Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand

Thrombosis and Haemostasis

Volumn 100, Issue 1, 2008, Pages 101-109

  Bae, Jong Sup ^a   Rezaie, Alireza R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

APC; EPCR; Inflammation; PAR 1; Signaling; Thrombin

Indexed keywords

ACTIVATED PROTEIN C; CAVEOLIN 1; ENDOTHELIAL PROTEIN C RECEPTOR; LIPOPOLYSACCHARIDE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; SMALL INTERFERING RNA; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN FUNCTION; PULMONARY ARTERY; SIGNAL TRANSDUCTION;

ANTIGENS, CD; APOPTOSIS; BETA-CYCLODEXTRINS; CAPILLARY PERMEABILITY; CAVEOLIN 1; CELL ADHESION; CELL LINE, TUMOR; CELLS, CULTURED; CHOLESTEROL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIGANDS; LIPOPOLYSACCHARIDES; MEMBRANE MICRODOMAINS; MONOCYTES; MUTATION; PEPTIDES; PROTEIN C; PULMONARY ARTERY; RECEPTOR, PAR-1; RECEPTORS, CELL SURFACE; RECEPTORS, LYSOSPHINGOLIPID; RECEPTORS, THROMBIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 46749084607     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-02-0127     Document Type: Article

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