메뉴 건너뛰기




Volumn 27, Issue 1, 2014, Pages 56-62

Integrated approaches to understanding antipsychotic drug action at GPCRs

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; CLOZAPINE; G PROTEIN COUPLED RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; QUINPIROLE; RISPERIDONE; TRANSCRIPTOME;

EID: 84890139617     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.11.002     Document Type: Review
Times cited : (21)

References (80)
  • 1
    • 0023161081 scopus 로고
    • Perspectives on the discovery of central monoaminergic neurotransmission
    • Carlsson A. Perspectives on the discovery of central monoaminergic neurotransmission. Annu Rev Neurosci 1987, 10:19-40.
    • (1987) Annu Rev Neurosci , vol.10 , pp. 19-40
    • Carlsson, A.1
  • 2
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov R.R., Wetsel W.C., Jones S.R., Levin E.D., Jaber M., Caron M.G. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 1999, 283:397-401.
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1    Wetsel, W.C.2    Jones, S.R.3    Levin, E.D.4    Jaber, M.5    Caron, M.G.6
  • 3
    • 73049129373 scopus 로고
    • The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia
    • Birkmayer W., Hornykiewicz O. The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia. Wien Klin Wochenschr 1961, 73:787-788.
    • (1961) Wien Klin Wochenschr , vol.73 , pp. 787-788
    • Birkmayer, W.1    Hornykiewicz, O.2
  • 4
    • 0034049108 scopus 로고    scopus 로고
    • Depression: the case for a monoamine deficiency
    • Delgado P.L. Depression: the case for a monoamine deficiency. J Clin Psychiatry 2000, 61(Suppl 6):7-11.
    • (2000) J Clin Psychiatry , vol.61 , Issue.SUPPL 6 , pp. 7-11
    • Delgado, P.L.1
  • 5
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: a review and reconceptualization
    • Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 1991, 148:1474-1486.
    • (1991) Am J Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 7
    • 0742271350 scopus 로고    scopus 로고
    • What's atypical about atypical antipsychotic drugs?
    • Meltzer H.Y. What's atypical about atypical antipsychotic drugs?. Curr Opin Pharmacol 2004, 4:53-57.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 53-57
    • Meltzer, H.Y.1
  • 8
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I., Burt D.R., Snyder S.H. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 1976, 192:481-483.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 9
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P., Lee T., Chau-Wong M., Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 1976, 261:717-719.
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 10
    • 0024466603 scopus 로고
    • Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
    • Meltzer H.Y., Matsubara S., Lee J.C. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther 1989, 251:238-246.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 238-246
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 12
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • Miyamoto S., Duncan G.E., Marx C.E., Lieberman J.A. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005, 10:79-104.
    • (2005) Mol Psychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 13
    • 80052957231 scopus 로고    scopus 로고
    • Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease
    • McFarland K., Price D.L., Bonhaus D.W. Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease. Behav Pharmacol 2011, 22:681-692.
    • (2011) Behav Pharmacol , vol.22 , pp. 681-692
    • McFarland, K.1    Price, D.L.2    Bonhaus, D.W.3
  • 14
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon M.I., Strathmann M.P., Gautam N. Diversity of G proteins in signal transduction. Science 1991, 252:802-808.
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 16
    • 0027156068 scopus 로고
    • Measurement of intracellular calcium using bioluminescent aequorin expressed in human cells
    • Sheu Y.A., Kricka L.J., Pritchett D.B. Measurement of intracellular calcium using bioluminescent aequorin expressed in human cells. Anal Biochem 1993, 209:343-347.
    • (1993) Anal Biochem , vol.209 , pp. 343-347
    • Sheu, Y.A.1    Kricka, L.J.2    Pritchett, D.B.3
  • 17
    • 0033230031 scopus 로고    scopus 로고
    • Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay
    • Fitzgerald L.R., Mannan I.J., Dytko G.M., Wu H.L., Nambi P. Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay. Anal Biochem 1999, 275:54-61.
    • (1999) Anal Biochem , vol.275 , pp. 54-61
    • Fitzgerald, L.R.1    Mannan, I.J.2    Dytko, G.M.3    Wu, H.L.4    Nambi, P.5
  • 20
    • 0033524455 scopus 로고    scopus 로고
    • A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins
    • Xu Y., Piston D.W., Johnson C.H. A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins. Proc Natl Acad Sci U S A 1999, 96:151-156.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 151-156
    • Xu, Y.1    Piston, D.W.2    Johnson, C.H.3
  • 21
  • 23
    • 22344431960 scopus 로고    scopus 로고
    • Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia
    • Newman-Tancredi A., Assie M.B., Leduc N., Ormiere A.M., Danty N., Cosi C. Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia. Int J Neuropsychopharmacol 2005, 8:341-356.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 341-356
    • Newman-Tancredi, A.1    Assie, M.B.2    Leduc, N.3    Ormiere, A.M.4    Danty, N.5    Cosi, C.6
  • 24
    • 79961166634 scopus 로고    scopus 로고
    • Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties
    • Newman-Tancredi A., Kleven M.S. Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties. Psychopharmacology (Berl) 2011, 216:451-473.
    • (2011) Psychopharmacology (Berl) , vol.216 , pp. 451-473
    • Newman-Tancredi, A.1    Kleven, M.S.2
  • 25
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz R.J., Shenoy S.K. Transduction of receptor signals by beta-arrestins. Science 2005, 308:512-517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 26
    • 0025352299 scopus 로고
    • Beta-Arrestin: a protein that regulates beta-adrenergic receptor function
    • Lohse M.J., Benovic J.L., Codina J., Caron M.G., Lefkowitz R.J. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science 1990, 248:1547-1550.
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 27
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
    • Ferguson S.S., Downey W.E., Colapietro A.M., Barak L.S., Menard L., Caron M.G. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 1996, 271:363-366.
    • (1996) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3    Barak, L.S.4    Menard, L.5    Caron, M.G.6
  • 29
    • 0037088585 scopus 로고    scopus 로고
    • Beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
    • Tohgo A., Pierce K.L., Choy E.W., Lefkowitz R.J., Luttrell L.M. beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J Biol Chem 2002, 277:9429-9436.
    • (2002) J Biol Chem , vol.277 , pp. 9429-9436
    • Tohgo, A.1    Pierce, K.L.2    Choy, E.W.3    Lefkowitz, R.J.4    Luttrell, L.M.5
  • 30
    • 4143070533 scopus 로고    scopus 로고
    • Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
    • Ahn S., Shenoy S.K., Wei H., Lefkowitz R.J. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J Biol Chem 2004, 279:35518-35525.
    • (2004) J Biol Chem , vol.279 , pp. 35518-35525
    • Ahn, S.1    Shenoy, S.K.2    Wei, H.3    Lefkowitz, R.J.4
  • 31
    • 0033527663 scopus 로고    scopus 로고
    • Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
    • Oakley R.H., Laporte S.A., Holt J.A., Barak L.S., Caron M.G. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 1999, 274:32248-32257.
    • (1999) J Biol Chem , vol.274 , pp. 32248-32257
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 32
    • 34447649922 scopus 로고    scopus 로고
    • Beta-arrestin-biased ligands at seven-transmembrane receptors
    • Violin J.D., Lefkowitz R.J. Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 2007, 28:416-422.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 416-422
    • Violin, J.D.1    Lefkowitz, R.J.2
  • 35
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu J.M., Sotnikova T.D., Marion S., Lefkowitz R.J., Gainetdinov R.R., Caron M.G. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 2005, 122:261-273.
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 36
    • 51649084026 scopus 로고    scopus 로고
    • Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics
    • Masri B., Salahpour A., Didriksen M., Ghisi V., Beaulieu J.M., Gainetdinov R.R., Caron M.G. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci U S A 2008, 105:13656-13661.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13656-13661
    • Masri, B.1    Salahpour, A.2    Didriksen, M.3    Ghisi, V.4    Beaulieu, J.M.5    Gainetdinov, R.R.6    Caron, M.G.7
  • 38
    • 0035896585 scopus 로고    scopus 로고
    • The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis
    • Bhatnagar A., Willins D.L., Gray J.A., Woods J., Benovic J.L., Roth B.L. The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis. J Biol Chem 2001, 276:8269-8277.
    • (2001) J Biol Chem , vol.276 , pp. 8269-8277
    • Bhatnagar, A.1    Willins, D.L.2    Gray, J.A.3    Woods, J.4    Benovic, J.L.5    Roth, B.L.6
  • 39
    • 38949210817 scopus 로고    scopus 로고
    • Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo
    • Schmid C.L., Raehal K.M., Bohn L.M. Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo. Proc Natl Acad Sci U S A 2008, 105:1079-1084.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 1079-1084
    • Schmid, C.L.1    Raehal, K.M.2    Bohn, L.M.3
  • 40
    • 67049136336 scopus 로고    scopus 로고
    • Overview of animal models of schizophrenia
    • Chapter 9: Unit 9
    • Powell S.B., Geyer M.A. Overview of animal models of schizophrenia. Curr Protoc Neurosci 2007, 24. Chapter 9: Unit 9.
    • (2007) Curr Protoc Neurosci , pp. 24
    • Powell, S.B.1    Geyer, M.A.2
  • 41
    • 77749279516 scopus 로고    scopus 로고
    • Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects
    • van den Buuse M. Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects. Schizophr Bull 2010, 36:246-270.
    • (2010) Schizophr Bull , vol.36 , pp. 246-270
    • van den Buuse, M.1
  • 43
    • 0021263575 scopus 로고
    • Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats
    • Weiner I., Lubow R.E., Feldon J. Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats. Psychopharmacology (Berl) 1984, 83:194-199.
    • (1984) Psychopharmacology (Berl) , vol.83 , pp. 194-199
    • Weiner, I.1    Lubow, R.E.2    Feldon, J.3
  • 44
    • 0031962988 scopus 로고    scopus 로고
    • Drug treatment of the negative symptoms of schizophrenia
    • King D.J. Drug treatment of the negative symptoms of schizophrenia. Eur Neuropsychopharmacol 1998, 8:33-42.
    • (1998) Eur Neuropsychopharmacol , vol.8 , pp. 33-42
    • King, D.J.1
  • 45
    • 11844286960 scopus 로고    scopus 로고
    • Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies
    • Abi-Dargham A., Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. Eur Psychiatry 2005, 20:15-27.
    • (2005) Eur Psychiatry , vol.20 , pp. 15-27
    • Abi-Dargham, A.1    Laruelle, M.2
  • 47
    • 32344435859 scopus 로고    scopus 로고
    • Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning
    • Kellendonk C., Simpson E.H., Polan H.J., Malleret G., Vronskaya S., Winiger V., Moore H., Kandel E.R. Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron 2006, 49:603-615.
    • (2006) Neuron , vol.49 , pp. 603-615
    • Kellendonk, C.1    Simpson, E.H.2    Polan, H.J.3    Malleret, G.4    Vronskaya, S.5    Winiger, V.6    Moore, H.7    Kandel, E.R.8
  • 48
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B., Jaber M., Jones S.R., Wightman R.M., Caron M.G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 1996, 379:606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 49
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn A.R., Gainetdinov R.R., Caron M.G., Koller B.H. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 1999, 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 50
    • 77953410624 scopus 로고    scopus 로고
    • Gene models of schizophrenia: DISC1 mouse models
    • Jaaro-Peled H. Gene models of schizophrenia: DISC1 mouse models. Prog Brain Res 2009, 179:75-86.
    • (2009) Prog Brain Res , vol.179 , pp. 75-86
    • Jaaro-Peled, H.1
  • 52
    • 2342580148 scopus 로고    scopus 로고
    • Neurotensin, schizophrenia, and antipsychotic drug action
    • Kinkead B., Nemeroff C.B. Neurotensin, schizophrenia, and antipsychotic drug action. Int Rev Neurobiol 2004, 59:327-349.
    • (2004) Int Rev Neurobiol , vol.59 , pp. 327-349
    • Kinkead, B.1    Nemeroff, C.B.2
  • 53
    • 38949207272 scopus 로고    scopus 로고
    • The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity
    • Woolley M.L., Pemberton D.J., Bate S., Corti C., Jones D.N. The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity. Psychopharmacology (Berl) 2008, 196:431-440.
    • (2008) Psychopharmacology (Berl) , vol.196 , pp. 431-440
    • Woolley, M.L.1    Pemberton, D.J.2    Bate, S.3    Corti, C.4    Jones, D.N.5
  • 54
    • 84873414007 scopus 로고    scopus 로고
    • Alternative pharmacologic targets for the treatment of schizophrenia: results from phase I and II trials
    • Miyamoto S., Jarskog L.F., Fleischhacker W.W. Alternative pharmacologic targets for the treatment of schizophrenia: results from phase I and II trials. Curr Opin Psychiatry 2013, 26:158-165.
    • (2013) Curr Opin Psychiatry , vol.26 , pp. 158-165
    • Miyamoto, S.1    Jarskog, L.F.2    Fleischhacker, W.W.3
  • 55
    • 84869089143 scopus 로고    scopus 로고
    • Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain
    • McOmish C.E., Lira A., Hanks J.B., Gingrich J.A. Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain. Neuropsychopharmacology 2012, 37:2747-2755.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2747-2755
    • McOmish, C.E.1    Lira, A.2    Hanks, J.B.3    Gingrich, J.A.4
  • 57
    • 0036848588 scopus 로고    scopus 로고
    • Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice
    • Ralph-Williams R.J., Lehmann-Masten V., Otero-Corchon V., Low M.J., Geyer M.A. Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice. J Neurosci 2002, 22:9604-9611.
    • (2002) J Neurosci , vol.22 , pp. 9604-9611
    • Ralph-Williams, R.J.1    Lehmann-Masten, V.2    Otero-Corchon, V.3    Low, M.J.4    Geyer, M.A.5
  • 60
    • 33644748177 scopus 로고    scopus 로고
    • Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens
    • Lee K.W., Kim Y., Kim A.M., Helmin K., Nairn A.C., Greengard P. Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proc Natl Acad Sci U S A 2006, 103:3399-3404.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 3399-3404
    • Lee, K.W.1    Kim, Y.2    Kim, A.M.3    Helmin, K.4    Nairn, A.C.5    Greengard, P.6
  • 61
    • 34548651693 scopus 로고    scopus 로고
    • Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    • Gong S., Doughty M., Harbaugh C.R., Cummins A., Hatten M.E., Heintz N., Gerfen C.R. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci 2007, 27:9817-9823.
    • (2007) J Neurosci , vol.27 , pp. 9817-9823
    • Gong, S.1    Doughty, M.2    Harbaugh, C.R.3    Cummins, A.4    Hatten, M.E.5    Heintz, N.6    Gerfen, C.R.7
  • 63
    • 0035798093 scopus 로고    scopus 로고
    • The neurobiology of slow synaptic transmission
    • Greengard P. The neurobiology of slow synaptic transmission. Science 2001, 294:1024-1030.
    • (2001) Science , vol.294 , pp. 1024-1030
    • Greengard, P.1
  • 64
    • 48149108931 scopus 로고    scopus 로고
    • Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
    • Bateup H.S., Svenningsson P., Kuroiwa M., Gong S., Nishi A., Heintz N., Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nat Neurosci 2008, 11:932-939.
    • (2008) Nat Neurosci , vol.11 , pp. 932-939
    • Bateup, H.S.1    Svenningsson, P.2    Kuroiwa, M.3    Gong, S.4    Nishi, A.5    Heintz, N.6    Greengard, P.7
  • 65
    • 84874407555 scopus 로고    scopus 로고
    • Deletion of GSK3beta in D2R-expressing neurons reveals distinct roles for beta-arrestin signaling in antipsychotic and lithium action
    • Urs N.M., Snyder J.C., Jacobsen J.P., Peterson S.M., Caron M.G. Deletion of GSK3beta in D2R-expressing neurons reveals distinct roles for beta-arrestin signaling in antipsychotic and lithium action. Proc Natl Acad Sci U S A 2012, 109:20732-20737.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 20732-20737
    • Urs, N.M.1    Snyder, J.C.2    Jacobsen, J.P.3    Peterson, S.M.4    Caron, M.G.5
  • 68
    • 0029763907 scopus 로고    scopus 로고
    • Serotonergic mechanisms in neuroleptic-induced catalepsy in the rat
    • Wadenberg M.L. Serotonergic mechanisms in neuroleptic-induced catalepsy in the rat. Neurosci Biobehav Rev 1996, 20:325-339.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 325-339
    • Wadenberg, M.L.1
  • 74
    • 18044370446 scopus 로고    scopus 로고
    • Antipsychotic drugs elevate mRNA levels of presynaptic proteins in the frontal cortex of the rat
    • MacDonald M.L., Eaton M.E., Dudman J.T., Konradi C. Antipsychotic drugs elevate mRNA levels of presynaptic proteins in the frontal cortex of the rat. Biol Psychiatry 2005, 57:1041-1051.
    • (2005) Biol Psychiatry , vol.57 , pp. 1041-1051
    • MacDonald, M.L.1    Eaton, M.E.2    Dudman, J.T.3    Konradi, C.4
  • 76
  • 79
    • 7244238404 scopus 로고    scopus 로고
    • Promiscuous protein biotinylation by Escherichia coli biotin protein ligase
    • Choi-Rhee E., Schulman H., Cronan J.E. Promiscuous protein biotinylation by Escherichia coli biotin protein ligase. Protein Sci 2004, 13:3043-3050.
    • (2004) Protein Sci , vol.13 , pp. 3043-3050
    • Choi-Rhee, E.1    Schulman, H.2    Cronan, J.E.3
  • 80
    • 84860270506 scopus 로고    scopus 로고
    • A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
    • Roux K.J., Kim D.I., Raida M., Burke B. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. J Cell Biol 2012, 196:801-810.
    • (2012) J Cell Biol , vol.196 , pp. 801-810
    • Roux, K.J.1    Kim, D.I.2    Raida, M.3    Burke, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.