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Volumn 47, Issue 3, 2010, Pages 472-479

How B cells influence bone biology in health and disease

Author keywords

B cell activation; B cell differentiation; B cell transcription factors and bone; IL 7; Macrophage osteoclast differentiation; Regulation of B cell development by RANKL RANK signaling; Regulation of hematopoiesis by osteoblast lineage cells

Indexed keywords

ESTROGEN; HELIX LOOP HELIX PROTEIN; IKAROS TRANSCRIPTION FACTOR; INTERLEUKIN 7; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROTEIN EBF1; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG;

EID: 77955851132     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.06.011     Document Type: Review
Times cited : (86)

References (80)
  • 2
    • 1942457308 scopus 로고    scopus 로고
    • Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
    • Visnjic D., Kalajzic Z., Rowe D.W., Katavic V., Lorenzo J., Aquila H.L. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood 2004, 103:3258-3264.
    • (2004) Blood , vol.103 , pp. 3258-3264
    • Visnjic, D.1    Kalajzic, Z.2    Rowe, D.W.3    Katavic, V.4    Lorenzo, J.5    Aquila, H.L.6
  • 3
    • 34247332650 scopus 로고    scopus 로고
    • Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells
    • Zhu J., Garrett R., Jung Y., Zhang Y., Kim N., Wang J., et al. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood 2007, 109:3706-3712.
    • (2007) Blood , vol.109 , pp. 3706-3712
    • Zhu, J.1    Garrett, R.2    Jung, Y.3    Zhang, Y.4    Kim, N.5    Wang, J.6
  • 4
    • 0038406789 scopus 로고    scopus 로고
    • Biology of hematopoietic stem cells and progenitors: implications for clinical application
    • Kondo M., Wagers A.J., Manz M.G., Prohaska S.S., Sherer D.C., Beilhack G.F., et al. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol 2003, 21:759-806.
    • (2003) Annu Rev Immunol , vol.21 , pp. 759-806
    • Kondo, M.1    Wagers, A.J.2    Manz, M.G.3    Prohaska, S.S.4    Sherer, D.C.5    Beilhack, G.F.6
  • 6
  • 7
    • 0034969086 scopus 로고    scopus 로고
    • Factors and forces controlling V(D)J recombination
    • Hesslein D.G., Schatz D.G. Factors and forces controlling V(D)J recombination. Adv Immunol 2001, 78:169-232.
    • (2001) Adv Immunol , vol.78 , pp. 169-232
    • Hesslein, D.G.1    Schatz, D.G.2
  • 8
  • 9
    • 0030483542 scopus 로고    scopus 로고
    • Identification of the earliest B lineage stage in mouse bone marrow
    • Li Y.S., Wasserman R., Hayakawa K., Hardy R.R. Identification of the earliest B lineage stage in mouse bone marrow. Immunity 1996, 5:527-535.
    • (1996) Immunity , vol.5 , pp. 527-535
    • Li, Y.S.1    Wasserman, R.2    Hayakawa, K.3    Hardy, R.R.4
  • 11
    • 0033991261 scopus 로고    scopus 로고
    • Receptor editing in B cells
    • Nemazee D. Receptor editing in B cells. Adv Immunol 2000, 74:89-126.
    • (2000) Adv Immunol , vol.74 , pp. 89-126
    • Nemazee, D.1
  • 12
    • 0027992622 scopus 로고
    • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
    • Bain G., Maandag E.C., Izon D.J., Amsen D., Kruisbeek A.M., Weintraub B.D., et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 1994, 79:885-892.
    • (1994) Cell , vol.79 , pp. 885-892
    • Bain, G.1    Maandag, E.C.2    Izon, D.J.3    Amsen, D.4    Kruisbeek, A.M.5    Weintraub, B.D.6
  • 13
    • 0029045161 scopus 로고
    • Failure of B-cell differentiation in mice lacking the transcription factor EBF
    • Lin H., Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 1995, 376:263-267.
    • (1995) Nature , vol.376 , pp. 263-267
    • Lin, H.1    Grosschedl, R.2
  • 14
    • 0026698147 scopus 로고
    • Pax5 encodes the transcription factor BSAP and is expressed in B-lymphocytes, the developing CNS, and adult testis
    • Adams B., Dorfler P., Aguzzi A., Kozmik Z., Urbanek P., Maurer-Fogy I., et al. Pax5 encodes the transcription factor BSAP and is expressed in B-lymphocytes, the developing CNS, and adult testis. Genes Dev 1992, 6:1589-1607.
    • (1992) Genes Dev , vol.6 , pp. 1589-1607
    • Adams, B.1    Dorfler, P.2    Aguzzi, A.3    Kozmik, Z.4    Urbanek, P.5    Maurer-Fogy, I.6
  • 15
    • 0033533891 scopus 로고    scopus 로고
    • Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
    • Nutt S.L., Heavey B., Rolink A.G., Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999, 401:556-562.
    • (1999) Nature , vol.401 , pp. 556-562
    • Nutt, S.L.1    Heavey, B.2    Rolink, A.G.3    Busslinger, M.4
  • 18
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: intelligent design
    • Mazzucchelli R.M., Durum S.K. Interleukin-7 receptor expression: intelligent design. Nat Rev Immunol 2007, 7:144-154.
    • (2007) Nat Rev Immunol , vol.7 , pp. 144-154
    • Mazzucchelli, R.M.1    Durum, S.K.2
  • 19
    • 0030875168 scopus 로고    scopus 로고
    • Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency
    • Miyaura C., Onoe Y., Inada M., Maki K., Ikuta K., Ito M., et al. Increased B-lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: similarity to estrogen deficiency. Proc Natl Acad Sci U S A 1997, 94:9360-9365.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9360-9365
    • Miyaura, C.1    Onoe, Y.2    Inada, M.3    Maki, K.4    Ikuta, K.5    Ito, M.6
  • 20
    • 0036897349 scopus 로고    scopus 로고
    • Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency
    • Weitzmann M.N., Roggia C., Toraldo G., Weitzmann L., Pacifici R. Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest 2002, 110:1643-1650.
    • (2002) J Clin Invest , vol.110 , pp. 1643-1650
    • Weitzmann, M.N.1    Roggia, C.2    Toraldo, G.3    Weitzmann, L.4    Pacifici, R.5
  • 21
    • 0034284296 scopus 로고    scopus 로고
    • Interleukin-7 stimulates osteoclast formation by up-regulating the T- cell production of soluble osteoclastogenic cytokines
    • Weitzmann M.N., Cenci S., Rifas L., Brown C., Pacifici R. Interleukin-7 stimulates osteoclast formation by up-regulating the T- cell production of soluble osteoclastogenic cytokines. Blood 2000, 96:1873-1878.
    • (2000) Blood , vol.96 , pp. 1873-1878
    • Weitzmann, M.N.1    Cenci, S.2    Rifas, L.3    Brown, C.4    Pacifici, R.5
  • 22
    • 57449106476 scopus 로고    scopus 로고
    • Increased bone resorption and osteopenia are a part of the lymphoproliferative phenotype of mice with systemic over-expression of interleukin-7 gene driven by MHC class II promoter
    • Salopek D., Grcevic D., Katavic V., Kovacic N., Lukic I.K., Marusic A. Increased bone resorption and osteopenia are a part of the lymphoproliferative phenotype of mice with systemic over-expression of interleukin-7 gene driven by MHC class II promoter. Immunol Lett 2008, 121:134-139.
    • (2008) Immunol Lett , vol.121 , pp. 134-139
    • Salopek, D.1    Grcevic, D.2    Katavic, V.3    Kovacic, N.4    Lukic, I.K.5    Marusic, A.6
  • 23
    • 0037422560 scopus 로고    scopus 로고
    • IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells
    • Toraldo G., Roggia C., Qian W.P., Pacifici R., Weitzmann M.N. IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells. Proc Natl Acad Sci U S A 2003, 100:125-130.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 125-130
    • Toraldo, G.1    Roggia, C.2    Qian, W.P.3    Pacifici, R.4    Weitzmann, M.N.5
  • 24
    • 53549135488 scopus 로고    scopus 로고
    • Alpha1beta1 integrin and interleukin-7 receptor up-regulate the expression of RANKL in human T cells and enhance their osteoclastogenic function
    • Gendron S., Boisvert M., Chetoui N., Aoudjit F. Alpha1beta1 integrin and interleukin-7 receptor up-regulate the expression of RANKL in human T cells and enhance their osteoclastogenic function. Immunology 2008, 125:359-369.
    • (2008) Immunology , vol.125 , pp. 359-369
    • Gendron, S.1    Boisvert, M.2    Chetoui, N.3    Aoudjit, F.4
  • 26
    • 33646248066 scopus 로고    scopus 로고
    • Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss
    • Lee S.K., Kalinowski J.F., Jacquin C., Adams D.J., Gronowicz G., Lorenzo J.A. Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss. J Bone Miner Res 2006, 21:695-702.
    • (2006) J Bone Miner Res , vol.21 , pp. 695-702
    • Lee, S.K.1    Kalinowski, J.F.2    Jacquin, C.3    Adams, D.J.4    Gronowicz, G.5    Lorenzo, J.A.6
  • 27
    • 28044466907 scopus 로고    scopus 로고
    • An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency
    • Ryan M.R., Shepherd R., Leavey J.K., Gao Y., Grassi F., Schnell F.J., et al. An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency. Proc Natl Acad Sci U S A 2005, 102:16735-16740.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 16735-16740
    • Ryan, M.R.1    Shepherd, R.2    Leavey, J.K.3    Gao, Y.4    Grassi, F.5    Schnell, F.J.6
  • 28
    • 33845752070 scopus 로고    scopus 로고
    • Production of IL-7 is increased in ovariectomized mice, but not RANKL mRNA expression by osteoblasts/stromal cells in bone, and IL-7 enhances generation of osteoclast precursors in vitro
    • Sato T., Watanabe K., Masuhara M., Hada N., Hakeda Y. Production of IL-7 is increased in ovariectomized mice, but not RANKL mRNA expression by osteoblasts/stromal cells in bone, and IL-7 enhances generation of osteoclast precursors in vitro. J Bone Miner Metab 2007, 25:19-27.
    • (2007) J Bone Miner Metab , vol.25 , pp. 19-27
    • Sato, T.1    Watanabe, K.2    Masuhara, M.3    Hada, N.4    Hakeda, Y.5
  • 29
    • 28544432254 scopus 로고    scopus 로고
    • Osteoblast specific overexpression of human interleukin-7 increases femoral trabecular bone mass in female mice and inhibits in vitro osteoclastogenesis
    • Lee S., Kalinowski J.F., Adams D.J., Aguila H.L., Lorenzo J.A. Osteoblast specific overexpression of human interleukin-7 increases femoral trabecular bone mass in female mice and inhibits in vitro osteoclastogenesis. J Bone Miner Res 2004, 19:S410.
    • (2004) J Bone Miner Res , vol.19
    • Lee, S.1    Kalinowski, J.F.2    Adams, D.J.3    Aguila, H.L.4    Lorenzo, J.A.5
  • 30
    • 33748056871 scopus 로고    scopus 로고
    • Osteoblast specific overexpression of human interlukin-7 rescues the bone phenotype of interleukin-7 deficient female mice
    • Lee S., Kalinowski J.F., Adams D.J., Aguila H.L., Lorenzo J.A. Osteoblast specific overexpression of human interlukin-7 rescues the bone phenotype of interleukin-7 deficient female mice. J Bone Miner Res 2005, 20:S48.
    • (2005) J Bone Miner Res , vol.20
    • Lee, S.1    Kalinowski, J.F.2    Adams, D.J.3    Aguila, H.L.4    Lorenzo, J.A.5
  • 31
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
    • Scott E.W., Simon M.C., Anastasi J., Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994, 265:1573-1577.
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 33
    • 0030611964 scopus 로고    scopus 로고
    • PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
    • Scott E.W., Fisher R.C., Olson M.C., Kehrli E.W., Simon M.C., Singh H. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 1997, 6:427-447.
    • (1997) Immunity , vol.6 , pp. 427-447
    • Scott, E.W.1    Fisher, R.C.2    Olson, M.C.3    Kehrli, E.W.4    Simon, M.C.5    Singh, H.6
  • 34
    • 0032479989 scopus 로고    scopus 로고
    • Pu.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors
    • DeKoter R.P., Walsh J.C., H.Singh Pu.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. EMBO J 1998, 17:4456-4468.
    • (1998) EMBO J , vol.17 , pp. 4456-4468
    • DeKoter, R.P.1    Walsh, J.C.2
  • 35
    • 0034717335 scopus 로고    scopus 로고
    • Regulation of B lymphocyte and macrophage development by graded expression of PU.1
    • DeKoter R.P., Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 2000, 288:1439-1441.
    • (2000) Science , vol.288 , pp. 1439-1441
    • DeKoter, R.P.1    Singh, H.2
  • 36
    • 0036199657 scopus 로고    scopus 로고
    • Pu.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
    • DeKoter R.P., Lee H.-J., H.Singh Pu.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 2002, 16:297-309.
    • (2002) Immunity , vol.16 , pp. 297-309
    • DeKoter, R.P.1    Lee, H.-J.2
  • 37
    • 0025246676 scopus 로고
    • The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
    • Klemsz M.J., McKercher S.R., Celada A., Van Beveren C., Maki R.A. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell 1990, 61:113-124.
    • (1990) Cell , vol.61 , pp. 113-124
    • Klemsz, M.J.1    McKercher, S.R.2    Celada, A.3    Van Beveren, C.4    Maki, R.A.5
  • 38
    • 0027972426 scopus 로고
    • Comparison of the expression and function of the transcription factor PU.1 (Spi-1 proto-oncogene) between murine macrophages and B lymphocytes
    • Ross I.L., Dunn T.l., Yue X., Roy S., Barnett C.J., Hume Da. Comparison of the expression and function of the transcription factor PU.1 (Spi-1 proto-oncogene) between murine macrophages and B lymphocytes. Oncogene 1994, 9:121-132.
    • (1994) Oncogene , vol.9 , pp. 121-132
    • Ross, I.L.1    Dunn, T.2    Yue, X.3    Roy, S.4    Barnett, C.J.5    Hume, D.6
  • 39
    • 0036519296 scopus 로고    scopus 로고
    • Haematopoietic cell-fate decisions, chromatin regulation and Ikaros
    • Georgopoulos K. Haematopoietic cell-fate decisions, chromatin regulation and Ikaros. Nat Rev Immunol 2002, 2:162-174.
    • (2002) Nat Rev Immunol , vol.2 , pp. 162-174
    • Georgopoulos, K.1
  • 40
    • 14544287884 scopus 로고    scopus 로고
    • Ikaros-family proteins: in search of molecular functions during lymphocytes development
    • Cobb B.S., Smale S.T. Ikaros-family proteins: in search of molecular functions during lymphocytes development. Curr Top Microbiol Immunol 2005, 290:29-47.
    • (2005) Curr Top Microbiol Immunol , vol.290 , pp. 29-47
    • Cobb, B.S.1    Smale, S.T.2
  • 41
    • 0032560018 scopus 로고    scopus 로고
    • Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
    • Kelley C.M., Ikeda T., Koipally J., Avitahl N., Wu L., Georgopoulos K., et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr Biol 1998, 8:508-515.
    • (1998) Curr Biol , vol.8 , pp. 508-515
    • Kelley, C.M.1    Ikeda, T.2    Koipally, J.3    Avitahl, N.4    Wu, L.5    Georgopoulos, K.6
  • 42
    • 0028001362 scopus 로고
    • The Ikaros gene is required for the development of all lymphoid lineages
    • Georgopoulos K., Bigby M., Wang J.H., Molnar A., Wu P., Winandy S., et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994, 79:143-156.
    • (1994) Cell , vol.79 , pp. 143-156
    • Georgopoulos, K.1    Bigby, M.2    Wang, J.H.3    Molnar, A.4    Wu, P.5    Winandy, S.6
  • 43
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang J.H., Nichogiannopoulou A., Wu L., Sun L., Sharpe A.H., Bigby M., et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996, 5:537-549.
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1    Nichogiannopoulou, A.2    Wu, L.3    Sun, L.4    Sharpe, A.H.5    Bigby, M.6
  • 44
    • 0030933151 scopus 로고    scopus 로고
    • The role of the Ikaros gene in lymphocyte development and homeostasis
    • Georgopoulos K., Winady S., Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annu Rev Immunol 1997, 15:155-176.
    • (1997) Annu Rev Immunol , vol.15 , pp. 155-176
    • Georgopoulos, K.1    Winady, S.2    Avitahl, N.3
  • 45
    • 47849118209 scopus 로고    scopus 로고
    • Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros
    • Reynaud D., Demarco I.A., Reddy K.L., Schjerven H., Bertolino E., Chen Z., et al. Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol 2008, 9:927-936.
    • (2008) Nat Immunol , vol.9 , pp. 927-936
    • Reynaud, D.1    Demarco, I.A.2    Reddy, K.L.3    Schjerven, H.4    Bertolino, E.5    Chen, Z.6
  • 46
    • 0024554495 scopus 로고
    • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    • Murre C., McCaw P.S., Baltimore D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 1989, 56:777-783.
    • (1989) Cell , vol.56 , pp. 777-783
    • Murre, C.1    McCaw, P.S.2    Baltimore, D.3
  • 47
    • 60549106831 scopus 로고    scopus 로고
    • E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors
    • Semerad C.L., Mercer E.M., Inlay M.A., Weissman I.L., Murre C. E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc Natl Acad Sci U S A 2009, 106:1930-1935.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1930-1935
    • Semerad, C.L.1    Mercer, E.M.2    Inlay, M.A.3    Weissman, I.L.4    Murre, C.5
  • 48
    • 1142285361 scopus 로고    scopus 로고
    • Regulation of E2A gene expression in B-lymphocyte development
    • Zhuang Y., Jackson A., Pan L., Shen K., Dai M. Regulation of E2A gene expression in B-lymphocyte development. Mol Immunol 2004, 40:1165-1177.
    • (2004) Mol Immunol , vol.40 , pp. 1165-1177
    • Zhuang, Y.1    Jackson, A.2    Pan, L.3    Shen, K.4    Dai, M.5
  • 49
    • 38449102306 scopus 로고    scopus 로고
    • Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
    • Pongubala J.M., Northrup D.L., Lancki D.W., Medina K.L., Treiber T., Bertolino E., et al. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol 2008, 9:203-215.
    • (2008) Nat Immunol , vol.9 , pp. 203-215
    • Pongubala, J.M.1    Northrup, D.L.2    Lancki, D.W.3    Medina, K.L.4    Treiber, T.5    Bertolino, E.6
  • 50
    • 61849181511 scopus 로고    scopus 로고
    • Ebf1 dependent control of the osteoblast and adipocyte lineages
    • Hesslein D.G.T., Fretz J.A., Xi Y., Nelson T., Zhou S., Lorenzo J.A., et al. Ebf1 dependent control of the osteoblast and adipocyte lineages. Bone 2009, 44:537-546.
    • (2009) Bone , vol.44 , pp. 537-546
    • Hesslein, D.G.T.1    Fretz, J.A.2    Xi, Y.3    Nelson, T.4    Zhou, S.5    Lorenzo, J.A.6
  • 51
    • 0036839672 scopus 로고    scopus 로고
    • Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation
    • Akerblad P., Lind U., Liberg D., Bamberg K., Sigvardsson M. Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation. Mol Cell Biol 2002, 22:8015-8025.
    • (2002) Mol Cell Biol , vol.22 , pp. 8015-8025
    • Akerblad, P.1    Lind, U.2    Liberg, D.3    Bamberg, K.4    Sigvardsson, M.5
  • 52
    • 0027997502 scopus 로고
    • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
    • Urbanek P., Wang Z., Fetka I., Wagner E., Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 1994, 79:901-912.
    • (1994) Cell , vol.79 , pp. 901-912
    • Urbanek, P.1    Wang, Z.2    Fetka, I.3    Wagner, E.4    Busslinger, M.5
  • 53
    • 9144260054 scopus 로고    scopus 로고
    • Pax5 deficient mice exhibit early onset osteoporosis with increased osteoclast progenitors
    • Horowitz M.C., Xi Y., Pflugh D.L., Hesslein D.G.T., Schatz D.G., Lorenzo J.A., et al. Pax5 deficient mice exhibit early onset osteoporosis with increased osteoclast progenitors. J Immunol 2004, 173:6583-6591.
    • (2004) J Immunol , vol.173 , pp. 6583-6591
    • Horowitz, M.C.1    Xi, Y.2    Pflugh, D.L.3    Hesslein, D.G.T.4    Schatz, D.G.5    Lorenzo, J.A.6
  • 54
    • 0033533891 scopus 로고    scopus 로고
    • Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
    • Nutt S.L., Heavey B., Rolink A.G., Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999, 401:556-562.
    • (1999) Nature , vol.401 , pp. 556-562
    • Nutt, S.L.1    Heavey, B.2    Rolink, A.G.3    Busslinger, M.4
  • 55
    • 0035230221 scopus 로고    scopus 로고
    • Bipotential B-macrophage progenitors are present in adult bone marrow
    • Montecino-Rodriguez E., Leathers H., Dorshkind K. Bipotential B-macrophage progenitors are present in adult bone marrow. Nat Immunol 2001, 2:83-88.
    • (2001) Nat Immunol , vol.2 , pp. 83-88
    • Montecino-Rodriguez, E.1    Leathers, H.2    Dorshkind, K.3
  • 57
    • 34247323904 scopus 로고    scopus 로고
    • B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo
    • Li Y., Toraldo G., Li A., Yang X., Zhang H., Qian W.-P., et al. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood 2007, 109:3839-3848.
    • (2007) Blood , vol.109 , pp. 3839-3848
    • Li, Y.1    Toraldo, G.2    Li, A.3    Yang, X.4    Zhang, H.5    Qian, W.-P.6
  • 58
    • 0032079445 scopus 로고    scopus 로고
    • Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
    • Bucay N., Sarosi I., Dunstan C.R., Morony S., Tarpley J., Capparelli C., et al. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 1998, 12:1260-1268.
    • (1998) Genes Dev , vol.12 , pp. 1260-1268
    • Bucay, N.1    Sarosi, I.2    Dunstan, C.R.3    Morony, S.4    Tarpley, J.5    Capparelli, C.6
  • 59
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong Y.-Y., Yoshida H., Sarosi I., Tan H.-L., Timms E., Capparelli C., et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999, 397:315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.-Y.1    Yoshida, H.2    Sarosi, I.3    Tan, H.-L.4    Timms, E.5    Capparelli, C.6
  • 61
    • 0033561039 scopus 로고    scopus 로고
    • TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
    • Lomaga M.A., Yeh W.-C., Sarosi I., Duncan G.S., Furlonger C., Ho A., et al. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev 1999, 15:1015-1024.
    • (1999) Genes Dev , vol.15 , pp. 1015-1024
    • Lomaga, M.A.1    Yeh, W.-C.2    Sarosi, I.3    Duncan, G.S.4    Furlonger, C.5    Ho, A.6
  • 62
    • 0035253693 scopus 로고    scopus 로고
    • Osteoprotegerin, a crucial regulator of bone metabolism, also regulates B cell development and function
    • Yun T.J., Tallquist M.D., Aicher A., Rafferty K.L., Marshall A.J., Moon J.J., et al. Osteoprotegerin, a crucial regulator of bone metabolism, also regulates B cell development and function. J Immunol 2001, 166:1482-1491.
    • (2001) J Immunol , vol.166 , pp. 1482-1491
    • Yun, T.J.1    Tallquist, M.D.2    Aicher, A.3    Rafferty, K.L.4    Marshall, A.J.5    Moon, J.J.6
  • 63
    • 16544378699 scopus 로고    scopus 로고
    • Characterization of a novel bipotent hematopoietic progenitor population in normal and osteopetrotic mice
    • Blin-Wakkach C., Wakkach A., Rochet N., Carle G.F. Characterization of a novel bipotent hematopoietic progenitor population in normal and osteopetrotic mice. J Bone Miner Res 2004, 19:1137-1143.
    • (2004) J Bone Miner Res , vol.19 , pp. 1137-1143
    • Blin-Wakkach, C.1    Wakkach, A.2    Rochet, N.3    Carle, G.F.4
  • 64
    • 0033623876 scopus 로고    scopus 로고
    • Prostaglandin E 2 induces expression of receptor activator of nuclear factor-kappaB ligand/osteoprotegrin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency
    • Kanematsu M., Sato T., Takai H., Watanabe K., Ikeda K., Yamada Y. Prostaglandin E 2 induces expression of receptor activator of nuclear factor-kappaB ligand/osteoprotegrin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency. J Bone Miner Res 2000, 15:1321-1329.
    • (2000) J Bone Miner Res , vol.15 , pp. 1321-1329
    • Kanematsu, M.1    Sato, T.2    Takai, H.3    Watanabe, K.4    Ikeda, K.5    Yamada, Y.6
  • 65
    • 10744231154 scopus 로고    scopus 로고
    • The surface antigen CD45R identifies a population of estrogen-regulated murine marrow cells that contain osteoclast precursors
    • Katavic V., Grcevic D., Lee S.K., Kalinowski J., Jastrzebski S., Dougall W., et al. The surface antigen CD45R identifies a population of estrogen-regulated murine marrow cells that contain osteoclast precursors. Bone 2003, 32:581-590.
    • (2003) Bone , vol.32 , pp. 581-590
    • Katavic, V.1    Grcevic, D.2    Lee, S.K.3    Kalinowski, J.4    Jastrzebski, S.5    Dougall, W.6
  • 66
    • 0035192371 scopus 로고    scopus 로고
    • Generation of bone-resorbing osteoclasts from B220+ cells: its role in accelerated osteoclastogenesis due to estrogen deficiency
    • Sato T., Shibata T., Ikeda K., Watanabe K. Generation of bone-resorbing osteoclasts from B220+ cells: its role in accelerated osteoclastogenesis due to estrogen deficiency. J Bone Miner Res 2001, 16:2215-2221.
    • (2001) J Bone Miner Res , vol.16 , pp. 2215-2221
    • Sato, T.1    Shibata, T.2    Ikeda, K.3    Watanabe, K.4
  • 67
    • 29644433627 scopus 로고    scopus 로고
    • Identification of multiple osteoclast precursor populations in murine bone marrow
    • Jacquin C., Gran D.E., Lee S.K., Lorenzo J.A., Aguila H.L. Identification of multiple osteoclast precursor populations in murine bone marrow. J Bone Miner Res 2006, 21:67-77.
    • (2006) J Bone Miner Res , vol.21 , pp. 67-77
    • Jacquin, C.1    Gran, D.E.2    Lee, S.K.3    Lorenzo, J.A.4    Aguila, H.L.5
  • 68
    • 34047131111 scopus 로고    scopus 로고
    • Ovariectomy-induced bone loss occurs independently of B cells
    • Li Y., Li A., Yang X., Weitzmann M.N. Ovariectomy-induced bone loss occurs independently of B cells. J Cell Biochem 2007, 100:1370-1375.
    • (2007) J Cell Biochem , vol.100 , pp. 1370-1375
    • Li, Y.1    Li, A.2    Yang, X.3    Weitzmann, M.N.4
  • 70
    • 0028070867 scopus 로고
    • Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow
    • Masuzawa T., Miyaura C., Onoe Y., Kusano K., Ohta H., Nozawa S., et al. Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow. J Clin Invest 1994, 94:1090-1097.
    • (1994) J Clin Invest , vol.94 , pp. 1090-1097
    • Masuzawa, T.1    Miyaura, C.2    Onoe, Y.3    Kusano, K.4    Ohta, H.5    Nozawa, S.6
  • 71
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson D.M., Maraskovsky E., Billingsley W.L., Cougall W.C., Tometsko M.E., Roux E.R., et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997, 390:175-179.
    • (1997) Nature , vol.390 , pp. 175-179
    • Anderson, D.M.1    Maraskovsky, E.2    Billingsley, W.L.3    Cougall, W.C.4    Tometsko, M.E.5    Roux, E.R.6
  • 73
    • 60549102695 scopus 로고    scopus 로고
    • Osteoimmunology in rheumatic diseases
    • Schett G. Osteoimmunology in rheumatic diseases. Arthritis Res Ther 2009, 11:210.
    • (2009) Arthritis Res Ther , vol.11 , pp. 210
    • Schett, G.1
  • 74
    • 33748788554 scopus 로고    scopus 로고
    • B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease
    • Kawai T., Matsuyama T., Hosokawa Y., Makihira S., Seki M., Karimbux N.Y., et al. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol 2006, 169(3):987-998.
    • (2006) Am J Pathol , vol.169 , Issue.3 , pp. 987-998
    • Kawai, T.1    Matsuyama, T.2    Hosokawa, Y.3    Makihira, S.4    Seki, M.5    Karimbux, N.Y.6
  • 75
    • 52949152369 scopus 로고    scopus 로고
    • B-cell infiltrates induce endosteal bone formation in inflammatory arthritis
    • Hayer S., Polzer K., Brandl A., Zwerina T., Kireva T., Smolen J.S., et al. B-cell infiltrates induce endosteal bone formation in inflammatory arthritis. J Bone Miner Res 2008, 23:1650-1660.
    • (2008) J Bone Miner Res , vol.23 , pp. 1650-1660
    • Hayer, S.1    Polzer, K.2    Brandl, A.3    Zwerina, T.4    Kireva, T.5    Smolen, J.S.6
  • 77
    • 74949100969 scopus 로고    scopus 로고
    • Pathogenesis of myeloma bone disease
    • Roodman G.D. Pathogenesis of myeloma bone disease. J Cell Biochem 2010, 109:283-291.
    • (2010) J Cell Biochem , vol.109 , pp. 283-291
    • Roodman, G.D.1
  • 78
    • 0035949510 scopus 로고    scopus 로고
    • Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
    • Pearse R.N., Sordillo E.M., Yaccoby S., Wong B.R., Liau D.F., Colman N., et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A 2001, 98:11581-11586.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11581-11586
    • Pearse, R.N.1    Sordillo, E.M.2    Yaccoby, S.3    Wong, B.R.4    Liau, D.F.5    Colman, N.6
  • 79
    • 0037097587 scopus 로고    scopus 로고
    • Immunocytochemistry reveals RAANKL expression of myeloma cells
    • Sezer O., Heider U., Jakob C., Zavrski I., Eucker J., Possinger K., et al. Immunocytochemistry reveals RAANKL expression of myeloma cells. Blood 2002, 99:4646-4647.
    • (2002) Blood , vol.99 , pp. 4646-4647
    • Sezer, O.1    Heider, U.2    Jakob, C.3    Zavrski, I.4    Eucker, J.5    Possinger, K.6
  • 80
    • 24344481288 scopus 로고    scopus 로고
    • Malignant B-lymphoid cells with bone lesions express receptor activator of nuclear factor-kappaB ligand and vascular endothelial growth factor to enhance osteoclastogenesis
    • Shibata H., Abe M., Hiura K., Wilde J., Moriyama K., Sano T., et al. Malignant B-lymphoid cells with bone lesions express receptor activator of nuclear factor-kappaB ligand and vascular endothelial growth factor to enhance osteoclastogenesis. Clin Cancer Res 2005, 11:6109-6115.
    • (2005) Clin Cancer Res , vol.11 , pp. 6109-6115
    • Shibata, H.1    Abe, M.2    Hiura, K.3    Wilde, J.4    Moriyama, K.5    Sano, T.6


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