, 8:2019-2023. 10.4161/cc.8.13.8816, 19502795.
-
(2009)
Cell Cycle
, vol.8
, pp. 2019-2023
-
-
Lindenblatt, C.1
Schulze-Osthoff, K.2
Totzke, G.3
-
63
-
-
84863582976
-
The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer
-
10.1158/1055-9965.EPI-12-0190-T, 3392365, 22623710
-
Shearin AL, Hedan B, Cadieu E, Erich SA, Schmidt EV, Faden DL, Cullen J, Abadie J, Kwon EM, Grone A, Devauchelle P, Rimbault M, Karyadi DM, Lynch M, Galibert F, Breen M, Rutteman GR, Andre C, Parker HG, Ostrander EA. The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer. Cancer Epidemiol Biomarkers Prev 2012, 21:1019-1027. 10.1158/1055-9965.EPI-12-0190-T, 3392365, 22623710.
-
(2012)
Cancer Epidemiol Biomarkers Prev
, vol.21
, pp. 1019-1027
-
-
Shearin, A.L.1
Hedan, B.2
Cadieu, E.3
Erich, S.A.4
Schmidt, E.V.5
Faden, D.L.6
Cullen, J.7
Abadie, J.8
Kwon, E.M.9
Grone, A.10
Devauchelle, P.11
Rimbault, M.12
Karyadi, D.M.13
Lynch, M.14
Galibert, F.15
Breen, M.16
Rutteman, G.R.17
Andre, C.18
Parker, H.G.19
Ostrander, E.A.20
more..
-
64
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
10.1073/pnas.0903103106, 2687147, 19474294
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 2009, 106:9362-9367. 10.1073/pnas.0903103106, 2687147, 19474294.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
65
-
-
0029032415
-
Overexpression of p53 and MDM2 proteins in cervical neoplasia
-
Lukas Z, Vojtesek B, Anton M, Picksley SM, Kubalek V. Overexpression of p53 and MDM2 proteins in cervical neoplasia. Folia Biol (Praha) 1995, 41:197-199.
-
(1995)
Folia Biol (Praha)
, vol.41
, pp. 197-199
-
-
Lukas, Z.1
Vojtesek, B.2
Anton, M.3
Picksley, S.M.4
Kubalek, V.5
-
66
-
-
6044254972
-
P19ARF directly and differentially controls the functions of c-Myc independently of p53
-
10.1038/nature02958, 15361884
-
Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR. p19ARF directly and differentially controls the functions of c-Myc independently of p53. Nature 2004, 431:712-717. 10.1038/nature02958, 15361884.
-
(2004)
Nature
, vol.431
, pp. 712-717
-
-
Qi, Y.1
Gregory, M.A.2
Li, Z.3
Brousal, J.P.4
West, K.5
Hann, S.R.6
-
67
-
-
0842265035
-
The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis
-
10.1038/sj.onc.1207074, 14724566
-
Sharpless NE, Ramsey MR, Balasubramanian P, Castrillon DH, DePinho RA. The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis. Oncogene 2004, 23:379-385. 10.1038/sj.onc.1207074, 14724566.
-
(2004)
Oncogene
, vol.23
, pp. 379-385
-
-
Sharpless, N.E.1
Ramsey, M.R.2
Balasubramanian, P.3
Castrillon, D.H.4
DePinho, R.A.5
-
68
-
-
84868340057
-
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest
-
10.1016/j.stem.2012.08.001, 23122289
-
Hidalgo I, Herrera-Merchan A, Ligos JM, Carramolino L, Nunez J, Martinez F, Dominguez O, Torres M, Gonzalez S. Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest. Cell Stem Cell 2012, 11:649-662. 10.1016/j.stem.2012.08.001, 23122289.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 649-662
-
-
Hidalgo, I.1
Herrera-Merchan, A.2
Ligos, J.M.3
Carramolino, L.4
Nunez, J.5
Martinez, F.6
Dominguez, O.7
Torres, M.8
Gonzalez, S.9
-
69
-
-
77956222562
-
Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer
-
10.1016/j.stem.2010.08.002, 20804967
-
Sauvageau M, Sauvageau G. Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell 2010, 7:299-313. 10.1016/j.stem.2010.08.002, 20804967.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 299-313
-
-
Sauvageau, M.1
Sauvageau, G.2
-
70
-
-
84873607054
-
Glutamate signaling in healthy and diseased bone
-
3400067, 22833735
-
Cowan RW, Seidlitz EP, Singh G. Glutamate signaling in healthy and diseased bone. Front Endocrinol (Lausanne) 2012, 3:89. 3400067, 22833735.
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 89
-
-
Cowan, R.W.1
Seidlitz, E.P.2
Singh, G.3
-
71
-
-
0037452854
-
Glutamate receptor function in learning and memory
-
10.1016/S0166-4328(02)00272-3, 12644276
-
Riedel G, Platt B, Micheau J. Glutamate receptor function in learning and memory. Behav Brain Res 2003, 140:1-47. 10.1016/S0166-4328(02)00272-3, 12644276.
-
(2003)
Behav Brain Res
, vol.140
, pp. 1-47
-
-
Riedel, G.1
Platt, B.2
Micheau, J.3
-
72
-
-
84870783570
-
Attention-deficit/hyperactivity disorder genomics: update for clinicians
-
10.1007/s11920-012-0309-4, 22843546
-
Elia J, Sackett J, Turner T, Schardt M, Tang SC, Kurtz N, Dunfey M, McFarlane NA, Susi A, Danish D, Li A, Nissley-Tsiopinis J, Borgmann-Winter K. Attention-deficit/hyperactivity disorder genomics: update for clinicians. Curr Psychiatry Rep 2012, 14:579-589. 10.1007/s11920-012-0309-4, 22843546.
-
(2012)
Curr Psychiatry Rep
, vol.14
, pp. 579-589
-
-
Elia, J.1
Sackett, J.2
Turner, T.3
Schardt, M.4
Tang, S.C.5
Kurtz, N.6
Dunfey, M.7
McFarlane, N.A.8
Susi, A.9
Danish, D.10
Li, A.11
Nissley-Tsiopinis, J.12
Borgmann-Winter, K.13
-
73
-
-
84869753622
-
Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder
-
10.1038/tp.2012.95, 3565768, 23149448
-
Lee PH, Perlis RH, Jung JY, Byrne EM, Rueckert E, Siburian R, Haddad S, Mayerfeld CE, Heath AC, Pergadia ML, Madden PA, Boomsma DI, Penninx BW, Sklar P, Martin NG, Wray NR, Purcell SM, Smoller JW. Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Transl Psychiatry 2012, 2:e184. 10.1038/tp.2012.95, 3565768, 23149448.
-
(2012)
Transl Psychiatry
, vol.2
-
-
Lee, P.H.1
Perlis, R.H.2
Jung, J.Y.3
Byrne, E.M.4
Rueckert, E.5
Siburian, R.6
Haddad, S.7
Mayerfeld, C.E.8
Heath, A.C.9
Pergadia, M.L.10
Madden, P.A.11
Boomsma, D.I.12
Penninx, B.W.13
Sklar, P.14
Martin, N.G.15
Wray, N.R.16
Purcell, S.M.17
Smoller, J.W.18
-
74
-
-
84879422520
-
Genome-wide association study of obsessive-compulsive disorder
-
10.1038/mp.2012.85, 22889921
-
Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Davis LK, Osiecki L, McGrath L, Haddad S, Crane J, Hezel D, Illman C, Mayerfield C, Konkashbaev A, Liu C, Pluzhnikov A, Tikhomirov A, Edlund CK, Rauch SL, Moessner R, Falkai P, Maier W, Ruhrmann S, Grabe HJ, Lennertz L, Wagner M, et al. Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry 2013, 18:788-798. 10.1038/mp.2012.85, 22889921.
-
(2013)
Mol Psychiatry
, vol.18
, pp. 788-798
-
-
Stewart, S.E.1
Yu, D.2
Scharf, J.M.3
Neale, B.M.4
Fagerness, J.A.5
Mathews, C.A.6
Arnold, P.D.7
Evans, P.D.8
Gamazon, E.R.9
Davis, L.K.10
Osiecki, L.11
McGrath, L.12
Haddad, S.13
Crane, J.14
Hezel, D.15
Illman, C.16
Mayerfield, C.17
Konkashbaev, A.18
Liu, C.19
Pluzhnikov, A.20
Tikhomirov, A.21
Edlund, C.K.22
Rauch, S.L.23
Moessner, R.24
Falkai, P.25
Maier, W.26
Ruhrmann, S.27
Grabe, H.J.28
Lennertz, L.29
Wagner, M.30
more..
-
75
-
-
72949099043
-
A canine chromosome 7 locus confers compulsive disorder susceptibility
-
10.1038/mp.2009.111, 20029408
-
Dodman NH, Karlsson EK, Moon-Fanelli A, Galdzicka M, Perloski M, Shuster L, Lindblad-Toh K, Ginns EI. A canine chromosome 7 locus confers compulsive disorder susceptibility. Mol Psychiatry 2010, 15:8-10. 10.1038/mp.2009.111, 20029408.
-
(2010)
Mol Psychiatry
, vol.15
, pp. 8-10
-
-
Dodman, N.H.1
Karlsson, E.K.2
Moon-Fanelli, A.3
Galdzicka, M.4
Perloski, M.5
Shuster, L.6
Lindblad-Toh, K.7
Ginns, E.I.8
-
76
-
-
78650856517
-
GCTA: a tool for genome-wide complex trait analysis
-
Yang J, Lee S, Goddard M, Visscher P. GCTA: a tool for genome-wide complex trait analysis. Am J Human Gen 2010, 88:76-82.
-
(2010)
Am J Human Gen
, vol.88
, pp. 76-82
-
-
Yang, J.1
Lee, S.2
Goddard, M.3
Visscher, P.4
-
77
-
-
77950301214
-
Variance component model to account for sample structure in genome-wide association studies
-
10.1038/ng.548, 3092069, 20208533
-
Kang H, Sul J, Service S, Zaitlen N, Kong S-Y, Freimer N, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nat Genet 2010, 42:348-354. 10.1038/ng.548, 3092069, 20208533.
-
(2010)
Nat Genet
, vol.42
, pp. 348-354
-
-
Kang, H.1
Sul, J.2
Service, S.3
Zaitlen, N.4
Kong, S.-Y.5
Freimer, N.6
Sabatti, C.7
Eskin, E.8
-
78
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
10.1038/nature05911, 2719288, 17554300
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678. 10.1038/nature05911, 2719288, 17554300.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
79
-
-
77949587649
-
Fast and accurate long-read alignment with Burrows-Wheeler transform
-
10.1093/bioinformatics/btp698, 2828108, 20080505
-
Li H, Durbin R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 2010, 26:589-595. 10.1093/bioinformatics/btp698, 2828108, 20080505.
-
(2010)
Bioinformatics
, vol.26
, pp. 589-595
-
-
Li, H.1
Durbin, R.2
-
80
-
-
84890227390
-
-
Picard http://picard.sourceforge.net.
-
Picard
-
-
-
81
-
-
77956295988
-
The genome analysis toolkit: a mapreduce framework for analyzing next-generation DNA sequencing data
-
10.1101/gr.107524.110, 2928508, 20644199
-
McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, Garimella K, Altshuler D, Gabriel S, Daly M, DePristo MA. The genome analysis toolkit: a mapreduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010, 20:1297-1303. 10.1101/gr.107524.110, 2928508, 20644199.
-
(2010)
Genome Res
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
Hanna, M.2
Banks, E.3
Sivachenko, A.4
Cibulskis, K.5
Kernytsky, A.6
Garimella, K.7
Altshuler, D.8
Gabriel, S.9
Daly, M.10
DePristo, M.A.11
-
82
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
10.1038/ng.806, 3083463, 21478889
-
DePristo MA, Banks E, Poplin R, Garimella KV, Maguire JR, Hartl C, Philippakis AA, del Angel G, Rivas MA, Hanna M, McKenna A, Fennell TJ, Kernytsky AM, Sivachenko AY, Cibulskis K, Gabriel SB, Altshuler D, Daly MJ. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet 2011, 43:491-498. 10.1038/ng.806, 3083463, 21478889.
-
(2011)
Nat Genet
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
Banks, E.2
Poplin, R.3
Garimella, K.V.4
Maguire, J.R.5
Hartl, C.6
Philippakis, A.A.7
del Angel, G.8
Rivas, M.A.9
Hanna, M.10
McKenna, A.11
Fennell, T.J.12
Kernytsky, A.M.13
Sivachenko, A.Y.14
Cibulskis, K.15
Gabriel, S.B.16
Altshuler, D.17
Daly, M.J.18
-
83
-
-
72049111749
-
Host genetics influences on HIV type-1 disease
-
10.3851/IMP1253, 2851194, 19812435
-
Fellay J. Host genetics influences on HIV type-1 disease. Antivir Ther 2009, 14:731-738. 10.3851/IMP1253, 2851194, 19812435.
-
(2009)
Antivir Ther
, vol.14
, pp. 731-738
-
-
Fellay, J.1
-
84
-
-
84878497738
-
SEQscoring: a tool to facilitate the interpretation of data generated with next generation sequencing technologies
-
Truve K, Eriksson O, Norling N, Wilbe M, Mauceli E, Lindblad-Toh K, Bongcam-Rudloff E. SEQscoring: a tool to facilitate the interpretation of data generated with next generation sequencing technologies. EMBnet journal 2011, 17:38-45.
-
(2011)
EMBnet journal
, vol.17
, pp. 38-45
-
-
Truve, K.1
Eriksson, O.2
Norling, N.3
Wilbe, M.4
Mauceli, E.5
Lindblad-Toh, K.6
Bongcam-Rudloff, E.7
-
85
-
-
84862506964
-
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3
-
10.4161/fly.19695, 3679285, 22728672
-
Cingolani P, Platts A, Wang Le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly (Austin) 2012, 6:80-92. 10.4161/fly.19695, 3679285, 22728672.
-
(2012)
Fly (Austin)
, vol.6
, pp. 80-92
-
-
Cingolani, P.1
Platts, A.2
Wang Le, L.3
Coon, M.4
Nguyen, T.5
Wang, L.6
Land, S.J.7
Lu, X.8
Ruden, D.M.9
-
86
-
-
84867119898
-
Integrative genomics viewer (IGV): high-performance genomics data visualization and exploration
-
Thorvaldsdottir H, Robinson JT, Mesirov JP. Integrative genomics viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform 2012, 2012:2012.
-
(2012)
Brief Bioinform
, vol.2012
, pp. 2012
-
-
Thorvaldsdottir, H.1
Robinson, J.T.2
Mesirov, J.P.3
-
87
-
-
80054973803
-
A high-resolution map of human evolutionary constraint using 29 mammals
-
10.1038/nature10530, 3207357, 21993624
-
Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G, Mauceli E, Ward LD, Lowe CB, Holloway AK, Clamp M, Gnerre S, Alfoldi J, Beal K, Chang J, Clawson H, Cuff J, Di Palma F, Fitzgerald S, Flicek P, Guttman M, Hubisz MJ, Jaffe DB, Jungreis I, Kent WJ, Kostka D, Lara M, et al. A high-resolution map of human evolutionary constraint using 29 mammals. Nature 2011, 478:476-482. 10.1038/nature10530, 3207357, 21993624.
-
(2011)
Nature
, vol.478
, pp. 476-482
-
-
Lindblad-Toh, K.1
Garber, M.2
Zuk, O.3
Lin, M.F.4
Parker, B.J.5
Washietl, S.6
Kheradpour, P.7
Ernst, J.8
Jordan, G.9
Mauceli, E.10
Ward, L.D.11
Lowe, C.B.12
Holloway, A.K.13
Clamp, M.14
Gnerre, S.15
Alfoldi, J.16
Beal, K.17
Chang, J.18
Clawson, H.19
Cuff, J.20
Di Palma, F.21
Fitzgerald, S.22
Flicek, P.23
Guttman, M.24
Hubisz, M.J.25
Jaffe, D.B.26
Jungreis, I.27
Kent, W.J.28
Kostka, D.29
Lara, M.30
more..
-
88
-
-
62649155943
-
A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals
-
10.1016/j.ajhg.2009.01.005, 2668004, 19200528
-
Browning BL, Browning SR. A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet 2009, 84:210-223. 10.1016/j.ajhg.2009.01.005, 2668004, 19200528.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 210-223
-
-
Browning, B.L.1
Browning, S.R.2
-
89
-
-
84890245234
-
-
http://www.atcc.org/Standards/Standards_Programs/ATCC_Standards_Development_Organization.aspx.
-
-
-
-
91
-
-
84890191884
-
-
Ensembl http://www.ensembl.org/biomart.
-
Ensembl
-
-
-
93
-
-
84859436530
-
NCBI reference sequences (RefSeq): current status, new features and genome annotation policy
-
10.1093/nar/gkr1079, 3245008, 22121212
-
Pruitt KD, Tatusova T, Brown GR, Maglott DR. NCBI reference sequences (RefSeq): current status, new features and genome annotation policy. Nucleic Acids Res 2012, 40:D130-D135. 10.1093/nar/gkr1079, 3245008, 22121212.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Pruitt, K.D.1
Tatusova, T.2
Brown, G.R.3
Maglott, D.R.4
-
94
-
-
79959592516
-
Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas
-
10.3109/10428194.2011.559802, 21375435
-
Thomas R, Seiser EL, Motsinger-Reif A, Borst L, Valli VE, Kelley K, Suter SE, Argyle D, Burgess K, Bell J, Lindblad-Toh K, Modiano JF, Breen M. Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas. Leuk Lymphoma 2011, 52:1321-1335. 10.3109/10428194.2011.559802, 21375435.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1321-1335
-
-
Thomas, R.1
Seiser, E.L.2
Motsinger-Reif, A.3
Borst, L.4
Valli, V.E.5
Kelley, K.6
Suter, S.E.7
Argyle, D.8
Burgess, K.9
Bell, J.10
Lindblad-Toh, K.11
Modiano, J.F.12
Breen, M.13
-
95
-
-
84890154473
-
-
http://www.broadinstitute.org/ftp/pub/vgb/dog/OSA_GenomeBiology2013paper.
-
-
-
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