Protein kinase CK2 - A key suppressor of apoptosis

Advances in Enzyme Regulation

Volumn 48, Issue 1, 2008, Pages 179-187

  Ahmad, Kashif A ^a   Wang, Guixia ^a   Unger, Gretchen ^a   Slaton, Joel ^a   Ahmed, Khalil ^a  

^a VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE II;

ANIMAL; APOPTOSIS; ARTICLE; DOWN REGULATION; DRUG EFFECT; HUMAN; NEOPLASM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CASEIN KINASE II; DOWN-REGULATION; HUMANS; NEOPLASMS;

EID: 50649124915     PISSN: 00652571     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.advenzreg.2008.04.002     Document Type: Article

References (86)

1. Ahmad K.A., Harris N.H., Johnson A.D., Lindvall H.C.N., Wang G., and Ahmed K. Protein kinase CK2 modulates apoptosis induced by resveratrol and EGCG in prostate cancer cells. Mol Cancer Therap 6 (2007) 1006-1012
2. Ahmad K.A., Wang G., and Ahmed K. Intracellular hydrogen peroxide production is an upstream event in apoptosis induced by downregulation of CK2 in prostate cancer cells. Mol Cancer Res 4 (2006) 331-338
3. Ahmad K.A., Wang G., Slaton J., Unger G., and Ahmed K. Targeting CK2 for cancer therapy. Anti-Cancer Drugs 16 (2005) 1037-1044
4. Ahmed K. Nuclear matrix and protein kinase CK2 signaling. Crit Rev Eukaryot Gene Expr 9 (1999) 329-336
5. Ahmed K., Davis A.T., Wang H., Faust R.A., Yu S., and Tawfic S. Significance of protein kinase CK2 nuclear signaling in neoplasia. J Cell Biochem Suppl 35 (2000) 130-135
6. Ahmed K., Gerber D.A., and Cochet C. Joining the cell survival squad: an emerging role for protein kinase CK2. Trends in Cell Biology 12 (2002) 226-230
7. Ahmed K., and Ishida H. Effects of testosterone on nuclear phosphoproteins of rat ventral prostate. Mol Pharmacol 7 (1971) 323-327
8. Ahmed K., Yenice S., Davis A., and Goueli S.A. Association of casein kinase 2 (CK-2) with nuclear chromatin in relation to androgenic regulation of rat prostate. Proc Natl Acad Sci U S A 90 (1993) 4426-4430
9. Allende J.E., and Allende C.C. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J 9 (1995) 313-323
10. Bouchou T., Vernet M., Blond O., Jensen H.H., Pointou H., Olsen B.B., et al. Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality. Mol Cell Biol 23 (2003) 908-915
11. Channavajhala P., and Seldin D.C. Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene 21 (2002) 5280-5288
12. Cobb L., Koyama S., and Cohen P. Site-specific phosphorylation by intracellular kinases determines the apoptotic activity of IGFBP-3 in prostate cancer. Los Angeles, CA. AACR annual meeting proceedings (2007) Abstract #4393
13. Davis A.T., Wang H., Zhang P., and Ahmed K. Heat shock mediated modulation of protein kinase CK2 in the nuclear matrix. J Cell Biochem 85 (2002) 583-591
14. Desagher S., Osen-Sand A., Montessuit S., Magnenat E., Vilbois F., Hochmann A., et al. Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. Mol Cell 8 (2001) 601-611
15. Di Maira G., Brustolon F., Bertacchini J., Tosoni K., Marmiroli S., Pinna L.A., et al. Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level. Oncogene (2007) Epub ahead of print
16. Di Maira G., Salvi M., Arrigoni G., Marin O., Sarno S., Brustolon F., et al. Protein kinase CK2 phosphorylates and upregulates Akt/PKB. Cell Death Differ 12 (2005) 668-677
17. Eddy S.F., Guo S., Demicco E.G., Romieu-Mourez R., Landesman-Bollag E., Seldin D.C., et al. Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells. Cancer Res 65 (2005) 11375-11383
18. Faust M., and Montenarh M. Subcellular localization of protein kinase CK2 - a key to its function?. Cell & Tissue Res 301 (2000) 329-340
19. Faust R.A., Gapany M., Tristani P., Davis A., Adams G.L., and Ahmed K. Elevated protein kinase CK2 activity in chromatin of head and neck tumors: association with malignant transformation. Cancer Lett 101 (1996) 31-35
20. Faust R.A., Niehans G., Gapany M., Knapp D., Cherwitz D., Davis A., et al. Subcellular immunolocalization of protein kinase CK2 in squamous cell carcinomas of the head and neck. Int J Biochem Cell Biol 31 (1999) 941-949
21. Faust R.A., Tawfic S., Davis A.T., Bubash L.A., and Ahmed K. Antisense oligodeoxynucleotides against protein kinase CK2α inhibit growth of squamous cell carcinoma of head and neck. in vitro. Head Neck 22 (2000) 341-346
22. Filhol O., Martiel J.-L., and Cochet C. Protein kinase CK2: a new view of an old molecular complex. EMBO Rep 5 (2004) 351-355
23. Gapany M., Faust R.A., Tawfic S., Davis A., Adams G., and Ahmed K. Association of elevated protein kinase CK2 activity with aggressive behavior of squamous cell carcinoma of the head and neck. Molec Med 1 (1995) 659-666
24. Goueli S., and Ahmed K. Nature of intrinsic protein kinases involved in phosphorylation of non-histone proteins in intact prostatic nuclei: further identification of androgen-sensitive protein kinase reaction. Mol Cell Biochem 101 (1991) 145-155
25. Graham K.C., and Litchfield D.W. The regulatory β subunit of protein kinase CK2 mediates formation of tetrameric CK2 complexes. J Biol Chem 275 (2000) 5003-5010
26. Guerra B. Protein kinase CK2 subunits are positive regulators of AKT kinase. Int J Oncol 28 (2006) 685-693
27. Guerra B., and Issinger O.-G. Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis 20 (1999) 391-408
28. Guerra B., Siemer S., Boldyreff B., and Issinger O.G. Protein kinase CK2: evidence for a proteinase CK2β subunit fraction, devoid of the catalytic CK2α subunit in mouse brain and testicles. FEBS Lett 462 (1999) 353-357
29. Guo C., Davis A.T., and Ahmed K. Dynamics of protein kinase CK2 association with nucleosomes in relation to transcriptional activity. J Biol Chem 273 (1998) 13675-13680
30. Guo C., Davis A.T., Yu S., Tawfic S., and Ahmed K. Role of protein kinase CK2 in phosphorylation of nucleosomal proteins in relation to transcriptional activity. Mol Cell Biochem 191 (1999) 135-142
31. Guo C., Yu S., Davis A.T., and Ahmed K. Nuclear matrix targeting of the protein kinase CK2 signal as common downstream response to androgen or growth factor stimulation of prostate cancer cells. Cancer Res 59 (1999) 1146-1151
32. Guo C., Yu S., Davis A.T., Green J.E., and Ahmed K. A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells. J Biol Chem 276 (2001) 5992-5999
33. Hamacher R., Saur D., Fritsch R., Reichert M., Schmid R.M., and Schneider G. Casein kinase II inhibition induces apoptosis in pancreatic cancer cells. Oncol Rep 18 (2007) 695-701
34. He H., Tan M., Pamarthy D., Wang G., Ahmed K., and Sun Y. CK2-mediated phosphorylation of SAG at Thr 10 regulates its stability but not its E3 ligase activity. Mol Cell Biochem 295 (2007) 179-188
35. Izeradjene K., Douglas L., Delaney A., and Houghton J.A. Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines. Oncogene 24 (2005) 2050-2058
36. Kato T., Delhase M., Hoffmann A., and Karin M. CK2 is a C-terminal IκB kinase responsible for NF-κB activation during the UV response. Mol Cell 12 (2003) 829-839
37. Keller D.M., Zeng X., Wang Y., Zhang Q.H., Kapoor M., Shu H., et al. A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. Mol Cell 7 (2001) 283-292
38. Kelliher M.A., Seldin D.C., and Leder P. Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIα. EMBO J 15 (1996) 5160-5166
39. Krippner-Heidenreich A., Talanian R.V., Sekul R., Kraft R., Thole H., Ottleben H., et al. Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1. Biochem J 358 (2001) 705-715
40. Kyprianou N., Bruckheimer E.M., and Guo Y. Cell proliferation and apoptosis in prostate cancer: significance in disease progression and therapy. Histol Histopathol 15 (2000) 1211-1223
41. Laramas M., Pasquier D., Filhol O., Ringeisen F., Desxotes J.-L., and Cochet C. Nuclear localization of protein kinase CK2 catalytic subunit (CK2α) is associated with poor prognostic factors in human prostate cancer. Eur J Cancer 43 (2007) 928-934
42. Li P.F., Li J., Muller E.C., Otto A., Dietz R., and von Harsdorf R. Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC. Mol Cell 10 (2002) 247-258
43. Litchfield D.W. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369 (2003) 1-15
44. Loizou J.I., El-Khamisy S.F., Zlatanou A., Moore D.J., Chan D.W., Qin J., et al. The protein kinase CK2 facilitates repair of chromosomal DNA single stranded breaks. Cell 117 (2004) 17-28
45. Martel V., Filhol O., Nueda A., and Cochet C. Dynamic localization/association of protein kinase CK2 subunits in living cells: a role in its cellular regulation?. Ann NY Acad Sci 973 (2002) 272-277
46. Meggio F., and Pinna L.A. One-thousand-and-one substrates of protein kinase CK2?. FASEB J 17 (2003) 349-368
47. Mishra S., Pertz V., Zhang B., Kaur P., Shimada H., Groffen J., et al. Treatment of P190 Bcr/Abl lymphoblastic leukemia cells with inhibitors of the serine/threonine kinase CK2. Leukemia 21 (2007) 178-180
48. Okoumassoun L.E., Russo C., Denizeau F., Averill-Bates D., and Henderson J.E. Parathyroid hormone-related protein (PTHrP) inhibits mitochondrial-dependent apoptosis through CK2. J Cell Physiol 212 (2007) 591-599
49. Olsen B.B., Jessen V., Højrup P., Issinger O.G., and Boldyreff B. Protein kinase CK2 phosphorylates the Fas-associated factor FAF1 in vivo and influences its transport into the nucleus. FEBS Lett 546 (2003) 218-222
50. Olsen B.B., Petersen J., and Issinger O.-G. BID, an interaction partner of protein kinase CK2α. Biol Chem 387 (2006) 441-449
51. Olsten M.E.K., Weber J.E., and Litchfield D.W. CK2 interacting proteins: emerging paradigms for CK2 regulation?. Mol Cell Biochem 274 (2005) 115-124
52. Padmanabha R., Chen-Wu J.L.P., Hanna D.E., and Glover C.V.C. Isolation, sequencing, and disruption of the yeast CKA2 gene: casein kinase II is essential for viability in S. cerevisiae. Mol Cell Biol 10 (1990) 4089-4099
53. Pagano M., Poletto G., Di Maira G., Cozza G., Ruzzene M., Sarno S., et al. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. ChemBioChem 8 (2007) 129-139
54. Perea S.E., Reyes O., Puchades Y., Mendoza O., Vispo N.S., Torrens I., et al. Antitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2). Cancer Res 64 (2004) 7127-7129
55. Piazza F.A., Ruzzene M., Currieri C., Montini B., Bonanni L., Chioetto G., et al. Multiple myeloma cell survival relies on high activity of protein kinase CK2. Blood 108 (2006) 1698-1707
56. Pinna L.A. Protein kinase CK2: a challenge to canons. J Cell Sci 115 (2002) 3873-3878
57. Pyerin W., and Ackermann K. The genes encoding human protein kinase CK2 and their functional links. Progr Nucleic Acid Res Mol Biol 74 (2003) 239-273
58. Ravi R., and Bedi A. Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II. Cancer Res 62 (2002) 4180-4185
59. Romieu-Mourez R., Landesman-Bollag E., Seldin D.C., and Sonenshein G.E. Protein kinase CK2 promotes aberrant activation of nuclear factor-κB, transformed phenotype, and survival of breast cancer cells. Cancer Res 62 (2002) 6770-6778
60. Ruzzene M., Penzo D., and Pinna L.A. Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. Biochem J 364 (2002) 41-47
61. Salvi M., Sarno S., Marin O., Meggio F., Itarte E., and Pinna L.A. Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits. FEBS Lett 580 (2006) 3948-3952
62. Scaglioni P.P., Yung T.M., Cai L.F., Erdjument-Bromage H., Kaufman A.J., Singh B., et al. Cell 126 (2006) 269-283
63. Seeber S., Issinger O.-G., Holm T., Kristensen L.P., and Guerra B. Validation of protein kinase CK2 as oncological target. Apoptosis 10 (2005) 875-885
64. Shin S., Lee Y., Kim W., Ko H., Choi H., and Kim K. Caspase-2 primes cancer cells for TRAIL-mediated apoptosis by processing procaspase-8. EMBO J 24 (2005) 3532-3542
65. Slaton J.W., Sloper D.T., Unger G., Davis A., and Ahmed K. Induction of apoptosis by antisense CK2 in human prostate cancer xenograft model. Mol Cancer Res 2 (2004) 712-721
66. Tapia J.C., Torres V.A., Rodriguez D.A., Leyton L., and Quest A.F. Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. Proc Natl Acad Sci U S A 103 (2006) 15079-15084
67. Tawfic S., and Ahmed K. Association of casein kinase 2 (CK-2) with nuclear matrix: possible role in nuclear matrix protein phosphorylation. J Biol Chem 269 (1994) 7489-7493
68. Tawfic S., and Ahmed K. Growth stimulus-mediated differential translocation of casein kinase 2 to the nuclear matrix: evidence based on androgen action in the prostate. J Biol Chem 269 (1994) 24615-24620
69. Tawfic S., Davis A.T., Faust R.A., Gapany M., and Ahmed K. Association of protein kinase CK2 with nuclear matrix: influence of method of preparation of nuclear matrix. J Cell Biochem 64 (1997) 499-504
70. Tawfic S., Faust R.A., Gapany M., and Ahmed K. Nuclear matrix as an anchor for protein kinase CK2 nuclear signalling. J Cell Biochem 62 (1996) 165-171
71. Tawfic S., Yu S., Wang H., Faust R., Davis A., and Ahmed K. Protein kinase CK2 signal in neoplasia. Histol Histopathol 16 (2001) 573-582
72. Unger G.M., Davis A.T., Slaton J.W., and Ahmed K. Protein kinase CK2 as regulator of cell survival: implications for cancer therapy. Curr Cancer Drug Targets 4 (2004) 77-84
73. Vazquez F., Grossman S.R., Takahashi Y., Rokas M.V., Nakamura N., and Sellers W.R. Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. J Biol Chem 276 (2001) 48627-48630
74. Wang G., Ahmad K.A., and Ahmed K. Modulation of death receptor-mediated apoptosis by CK2. Mol Cell Biochem 274 (2005) 201-205
75. Wang G., Ahmad K.A., and Ahmed K. Role of CK2 in regulation of TRAIL induced apoptosis in prostate cancer cells. Cancer Res 66 (2006) 2242-2249
76. Wang G., Ahmad K.A., Unger G., Slaton J.W., and Ahmed K. CK2 signaling in androgen-dependent and - independent prostate cancer. J Cell Biochem 99 (2006) 382-391
77. Wang G., Unger G., Ahmad K.A., Slaton J.W., and Ahmed K. Downregulation of CK2 induces apoptosis in cancer cells - a potential approach to cancer therapy. Mol Cell Biochem 274 (2005) 77-84
78. Wang H., Davis A., Yu S., and Ahmed K. Response of cancer cells to molecular interruption of the CK2 signal. Mol Cell Biochem 227 (2001) 167-174
79. Wang H., Yu S., Davis A.T., and Ahmed K. Cell cycle dependent regulation of protein kinase CK2 signaling to the nuclear matrix. J Cell Biochem 88 (2003) 812-822
80. Xu X., Landesman-Bollag E., Channavajhala P.L., and Seldin D.C. Murine protein kinase CK2: gene and oncogene. Mol Cell Biochem 191 (1999) 65-74
81. Yamane K., and Kinsella T.J. CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation. Cancer Res 65 (2005) 4362-4367
82. Yenice S., Davis A.T., Goueli S.A., Akdas A., Limas E., and Ahmed K. Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate. Prostate 24 (1994) 11-16
83. Yu M., Yeh J., and Van Waes C. Protein kinase casein kinase 2 mediates inhibitor-κB kinase and aberrant nuclear factor-κB activation by serum factor(s) in head and neck squamous carcinoma cells. Cancer Res 66 (2006) 6722-6731
84. Yu S., Wang H., Davis A., and Ahmed K. Consequences of CK2 signaling to the nuclear matrix. Mol Cell Biochem 227 (2001) 67-71
85. Zhang P., Davis A.T., and Ahmed K. Mechanism of protein kinase CK2 association with nuclear matrix: role of disulfide bond formation. J Cell Biochem 69 (1998) 211-220
86. Zhang X., Jin T.-G., Yang H., DeWolf W.C., Khosravi-Far R., and Olumi A.F. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer. Cancer Res 64 (2004) 7086-7091