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Volumn 115, Issue SUPPL.1, 2013, Pages

Challenges in multiple sclerosis; How to define occurence of progression

Author keywords

MRI in MS brain atrophy; Multiple sclerosis; Natural history studies; Pathology; Therapy of MS

Indexed keywords

IMMUNOMODULATING AGENT; MYELIN;

EID: 84890027447     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2013.09.017     Document Type: Article
Times cited : (10)

References (85)
  • 1
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • A. Compston, and A. Coles Multiple sclerosis Lancet 25 372 2008 1502 1517
    • (2008) Lancet , vol.25 , Issue.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 2
    • 81555223903 scopus 로고    scopus 로고
    • The molecular basis of neurodegeneration in multiple sclerosis
    • H. Lassmann, and J. van Horssen The molecular basis of neurodegeneration in multiple sclerosis FEBS Lett 585 2011 3715 3723
    • (2011) FEBS Lett , vol.585 , pp. 3715-3723
    • Lassmann, H.1    Van Horssen, J.2
  • 3
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study I. Clinical course and disability
    • B.G. Weinschenker, B. Bass, and G.P. Rice The natural history of multiple sclerosis: a geographically based study I. Clinical course and disability Brain 112 1989 133 146
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinschenker, B.G.1    Bass, B.2    Rice, G.P.3
  • 4
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study.2. Predictive value of the early clinical course
    • B.G. Weinschenker, B. Bass, and G.P. Rice The natural history of multiple sclerosis: a geographically based study.2. Predictive value of the early clinical course Brain 112 1989 133 146
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinschenker, B.G.1    Bass, B.2    Rice, G.P.3
  • 5
    • 0344738667 scopus 로고    scopus 로고
    • Effect of relapse on development of residual deficit in multiple sclerosis
    • F.D. Lublin, M. Baier, and G. Cutter Effect of relapse on development of residual deficit in multiple sclerosis Neurology 61 2003 1528 1532
    • (2003) Neurology , vol.61 , pp. 1528-1532
    • Lublin, F.D.1    Baier, M.2    Cutter, G.3
  • 7
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: Relationship to neurologic disability
    • Review
    • B.D. Trapp, R. Ransohoff, and R. Rudick Axonal pathology in multiple sclerosis: relationship to neurologic disability Curr Opin Neurol 12 1999 295 302 Review
    • (1999) Curr Opin Neurol , vol.12 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 8
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • B. Ferguson, M.K. Matyszak, and M.M. Esiri Axonal damage in acute multiple sclerosis lesions Brain 120 1997 393 399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3
  • 9
    • 0033849266 scopus 로고    scopus 로고
    • Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis
    • N. Evangelou, D. Konz, and M.M. Esiri Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis Brain 123 2000 1845 1849
    • (2000) Brain , vol.123 , pp. 1845-1849
    • Evangelou, N.1    Konz, D.2    Esiri, M.M.3
  • 10
    • 0036788406 scopus 로고    scopus 로고
    • Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
    • T. Kuhlmann, G. Lingfeld, and A. Bitsch Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time Brain 125 Pt 10 2002 2202 2212
    • (2002) Brain , vol.125 , Issue.PART 10 , pp. 2202-2212
    • Kuhlmann, T.1    Lingfeld, G.2    Bitsch, A.3
  • 11
    • 0028815032 scopus 로고
    • Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: A follow-up study
    • Feb
    • M. Filippi, D.W. Paty, and L. Kappos Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: a follow-up study Neurology 45 2 1995 255 260 Feb
    • (1995) Neurology , vol.45 , Issue.2 , pp. 255-260
    • Filippi, M.1    Paty, D.W.2    Kappos, L.3
  • 12
    • 0033256112 scopus 로고    scopus 로고
    • Non-conventional MR techniques in monitoring MS activity and evolution
    • Review
    • M. Filippi Non-conventional MR techniques in monitoring MS activity and evolution Electroencephalogr Clin Neurophysiol Suppl 50 1999 565 569 Review
    • (1999) Electroencephalogr Clin Neurophysiol Suppl , vol.50 , pp. 565-569
    • Filippi, M.1
  • 13
    • 0037312536 scopus 로고    scopus 로고
    • Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis
    • M. Filippi, M. Bozzali, and M. Rovaris Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis Brain 126 2003 433 437
    • (2003) Brain , vol.126 , pp. 433-437
    • Filippi, M.1    Bozzali, M.2    Rovaris, M.-A.L.3
  • 14
    • 0027503708 scopus 로고
    • Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis
    • D. Katz, J.K. Taubenberger, and B. Cannella Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis Ann Neurol 34 1993 661 669
    • (1993) Ann Neurol , vol.34 , pp. 661-669
    • Katz, D.1    Taubenberger, J.K.2    Cannella, B.3
  • 15
    • 0037379402 scopus 로고    scopus 로고
    • Early clinical predictors and progression of irreversible disability: An amnestic process
    • C. Confavreux, S. Vukusic, and P. Adeleine Early clinical predictors and progression of irreversible disability: an amnestic process Brain 126 Pt 4 2003 770 782
    • (2003) Brain , vol.126 , Issue.PART 4 , pp. 770-782
    • Confavreux, C.1    Vukusic, S.2    Adeleine, P.3
  • 16
    • 33244486947 scopus 로고    scopus 로고
    • The natural history of multiple sclerosis: A geographically based study 9: Observations on the progressive phase of disease
    • M. Kremenchutzky, G.P.A. Rice, and J. Baskerville The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of disease Brain 129 2006 584 594
    • (2006) Brain , vol.129 , pp. 584-594
    • Kremenchutzky, M.1    Rice, G.P.A.2    Baskerville, J.3
  • 17
    • 33244466021 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: A unifying concept
    • C. Confavreux, and S. Vukusic Natural history of multiple sclerosis: a unifying concept Brain 129 2006 a 606 616
    • (2006) Brain , vol.129 , pp. 606-616
    • Confavreux, C.1    Vukusic, S.2
  • 18
    • 33244469927 scopus 로고    scopus 로고
    • Age at disability milestones in multiple sclerosis
    • C. Confavreux, and S. Vukusic Age at disability milestones in multiple sclerosis Brain 129 2006 b 595 605
    • (2006) Brain , vol.129 , pp. 595-605
    • Confavreux, C.1    Vukusic, S.2
  • 19
    • 73449141779 scopus 로고    scopus 로고
    • Impact of multiple sclerosis on progression diminished with time
    • H. Tremlett, M. Yousefi, and V. Devonshire Impact of multiple sclerosis on progression diminished with time Neurology 73 2009 1616 1623
    • (2009) Neurology , vol.73 , pp. 1616-1623
    • Tremlett, H.1    Yousefi, M.2    Devonshire, V.3
  • 22
    • 0036136532 scopus 로고    scopus 로고
    • Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis
    • J.R. Wujek, C. Bjartmar, and E. Richer Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis J Neuropathol Exp Neurol 61 1 2002 23 32
    • (2002) J Neuropathol Exp Neurol , vol.61 , Issue.1 , pp. 23-32
    • Wujek, J.R.1    Bjartmar, C.2    Richer, E.3
  • 23
    • 0342288638 scopus 로고    scopus 로고
    • Axonal changes in chronic demyelinated cervical spinal cord plaques
    • Feb
    • G. Lovas, N. Szilágyi, and K. Majtényi Axonal changes in chronic demyelinated cervical spinal cord plaques Brain 123 2000 308 317 Feb
    • (2000) Brain , vol.123 , pp. 308-317
    • Lovas, G.1    Szilágyi, N.2    Majtényi, K.3
  • 24
    • 0037441487 scopus 로고    scopus 로고
    • Axonal loss in the pathology of MS: Consequences for understanding the progressive phase of disease
    • C. Bjatmar, J.R. Wujek, and B.D. Trapp Axonal loss in the pathology of MS: consequences for understanding the progressive phase of disease J Neurol Sci 15 206 2003 165 171
    • (2003) J Neurol Sci , vol.15 , Issue.206 , pp. 165-171
    • Bjatmar, C.1    Wujek, J.R.2    Trapp, B.D.3
  • 25
    • 11244305515 scopus 로고    scopus 로고
    • Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions
    • N. Evangelou, G.C. DeLuca, and T. Owens Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions Brain 128 2005 29
    • (2005) Brain , vol.128 , pp. 29
    • Evangelou, N.1    Deluca, G.C.2    Owens, T.3
  • 26
    • 2442555263 scopus 로고    scopus 로고
    • Axonal loss in multiple sclerosis: A pathological survey of the corticospinal and sensory tracts
    • G.C. DeLuca, G.C. Ebers, and M.M. Esiri Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts Brain 127 2004 1009 1018
    • (2004) Brain , vol.127 , pp. 1009-1018
    • Deluca, G.C.1    Ebers, G.C.2    Esiri, M.M.3
  • 27
    • 33745115644 scopus 로고    scopus 로고
    • The contribution of demyelination to axonal loss in multiple sclerosis
    • G.C. DeLuca, K. Williams, and N. Evangelou The contribution of demyelination to axonal loss in multiple sclerosis Brain 129 2006 1507 1516
    • (2006) Brain , vol.129 , pp. 1507-1516
    • Deluca, G.C.1    Williams, K.2    Evangelou, N.3
  • 28
    • 82555194254 scopus 로고    scopus 로고
    • Relapses do not matter in relation to long-term disability: Yes
    • C. Casserly, and G. Ebers Relapses do not matter in relation to long-term disability: yes MSJ 17 12 2011 1412 1414
    • (2011) MSJ , vol.17 , Issue.12 , pp. 1412-1414
    • Casserly, C.1    Ebers, G.2
  • 29
    • 82555176751 scopus 로고    scopus 로고
    • Relapses do not matter inrelation to long-term disability: No (they do)
    • F.D. Lublin Relapses do not matter inrelation to long-term disability: no (they do) MSJ 17 12 2011 1415 1416
    • (2011) MSJ , vol.17 , Issue.12 , pp. 1415-1416
    • Lublin, F.D.1
  • 30
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • B.D. Trapp, and K.A. Nave Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31 2008 247 269
    • (2008) Annu Rev Neurosci , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.A.2
  • 31
    • 34447093998 scopus 로고    scopus 로고
    • Multiple sclerosis: Is there neurodegeneration independent frinflammation?
    • H. Lassmann Multiple sclerosis: is there neurodegeneration independent frinflammation? J Neurol Sci 259 2007 3 6
    • (2007) J Neurol Sci , vol.259 , pp. 3-6
    • Lassmann, H.1
  • 32
    • 0018394631 scopus 로고
    • A histochemical and biochemical study of macroscopically normal white matter in multiple sclerosis
    • 81-81
    • I.V. Allen, and S.R. McKeown A histochemical and biochemical study of macroscopically normal white matter in multiple sclerosis J Neurol Sci 41 1979 81-81
    • (1979) J Neurol Sci , vol.41
    • Allen, I.V.1    McKeown, S.R.2
  • 33
    • 0035833965 scopus 로고    scopus 로고
    • Axonal loss in normal-appearing white matter in a patient with acute MS
    • C. Bjartmar, R.P. Kinkel, and G. Kidd Axonal loss in normal-appearing white matter in a patient with acute MS Neurology 57 2001 1248 1252
    • (2001) Neurology , vol.57 , pp. 1248-1252
    • Bjartmar, C.1    Kinkel, R.P.2    Kidd, G.3
  • 34
    • 0034104079 scopus 로고    scopus 로고
    • Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis
    • N. Evangelou, M.M. Esiri, and S. Smith Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis Ann Neurol 47 2000 391 395
    • (2000) Ann Neurol , vol.47 , pp. 391-395
    • Evangelou, N.1    Esiri, M.M.2    Smith, S.3
  • 35
    • 27644552194 scopus 로고    scopus 로고
    • Cortical demyelination and diffuse white matter injury in multiple sclerosis
    • A. Kutzelnigg, C.F. Lucchinetti, and C. Stadelmann Cortical demyelination and diffuse white matter injury in multiple sclerosis Brain 128 2005 2705 2712
    • (2005) Brain , vol.128 , pp. 2705-2712
    • Kutzelnigg, A.1    Lucchinetti, C.F.2    Stadelmann, C.3
  • 36
    • 66249131627 scopus 로고    scopus 로고
    • Diffusely abnormal white matter in chronic multiple sclerosis: Imaging and histopathologic analysis
    • A. Seewann, H. Vrenken, and P. van der Valk Diffusely abnormal white matter in chronic multiple sclerosis: imaging and histopathologic analysis Arch Neurol 66 2009 601 609
    • (2009) Arch Neurol , vol.66 , pp. 601-609
    • Seewann, A.1    Vrenken, H.2    Van Der Valk, P.3
  • 38
    • 0001362922 scopus 로고
    • The distribution of plaques in the cerebrum in multiple sclerosis
    • B. Brownell, and J.T. Hughes The distribution of plaques in the cerebrum in multiple sclerosis J Neurol Neurosurg Psychiatry 25 1962 315 320
    • (1962) J Neurol Neurosurg Psychiatry , vol.25 , pp. 315-320
    • Brownell, B.1    Hughes, J.T.2
  • 39
    • 0032935470 scopus 로고    scopus 로고
    • Cortical lesions in multiple sclerosis
    • D. Kid, B. Barkhof, and R. McConnell Cortical lesions in multiple sclerosis Brain 122 1999 7 26
    • (1999) Brain , vol.122 , pp. 7-26
    • Kid, D.1    Barkhof, B.2    McConnell, R.3
  • 40
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • J.W. Peterson, L. Bo, and S. Mork Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions Ann Neurol 50 2001 389 400
    • (2001) Ann Neurol , vol.50 , pp. 389-400
    • Peterson, J.W.1    Bo, L.2    Mork, S.3
  • 41
    • 48849116689 scopus 로고    scopus 로고
    • Grey matter pathology in multiple sclerosis
    • J.J. Geurts, and F. Barkhof Grey matter pathology in multiple sclerosis Lancet Neurol 7 9 2008 841 851
    • (2008) Lancet Neurol , vol.7 , Issue.9 , pp. 841-851
    • Geurts, J.J.1    Barkhof, F.2
  • 42
    • 0037828315 scopus 로고    scopus 로고
    • Subpial demyelination in cerebral cortex of multiple sclerosis patients
    • I. Bo, C.A. Vedeler, and H.L. Nyland Subpial demyelination in cerebral cortex of multiple sclerosis patients J Neuropath Exp Neurol 62 2003 723 732
    • (2003) J Neuropath Exp Neurol , vol.62 , pp. 723-732
    • Bo, I.1    Vedeler, C.A.2    Nyland, H.L.3
  • 44
    • 0035087229 scopus 로고    scopus 로고
    • Epileptic and non-epileptic seizures in multiple sclerosis
    • J. Spat, ChaixR, and B. Mamoli Epileptic and non-epileptic seizures in multiple sclerosis J Neurol 248 2001 2 9
    • (2001) J Neurol , vol.248 , pp. 2-9
    • Spat, J.1    Chaix, R.2    Mamoli, B.3
  • 45
    • 3242660753 scopus 로고    scopus 로고
    • Neocortical volume decrease in relapsing remitting MS patients with mild cognitive impairment
    • M.P. Amato, BartolozziMI, and V. Zipoli Neocortical volume decrease in relapsing remitting MS patients with mild cognitive impairment Neurology 63 2004 89 93
    • (2004) Neurology , vol.63 , pp. 89-93
    • Amato, M.P.1    Bartolozzi, M.I.2    Zipoli, V.3
  • 46
    • 33847227721 scopus 로고    scopus 로고
    • Widespread demyelination in cerebellar cortex in multiple sclerosis
    • A. Kutzelnigg, J.C. Faber-Rod, and J. Bauer Widespread demyelination in cerebellar cortex in multiple sclerosis Brain Pathol 17 2007 38 44
    • (2007) Brain Pathol , vol.17 , pp. 38-44
    • Kutzelnigg, A.1    Faber-Rod, J.C.2    Bauer, J.3
  • 47
    • 60249099507 scopus 로고    scopus 로고
    • Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: A comparison between the cerebral cortex, cerebellar cortex, deep grey matter and spinal cord
    • C.P. Gilmore, I. Donaldson, and L. Bo Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter and spinal cord J Neurol Neurosurg Psychiatry 80 2 2009 182 187
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , Issue.2 , pp. 182-187
    • Gilmore, C.P.1    Donaldson, I.2    Bo, L.3
  • 48
    • 67749146330 scopus 로고    scopus 로고
    • Spinal cord neuronal pathology in multiple sclerosis
    • C.P. Gilmore, G.C. DeLuca, and L. Bö Spinal cord neuronal pathology in multiple sclerosis Brain Pathol 19 4 2009 642 649
    • (2009) Brain Pathol , vol.19 , Issue.4 , pp. 642-649
    • Gilmore, C.P.1    Deluca, G.C.2    Bö, L.3
  • 49
    • 33846093882 scopus 로고    scopus 로고
    • Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis
    • L. Bö, J.J. Geurts, and P. van der Valk Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis Arch Neurol J 64 1 2007 76 80
    • (2007) Arch Neurol J , vol.64 , Issue.1 , pp. 76-80
    • Bö, L.1    Geurts, J.J.2    Van Der Valk, P.3
  • 50
    • 0042123685 scopus 로고    scopus 로고
    • Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
    • L. Bø, C.A. Vedeler, and H. Nyland Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration Mult Scler 9 4 2003 323 331
    • (2003) Mult Scler , vol.9 , Issue.4 , pp. 323-331
    • Bø, L.1    Vedeler, C.A.2    Nyland, H.3
  • 51
    • 14844293538 scopus 로고    scopus 로고
    • The pathology of multiple sclerosis is location-dependent: No significant complement activation is detected in purely cortical lesions
    • B.P. Brink, R. Veerhuis, and E.C. Breij The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions J Neuropath Exp Neurol 64 2005 147 155
    • (2005) J Neuropath Exp Neurol , vol.64 , pp. 147-155
    • Brink, B.P.1    Veerhuis, R.2    Breij, E.C.3
  • 53
    • 79960842695 scopus 로고    scopus 로고
    • A dynamic view of the blood brain barrier in active multiple sclerosis lesions
    • H. Lassmann A dynamic view of the blood brain barrier in active multiple sclerosis lesions Ann Neurol 70 2011 1 2
    • (2011) Ann Neurol , vol.70 , pp. 1-2
    • Lassmann, H.1
  • 54
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • R. Magliozzi, O. Howell, and A. Vora Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology Brain 130 2007 1089 1104
    • (2007) Brain , vol.130 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3
  • 55
    • 80052927697 scopus 로고    scopus 로고
    • Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
    • O.W. Howell, C.A. Reeves, R. Nicholas, and D. Carassiti Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis Brain 134 Pt 9 2011 2755 2771
    • (2011) Brain , vol.134 , Issue.PART 9 , pp. 2755-2771
    • Howell, O.W.1    Reeves, C.A.2    Nicholas, R.3    Carassiti, D.4
  • 56
    • 70349577131 scopus 로고    scopus 로고
    • Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis
    • E.J. Kooi, J.J. Geurts, and J. van Horssen Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis J Neuropathol Exp Neurol 68 9 2009 1021 1028
    • (2009) J Neuropathol Exp Neurol , vol.68 , Issue.9 , pp. 1021-1028
    • Kooi, E.J.1    Geurts, J.J.2    Van Horssen, J.3
  • 57
    • 83155173565 scopus 로고    scopus 로고
    • Inflammatory cortical demyelination in early multiple sclerosis
    • C. Lucchinetti, and F. Popescu Inflammatory cortical demyelination in early multiple sclerosis N Engl J Med 365 23 2011 2188 2197
    • (2011) N Engl J Med , vol.365 , Issue.23 , pp. 2188-2197
    • Lucchinetti, C.1    Popescu, F.2
  • 58
    • 79957492193 scopus 로고    scopus 로고
    • A case of multiple sclerosis presenting with inflammatory cortical demyelination
    • B. Popescu, R. Bunyan, and J. Parisi A case of multiple sclerosis presenting with inflammatory cortical demyelination Neurology 76 2011 1705 1710
    • (2011) Neurology , vol.76 , pp. 1705-1710
    • Popescu, B.1    Bunyan, R.2    Parisi, J.3
  • 59
    • 84859100978 scopus 로고    scopus 로고
    • Menigeal and cortical grey matter pathology in multiple sclerosis
    • B. Popescu, and C. Lucchinetti Menigeal and cortical grey matter pathology in multiple sclerosis BMC Neurol 12 2012 1 8
    • (2012) BMC Neurol , vol.12 , pp. 1-8
    • Popescu, B.1    Lucchinetti, C.2
  • 60
    • 0037465364 scopus 로고    scopus 로고
    • MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals
    • F. Cotton, H.L. Weiner, and F.A. Jolesz MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals Neurology 2003 606064 606146
    • (2003) Neurology , pp. 606064-606146
    • Cotton, F.1    Weiner, H.L.2    Jolesz, F.A.3
  • 61
    • 80053588889 scopus 로고    scopus 로고
    • Imaging the tip of the iceberg;visualisation of cortical lesions in multiple sclerosis
    • A. Seewann, H. Vrenken, and D.L. Kooi Imaging the tip of the iceberg;visualisation of cortical lesions in multiple sclerosis Mult Scler 2011
    • (2011) Mult Scler
    • Seewann, A.1    Vrenken, H.2    Kooi, D.L.3
  • 62
    • 16844364980 scopus 로고    scopus 로고
    • Cortical lesions in multiple sclerosis presenting combined postmorten MR imaging and histopathology
    • J.J. Geurts, L. Bo, and P. Powels Cortical lesions in multiple sclerosis presenting combined postmorten MR imaging and histopathology AJNR - Am J Neurorad 26 2007 572 577
    • (2007) AJNR - Am J Neurorad , vol.26 , pp. 572-577
    • Geurts, J.J.1    Bo, L.2    Powels, P.3
  • 63
    • 0035088438 scopus 로고    scopus 로고
    • Magnetisation transfer ratio and mean diffusity of normal appearing white and grey matter from patients with multiple sclerosis
    • M. Cercignani, M. Bozzali, and G. Iannucci Magnetisation transfer ratio and mean diffusity of normal appearing white and grey matter from patients with multiple sclerosis J Neurol Neurosurg Psichiatry 70 2001 311 317
    • (2001) J Neurol Neurosurg Psichiatry , vol.70 , pp. 311-317
    • Cercignani, M.1    Bozzali, M.2    Iannucci, G.3
  • 64
    • 33747589457 scopus 로고    scopus 로고
    • Whole brain T1 mapping in multiple sclerosis:global changes of normal-appearing gray and white matter
    • H. Vrenken, J.J. Geurts, and D.I. Knol Whole brain T1 mapping in multiple sclerosis:global changes of normal-appearing gray and white matter Radiology 240 2006 811 820
    • (2006) Radiology , vol.240 , pp. 811-820
    • Vrenken, H.1    Geurts, J.J.2    Knol, D.I.3
  • 65
    • 33644802314 scopus 로고    scopus 로고
    • MR spectroscopic evidence for thalamic and hippocampal but not cortical damage in multiple sclerosis
    • J.J. Geurts, I.E. Reuling, and H. Vrenken MR spectroscopic evidence for thalamic and hippocampal but not cortical damage in multiple sclerosis Magn Reson Med 55 2006 478 483
    • (2006) Magn Reson Med , vol.55 , pp. 478-483
    • Geurts, J.J.1    Reuling, I.E.2    Vrenken, H.3
  • 66
    • 77954819068 scopus 로고    scopus 로고
    • Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla
    • B. Simon, S. Schmidt, and C. Lukas Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla Eur Radiol 20 2010 1675 1680
    • (2010) Eur Radiol , vol.20 , pp. 1675-1680
    • Simon, B.1    Schmidt, S.2    Lukas, C.3
  • 67
    • 77954819068 scopus 로고    scopus 로고
    • Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Telsa
    • July
    • S. Birgit, S. Stephan, and L. Carsten Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Telsa Eur Radiol 20 7 2010 1675 1680 July
    • (2010) Eur Radiol , vol.20 , Issue.7 , pp. 1675-1680
    • Birgit, S.1    Stephan, S.2    Carsten, L.3
  • 68
  • 69
    • 58149095079 scopus 로고    scopus 로고
    • Evidence for relative cortical sparing in benign multiple sclerosis: A longitudinal magnetic resonance imaging study
    • M. Calabrese, M. Fillipi, and M. Rovaris Evidence for relative cortical sparing in benign multiple sclerosis: a longitudinal magnetic resonance imaging study Mult Scler 15 2009 36 41
    • (2009) Mult Scler , vol.15 , pp. 36-41
    • Calabrese, M.1    Fillipi, M.2    Rovaris, M.3
  • 70
    • 54849431166 scopus 로고    scopus 로고
    • Gray matter atrophy in multiple sclerosis: A longitudinal study
    • E. Fisher, J.C. Lee, and K. Nakamura Gray matter atrophy in multiple sclerosis: a longitudinal study Ann Neurol 64 2008 255 265
    • (2008) Ann Neurol , vol.64 , pp. 255-265
    • Fisher, E.1    Lee, J.C.2    Nakamura, K.3
  • 71
    • 70349673301 scopus 로고    scopus 로고
    • In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI
    • C.C. Mainero, T. Benner, and A. Radding In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI Neurology 73 2009 941 948
    • (2009) Neurology , vol.73 , pp. 941-948
    • Mainero, C.C.1    Benner, T.2    Radding, A.3
  • 72
    • 84877743492 scopus 로고    scopus 로고
    • Imaging cortical damage and dysfunction in multiple sclerosis
    • M. Filippi, M.A. Rocca, and M.A. Horsfield Imaging cortical damage and dysfunction in multiple sclerosis JAMA Neurol 70 5 2013 May 556 564
    • (2013) JAMA Neurol , vol.70 , Issue.5 , pp. 556-564
    • Filippi, M.1    Rocca, M.A.2    Horsfield, M.A.3
  • 73
    • 84876720350 scopus 로고    scopus 로고
    • Multicontrast MR imaging at 7 T in multiple sclerosis: Highest lesion detection in cortical gray matter with 3D-FLAIR
    • I.D. Kilsdonk, W.L. de Graaf, and A.L. Soriano Multicontrast MR imaging at 7 T in multiple sclerosis: highest lesion detection in cortical gray matter with 3D-FLAIR AJNR Am J Neuroradiol 34 4 2013 791 796
    • (2013) AJNR Am J Neuroradiol , vol.34 , Issue.4 , pp. 791-796
    • Kilsdonk, I.D.1    De Graaf, W.L.2    Soriano, A.L.3
  • 74
    • 84865295471 scopus 로고    scopus 로고
    • Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis
    • S. Hannoun, F. Durand-Dubief, and C. Confavreux Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis AJNR Am J Neuroradiol 33 7 2012 1363 1368
    • (2012) AJNR Am J Neuroradiol , vol.33 , Issue.7 , pp. 1363-1368
    • Hannoun, S.1    Durand-Dubief, F.2    Confavreux, C.3
  • 75
    • 83155178492 scopus 로고    scopus 로고
    • Gray matter imaging in multiple sclerosis: What have we learned?
    • H.E. Hulst, and J. Geurts Gray matter imaging in multiple sclerosis: what have we learned? BMC Neurol 11 2011 153
    • (2011) BMC Neurol , vol.11 , pp. 153
    • Hulst, H.E.1    Geurts, J.2
  • 76
    • 0036830526 scopus 로고    scopus 로고
    • Thalamic neurodegeneration in multiple sclerosis
    • A. Cifelli, ArridgeM, and P. Jezzard Thalamic neurodegeneration in multiple sclerosis Ann Neurol 53 2002 650 653
    • (2002) Ann Neurol , vol.53 , pp. 650-653
    • Cifelli, A.1    Arridge, N.2    Jezzard, P.3
  • 77
    • 84885413852 scopus 로고    scopus 로고
    • Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years
    • R. Zivadinov, N. Bergsland, and O. Dolezal Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years AJNR - Am J Neuroradiol 2013
    • (2013) AJNR - Am J Neuroradiol
    • Zivadinov, R.1    Bergsland, N.2    Dolezal, O.3
  • 78
    • 33748997359 scopus 로고    scopus 로고
    • Neocortical, neuronal, synaptic and glial loss in multiple sclerosis
    • C. Wegner, M.M. Esiri, and S.A. Chance Neocortical, neuronal, synaptic and glial loss in multiple sclerosis Neurology 67 2006 960 967
    • (2006) Neurology , vol.67 , pp. 960-967
    • Wegner, C.1    Esiri, M.M.2    Chance, S.A.3
  • 79
    • 0036342788 scopus 로고    scopus 로고
    • Measurement of atrophy in multiple sclerosis; Pathological basis, methodological aspets and clinical relevance
    • D.H. Miller, F. Barhof, and J.A. Frank Measurement of atrophy in multiple sclerosis; pathological basis, methodological aspets and clinical relevance Brain 125 2002 1676 1695
    • (2002) Brain , vol.125 , pp. 1676-1695
    • Miller, D.H.1    Barhof, F.2    Frank, J.A.3
  • 80
    • 84869098364 scopus 로고    scopus 로고
    • Measurement and clinical effect of grey matter pathology in multiple sclerosis
    • J.J. Geurts, M. Calabrese, and E. Fisher Measurement and clinical effect of grey matter pathology in multiple sclerosis Lancet Neurol 2012
    • (2012) Lancet Neurol
    • Geurts, J.J.1    Calabrese, M.2    Fisher, E.3
  • 81
    • 2442423348 scopus 로고    scopus 로고
    • Early development of multiple asclerosis is associated with progressive gray matter atrophy in patients presenting with clinically isolated syndrome
    • C.M. Dalton, D.T. Chardt, and G.R. Davies Early development of multiple asclerosis is associated with progressive gray matter atrophy in patients presenting with clinically isolated syndrome Brain 127 2004 1101 1110
    • (2004) Brain , vol.127 , pp. 1101-1110
    • Dalton, C.M.1    Chardt, D.T.2    Davies, G.R.3
  • 82
    • 84890069253 scopus 로고    scopus 로고
    • Gray and white matter changes after 1 year after first clinical episode of multiple sclerosis
    • E. Raz, M. Cercignani, and E. Sbardella Gray and white matter changes after 1 year after first clinical episode of multiple sclerosis Radiology 2010 257448 257453
    • (2010) Radiology , pp. 257448-257453
    • Raz, E.1    Cercignani, M.2    Sbardella, E.3
  • 83
    • 84860455019 scopus 로고    scopus 로고
    • The neurologist's dilemma: MS is a grey matter disease that standard clinical and MRI measures cannot assess adequately: Yes
    • J.J. Geurts The neurologist's dilemma: MS is a grey matter disease that standard clinical and MRI measures cannot assess adequately: yes Mult Scler May 18 5 2012 559 560
    • (2012) Mult Scler , vol.18 MAY , Issue.5 , pp. 559-560
    • Geurts, J.J.1
  • 84
    • 84879774740 scopus 로고    scopus 로고
    • Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): Yes
    • Jul
    • R.A. Rudick, and E. Fisher Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): yes Mult Scler 19 8 2013 1003 1004 Jul
    • (2013) Mult Scler , vol.19 , Issue.8 , pp. 1003-1004
    • Rudick, R.A.1    Fisher, E.2
  • 85
    • 84879755259 scopus 로고    scopus 로고
    • Preventing brain atrophy should be the gold standard of effective theraphy in MS (after the first year of treatment): No
    • Jul
    • M. Filippi, and M. Rocca Preventing brain atrophy should be the gold standard of effective theraphy in MS (after the first year of treatment): no Mult Scler 19 8 2013 1005 1006 Jul
    • (2013) Mult Scler , vol.19 , Issue.8 , pp. 1005-1006
    • Filippi, M.1    Rocca, M.2


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