Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

Journal of Neurology Neurosurgery and Psychiatry

Volumn 70, Issue 3, 2001, Pages 311-317

  Cercignani, M ^a   Bozzali, M ^a   Iannucci, G ^a   Comi, G ^a   Filippi, M ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Grey matter diffusivity; Magnetisation transfer ratio; Multiple sclerosis; White matter diffusity

Indexed keywords

ACCELERATION; ADULT; ARTICLE; BRAIN SCINTISCANNING; BRAIN SLICE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; FEMALE; GRAY MATTER; HISTOGRAM; HUMAN; IMAGE ANALYSIS; MAGNETISM; MALE; MULTIPLE SCLEROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; WHITE MATTER;

ADULT; BRAIN; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS;

EID: 0035088438     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.70.3.311     Document Type: Article

References (40)

1. Filippi M, Horsfield MA, Ader HI, et al. Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities in monitoring the treatment of multiple sclerosis. Ann Neurol 1998;43:449-506.
2. Filippi M, Tortorella C, Bozzali M. Normal-appearing white matter changes in multiple sclerosis: the contribution of magnetic resonance techniques. Mult Scler 1999;5:273-82.
3. Kidd D, Barkhof F, McConnel R, et al. Cortical lesions in multiple sclerosis. Brain 1999;122:17-26.
4. Lexa FJ, Grossman RI, Rosenquist AC. MR of Wallerian degeneration in the feline visual system: characterization by magnetization transfer rate with histopathologic correlation. AJNR Am J Neuroradiol 1994;15:201-12.
5. van Waesberghe JHTM, Kamphorst W, De Groot CJA, et al. Axonal loss in MS lesions: MR insights into substrates of disability. Ann Neurol 1999;46:747-54.
6. Le Bihan D, Turner R, Pekar J, et al. Diffusion and perfusion imaging by gradient sensitization: design, strategy and significance. J Magn Reson Imaging 1991;1:7-8.
7. Basser PJ, Mattiello J, LeBihan D. MR diffusion tensor spectroscopy and imaging. Biophys J 1994;66:259-67.
8. Basser PJ, Pierpaoli C. Microstructural and physiological features of tissue elucidated by quantitative-diffusion-tensor MRI. J Magn Reson B 1996;111:209-19.
9. Pierpaoli C, Basser PJ. Towards a quantitative assessment of diffusion anisotropy. Magn Reson Med 1996;36:893-906.
10. Larsson HB, Thomsen C, Frederiksen J, et al. In vivo magnetic resonance diffusion measurement in the brain of patients with multiple sclerosis. Magn Reson Imaging 1992;10:7-12.
11. Christiansen P, Gideon P, Thomsen C, et al. Increased water self diffusion in chronic plaques and in apparently normal white matter in patients with multiple sclerosis. Acta Neurol Scand 1993;87:195-9.
12. Horsfield MA, Lai M, Webb SL, et al. Apparent diffusion coefficient in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance. Magn Reson Med 1996;36:393-400.
13. Droogan AG, Clark CA, Werring DJ, et al. Comparison of multiple sclerosis clinical subgroups using navigated spin echo diffusion-weighted imaging. Magn Reson Imaging 1999;17:653-61.
14. Werring DJ, Clark CA, Barker GJ, et al. Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis. Neurology 1999;52:1626-32.
15. Cercignani M, Iannucci G, Rocca MA, et al. Pathological damage in MS assessed by diffusion weighted and magnetization transfer MRI. Neurology 2000;54:1139-44.
16. Hajnal JV, Doran M, Hall AS. MR imaging of anisotropically restricted diffusion of water in the nervous system: technical, anatomic and pathologic considerations. J Comput Assist Tomogr 1991;5:1-18.
17. Lublin FD, Reingold SC, for the National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Defining the clinical course of multiple sclerosis: results of an international survey. Neurology 1996;46:907-11.
18. Kurtzke JF. Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52.
19. Jones DK, Horsfield MA, Simmons A. Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imaging. Magn Reson Med 1999;42:515-25.
20. Bito Y, Hirata S, Yamamoto E. Optimal gradient factors for ADC measurements. Proceedings of the Society of Magnetic Personnel: Third Scientific Meeting and Exhibition 1995;2: 913.
21. Miller DH, Barkhof F, Berry I, et al. Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines. J Neurol Neurosurg Psichiatry 1991;54:683-8.
22. Studholme C, Hill DLG, Hawkes DJ. Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures. Med Phys 1996;24:25-35.
23. Rovaris M, Filippi M, Calori G, et al. Intra-observer reproducibility in measuring new putative MR markers of demyelination and axonal loss in multiple sclerosis: a comparison with conventional T2-weighted images. J Neurol 1997; 244:266-70.
24. van Buchem MA, McGowan JC, Kolson DL, et al. Quantitative volumetric magnetization transfer analysis in multiple sclerosis: estimation of macroscopic and microscopic disease burden. Magn Reson Med 1996;36:632-9.
25. Filippi M. Magnetization transfer imaging to monitor the evolution of individual multiple sclerosis lesions. Neurology 1999;53(suppl 3):18-22.
26. Brownell B, Hughes JT. The distribution of plaques in the cerebrum in multiple sclerosis. J Neurol Neurosurg Psychiatry 1962;25:315-20.
27. Lumsden CE. The neuropathology of multiple sclerosis. In: Vinken PJ, Bruyn GW, eds. Handbook of clinical neurology: Vol 9. Amsterdam: North-Holland, 1970:217-309.
28. Filippi M, Yousry TA, Baratti C, et al. Quantitative assessment of MRI lesion load in multiple sclerosis: a comparison of conventional spin-echo with fast fluid-attenuated inversion recovery. Brain 1996;119:1349-55.
29. Gawne-Cain ML, O'Riordan JI, Thomson AJ, et al. Multiple sclerosis lesion detection in the brain. A comparison of fast fluid attenuated inversion recovery and conventional T2 weighted dual spin echo. Neurology 1997;49:364-70.
30. Miller DH, Barkhof F, Nauta JJ. Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 1993;116:1077-94.
31. Peyser JM, Edwards KR, Poser CM, et al. Cognitive function in patients with multiple sclerosis. Arch Neurol 1980;37:577-9.
32. Camp SJ, Stevenson VL, Thomson AJ, et al. Cognitive function in primary progressive and transitional progressive multiple sclerosis. A controlled study with MRI correlates. Brain 1999;122:1341-8.
33. Filippi M, Tortorella C, Rovaris M, et al. Changes in the normal-appearing brain tissue and cognitive impairment in multiple sclerosis. J Neurol Neurosurg Psichiatry 2000;68: 157-61.
34. Miki Y, Grossman RI, Udupa JK, et al. Isolated U-fiber involvement in MS. Preliminary observations. Neurology 1998;50:1301-6.
35. Fox NC, Jenkins R, Leary SM, et al. Progressive cerebral atrophy in MS. A serial study using registered, volumetric MRI. Neurology 2000;54:807-12.
36. Vavasour IM, Whittall KP, MacKay AL, et al. A comparison between magnetization transfer ratios and myelin water percentages in normals and multiple sclerosis patients. Magn Reson Med 1998;40:763-8.
37. Pike GB, De Stefano N, Narayanan S, et al. Combined magnetization transfer and proton spectroscopy imaging in the assessment of pathologic brain lesions in multiple sclerosis. AJNR Am J Neuroradiol 1999;20:829-37.
38. Filippi M, Campi A, Dousset V, et al. A magnetization transfer imaging study of normal appearing white matter in multiple sclerosis. Neurology 1995;45:478-82.
39. Loevner LA, Grossman RI, Cohen JA, et al. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization transfer measurements. Radiology 1995;96:511-15.
40. Tortorella C, Viti B, Bozzali M, et al. A magnetization transfer histogram study of normal-appearing brain tissue in MS. Neurology 2000;54:186-93.