메뉴 건너뛰기




Volumn 45, Issue 7, 2013, Pages 799-803

Genome-wide association study identifies two susceptibility loci for osteosarcoma

(50)  Savage, Sharon A a   Mirabello, Lisa a   Wang, Zhaoming b   Gastier Foster, Julie M c,d   Gorlick, Richard e   Khanna, Chand a   Flanagan, Adrienne M f,g   Tirabosco, Roberto g   Andrulis, Irene L h   Wunder, Jay S h   Gokgoz, Nalan h   Patiño Garcia, Ana i   Sierrasesúmaga, Luis i   Lecanda, Fernando i   Kurucu, Nilgün j   Ilhan, Inci Ergurhan j   Sari, Neriman j   Serra, Massimo k   Hattinger, Claudia k   Picci, Piero k   more..


Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; CYCLIC AMP; METABOTROPIC RECEPTOR 4;

EID: 84879686634     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2645     Document Type: Article
Times cited : (174)

References (45)
  • 1
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program
    • Mirabello, L., Troisi, R. & Savage, S. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 115, 1531-1543 (2009).
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.2    Savage, S.3
  • 2
    • 79956263593 scopus 로고    scopus 로고
    • Height at diagnosis and birth-weight as risk factors for osteosarcoma
    • Mirabello, L. et al. Height at diagnosis and birth-weight as risk factors for osteosarcoma. Cancer Causes Control 22, 899-908 (2011).
    • (2011) Cancer Causes Control , vol.22 , pp. 899-908
    • Mirabello, L.1
  • 3
    • 85044987199 scopus 로고    scopus 로고
    • Analysis of the human tumour necrosis factor-α (TNFα) gene promoter polymorphisms in children with bone cancer
    • Patio-Garcia, A., Sotillo-Pieiro, E., Modesto, C. & Sierrases-Maga, L. Analysis of the human tumour necrosis factor-α (TNFα) gene promoter polymorphisms in children with bone cancer. J. Med. Genet. 37, 789-792 (2000).
    • (2000) J. Med. Genet. , vol.37 , pp. 789-792
    • Patio-Garcia, A.1    Sotillo-Pieiro, E.2    Modesto, C.3    Sierrases-Maga, L.4
  • 4
    • 0141992778 scopus 로고    scopus 로고
    • Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Iα1 genes and their relationship with height in children with bone cancer
    • Ruza, E., Sotillo, E., Sierrasesúmaga, L., Azcona, C. & Patiño-Garcia, A. Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Iα1 genes and their relationship with height in children with bone cancer. J. Pediatr. Hematol. Oncol. 25, 780-786 (2003).
    • (2003) J. Pediatr. Hematol. Oncol. , vol.25 , pp. 780-786
    • Ruza, E.1    Sotillo, E.2    Sierrasesúmaga, L.3    Azcona, C.4    Patiño-Garcia, A.5
  • 5
    • 34249826649 scopus 로고    scopus 로고
    • Germ-line genetic variation of TP53 in osteosarcoma
    • Savage, S.A. et al. Germ-line genetic variation of TP53 in osteosarcoma. Pediatr. Blood Cancer 49, 28-33 (2007).
    • (2007) Pediatr. Blood Cancer , vol.49 , pp. 28-33
    • Savage, S.A.1
  • 6
    • 34548078061 scopus 로고    scopus 로고
    • Analysis of genes critical for growth regulation identifies Insulin-like Growth Factor 2 Receptor variations with possible functional significance as risk factors for osteosarcoma
    • Savage, S.A. et al. Analysis of genes critical for growth regulation identifies Insulin-like Growth Factor 2 Receptor variations with possible functional significance as risk factors for osteosarcoma. Cancer Epidemiol. Biomarkers Prev. 16, 1667-1674 (2007).
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 1667-1674
    • Savage, S.A.1
  • 7
    • 37349063082 scopus 로고    scopus 로고
    • Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients
    • Koshkina, N.V. et al. Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients. J. Pediatr. Hematol. Oncol. 29, 815-821 (2007).
    • (2007) J. Pediatr. Hematol. Oncol. , vol.29 , pp. 815-821
    • Koshkina, N.V.1
  • 8
    • 66149186857 scopus 로고    scopus 로고
    • Effect of TP53 Arg72Pro and MDM2 SNP309 polymorphisms on the risk of high-grade osteosarcoma development and survival
    • Toffoli, G. et al. Effect of TP53 Arg72Pro and MDM2 SNP309 polymorphisms on the risk of high-grade osteosarcoma development and survival. Clin. Cancer Res. 15, 3550-3556 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3550-3556
    • Toffoli, G.1
  • 9
    • 77953698596 scopus 로고    scopus 로고
    • Association between TGFBR1*6A and osteosarcoma: A Chinese case-control study
    • Hu, Y.S. et al. Association between TGFBR1*6A and osteosarcoma: a Chinese case-control study. BMC Cancer 10, 169 (2010).
    • (2010) BMC Cancer , vol.10 , pp. 169
    • Hu, Y.S.1
  • 10
    • 77955395342 scopus 로고    scopus 로고
    • Genetic variation at chromosome 8q24 in osteosarcoma cases and controls
    • Mirabello, L. et al. Genetic variation at chromosome 8q24 in osteosarcoma cases and controls. Carcinogenesis 31, 1400-1404 (2010).
    • (2010) Carcinogenesis , vol.31 , pp. 1400-1404
    • Mirabello, L.1
  • 11
    • 79960137500 scopus 로고    scopus 로고
    • A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma
    • Mirabello, L. et al. A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma. BMC Cancer 11, 209 (2011).
    • (2011) BMC Cancer , vol.11 , pp. 209
    • Mirabello, L.1
  • 12
    • 79955086282 scopus 로고    scopus 로고
    • Using epidemiology and genomics to understand osteosarcoma etiology
    • Savage, S.A. & Mirabello, L. Using epidemiology and genomics to understand osteosarcoma etiology. Sarcoma 2011, 548151 (2011).
    • (2011) Sarcoma , vol.2011 , pp. 548151
    • Savage, S.A.1    Mirabello, L.2
  • 13
    • 84857640771 scopus 로고    scopus 로고
    • Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma
    • Postel-Vinay, S. et al. Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. Nat. Genet. 44, 323-327 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 323-327
    • Postel-Vinay, S.1
  • 14
    • 69349101565 scopus 로고    scopus 로고
    • Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
    • Papaemmanuil, E. et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat. Genet. 41, 1006-1010 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 1006-1010
    • Papaemmanuil, E.1
  • 15
    • 39749118602 scopus 로고    scopus 로고
    • Multiple loci identified in a genome-wide association study of prostate cancer
    • Thomas, G. et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet. 40, 310-315 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 310-315
    • Thomas, G.1
  • 16
    • 69349097813 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
    • Amundadottir, L. et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat. Genet. 41, 986-990 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 986-990
    • Amundadottir, L.1
  • 17
    • 84947899485 scopus 로고    scopus 로고
    • A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
    • Rothman, N. et al. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat. Genet. 42, 978-984 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 978-984
    • Rothman, N.1
  • 18
    • 72149129508 scopus 로고    scopus 로고
    • A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
    • Landi, M.T. et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am. J. Hum. Genet. 85, 679-691 (2009).
    • (2009) Am. J. Hum. Genet. , vol.85 , pp. 679-691
    • Landi, M.T.1
  • 19
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
    • (2007) Nature , vol.447 , pp. 661-678
  • 20
    • 84875271874 scopus 로고    scopus 로고
    • GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children
    • Li, J. et al. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Hum. Mol. Genet. 22, 1457-1464 (2013).
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 1457-1464
    • Li, J.1
  • 21
    • 83055161438 scopus 로고    scopus 로고
    • New gene functions in megakaryopoiesis and platelet formation
    • Gieger, C. et al. New gene functions in megakaryopoiesis and platelet formation. Nature 480, 201-208 (2011).
    • (2011) Nature , vol.480 , pp. 201-208
    • Gieger, C.1
  • 22
    • 84859224216 scopus 로고    scopus 로고
    • A meta-analysis and genome-wide association study of platelet count and mean platelet volume in African Americans
    • Qayyum, R. et al. A meta-analysis and genome-wide association study of platelet count and mean platelet volume in African Americans. PLoS Genet. 8, e1002491 (2012).
    • (2012) PLoS Genet. , vol.8
    • Qayyum, R.1
  • 23
    • 84864471868 scopus 로고    scopus 로고
    • Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia
    • Slager, S.L. et al. Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. Blood 120, 843-846 (2012).
    • (2012) Blood , vol.120 , pp. 843-846
    • Slager, S.L.1
  • 24
    • 67649876131 scopus 로고    scopus 로고
    • A genome-wide association study of testicular germ cell tumor
    • Rapley, E.A. et al. A genome-wide association study of testicular germ cell tumor. Nat. Genet. 41, 807-810 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 807-810
    • Rapley, E.A.1
  • 25
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium
    • 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010).
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 26
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
    • (2012) Nature , vol.489 , pp. 57-74
  • 27
    • 77956368069 scopus 로고    scopus 로고
    • Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
    • Molyneux, S.D. et al. Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. J. Clin. Invest. 120, 3310-3325 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 3310-3325
    • Molyneux, S.D.1
  • 28
    • 19944408615 scopus 로고    scopus 로고
    • A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: Comparison with Carney complex and other PRKAR1A induced lesions
    • Griffin, K.J. et al. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions. J. Med. Genet. 41, 923-931 (2004).
    • (2004) J. Med. Genet. , vol.41 , pp. 923-931
    • Griffin, K.J.1
  • 30
    • 51749088109 scopus 로고    scopus 로고
    • The role of glutamate in the regulation of bone mass and architecture
    • Skerry, T.M. The role of glutamate in the regulation of bone mass and architecture. J. Musculoskelet. Neuronal Interact. 8, 166-173 (2008).
    • (2008) J. Musculoskelet. Neuronal Interact. , vol.8 , pp. 166-173
    • Skerry, T.M.1
  • 31
    • 14944381280 scopus 로고    scopus 로고
    • Characterization of the glutametergic system in MG-63 osteoblast-like osteosarcoma cells
    • Kalariti, N., Lembessis, P. & Koutsilieris, M. Characterization of the glutametergic system in MG-63 osteoblast-like osteosarcoma cells. Anticancer Res. 24, 3923-3929 (2004).
    • (2004) Anticancer Res. , vol.24 , pp. 3923-3929
    • Kalariti, N.1    Lembessis, P.2    Koutsilieris, M.3
  • 32
    • 18244393785 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance
    • Chang, H.J. et al. Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance. Clin. Cancer Res. 11, 3288-3295 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3288-3295
    • Chang, H.J.1
  • 33
    • 77953726117 scopus 로고    scopus 로고
    • Glutamate receptors in pediatric tumors of the central nervous system
    • Brocke, K.S. et al. Glutamate receptors in pediatric tumors of the central nervous system. Cancer Biol. Ther. 9, 455-468 (2010).
    • (2010) Cancer Biol. Ther. , vol.9 , pp. 455-468
    • Brocke, K.S.1
  • 34
    • 72849112674 scopus 로고    scopus 로고
    • Expression of glutamate receptor subunits in human cancers
    • Stepulak, A. et al. Expression of glutamate receptor subunits in human cancers. Histochem. Cell Biol. 132, 435-445 (2009).
    • (2009) Histochem. Cell Biol. , vol.132 , pp. 435-445
    • Stepulak, A.1
  • 35
    • 80054750073 scopus 로고    scopus 로고
    • Silencing of selected glutamate receptor subunits modulates cancer growth
    • Luksch, H. et al. Silencing of selected glutamate receptor subunits modulates cancer growth. Anticancer Res. 31, 3181-3192 (2011).
    • (2011) Anticancer Res. , vol.31 , pp. 3181-3192
    • Luksch, H.1
  • 36
    • 66749185818 scopus 로고    scopus 로고
    • Progress in genome-wide association studies of human height
    • Hirschhorn, J.N. & Lettre, G. Progress in genome-wide association studies of human height. Horm. Res. 71 (suppl. 2), 5-13 (2009).
    • (2009) Horm. Res. , vol.71 , Issue.SUPPL. 2 , pp. 5-13
    • Hirschhorn, J.N.1    Lettre, G.2
  • 37
    • 84555190223 scopus 로고    scopus 로고
    • Improved imputation of common and uncommon SNPs with a new reference set
    • Wang, Z. et al. Improved imputation of common and uncommon SNPs with a new reference set. Nat. Genet. 44, 6-7 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 6-7
    • Wang, Z.1
  • 38
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N., Donnelly, P. & Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
    • (2009) PLoS Genet. , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 39
    • 78651257523 scopus 로고    scopus 로고
    • Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
    • Purdue, M.P. et al. Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat. Genet. 43, 60-65 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 60-65
    • Purdue, M.P.1
  • 40
    • 33845368295 scopus 로고    scopus 로고
    • SequenceLDhot: Detecting recombination hotspots
    • Fearnhead, P. SequenceLDhot: detecting recombination hotspots. Bioinformatics 22, 3061-3066 (2006).
    • (2006) Bioinformatics , vol.22 , pp. 3061-3066
    • Fearnhead, P.1
  • 41
    • 0036433716 scopus 로고    scopus 로고
    • Approximate likelihood methods for estimating local recombination rates
    • Fearnhead, P. & Donnelly, P. Approximate likelihood methods for estimating local recombination rates. J. R. Stat. Soc. Series B Stat. Methodol. 64, 657-680 (2002).
    • (2002) J. R. Stat. Soc. Series B Stat. Methodol. , vol.64 , pp. 657-680
    • Fearnhead, P.1    Donnelly, P.2
  • 42
    • 3042700117 scopus 로고    scopus 로고
    • Evidence for substantial fine-scale variation in recombination rates across the human genome
    • Crawford, D.C. et al. Evidence for substantial fine-scale variation in recombination rates across the human genome. Nat. Genet. 36, 700-706 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 700-706
    • Crawford, D.C.1
  • 43
    • 0347361674 scopus 로고    scopus 로고
    • Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data
    • Li, N. & Stephens, M. Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics 165, 2213-2233 (2003).
    • (2003) Genetics , vol.165 , pp. 2213-2233
    • Li, N.1    Stephens, M.2
  • 44
    • 34147108263 scopus 로고    scopus 로고
    • Snp.plotter: An R-based SNP/haplotype association and linkage disequilibrium plotting package
    • Luna, A. & Nicodemus, K.K. snp.plotter: an R-based SNP/haplotype association and linkage disequilibrium plotting package. Bioinformatics 23, 774-776 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 774-776
    • Luna, A.1    Nicodemus, K.K.2
  • 45
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini, J., Howie, B., Myers, S., McVean, G. & Donnelly, P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 39, 906-913 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.