The effects of proinflammatory cytokines on cytokine-chemokine gene expression profiles in the human corneal endothelium

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 2, 2003, Pages 514-520

  Yamagami, Hiroko ^a   Yamagami, Satoru ^b   Inoki, Taeko ^a   Amano, Shiro ^b   Miyata, Kazunori ^c  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Miyata Eye Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE; COMPLEMENTARY DNA; CYTOKINE; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA MICROARRAY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELLS, CULTURED; CHEMOKINES; CYTOKINES; DNA, COMPLEMENTARY; ENDOTHELIUM, CORNEAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; INTERLEUKIN-1; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0037308613     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0498     Document Type: Article

References (45)

1. Sakai R, Kinouchi T, Kawamoto S, et al. Construction of human corneal endothelial cDNA library and identification of novel active genes. Invest Ophthalmol Vis Sci. 2002;43:1749-1756.
2. Bouchard CS. The ocular immune response. In: Krachmer JH, Mannis MJ, Holland EJ, ed. Cornea, St. Louis: Mosby; 1997;68-127.
3. Williams JM, Fini ME, Cousins SW, Pepose JS. Corneal responses to infection. In: Krachmer JH, Mannis MJ, Holland EJ, ed. Cornea, St. Louis: Mosby; 1997;129-162.
4. Wilson SE, Schultz GS, Chegini N, Weng J, He Y-G. Epidermal growth factor, transforming growth factor alpha, transforming growth factor beta, acidic fibroblast growth factor, basic fibroblast growth factor, and interleukin-1 proteins in the cornea. Exp Eye Res. 1994;59:63-72.
5. Wilson SE, He YG, Lloyd SA. EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts. Invest Ophthalmol Vis Sci. 1992;33:1756-1765.
6. Staats HF, Lausch RN. Cytokine expression in vivo during murine herpetic stromal keratitis: effect of protective antibody therapy. J Immunol. 1993;151:277-283.
7. Sekine-Okano M, Lucas R, Rungger D, et al. Expression and release of tumor necrosis factor-alpha by explants of mouse cornea. Invest Opthalmol Vis Sci. 1996;37:1302-1310.
8. Brito BE, O'Rourke LM, Pan Y, Anglin J, Planck SR, Rosenbaum JT. IL-1 and TNF receptor-deficient mice show decreased inflammation in an immune complex model of uveitis. Invest Ophthalmol Vis Sci. 1999;40:2583-2589.
9. Mo JS, Matsukawa A, Ohkawara S, Yoshinaga M. Involvement of TNF alpha, IL-1 beta and IL-1 receptor antagonist in LPS-induced rabbit uveitis. Exp Eye Res. 1998;66:547-557.
10. Yoshida M, Yoshimura N, Hangai M, Tanihara H, Honda Y. Interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1994;35:1107-1113.
11. Keadle TL, Usui N, Laycock KA, Miller JK, Pepose JS, Stuart PM. IL-1 and TNF-alpha are important factors in the pathogenesis of murine recurrent herpetic stromal keratitis. Invest Ophthalmol Vis Sci. 2000;41:96-102.
12. Thomas J, Kanangat S, Rouse BT. Herpes simplex virus replication-induced expression of chemokines and proinflammatory cytokines in the eye: implications in herpetic stromal keratitis. J Interferon Cytokine Res. 1998;18:681-690.
13. Sano Y, Osawa H, Sotozono C, Kinoshita S. Cytokine expression during orthotopic corneal allograft rejection in mice. Invest Ophthalmol Vis Sci. 1998;39:1953-1957.
14. Zhu S, Dekaris I, Duncker G, Dana MR. Early expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-α after corneal transplantation. J Interferon Cytokine Res. 1999;19:661-669.
15. Miyata K, Drake J, Osakabe Y, et al. Effect of donor age on morphologic variation of cultured human corneal endothelial cells. Cornea. 2001;20:59-63.
16. Luther SA, Cyster JG. Chemokines as regulators of T cell differentiation. Nat Immunol. 2001;2:102-107.
17. Tangirala RK, Murao K, Quehenberger O. Regulation of expression of the human monocyte chemotactic protein-1 receptor (hCCR2) by cytokines. J Biol Chem. 1997;272:8050-8056.
18. Tran MT, Tellaetxe-Isusi M, Elner V, Strieter RM, Lausch RN, Oakes JE. Proinflammatory cytokines induce RANTES and MCP-1 synthesis in human corneal keratocytes but not in corneal epithelial cells: beta-chemokine synthesis in corneal cells. Invest Ophthalmol Vis Sci. 1996;37:987-996.
19. Hong JW, Lin JJ, Lee JS, et al. Proinflammatory chemokine induction in keratocytes and inflammatory cell infiltration into the cornea. Invest Ophthalmol Vis Sci. 2001;42:2795-2803.
20. Luster AD. Chemokines-chemotactic cytokines that mediate inflammation. N Engl J Med. 1998;338:436-445.
21. Elner VM, Strieter RM, Pavilack MA, et al. Human corneal interleukin-8. IL-1 and TNF-induced gene-expression and secretion. Am J Pathol. 1991;139:977-988.
22. Chodosh J, Astley RA, Butler MG, Kennedy RC. Adenovirus keratitis: a role for interleukin-8. Invest Ophthalmol Vis Sci. 2000; 41:783-789.
23. Xue ML, Willcox MD, Lloyd A, Wakefield D, Thakur A. Regulatory role of IL-1 beta in the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colonization. Clin Exp Ophthalmol. 2001;29:171-174.
24. Kernacki KA, Barrett RP, Hobden JA, Hazlett LD. Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx in ocular bacterial infection. J Immunol. 2000;164:1037-1045.
25. Yan XT, Tumpey TM, Kunkel SL, Oakes JE, Lausch RN. Role of MIP-2 in neutrophil migration and tissue injury in the herpes simplex virus-1-infected cornea. Invest Opthalmol Vis Sci. 1998; 39:1854-1862.
26. Cubitt CL, Tang Q, Monteiro CA, Lausch RN, Oakes JE. IL-8 gene expression in cultures of human corneal epithelial cells and keratocytes. Invest Opthalmol Vis Sci. 1993;34:3199-3206.
27. Cubitt CL, Lausch RN, Oakes JE. Differential induction of GRO alpha gene expression in human corneal epithelial cells and keratocytes exposed to proinflammatory cytokines. Invest Ophthalmol Vis Sci. 1997;38:1149-1158.
28. Hall LR, Diaconu E, Patel R, Pearlman E. CXC chemokine receptor 2 but not C-C chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness). J Immunol. 2001;166:4035-4041.
29. Hirano T, Akira S, Taga T, Kishimoto T. Biological and clinical aspects of interleukin 6. Immunol Today. 1990;12:443-449.
30. Murray PI, Hoekzema R, van Haren MA, de Hon FD, Kijlstra A. Aqueous humor interleukin-6 levels in uveitis. Invest Ophthalmol Vis Sci. 1990;31:917-920.
31. Norose K, Yano A, Wang XC, et al. Dominance of activated T cells and interleukin-6 in aqueous humor in Vogt-Koyanagi-Harada disease. Invest Ophthalmol Vis Sci. 1994;35:33-39.
32. De Vos AF, van Haren MA, Verhargen C, Hoekzema R, Kijilstra A. Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis in the rat. Invest Ophthalmol Vis Sci. 1994;35:1100-1106.
33. Ohta K, Yamagami S, Taylor A, Streilein JW. IL-6 antagonizes TGF-β and abolishes immune privilege in eyes with endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 2000;41:2591-2599.
34. Ohta K, Wiggert B, Yamagami S, Taylor AW, Streilein JW. Analysis of immunomodulatory activities of aqueous humor from eyes of mice with experimental autoimmune uveitis. J Immunol. 2000; 164:1185-1192.
35. Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW. Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood. 1994;83:113-118.
36. Marinkovic S, Jahreis JP, Wong GG, Baumann M. IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo. J Immunol. 1989;142:808-812.
37. Kriesel JD, Ricigliano J, Spruance SL, Garza HH Jr, Hill JM. Neuronal reactivation of herpes simplex virus may involve interleukin-6. J Neurovirol. 1997;3:441-448.
38. Amano S, Oshika T, Kaji Y, Numaga J, Matsubara M, Araie M. Herpes simplex virus in the trabecula of an eye with corneal endotheliitis. Am J Ophthalmol. 1999;127:721-722.
39. Holland EJ, Schwartz GS. Classification of herpes simplex virus keratitis. Cornea. 1999;18:144-154.
40. Mimura T, Amano S, Nagahara M, et al. Corneal endotheliitis and idiopathic sudden sensorineural hearing loss. Am J Ophthalmol. 2002;133:699-700.
41. Zheng X, Yamaguchi M, Goto T, Okamoto S, Ohashi Y. Experimental corneal endotheliitis in rabbit. Invest Ophthalmol Vis Sci. 2000;41:377-385.
42. Spalton DJ. Intraocular inflammation. In: Spalton DJF, Hitchings RA, Hunter PA, eds. Atlas of Clinical Ophthalmology Philadelphia: JB Lippincott; 1984;10.4.
43. Sakamoto T, Takahira K, Sanui H, Kohno T, Inomata H. Intercellular adhesion molecule-1 on rat corneal endothelium in experimental uveitis. Exp Eye Res. 1993;56:241-246.
44. Gerszten RE, Garcia-Zepeda EA, Lim YC, et al. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature. 1999;398:718-723.
45. Philipp W. Leukocyte adhesion molecules in rejected corneal allografts. Graefes Arch Clin Exp Ophthalmol. 1994;232:87-95.