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Volumn 310, Issue 1, 2003, Pages 32-39

Reactive oxygen species modulates the intracellular level of HBx viral oncoprotein

Author keywords

Adriamycin; Antioxidants; Gene expression; HBV; HBx; ROS

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CISPLATIN; DOXORUBICIN; FLUOROURACIL; HEPATITIS B VIRUS X PROTEIN; HYDROGEN PEROXIDE; ONCOPROTEIN; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 0141849146     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.08.113     Document Type: Article
Times cited : (26)

References (44)
  • 1
    • 0026701093 scopus 로고
    • Hepatitis B viruses and hepatocellular carcinoma
    • Buendia M.A. Hepatitis B viruses and hepatocellular carcinoma. Adv. Cancer Res. 59:1992;167-226.
    • (1992) Adv. Cancer Res. , vol.59 , pp. 167-226
    • Buendia, M.A.1
  • 3
    • 0034954277 scopus 로고    scopus 로고
    • X protein of hepatitis B virus modulates cytokine and growth factor related transduction pathways during the course of viral infection and hepatocarcinogenesis
    • Diago J., Garces R., Richardson C.D. X protein of hepatitis B virus modulates cytokine and growth factor related transduction pathways during the course of viral infection and hepatocarcinogenesis. Cytokines Growth Factor Rev. 12:2001;189-205.
    • (2001) Cytokines Growth Factor Rev. , vol.12 , pp. 189-205
    • Diago, J.1    Garces, R.2    Richardson, C.D.3
  • 5
    • 0029147911 scopus 로고
    • The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors
    • Doria M., Klein N., Lucito R., Schneider R.J. The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. EMBO J. 14:1995;4747-4757.
    • (1995) EMBO J. , vol.14 , pp. 4747-4757
    • Doria, M.1    Klein, N.2    Lucito, R.3    Schneider, R.J.4
  • 6
    • 0030764344 scopus 로고    scopus 로고
    • Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras
    • Klein N.P., Schneider R.J. Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras. Mol. Cell. Biol. 17:1997;6427-6436.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6427-6436
    • Klein, N.P.1    Schneider, R.J.2
  • 7
    • 0034682769 scopus 로고    scopus 로고
    • Hepatitis B virus X protein inhibits transforming growth factor-beta-induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway
    • Shih W.L., Kuo M.L., Chuang S.E., Cheng A.L., Doong S.L. Hepatitis B virus X protein inhibits transforming growth factor-beta-induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway. J. Biol. Chem. 275:2000;25858-25864.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25858-25864
    • Shih, W.L.1    Kuo, M.L.2    Chuang, S.E.3    Cheng, A.L.4    Doong, S.L.5
  • 8
    • 0032538547 scopus 로고    scopus 로고
    • The hepatitis B virus X protein is a co-activator of activated transcription that modulates the transcription machinery and distal binding activators
    • Lin Y., Tang H., Nomura T., Dorjsuren D., Hayashi N., Wei W., Ohta T., Roeder R., Murakami S. The hepatitis B virus X protein is a co-activator of activated transcription that modulates the transcription machinery and distal binding activators. J. Biol. Chem. 273:1998;27097-27103.
    • (1998) J. Biol. Chem. , vol.273 , pp. 27097-27103
    • Lin, Y.1    Tang, H.2    Nomura, T.3    Dorjsuren, D.4    Hayashi, N.5    Wei, W.6    Ohta, T.7    Roeder, R.8    Murakami, S.9
  • 9
    • 0030989802 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5
    • Lin Y., Nomura T., Cheong J., Dorjsuren D., Iida K., Murakami S. Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5. J. Biol. Chem. 272:1997;7132-7139.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7132-7139
    • Lin, Y.1    Nomura, T.2    Cheong, J.3    Dorjsuren, D.4    Iida, K.5    Murakami, S.6
  • 10
    • 0035804226 scopus 로고    scopus 로고
    • Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis
    • Kim Y.C., Song K.S., Yoon G., Nam M.J., Ryu W.S. Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis. Oncogene. 20:2001;16-23.
    • (2001) Oncogene , vol.20 , pp. 16-23
    • Kim, Y.C.1    Song, K.S.2    Yoon, G.3    Nam, M.J.4    Ryu, W.S.5
  • 12
    • 0028230728 scopus 로고
    • High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice
    • Koike K., Moriya K., Iino S., Yotsuyanagi H., Endo Y., Miyamura T., Kurokawa K. High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice. Hepatology. 19:1994;810-819.
    • (1994) Hepatology , vol.19 , pp. 810-819
    • Koike, K.1    Moriya, K.2    Iino, S.3    Yotsuyanagi, H.4    Endo, Y.5    Miyamura, T.6    Kurokawa, K.7
  • 14
    • 0035723367 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X (HBx) protein is closely correlated with the high periportal inflammatory activity of liver diseases
    • Jin Y.M., Yun C., Park C., Wang H.J., Cho H. Expression of hepatitis B virus X (HBx) protein is closely correlated with the high periportal inflammatory activity of liver diseases. J. Viral Hepatitis. 8:2001;330-332.
    • (2001) J. Viral Hepatitis , vol.8 , pp. 330-332
    • Jin, Y.M.1    Yun, C.2    Park, C.3    Wang, H.J.4    Cho, H.5
  • 15
    • 0031898616 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinoma
    • Su Q., Schroder C.H., Hofmann W.J., Otto G., Pichimayr R., Bannasch P. Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinoma. Hepatology. 27:1998;1109-1120.
    • (1998) Hepatology , vol.27 , pp. 1109-1120
    • Su, Q.1    Schroder, C.H.2    Hofmann, W.J.3    Otto, G.4    Pichimayr, R.5    Bannasch, P.6
  • 16
    • 0024538208 scopus 로고
    • Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner
    • Antonucci T.K., Rutter W.J. Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner. J. Virol. 63:1989;579-583.
    • (1989) J. Virol. , vol.63 , pp. 579-583
    • Antonucci, T.K.1    Rutter, W.J.2
  • 17
    • 0030825362 scopus 로고    scopus 로고
    • Human hepatitis B virus enhancer 1 is responsive to human interleukin-6
    • Ohno H., Kaneko S., Kobayashi K., Murakami S. Human hepatitis B virus enhancer 1 is responsive to human interleukin-6. J. Med. Virol. 52:1997;413-418.
    • (1997) J. Med. Virol. , vol.52 , pp. 413-418
    • Ohno, H.1    Kaneko, S.2    Kobayashi, K.3    Murakami, S.4
  • 18
    • 0025277829 scopus 로고
    • Differentiation-specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell lines
    • Raney A.K., Milich D.R., Easton A.J., McLachlan A. Differentiation-specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell lines. J. Virol. 64:1990;2360-2368.
    • (1990) J. Virol. , vol.64 , pp. 2360-2368
    • Raney, A.K.1    Milich, D.R.2    Easton, A.J.3    McLachlan, A.4
  • 19
    • 0031664154 scopus 로고    scopus 로고
    • Metabolic labeling of woodchuck hepatitis B virus X protein in naturally infected hepatocytes reveals a bimodal half-life and association with the nuclear framework
    • Dandri M., Petersen J., Stockert R.J., Harris T.M., Rogler C.E. Metabolic labeling of woodchuck hepatitis B virus X protein in naturally infected hepatocytes reveals a bimodal half-life and association with the nuclear framework. J. Virol. 72:1998;9359-9364.
    • (1998) J. Virol. , vol.72 , pp. 9359-9364
    • Dandri, M.1    Petersen, J.2    Stockert, R.J.3    Harris, T.M.4    Rogler, C.E.5
  • 20
    • 0026005668 scopus 로고
    • Phosphorylation and rapid turnover of hepatitis B virus X-protein expressed in HepG2 cells from a recombinant vaccinia virus
    • Schek N., Bartenschlager R., Kuhn C., Schaller H. Phosphorylation and rapid turnover of hepatitis B virus X-protein expressed in HepG2 cells from a recombinant vaccinia virus. Oncogene. 6:1991;1735-1744.
    • (1991) Oncogene , vol.6 , pp. 1735-1744
    • Schek, N.1    Bartenschlager, R.2    Kuhn, C.3    Schaller, H.4
  • 21
    • 0036278326 scopus 로고    scopus 로고
    • Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex
    • Bergametti F., Sitterlin D., Transy C. Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex. J. Virol. 76:2002;6495-6501.
    • (2002) J. Virol. , vol.76 , pp. 6495-6501
    • Bergametti, F.1    Sitterlin, D.2    Transy, C.3
  • 22
    • 0034673319 scopus 로고    scopus 로고
    • Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis
    • Lee S.W., Lee Y.M., Bae S.K., Murakami S., Yun Y., Kim K.W. Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis. Biochem. Biophys. Res. Commun. 268:2000;456-461.
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 456-461
    • Lee, S.W.1    Lee, Y.M.2    Bae, S.K.3    Murakami, S.4    Yun, Y.5    Kim, K.W.6
  • 23
    • 0034718770 scopus 로고    scopus 로고
    • Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein expressing liver cells
    • Yun C., Lee J.H., Park H., Jin Y.M., Park S., Park K., Cho H. Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein expressing liver cells. Oncogene. 19:2000;5163-5172.
    • (2000) Oncogene , vol.19 , pp. 5163-5172
    • Yun, C.1    Lee, J.H.2    Park, H.3    Jin, Y.M.4    Park, S.5    Park, K.6    Cho, H.7
  • 24
    • 0036392176 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X (HBx) gene is up-regulated by adriamycin at the post-transcriptional level
    • Yun C., Lee J.H., Wang J.H., Seong J.K., Oh S.H., Yu D.Y., Cho H. Expression of hepatitis B virus X (HBx) gene is up-regulated by adriamycin at the post-transcriptional level. Biochem. Biophys. Res. Commun. 296:2002;1157-1163.
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 1157-1163
    • Yun, C.1    Lee, J.H.2    Wang, J.H.3    Seong, J.K.4    Oh, S.H.5    Yu, D.Y.6    Cho, H.7
  • 25
    • 0000934401 scopus 로고
    • Production of hepatitis B virus particles in HepG2 cells transfected with cloned hepatitis B virus DNA
    • Selles M.A., Chen M.L., Acs G. Production of hepatitis B virus particles in HepG2 cells transfected with cloned hepatitis B virus DNA. Proc. Natl. Acad. Sci. USA. 84:1987;1005-1009.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1005-1009
    • Selles, M.A.1    Chen, M.L.2    Acs, G.3
  • 26
    • 0017030796 scopus 로고
    • Establishment of a continuously growing cell line from primary carcinoma of the liver
    • Alexander J.J., Bey E.M., Geddes E.W., Lecatsas G. Establishment of a continuously growing cell line from primary carcinoma of the liver. S. Afr. Med. J. 5:1976;2124-2128.
    • (1976) S. Afr. Med. J. , vol.5 , pp. 2124-2128
    • Alexander, J.J.1    Bey, E.M.2    Geddes, E.W.3    Lecatsas, G.4
  • 27
    • 0035909521 scopus 로고    scopus 로고
    • HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer
    • Shamay M., Agami R., Shaul Y. HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer. Oncogene. 20:2001;6811-6819.
    • (2001) Oncogene , vol.20 , pp. 6811-6819
    • Shamay, M.1    Agami, R.2    Shaul, Y.3
  • 28
    • 0036681850 scopus 로고    scopus 로고
    • Antioxidant alpha-keto-carboxylate pyruvate protects low-density lipoprotein and atherogenic macrophages
    • Kang Y.H., Park S.H., Lee Y.J., Kang J.S., Kang I.J., Shin H.K., Park J.H., Bunger R. Antioxidant alpha-keto-carboxylate pyruvate protects low-density lipoprotein and atherogenic macrophages. Free Radic. Res. 36:2002;905-914.
    • (2002) Free Radic. Res. , vol.36 , pp. 905-914
    • Kang, Y.H.1    Park, S.H.2    Lee, Y.J.3    Kang, J.S.4    Kang, I.J.5    Shin, H.K.6    Park, J.H.7    Bunger, R.8
  • 29
    • 0034445689 scopus 로고    scopus 로고
    • Long-term results of lipiodol-transcatheter arterial embolization with cisplatin or doxorubicin for unresectable hepatocellular carcinoma
    • Ono Y., Yoshimasu T., Ashikaga R., Inoue M., Shindou H., Fuji K., Araki Y., Nishimura Y. Long-term results of lipiodol-transcatheter arterial embolization with cisplatin or doxorubicin for unresectable hepatocellular carcinoma. Am. J. Clin. Oncol. 23:2000;564-568.
    • (2000) Am. J. Clin. Oncol. , vol.23 , pp. 564-568
    • Ono, Y.1    Yoshimasu, T.2    Ashikaga, R.3    Inoue, M.4    Shindou, H.5    Fuji, K.6    Araki, Y.7    Nishimura, Y.8
  • 30
    • 0035912594 scopus 로고    scopus 로고
    • Doxorubicin-induced persistent oxidative stress to cardiac myocytes
    • Zhou S., Palmeira C.M., Wallace K.B. Doxorubicin-induced persistent oxidative stress to cardiac myocytes. Toxicol. Lett. 121:2001;151-157.
    • (2001) Toxicol. Lett. , vol.121 , pp. 151-157
    • Zhou, S.1    Palmeira, C.M.2    Wallace, K.B.3
  • 32
    • 0032816238 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex
    • Hu Z., Zhang Z., Doo E., Coux O., Goldberg A.L., Liang T.J. Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex. J. Virol. 73:1999;7231-7240.
    • (1999) J. Virol. , vol.73 , pp. 7231-7240
    • Hu, Z.1    Zhang, Z.2    Doo, E.3    Coux, O.4    Goldberg, A.L.5    Liang, T.J.6
  • 33
    • 0029034231 scopus 로고
    • HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit
    • Fischer M., Runkel L., Schaller H. HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit. Virus Genes. 10:1995;99-102.
    • (1995) Virus Genes. , vol.10 , pp. 99-102
    • Fischer, M.1    Runkel, L.2    Schaller, H.3
  • 34
    • 0032559971 scopus 로고    scopus 로고
    • Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome
    • Sirma H., Weil R., Rosmorduc O., Urban S., Israel A., Kremsdorf D., Brechot C. Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome. Oncogene. 16:1998;2051-2063.
    • (1998) Oncogene , vol.16 , pp. 2051-2063
    • Sirma, H.1    Weil, R.2    Rosmorduc, O.3    Urban, S.4    Israel, A.5    Kremsdorf, D.6    Brechot, C.7
  • 35
    • 0034685805 scopus 로고    scopus 로고
    • Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex
    • Zhang Z., Torii N., Furusaka A., Malayaman N., Hu Z., Liang T.J. Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex. J. Biol. Chem. 275:2000;15157-15165.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15157-15165
    • Zhang, Z.1    Torii, N.2    Furusaka, A.3    Malayaman, N.4    Hu, Z.5    Liang, T.J.6
  • 36
    • 0342905085 scopus 로고    scopus 로고
    • Hepatitis B virus Xprotein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential
    • Rahmani Z., Huh K.W., Lasher R., Siddiqui A. Hepatitis B virus Xprotein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential. J. Virol. 74:2000;2840-2846.
    • (2000) J. Virol. , vol.74 , pp. 2840-2846
    • Rahmani, Z.1    Huh, K.W.2    Lasher, R.3    Siddiqui, A.4
  • 37
    • 0033604446 scopus 로고    scopus 로고
    • Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death
    • Akada S., Shirakata Y., Kaneniwa N., Koike K. Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death. Oncogene. 18:1999;6965-6973.
    • (1999) Oncogene , vol.18 , pp. 6965-6973
    • Akada, S.1    Shirakata, Y.2    Kaneniwa, N.3    Koike, K.4
  • 38
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-κ B via oxidative stress
    • Waris G., Huh K.W., Siddiqui A. Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-κ B via oxidative stress. J. Virol. 21:2001;7721-7730.
    • (2001) J. Virol. , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 42
    • 0031746396 scopus 로고    scopus 로고
    • Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells
    • Lee Y., Park U.S., Choi I., Yoon S.K., Park Y.M., Lee Y.I. Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells. Clin. Cancer Res. 4:1998;1711-1717.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1711-1717
    • Lee, Y.1    Park, U.S.2    Choi, I.3    Yoon, S.K.4    Park, Y.M.5    Lee, Y.I.6
  • 43
    • 0034987518 scopus 로고    scopus 로고
    • Possible role of human interleukin-6 and soluble interleukin-6 receptor in hepatitis B virus infection
    • Heinz D., Peters M., Prange R., Gerken G., Rose-John S. Possible role of human interleukin-6 and soluble interleukin-6 receptor in hepatitis B virus infection. J. Viral Hepat. 8:2001;186-193.
    • (2001) J. Viral Hepat. , vol.8 , pp. 186-193
    • Heinz, D.1    Peters, M.2    Prange, R.3    Gerken, G.4    Rose-John, S.5
  • 44
    • 0036190849 scopus 로고    scopus 로고
    • Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function
    • Waris G., Siddiqui A. Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function. J. Virol. 76:2002;2721-2729.
    • (2002) J. Virol. , vol.76 , pp. 2721-2729
    • Waris, G.1    Siddiqui, A.2


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