Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand

BMB Reports

Volumn 46, Issue 11, 2013, Pages 544-549

  Bae, Jong Sup ^a   Rezaie, Alireza R ^b  

^a Kyungpook National University   (South Korea)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epcr; Hmgb1; Par 1; Protein C; Thrombin

Indexed keywords

CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LEUKOCYTE ANTIGEN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE P38; PROCR PROTEIN, HUMAN; PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ADHESION; CELL MEMBRANE PERMEABILITY; CELL MOTION; DOWN REGULATION; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIGENS, CD; CELL ADHESION; CELL ADHESION MOLECULES; CELL MEMBRANE PERMEABILITY; CELL MOVEMENT; DOWN-REGULATION; HMGB1 PROTEIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; LIGANDS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN C; RECEPTOR, PAR-1; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; THROMBIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890153581     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2013.46.11.056     Document Type: Article

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