Tetrahydroxystilbene glucoside attenuates neuroinflammation through the inhibition of microglia activation

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2013, Pages

  Zhang, Feng ^a   Wang, Yan Ying ^a   Yang, Jun ^a   Lu, Yuan Fu ^a   Liu, Jie ^a   Shi, Jing Shan ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATES; CELL CULTURE; NEUROLOGY;

CARDIOPROTECTIVE EFFECT; NEUROLOGICAL DISEASE; NEUROLOGICAL DISORDERS; NEUROPROTECTIVE EFFECTS; PHARMACOLOGICAL PROPERTIES; POLYGONUM MULTIFLORUM; POTENTIAL THERAPIES; REACTIVE OXYGEN SPECIES;

FREE RADICALS;

2,3,5,4' ETRAHYDROXYSTILBENE 2 O BETA DEXTRO GLUCOSIDE; ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2,3,5,4' TETRAHYDROXYSTILBENE 2 O GLUCOSIDE; 2,3,5,4'-TETRAHYDROXYSTILBENE-2-O-GLUCOSIDE; GLUCOSIDE; LIPOPOLYSACCHARIDE; STILBENE DERIVATIVE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; FALLOPIA MULTIFLORA; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; INFLAMMATION; METABOLISM; NERVE CELL; PATHOLOGY; SIGNAL TRANSDUCTION;

POLYGONUM MULTIFLORUM;

ANIMALS; CELL LINE; ENZYME ACTIVATION; GLUCOSIDES; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; NADPH OXIDASE; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STILBENES;

EID: 84890082658     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/680545     Document Type: Article

References (36)

1. Hanisch U., Kettenmann H., Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nature Neuroscience 2007 10 11 1387 1394 2-s2.0-35548986304 10.1038/nn1997 (Pubitemid 350014685)
2. Nimmo A. J., Vink R., Recent patents in CNS drug discovery: the management of inflammation in the central nervous system. Recent Patents on CNS Drug Discovery 2009 4 2 86 95 2-s2.0-68849118781 10.2174/157488909788452997
3. Block M. L., Zecca L., Hong J., Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews Neuroscience 2007 8 1 57 69 2-s2.0-33845768784 10.1038/nrn2038 (Pubitemid 46011999)
4. Sugama S., Stress-induced microglial activation may facilitate the progression of neurodegenerative disorders. Medical Hypotheses 2009 73 6 1031 1034 2-s2.0-70449706451 10.1016/j.mehy.2009.02.047
5. Gao H. M., Liu B., Zhang W., Hong J. S., Novel anti-inflammatory therapy for Parkinson's disease. Trends in Pharmacological Sciences 2003 24 8 395 401 2-s2.0-0043162103 10.1016/S0165-6147(03)00176-7 (Pubitemid 36952555)
6. Block M. L., Hong J., Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Progress in Neurobiology 2005 76 2 77 98 2-s2.0-24144453087 10.1016/j.pneurobio.2005.06.004 (Pubitemid 41242883)
7. Gao H. M., Hong J. S., Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Trends in Immunology 2008 29 8 357 365 2-s2.0-47749126515 10.1016/j.it.2008.05.002
8. Chang M. J., Xiao J. H., Wang Y., Yan Y. L., Yang J., Wang J. L., 2, 3, 5, 4'-Tetrahydroxystilbene-2-O-beta-D-glucoside improves gastrointestinal motility disorders in STZ-induced diabetic mice. PLoS ONE 2012 7 12 e50291
9. Yao W., Fan W., Huang C., Zhong H., Chen X., Zhang W., Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats. Biomedicine and Pharmacotherapy 2013 67 2 140 145 10.1016/j.biopha.2012.10.007
10. Wang T., Gu J., Wu P., Wang F., Xiong Z., Yang Y., Wu W., Dong L., Chen J., Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radical Biology and Medicine 2009 47 3 229 240 2-s2.0-67349106386 10.1016/j.freeradbiomed.2009.02.027
11. (1-42)-injected rats and may be connected to synaptic changes in the hippocampus. Canadian Journal of Physiology and Pharmacology 2012 90 11 1446 1455
12. Zhang L., Yu S., Zhang R., Xing Y., Li Y., Li L., Tetrahydroxystilbene glucoside antagonizes age-related synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease. Restorative Neurology and Neuroscience 2013 31 1 41 52
13. Wang M. J., Huang H. Y., Chen W. F., Chang H. F., Kuo J. S., Glycogen synthase kinase-3 β inactivation inhibits tumor necrosis factor production in microglia by modulating nuclear factor kappaB and MLK3/JNK signaling cascades. Journal of Neuroinflammation 2010 7 99 116 2-s2.0-78650654039 10.1186/1742-2094-7-99
14. Choi Y., Lee M. K., Lim S. Y., Sung S. H., Kim Y. C., Inhibition of inducible NO synthase, cyclooxygenase-2 and interleukin-1 β by torilin is mediated by mitogen-activated protein kinases in microglial BV2 cells. British Journal of Pharmacology 2009 156 6 933 940 2-s2.0-67650642539 10.1111/j.1476-5381.2009.00022.x
15. Cao Q., Li P., Lu J., Dheen S. T., Kaur C., Ling E.-A., Nuclear factor-kappaB/p65 responds to changes in the notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the γ -secretase complex blocker DAPT. Journal of Neuroscience Research 2010 88 12 2701 2714 2-s2.0-77955496321 10.1002/jnr.22429
16. McGeer P. L., Itagaki S., Boyes B. E., McGeer E. G., Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988 38 8 1285 1291 2-s2.0-0023789193
17. Zhang W., Wang C., Li F., Zhu W., 2,3,4′5-tetrahydroxystilbene-2-O- β -D-glucoside suppresses matrix metalloproteinase expression and inflammation in atherosclerotic rats. Clinical and Experimental Pharmacology and Physiology 2008 35 3 310 316 2-s2.0-39149083101 10.1111/j.1440-1681.2007.04824. x (Pubitemid 351257879)
18. Zhang Y.-Z., Shen J.-F., Xu J.-Y., Xiao J.-H., Wang J.-L., Inhibitory effects of 2,3,5,4′-tetrahydroxystilbene-2-O- β -D- glucoside on experimental inflammation and cyclooxygenase 2 activity. Journal of Asian Natural Products Research 2007 9 4 355 363 2-s2.0-34447132909 10.1080/10286020600727772 (Pubitemid 47035933)
19. Kim W. G., Mohney R. P., Wilson B., Jeohn G. H., Liu B., Hong J. S., Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. Journal of Neuroscience 2000 20 16 6309 6316 2-s2.0-0034663061 (Pubitemid 30658427)
20. Gustafson S. J., Dunlap K. L., McGill C. M., Kuhn T. B., A nonpolar blueberry fraction blunts NADPH oxidase activation in neuronal cells exposed to tumor necrosis factor Oxidative Medicine and Cellular Longevity 2012 2012 12 2-s2.0-84859747274 10.1155/2012/768101 768101
21. Liu B., Hong J., Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. Journal of Pharmacology and Experimental Therapeutics 2003 304 1 1 7 2-s2.0-0037215645 10.1124/jpet.102.035048 (Pubitemid 36008905)
22. Uttara B., Singh A. V., Zamboni P., Mahajan R. T., Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Current Neuropharmacology 2009 7 1 65 74 2-s2.0-65949121134 10.2174/157015909787602823
23. Qin L., Liu Y., Wang T., Wei S., Block M. L., Wilson B., Liu B., Hong J., NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia. Journal of Biological Chemistry 2004 279 2 1415 1421 2-s2.0-0346463000 10.1074/jbc.M307657200 (Pubitemid 38082669)
24. Gao H. M., Jiang J., Wilson B., Zhang W., Hong J. S., Liu B., Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. Journal of Neurochemistry 2002 81 6 1285 1297 2-s2.0-0036316772 10.1046/j.1471-4159.2002. 00928.x (Pubitemid 34809262)
25. Hernandes M. S., Britto L. R., NADPH Oxidase and Neurodegeneration. Current Neuropharmacology 2012 10 4 321 327
26. Infanger D. W., Sharma R. V., Davisson R. L., NADPH oxidases of the brain: distribution, regulation, and function. Antioxidants and Redox Signaling 2006 8 9-10 1583 1596 2-s2.0-33744960694 10.1089/ars.2006.8.1583 (Pubitemid 44726333)
27. Gao H. M., Zhou H., Zhang F., Wilson B. C., Kam W., Hong J. S., HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. Journal of Neuroscience 2011 31 3 1081 1092 2-s2.0-78751502344 10.1523/JNEUROSCI.3732-10.2011
28. Tao L., Li X., Zhang L., Tian J., Li X., Sun X., Li X., Jiang L., Zhang X., Chen J., Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway. PLoS ONE 2011 6 10 2-s2.0-80053613745 10.1371/journal.pone.0026055 e26055
29. Hayden M. S., Ghosh S., Signaling to NF-kappaB. Genes and Development 2004 18 18 2195 2224 2-s2.0-4444376712 10.1101/gad.1228704 (Pubitemid 39209568)
30. Suh J., Rabson A. B., NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon? Journal of Cellular Biochemistry 2004 91 1 100 117 2-s2.0-3242798367 10.1002/jcb.10729
31. Hunot S., Brugg B., Ricard D., Michel P. P., Muriel M., Ruberg M., Faucheux B. A., Agid Y., Hirsch E. C., Nuclear translocation of NF-kappab is increased in dopaminergic neurons of patients with Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America 1997 94 14 7531 7536 2-s2.0-0030842085 10.1073/pnas.94.14.7531 (Pubitemid 27345350)
32. Ghosh A., Roy A., Liu X., Kordower J. H., Mufson E. J., Hartley D. M., Ghosh S., Mosley R. L., Gendelman H. E., Pahan K., Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 2007 104 47 18754 18759 2-s2.0-36749015082 10.1073/pnas.0704908104 (Pubitemid 350210769)
33. Xing B., Liu M., Bing G., Neuroprotection with pioglitazone against LPS insult on dopaminergic neurons may be associated with its inhibition of NF-kappaB and JNK activation and suppression of COX-2 activity. Journal of Neuroimmunology 2007 192 1-2 89 98 2-s2.0-36749097843 10.1016/j.jneuroim.2007. 09.029 (Pubitemid 350213119)
34. Ramanan S., Kooshki M., Zhao W., Hsu F., Robbins M. E., PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways. Free Radical Biology and Medicine 2008 45 12 1695 1704 2-s2.0-56349166510 10.1016/j.freeradbiomed.2008.09.002
35. Gao H. M., Zhou H., Hong J. S., NADPH oxidases: novel therapeutic targets for neurodegenerative diseases. Trends in Pharmacological Sciences 2012 33 6 295 303 2-s2.0-84859514311 10.1016/j.tips.2012.03.008
36. Pawate S., Shen Q., Fan F., Bhat N. R., Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma. Journal of Neuroscience Research 2004 77 4 540 551 2-s2.0-3442888512 10.1002/jnr.20180 (Pubitemid 39007006)