Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis

American Journal of Neuroradiology

Volumn 33, Issue 7, 2012, Pages 1363-1368

  Hannoun, S ^a   Durand Dubief, F ^a,b   Confavreux, C ^b   Ibarrola, D ^c   Streichenberger, N ^b   Cotton, F ^a,b   Guttmann, C R G ^d   Sappey Marinier, Dominique ^a,c  

^a UNIVERSITÉ DE LYON   (France)

^b HÔPITAL NEUROLOGIQUE   (France)

^c CERMEP IMAGERIE DU VIVANT   (France)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; EXPANDED DISABILITY STATUS SCALE; FEMALE; FRACTIONAL ANISOTROPY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; MALE; MULTIPLE SCLEROSIS; NERVE CELL DEGENERATION; THALAMUS NUCLEUS; WHITE MATTER LESION;

ADULT; CAUDATE NUCLEUS; DIFFUSION MAGNETIC RESONANCE IMAGING; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MALE; MULTIPLE SCLEROSIS; NEURONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THALAMIC NUCLEI;

EID: 84865295471     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A2983     Document Type: Article

References (34)

1. Charcot J. Histologie de la sclérose en plaques [in French]. Gas Hop (Paris) 1868;141:554-58
2. Dawson JW. The histology of multiple sclerosis. Trans R Soc (Edinb) 1916;50:517-740
3. Brownell B, Hughes JT. The distribution of plaques in the cerebrum in multiple sclerosis. J Neurol Neurosurg Psychiatry 1962;25:315-20
4. Kidd D, Barkoff F, McConnell R, et al. Cortical lesions in multiple sclerosis. Brain 1999;122(Pt1):17-26
5. Miller DH, Barkhof F, Frank JA, et al. Measurement of atrophy in multiple sclerosis; pathological basis, methodological aspects and clinical relevance. Brain 2002;125:1676-95
6. Zivadinov R, Cox JL. Neuroimaging in multiple sclerosis. Int Rev Neurobiol 2007;79:449-74
7. Mesaros S, Rocca MA, Absinta M, et al. Evidence of thalamic grey matter loss in pediatric multiple sclerosis. Neurology 2008;70:1107-12
8. Tao G, Datta S, He R, et al. Deep grey matter atrophy in multiple sclerosis: A tensor based morphometry. J Neurol Sci 2009;282:39-46
9. Sepulcre J, Sastre-Garriga J, Cercignani M, et al. Regional grey matter atrophy in early primary progressive multiple sclerosis: a voxel-based morphometry study. Arch Neurol 2006;63:1175-80
10. Audoin B, Davies GR, Finisku L, et al. Localization of grey matter atrophy in early RRMS: a longitudinal study. J Neurol 2006;253:1495-501
11. Bermel RA, Bakshi R. The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol 2006;5:158-70
12. Khaleeli Z, Cercignani M, Audoin B, et al. Localized grey matter damage in early primary progressive multiple sclerosis contributes to disability. Neuro-image 2007;37:253-61
13. Rovaris M, Gass A, Bammer R, et al. Diffusion MRI in multiple sclerosis. Neurology 2005;65:1526-32
14. Ge Y, Law M, Grossman RI. Applications of diffusion tensor MR imaging in multiple sclerosis. Ann N Y Acad Sci 2005;1064:202-19
15. Hasan KM, Halphen C, Kamali A, et al. Caudate nuclei volume, diffusion tensor metrics, and T(2) relaxation in healthy adults and relapsing-remitting multiple sclerosis patients: implications for understanding grey matter degeneration. J Magn Reson Imaging 2009;29:70-77
16. Tovar-Moll F, Evangelou IE, Chiu AW, et al. Thalamic involvement and its impact on clinical disability in patients with multiple sclerosis: a diffusion tensor imaging study at 3T. AJNR Am J Neuroradiol 2009;30:1380-86
17. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis. Ann Neurol 2001;50:121-27
18. Fischl B, Salat DH, Busa E, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002;33:341-55
19. Fischl B, Salat DH, van der Kouwe AJ, et al. Sequence-independent segmentation of magnetic resonance images. Neuroimage 2004;23:S69-84
20. Smith SM, Jenkinson M, Woolrich MW, et al. Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage 2004;23:208-19
21. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp 2002;17:143-55
22. Souplet JC. Évaluation de l'atrophie et de la charge lésionnelle sur des séquences IRM de patients atteints de sclérose en plaques [in French]. PhD thesis, Université de Nice Sophia-Antipolis 2009
23. Hasan KM, Halphen C, Boska MD, et al. Diffusion tensor metrics, T2 relaxation, and volumetry of the natural aging human caudate nuclei in healthy young and middle-aged adults: possible implications for the neurobiology of human brain aging and disease. Magn Reson Med 2008;59:7-13
24. Hasbani MJ, Schlief ML, Fisher DA, et al. Dendritic spines lost during glutamate receptor activation reemerge at original sites of synaptic contact. J Neurosci 2001;21:2393-403
25. Trapp BD, Wujek JR, Criste GA, et al. Evidence for synaptic stripping by cortical microglia. Glia 2007;55:360-68
26. Kim IJ, Beck HN, Lein PJ, et al. Interferongammainduces retrograde dendritic retraction and inhibits synapse formation. J Neurosci 2002;22:4530-39
27. Mori S, Itoh R, Zhang J, et al. Diffusion tensor imaging of the developing mouse brain. Magn Reson Med 2001;46:18-23
28. Mukherjee P, Miller JH, Shimony JS, et al. Diffusion-tensor MR imaging of gray and white matter development during normal human brain maturation. AJNR Am J Neuroradiol 2002;23:1445-56
29. Zhang J, Richards LJ, Yarowsky P, et al. Three-dimensional anatomical characterization of the developing mouse brain by diffusion tensor microimaging. Neuroimage 2003;20:1639-48
30. Assaf Y, Basser PJ. Composite hindered and restricted model of diffusion (CHARMED) MR imaging of the human brain. Neuroimage 2005;27:48-58
31. Lumsden C. The neuropathology of multiple sclerosis. In: Vinken P, Bruyn G. Handbook of Clinical Neurology. Volume 9. Multiple Sclerosis and Other Demyelinating Diseases. New York: American Elsevier;1970:217-309
32. Wheeler-Kingshott C, Cercignani M. About "axial" and "radial" diffusivities. Magn Reson Med 2009;61:1255-60
33. Jones DK, Cercignani M. Twenty-five pitfalls in the analysis of diffusion MRI data. NMR Biomed 2010;23:803-20
34. Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 1996;36:893-906