Evaluation of CK2 inhibitor (E)-3-(2,3,4,5-tetrabromophenyl)acrylic acid (TBCA) in regulation of platelet function

European Journal of Pharmacology

Volumn 720, Issue 1-3, 2013, Pages 391-400

  Ryu, Si Yun ^a   Kim, Soochong ^b  

^a Chungnam National University   (South Korea)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; CK2; PI 3 kinase; Platelet; Thromboxane

Indexed keywords

2 METHYLTHIOADENOSINE DIPHOSPHATE; 3 (2,3,4,5 TETRABROMOPHENYL)ACRYLIC ACID; ADENOSINE DERIVATIVE; ALPHA3 INTEGRIN; CASEIN KINASE II; COLLAGEN RELATED PEPTIDE; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 4 AGONIST PEPTIDE; THROMBIN RECEPTOR ACTIVATING PEPTIDE; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE A2; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CLOT RETRACTION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RELEASE REACTION;

AKT; CK2; PI 3-KINASE; PLATELET; THROMBOXANE;

ACRYLATES; BLOOD PLATELETS; CASEIN KINASE II; CELLS, CULTURED; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; THROMBOXANE A2;

EID: 84890118519     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.09.064     Document Type: Article

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