-
1
-
-
79955599940
-
Genetic and epigenetic signatures in human hepatocellular carcinoma: A systematic review
-
Nishida N, Goel A: Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review. Curr Genomics 2011; 12: 130-137.
-
(2011)
Curr Genomics
, vol.12
, pp. 130-137
-
-
Nishida, N.1
Goel, A.2
-
2
-
-
84867212593
-
Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections
-
Stauffer JK, Scarzello AJ, Jiang Q, Wiltrout RH: Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections. Hepatology 2012; 56: 1567-1574.
-
(2012)
Hepatology
, vol.56
, pp. 1567-1574
-
-
Stauffer, J.K.1
Scarzello, A.J.2
Jiang, Q.3
Wiltrout, R.H.4
-
3
-
-
84871842657
-
Epidemiology and surveillance of hepatocellular carcinoma
-
Kim DY, Han K: Epidemiology and surveillance of hepatocellular carcinoma. Liver Cancer 2012; 1: 2-14.
-
(2012)
Liver Cancer
, vol.1
, pp. 2-14
-
-
Kim, D.Y.1
Han, K.2
-
4
-
-
79956196320
-
Reactive oxygen species (ROS)-induced genetic and epigenetic alterations in human carcinogenesis
-
Ziech D, Franco R, Pappa A, Panayiotidis MI: Reactive oxygen species (ROS)-induced genetic and epigenetic alterations in human carcinogenesis. Mutat Res 2011; 711: 167-173.
-
(2011)
Mutat Res
, vol.711
, pp. 167-173
-
-
Ziech, D.1
Franco, R.2
Pappa, A.3
Panayiotidis, M.I.4
-
5
-
-
84858116393
-
Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis
-
Murata M, Thanan R, Ma N, Kawanishi S: Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. J Biomed Biotechnol 2012; 2012: 623019.
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 623019
-
-
Murata, M.1
Thanan, R.2
Ma, N.3
Kawanishi, S.4
-
6
-
-
0035175467
-
In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease
-
Kitada T, Seki S, Iwai S, Yamada T, Sakaguchi H, Wakasa K: In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease. J Hepatol 2001; 35: 613-618.
-
(2001)
J Hepatol
, vol.35
, pp. 613-618
-
-
Kitada, T.1
Seki, S.2
Iwai, S.3
Yamada, T.4
Sakaguchi, H.5
Wakasa, K.6
-
7
-
-
0035991444
-
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
-
Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, Wakasa K: In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J Hepatol 2002; 37: 56-62.
-
(2002)
J Hepatol
, vol.37
, pp. 56-62
-
-
Seki, S.1
Kitada, T.2
Yamada, T.3
Sakaguchi, H.4
Nakatani, K.5
Wakasa, K.6
-
8
-
-
84889884073
-
Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma
-
E-pub ahead of print
-
Tanaka S, Miyanishi K, Kobune M, Kawano Y, Hoki T, Kubo T, Hayashi T, Sato T, Sato Y, Takimoto R, Kato J: Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma. J Gastroenterol 2013, E-pub ahead of print.
-
(2013)
J Gastroenterol
-
-
Tanaka, S.1
Miyanishi, K.2
Kobune, M.3
Kawano, Y.4
Hoki, T.5
Kubo, T.6
Hayashi, T.7
Sato, T.8
Sato, Y.9
Takimoto, R.10
Kato, J.11
-
9
-
-
78549267771
-
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine
-
Beard WA, Batra VK, Wilson SH: DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine. Mutat Res 2010; 703: 18-23.
-
(2010)
Mutat Res
, vol.703
, pp. 18-23
-
-
Beard, W.A.1
Batra, V.K.2
Wilson, S.H.3
-
10
-
-
85027927831
-
High-resolution characterization of a hepatocellular carcinoma genome
-
Totoki Y, Tatsuno K, Yamamoto S, Arai Y, Hosoda F, Ishikawa S, Tsutsumi S, Sonoda K, Totsuka H, Shirakihara T, Sakamoto H, Wang L, Ojima H, Shimada K, Kosuge T, Okusaka T, Kato K, Kusuda J, Yoshida T, Aburatani H, Shibata T: High-resolution characterization of a hepatocellular carcinoma genome. Nat Genet 2011; 43: 464-469.
-
(2011)
Nat Genet
, vol.43
, pp. 464-469
-
-
Totoki, Y.1
Tatsuno, K.2
Yamamoto, S.3
Arai, Y.4
Hosoda, F.5
Ishikawa, S.6
Tsutsumi, S.7
Sonoda, K.8
Totsuka, H.9
Shirakihara, T.10
Sakamoto, H.11
Wang, L.12
Ojima, H.13
Shimada, K.14
Kosuge, T.15
Okusaka, T.16
Kato, K.17
Kusuda, J.18
Yoshida, T.19
Aburatani, H.20
Shibata, T.21
more..
-
11
-
-
0028567172
-
Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma
-
Hagen TM, Huang S, Curnutte J, Fowler P, Martinez V, Wehr CM, Ames BN, Chisari FV: Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc Natl Acad Sci USA 1994; 91: 12808-12812.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12808-12812
-
-
Hagen, T.M.1
Huang, S.2
Curnutte, J.3
Fowler, P.4
Martinez, V.5
Wehr, C.M.6
Ames, B.N.7
Chisari, F.V.8
-
12
-
-
0141849146
-
Reactive oxygen species modulates the intracellular level of HBx viral oncoprotein
-
Wang JH, Yun C, Kim S, Lee JH, Yoon G, Lee MO, Cho H: Reactive oxygen species modulates the intracellular level of HBx viral oncoprotein. Biochem Biophys Res Commun 2003; 310: 32-39.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 32-39
-
-
Wang, J.H.1
Yun, C.2
Kim, S.3
Lee, J.H.4
Yoon, G.5
Lee, M.O.6
Cho, H.7
-
13
-
-
77953578573
-
Viral-induced human carcinogenesis: An oxidative stress perspective
-
Georgakilas AG, Mosley WG, Georgakila S, Ziech D, Panayiotidis MI: Viral-induced human carcinogenesis: an oxidative stress perspective. Mol Biosyst 2010; 6: 1162-1172.
-
(2010)
Mol Biosyst
, vol.6
, pp. 1162-1172
-
-
Georgakilas, A.G.1
Mosley, W.G.2
Georgakila, S.3
Ziech, D.4
Panayiotidis, M.I.5
-
14
-
-
77649207541
-
Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1
-
Pal S, Polyak SJ, Bano N, Qiu WC, Carithers RL, Shuhart M, Gretch DR, Das A: Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1. J Gastroenterol Hepatol 2010; 25: 627-634.
-
(2010)
J Gastroenterol Hepatol
, vol.25
, pp. 627-634
-
-
Pal, S.1
Polyak, S.J.2
Bano, N.3
Qiu, W.C.4
Carithers, R.L.5
Shuhart, M.6
Gretch, D.R.7
Das, A.8
-
15
-
-
34250160595
-
Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma
-
Maki A, Kono H, Gupta M, Asakawa M, Suzuki T, Matsuda M, Fujii H, Rusyn I: Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Ann Surg Oncol 2007; 14: 1182-1190.
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 1182-1190
-
-
Maki, A.1
Kono, H.2
Gupta, M.3
Asakawa, M.4
Suzuki, T.5
Matsuda, M.6
Fujii, H.7
Rusyn, I.8
-
16
-
-
0037333913
-
Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2α kinase perk
-
Pavio N, Romano PR, Graczyk TM, Feinstone SM, Taylor DR: Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2α kinase perk. J Virol 2003; 77: 3578-3585.
-
(2003)
J Virol
, vol.77
, pp. 3578-3585
-
-
Pavio, N.1
Romano, P.R.2
Graczyk, T.M.3
Feinstone, S.M.4
Taylor, D.R.5
-
17
-
-
16244405250
-
Hepatitis C virus, ER stress, and oxidative stress
-
Tardif KD, Waris G, Siddiqui A: Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol 2005; 13: 159-163.
-
(2005)
Trends Microbiol
, vol.13
, pp. 159-163
-
-
Tardif, K.D.1
Waris, G.2
Siddiqui, A.3
-
18
-
-
33947575032
-
Does oxidative stress participate in the development of hepatocellular carcinoma?
-
Sasaki Y: Does oxidative stress participate in the development of hepatocellular carcinoma? J Gastroenterol 2006; 41: 1135-1148.
-
(2006)
J Gastroenterol
, vol.41
, pp. 1135-1148
-
-
Sasaki, Y.1
-
19
-
-
0036556684
-
The mammalian endoplasmic reticulum as a sensor for cellular stress
-
Ma Y, Hendershot LM: The mammalian endoplasmic reticulum as a sensor for cellular stress. Cell Stress Chaperones 2002; 7: 222-229.
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 222-229
-
-
Ma, Y.1
Hendershot, L.M.2
-
20
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Ishibashi K, Matsuura Y, Kimura S, Miyamura T, Koike K: The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998; 4: 1065-1067.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
Yotsuyanagi, H.4
Tsutsumi, T.5
Ishibashi, K.6
Matsuura, Y.7
Kimura, S.8
Miyamura, T.9
Koike, K.10
-
21
-
-
27844604269
-
Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
-
Korenaga M, Wang T, Li Y, Showalter LA, Chan T, Sun J, Weinman SA: Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem 2005; 280: 37481-37488.
-
(2005)
J Biol Chem
, vol.280
, pp. 37481-37488
-
-
Korenaga, M.1
Wang, T.2
Li, Y.3
Showalter, L.A.4
Chan, T.5
Sun, J.6
Weinman, S.A.7
-
22
-
-
0035859871
-
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB
-
Gong G, Waris G, Tanveer R, Siddiqui A: Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB. Proc Natl Acad Sci USA 2001; 98: 9599-9604.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9599-9604
-
-
Gong, G.1
Waris, G.2
Tanveer, R.3
Siddiqui, A.4
-
23
-
-
0033535442
-
Oxidative DNA damage mediated by copper(II), iron(II) and nickel(II) fenton reactions: Evidence for sitespecific mechanisms in the formation of double-strand breaks, 8-hydroxydeoxyguanosine and putative intrastrand cross-links
-
Lloyd DR, Phillips DH: Oxidative DNA damage mediated by copper(II), iron(II) and nickel(II) fenton reactions: evidence for sitespecific mechanisms in the formation of double-strand breaks, 8-hydroxydeoxyguanosine and putative intrastrand cross-links. Mutat Res 1999; 424: 23-36.
-
(1999)
Mutat Res
, vol.424
, pp. 23-36
-
-
Lloyd, D.R.1
Phillips, D.H.2
-
24
-
-
33744512454
-
Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein
-
Furutani T, Hino K, Okuda M, Gondo T, Nishina S, Kitase A, Korenaga M, Xiao SY, Weinman SA, Lemon SM, Sakaida I, Okita K: Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein. Gastroenterology 2006; 130: 2087-2098.
-
(2006)
Gastroenterology
, vol.130
, pp. 2087-2098
-
-
Furutani, T.1
Hino, K.2
Okuda, M.3
Gondo, T.4
Nishina, S.5
Kitase, A.6
Korenaga, M.7
Xiao, S.Y.8
Weinman, S.A.9
Lemon, S.M.10
Sakaida, I.11
Okita, K.12
-
25
-
-
3242887231
-
A significant reduction in serum alanine aminotransferase levels after 3-month iron reduction therapy for chronic hepatitis C: A multicenter, prospective, randomized, controlled trial in Japan
-
Yano M, Hayashi H, Yoshioka K, Kohgo Y, Saito H, Niitsu Y, Kato J, Iino S, Yotsuyanagi H, Kobayashi Y, Kawamura K, Kakumu S, Kaito M, Ikoma J, Wakusawa S, Okanoue T, Sumida Y, Kimura F, Kajiwara E, Sata M, Ogata K: A significant reduction in serum alanine aminotransferase levels after 3-month iron reduction therapy for chronic hepatitis C: a multicenter, prospective, randomized, controlled trial in Japan. J Gastroenterol 2004; 39: 570-574.
-
(2004)
J Gastroenterol
, vol.39
, pp. 570-574
-
-
Yano, M.1
Hayashi, H.2
Yoshioka, K.3
Kohgo, Y.4
Saito, H.5
Niitsu, Y.6
Kato, J.7
Iino, S.8
Yotsuyanagi, H.9
Kobayashi, Y.10
Kawamura, K.11
Kakumu, S.12
Kaito, M.13
Ikoma, J.14
Wakusawa, S.15
Okanoue, T.16
Sumida, Y.17
Kimura, F.18
Kajiwara, E.19
Sata, M.20
Ogata, K.21
more..
-
26
-
-
0035893552
-
Normalization of elevated hepatic 8-hydroxy-2. ′-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet
-
Kato J, Kobune M, Nakamura T, Kuroiwa G, Takada K, Takimoto R, Sato Y, Fujikawa K, Takahashi M, Takayama T, Ikeda T, Niitsu Y: Normalization of elevated hepatic 8-hydroxy-2. ′-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet. Cancer Res 2001; 61: 8697-8702.
-
(2001)
Cancer Res
, vol.61
, pp. 8697-8702
-
-
Kato, J.1
Kobune, M.2
Nakamura, T.3
Kuroiwa, G.4
Takada, K.5
Takimoto, R.6
Sato, Y.7
Fujikawa, K.8
Takahashi, M.9
Takayama, T.10
Ikeda, T.11
Niitsu, Y.12
-
27
-
-
33746330393
-
Effects of ethanol and acetaldehyde on reactive oxygen species production in rat hepatic stellate cells
-
Novitskiy G, Traore K, Wang L, Trush MA, Mezey E: Effects of ethanol and acetaldehyde on reactive oxygen species production in rat hepatic stellate cells. Alcohol Clin Exp Res 2006; 30: 1429-1435.
-
(2006)
Alcohol Clin Exp Res
, vol.30
, pp. 1429-1435
-
-
Novitskiy, G.1
Traore, K.2
Wang, L.3
Trush, M.A.4
Mezey, E.5
-
28
-
-
84863770814
-
Cancer genetics and epigenetics: Two sides of the same coin?
-
You JS, Jones PA: Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell 2012; 22: 9-20.
-
(2012)
Cancer Cell
, vol.22
, pp. 9-20
-
-
You, J.S.1
Jones, P.A.2
-
29
-
-
57249103576
-
Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: Methylation of the E-cadherin promoter
-
Lim SO, Gu JM, Kim MS, Kim HS, Park YN, Park CK, Cho JW, Park YM, Jung G: Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology 2008; 135: 2128-2140.
-
(2008)
Gastroenterology
, vol.135
, pp. 2128-2140
-
-
Lim, S.O.1
Gu, J.M.2
Kim, M.S.3
Kim, H.S.4
Park, Y.N.5
Park, C.K.6
Cho, J.W.7
Park, Y.M.8
Jung, G.9
-
30
-
-
84860269756
-
Epigenetic changes induced by oxidative stress in colorectal cancer cells: Methylation of tumor suppressor RUNX3
-
Kang KA, Zhang R, Kim GY, Bae SC, Hyun JW: Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3. Tumour Biol 2012; 33: 403-412.
-
(2012)
Tumour Biol
, vol.33
, pp. 403-412
-
-
Kang, K.A.1
Zhang, R.2
Kim, G.Y.3
Bae, S.C.4
Hyun, J.W.5
-
31
-
-
81255162523
-
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG islands
-
O'Hagan HM, Wang W, Sen S, Destefano Shields C, Lee SS, Zhang YW, Clements EG, Cai Y, Van Neste L, Easwaran H, Casero RA, Sears CL, Baylin SB: Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG islands. Cancer Cell 2011; 20: 606-619.
-
(2011)
Cancer Cell
, vol.20
, pp. 606-619
-
-
O'Hagan, H.M.1
Wang, W.2
Sen, S.3
Destefano Shields, C.4
Lee, S.S.5
Zhang, Y.W.6
Clements, E.G.7
Cai, Y.8
Van Neste, L.9
Easwaran, H.10
Casero, R.A.11
Sears, C.L.12
Baylin, S.B.13
-
32
-
-
32944459562
-
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
-
Maekita T, Nakazawa K, Mihara M, Nakajima T, Yanaoka K, Iguchi M, Arii K, Kaneda A, Tsukamoto T, Tatematsu M, Tamura G, Saito D, Sugimura T, Ichinose M, Ushijima T: High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006; 12: 989-995.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 989-995
-
-
Maekita, T.1
Nakazawa, K.2
Mihara, M.3
Nakajima, T.4
Yanaoka, K.5
Iguchi, M.6
Arii, K.7
Kaneda, A.8
Tsukamoto, T.9
Tatematsu, M.10
Tamura, G.11
Saito, D.12
Sugimura, T.13
Ichinose, M.14
Ushijima, T.15
-
33
-
-
60149102748
-
Mouse models for the study of colon carcinogenesis
-
Rosenberg DW, Giardina C, Tanaka T: Mouse models for the study of colon carcinogenesis. Carcinogenesis 2009; 30: 183-196.
-
(2009)
Carcinogenesis
, vol.30
, pp. 183-196
-
-
Rosenberg, D.W.1
Giardina, C.2
Tanaka, T.3
-
34
-
-
84865510127
-
Inflammation-associated cancer development in digestive organs: Mechanisms and roles for genetic and epigenetic modulation
-
Chiba T, Marusawa H, Ushijima T: Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation. Gastroenterology 2012; 143: 550-563.
-
(2012)
Gastroenterology
, vol.143
, pp. 550-563
-
-
Chiba, T.1
Marusawa, H.2
Ushijima, T.3
-
35
-
-
0033404952
-
Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production
-
Hmadcha A, Bedoya FJ, Sobrino F, Pintado E: Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production. J Exp Med 1999; 190: 1595-1604.
-
(1999)
J Exp Med
, vol.190
, pp. 1595-1604
-
-
Hmadcha, A.1
Bedoya, F.J.2
Sobrino, F.3
Pintado, E.4
-
36
-
-
0035955640
-
Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells
-
Hodge DR, Xiao W, Clausen PA, Heidecker G, Szyf M, Farrar WL: Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells. J Biol Chem 2001; 276: 39508-39511.
-
(2001)
J Biol Chem
, vol.276
, pp. 39508-39511
-
-
Hodge, D.R.1
Xiao, W.2
Clausen, P.A.3
Heidecker, G.4
Szyf, M.5
Farrar, W.L.6
-
37
-
-
77950600443
-
Microrna-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes
-
Braconi C, Huang N, Patel T: Microrna-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes. Hepatology 2010; 51: 881-890.
-
(2010)
Hepatology
, vol.51
, pp. 881-890
-
-
Braconi, C.1
Huang, N.2
Patel, T.3
-
38
-
-
84856748026
-
Prostaglandin E2 promotes intestinal tumor growth via DNA methylation
-
Xia D, Wang D, Kim SH, Katoh H, DuBois RN: Prostaglandin E2 promotes intestinal tumor growth via DNA methylation. Nature Med 2012; 18: 224-226.
-
(2012)
Nature Med
, vol.18
, pp. 224-226
-
-
Xia, D.1
Wang, D.2
Kim, S.H.3
Katoh, H.4
Dubois, R.N.5
-
39
-
-
79959743101
-
Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells
-
Gasche JA, Hoffmann J, Boland CR, Goel A: Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells. Int J Cancer 2011; 129: 1053-1063.
-
(2011)
Int J Cancer
, vol.129
, pp. 1053-1063
-
-
Gasche, J.A.1
Hoffmann, J.2
Boland, C.R.3
Goel, A.4
-
40
-
-
6944250441
-
Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line
-
To KF, Chan MW, Leung WK, Ng EK, Yu J, Bai AH, Lo AW, Chu SH, Tong JH, Lo KW, Sung JJ, Chan FK: Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line. Br J Cancer 2004; 91: 1335-1341.
-
(2004)
Br J Cancer
, vol.91
, pp. 1335-1341
-
-
To, K.F.1
Chan, M.W.2
Leung, W.K.3
Ng, E.K.4
Yu, J.5
Bai, A.H.6
Lo, A.W.7
Chu, S.H.8
Tong, J.H.9
Lo, K.W.10
Sung, J.J.11
Chan, F.K.12
-
41
-
-
33846200831
-
Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing
-
Isomoto H, Mott JL, Kobayashi S, Werneburg NW, Bronk SF, Haan S, Gores GJ: Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology 2007; 132: 384-396.
-
(2007)
Gastroenterology
, vol.132
, pp. 384-396
-
-
Isomoto, H.1
Mott, J.L.2
Kobayashi, S.3
Werneburg, N.W.4
Bronk, S.F.5
Haan, S.6
Gores, G.J.7
-
42
-
-
33645784375
-
Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation
-
Wong NC, Wong LH, Quach JM, Canham P, Craig JM, Song JZ, Clark SJ, Choo KH: Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation. PLoS Genet 2006; 2:e17.
-
(2006)
PLoS Genet
, vol.2
-
-
Wong, N.C.1
Wong, L.H.2
Quach, J.M.3
Canham, P.4
Craig, J.M.5
Song, J.Z.6
Clark, S.J.7
Choo, K.H.8
-
43
-
-
56649115881
-
Epigenetic regulation of telomeres in human cancer
-
Vera E, Canela A, Fraga MF, Esteller M, Blasco MA: Epigenetic regulation of telomeres in human cancer. Oncogene 2008; 27: 6817-6833.
-
(2008)
Oncogene
, vol.27
, pp. 6817-6833
-
-
Vera, E.1
Canela, A.2
Fraga, M.F.3
Esteller, M.4
Blasco, M.A.5
-
44
-
-
38049164130
-
Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
-
Howard G, Eiges R, Gaudet F, Jaenisch R, Eden A: Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene 2008; 27: 404-408.
-
(2008)
Oncogene
, vol.27
, pp. 404-408
-
-
Howard, G.1
Eiges, R.2
Gaudet, F.3
Jaenisch, R.4
Eden, A.5
-
45
-
-
0026579875
-
Methyl groups in carcinogenesis: Effects on DNA methylation and gene expression
-
Wainfan E, Poirier LA: Methyl groups in carcinogenesis: effects on DNA methylation and gene expression. Cancer Res 1992; 52: 2071s-2077s.
-
(1992)
Cancer Res
, vol.52
-
-
Wainfan, E.1
Poirier, L.A.2
-
46
-
-
80052234430
-
Definition of the landscape of promoter DNA hypomethylation in liver cancer
-
Stefanska B, Huang J, Bhattacharyya B, Suderman M, Hallett M, Han ZG, Szyf M: Definition of the landscape of promoter DNA hypomethylation in liver cancer. Cancer Res 2011; 71: 5891-5903.
-
(2011)
Cancer Res
, vol.71
, pp. 5891-5903
-
-
Stefanska, B.1
Huang, J.2
Bhattacharyya, B.3
Suderman, M.4
Hallett, M.5
Han, Z.G.6
Szyf, M.7
-
47
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wessels A, Soprano D, Abramowitz LK, Bartolomei MS, Rambow F, Bassi MR, Bruno T, Fanciulli M, Renner C, Klein-Szanto AJ, Matsumoto Y, Kobi D, Davidson I, Alberti C, Larue L, Bellacosa A: Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011; 146: 67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
Abramowitz, L.K.11
Bartolomei, M.S.12
Rambow, F.13
Bassi, M.R.14
Bruno, T.15
Fanciulli, M.16
Renner, C.17
Klein-Szanto, A.J.18
Matsumoto, Y.19
Kobi, D.20
Davidson, I.21
Alberti, C.22
Larue, L.23
Bellacosa, A.24
more..
-
48
-
-
84857131585
-
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
-
Kato L, Begum NA, Burroughs AM, Doi T, Kawai J, Daub CO, Kawaguchi T, Matsuda F, Hayashizaki Y, Honjo T: Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes. Proc Natl Acad Sci USA 2012; 109: 2479-2484.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2479-2484
-
-
Kato, L.1
Begum, N.A.2
Burroughs, A.M.3
Doi, T.4
Kawai, J.5
Daub, C.O.6
Kawaguchi, T.7
Matsuda, F.8
Hayashizaki, Y.9
Honjo, T.10
-
49
-
-
66849119061
-
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
-
Ma DK, Guo JU, Ming GL, Song H: DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle 2009; 8: 1526-1531.
-
(2009)
Cell Cycle
, vol.8
, pp. 1526-1531
-
-
Ma, D.K.1
Guo, J.U.2
Ming, G.L.3
Song, H.4
-
50
-
-
56149125340
-
Hypoxia, angiogenesis, and lung cancer
-
Goudar RK, Vlahovic G: Hypoxia, angiogenesis, and lung cancer. Curr Oncol Rep 2008; 10: 277-282.
-
(2008)
Curr Oncol Rep
, vol.10
, pp. 277-282
-
-
Goudar, R.K.1
Vlahovic, G.2
-
51
-
-
72849111790
-
Oxidative stress induced lung cancer and COPD: Opportunities for epigenetic therapy
-
Lawless MW, O'Byrne KJ, Gray SG: Oxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy. J Cell Mol Med 2009; 13: 2800-2821.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2800-2821
-
-
Lawless, M.W.1
O'Byrne, K.J.2
Gray, S.G.3
-
52
-
-
58049125816
-
Relationship between oxidative stress and HIF-1α mRNA during sustained hypoxia in humans
-
Pialoux V, Mounier R, Brown AD, Steinback CD, Rawling JM, Poulin MJ: Relationship between oxidative stress and HIF-1α mRNA during sustained hypoxia in humans. Free Radic Biol Med 2009; 46: 321-326.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 321-326
-
-
Pialoux, V.1
Mounier, R.2
Brown, A.D.3
Steinback, C.D.4
Rawling, J.M.5
Poulin, M.J.6
-
53
-
-
0033986948
-
Redoxregulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1α
-
Carrero P, Okamoto K, Coumailleau P, O'Brien S, Tanaka H, Poellinger L: Redoxregulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1α. Mol Cell Biol 2000; 20: 402-415.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 402-415
-
-
Carrero, P.1
Okamoto, K.2
Coumailleau, P.3
O'Brien, S.4
Tanaka, H.5
Poellinger, L.6
-
54
-
-
0037064141
-
Functional analysis of hypoxia-inducible factor-1α-mediated transactivation: Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB binding protein
-
Ruas JL, Poellinger L, Pereira T: Functional analysis of hypoxia-inducible factor-1α-mediated transactivation: identification of amino acid residues critical for transcriptional activation and/or interaction with CREB binding protein. J Biol Chem 2002; 277: 38723-38730.
-
(2002)
J Biol Chem
, vol.277
, pp. 38723-38730
-
-
Ruas, J.L.1
Poellinger, L.2
Pereira, T.3
-
55
-
-
53249088036
-
PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
-
Xenaki G, Ontikatze T, Rajendran R, Stratford IJ, Dive C, Krstic-Demonacos M, Demonacos C: PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia. Oncogene 2008; 27: 5785-5796.
-
(2008)
Oncogene
, vol.27
, pp. 5785-5796
-
-
Xenaki, G.1
Ontikatze, T.2
Rajendran, R.3
Stratford, I.J.4
Dive, C.5
Krstic-Demonacos, M.6
Demonacos, C.7
-
56
-
-
4043112183
-
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
-
Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC: Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004; 32: 4100-4108.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4100-4108
-
-
Valinluck, V.1
Tsai, H.H.2
Rogstad, D.K.3
Burdzy, A.4
Bird, A.5
Sowers, L.C.6
-
57
-
-
84866740172
-
Environmental epigenetics: Prospects for studying epigenetic mediation of exposure-response relationships
-
Cortessis VK, Thomas DC, Levine AJ, Breton CV, Mack TM, Siegmund KD, Haile RW, Laird PW: Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Human Genet 2012; 131: 1565-1589.
-
(2012)
Human Genet
, vol.131
, pp. 1565-1589
-
-
Cortessis, V.K.1
Thomas, D.C.2
Levine, A.J.3
Breton, C.V.4
MacK, T.M.5
Siegmund, K.D.6
Haile, R.W.7
Laird, P.W.8
-
59
-
-
0029001483
-
DNA adduct 8-hydroxyl-2 ′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase
-
Turk PW, Laayoun A, Smith SS, Weitzman SA: DNA adduct 8-hydroxyl-2 ′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase. Carcinogenesis 1995; 16: 1253-1255.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1253-1255
-
-
Turk, P.W.1
Laayoun, A.2
Smith, S.S.3
Weitzman, S.A.4
-
60
-
-
79956212196
-
Oxidative stress and DNA methylation in prostate cancer
-
Donkena KV, Young CY, Tindall DJ: Oxidative stress and DNA methylation in prostate cancer. Obstet Gynecol Int 2010; 2010: 302051.
-
(2010)
Obstet Gynecol Int
, vol.2010
, pp. 302051
-
-
Donkena, K.V.1
Young, C.Y.2
Tindall, D.J.3
-
61
-
-
77954679759
-
Superoxide dismutase l knockdown induces oxidative stress and DNA methylation loss in the prostate
-
Bhusari SS, Dobosy JR, Fu V, Almassi N, Oberley T, Jarrard DF: Superoxide dismutase l knockdown induces oxidative stress and DNA methylation loss in the prostate. Epigenetics 2010; 5: 402-409.
-
(2010)
Epigenetics
, vol.5
, pp. 402-409
-
-
Bhusari, S.S.1
Dobosy, J.R.2
Fu, V.3
Almassi, N.4
Oberley, T.5
Jarrard, D.F.6
-
62
-
-
84873323910
-
Wilson's disease: Changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease
-
Medici V, Shibata NM, Kharbanda KK, La-Salle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Torok NJ, Jiang JX, Havel PJ, Lonnerdal B, Kim K, Halsted CH: Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatology 2013; 57: 555-565.
-
(2013)
Hepatology
, vol.57
, pp. 555-565
-
-
Medici, V.1
Shibata, N.M.2
Kharbanda, K.K.3
La-Salle, J.M.4
Woods, R.5
Liu, S.6
Engelberg, J.A.7
Devaraj, S.8
Torok, N.J.9
Jiang, J.X.10
Havel, P.J.11
Lonnerdal, B.12
Kim, K.13
Halsted, C.H.14
-
63
-
-
84866493708
-
Long interspersed nuclear element-1 hypomethylation and oxidative stress: Correlation and bladder cancer diagnostic potential
-
Patchsung M, Boonla C, Amnattrakul P, Dissayabutra T, Mutirangura A, Tosukhowong P: Long interspersed nuclear element-1 hypomethylation and oxidative stress: correlation and bladder cancer diagnostic potential. PLoS One 2012; 7:e37009.
-
(2012)
PLoS One
, vol.7
-
-
Patchsung, M.1
Boonla, C.2
Amnattrakul, P.3
Dissayabutra, T.4
Mutirangura, A.5
Tosukhowong, P.6
-
64
-
-
34548140496
-
An epigenetic perspective on the free radical theory of development
-
Hitchler MJ, Domann FE: An epigenetic perspective on the free radical theory of development. Free Radic Biol Med 2007; 43: 1023-1036.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 1023-1036
-
-
Hitchler, M.J.1
Domann, F.E.2
|