-
1
-
-
0033512274
-
International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International Workshop
-
DOI 10.1002/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F
-
WA Wilson AE Gharavi T Koike, et al. 1999 International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop Arthritis Rheum 42 1309 1311 10.1002/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F 1:STN:280:DyaK1MzjtVSmsg%3D%3D 10403256 (Pubitemid 30265586)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.7
, pp. 1309-1311
-
-
Wilson, W.A.1
Gharavi, A.E.2
Koike, T.3
Lockshin, M.D.4
Ware Branch, D.5
Piette, J.-C.6
Brey, R.7
Derksen, R.8
Nigel Harris, E.9
Hughes, G.R.V.10
Triplett, D.A.11
Khamashta, M.A.12
-
2
-
-
0031787008
-
The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment
-
10.1177/096120339800700214 9814675
-
RA Asherson 1998 The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment Lupus 7 S55 S62 10.1177/096120339800700214 9814675
-
(1998)
Lupus
, vol.7
-
-
Asherson, R.A.1
-
3
-
-
0032833085
-
Isolation and characterization of two human monoclonal anti-phospholipid IgG from patients with autoimmune disease
-
DOI 10.1006/jaut.1999.0316
-
C von Landenberg KJ Lackner P von Landenberg, et al. 1999 Isolation and characterization of two human monoclonal anti-phospholipid IgG from patients with autoimmune disease J Autoimmun 13 215 223 10.1006/jaut.1999.0316 (Pubitemid 29436136)
-
(1999)
Journal of Autoimmunity
, vol.13
, Issue.2
, pp. 215-223
-
-
Von Landenberg, C.1
Lackner, K.J.2
Von Landenberg, P.3
Lang, B.4
Schmitz, G.5
-
4
-
-
33645962506
-
Antiphospholipid syndrome and tissue factor: A thrombotic couple
-
10.1191/0961203306lu2276rr 1:CAS:528:DC%2BD28XksVygsr4%3D 16634370
-
C Lopez-Pedrera P Buendia MA Aguirre, et al. 2006 Antiphospholipid syndrome and tissue factor: a thrombotic couple Lupus 15 161 166 10.1191/0961203306lu2276rr 1:CAS:528:DC%2BD28XksVygsr4%3D 16634370
-
(2006)
Lupus
, vol.15
, pp. 161-166
-
-
Lopez-Pedrera, C.1
Buendia, P.2
Aguirre, M.A.3
-
5
-
-
7244242660
-
Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: A pathway to targeted therapies
-
DOI 10.1016/j.thromres.2004.06.031, PII S0049384804003408
-
SS Pierangeli M Vega-Ostertag EN Harris 2004 Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies Thromb Res 114 467 476 10.1016/j.thromres.2004.06. 031 1:CAS:528:DC%2BD2cXovVKms7k%3D 15507280 (Pubitemid 39429425)
-
(2004)
Thrombosis Research
, vol.114
, Issue.SPEC. ISS.
, pp. 467-476
-
-
Pierangeli, S.S.1
Vega-Ostertag, M.2
Nigel Harris, E.3
-
6
-
-
7044254642
-
Mechanisms of autoantibody-induced monocyte tissue factor expression
-
DOI 10.1016/j.thromres.2004.06.012, PII S0049384804003202
-
AS Wolberg RA Roubey 2004 Mechanisms of autoantibody-induced monocyte tissue factor expression Thromb Res 114 391 396 10.1016/j.thromres.2004.06.012 1:CAS:528:DC%2BD2cXovVKmsrg%3D 15507269 (Pubitemid 39422571)
-
(2004)
Thrombosis Research
, vol.114
, Issue.SPEC. ISS.
, pp. 391-396
-
-
Wolberg, A.S.1
Roubey, R.A.S.2
-
7
-
-
31044449865
-
Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-κB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway
-
DOI 10.1002/art.21549
-
C Lopez-Pedrera P Buendia MJ Cuadrado, et al. 2006 Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway Arthritis Rheum 54 301 311 10.1002/art.21549 1:CAS:528:DC%2BD28XhsVensbo%3D 16385547 (Pubitemid 43122214)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.1
, pp. 301-311
-
-
Lopez-Pedrera, C.1
Buendia, P.2
Cuadrado, M.J.3
Siendones, E.4
Aguirre, M.A.5
Barbarroja, N.6
Montiel-Duarte, C.7
Torres, A.8
Khamashta, M.9
Velasco, F.10
-
8
-
-
28544449709
-
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
-
DOI 10.1084/jem.20051696
-
J Vollmer S Tluk C Schmitz, et al. 2005 Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8 J Exp Med 202 1575 1585 10.1084/jem.20051696 1:CAS:528: DC%2BD2MXhtlSqtLbJ 16330816 (Pubitemid 41746603)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.11
, pp. 1575-1585
-
-
Vollmer, J.1
Tluk, S.2
Schmitz, C.3
Hamm, S.4
Jurk, M.5
Forsbach, A.6
Akira, S.7
Kelly, K.M.8
Reeves, W.H.9
Bauer, S.10
Krieg, A.M.11
-
9
-
-
8844271818
-
Innate immunity in the antiphospholipid syndrome: Role of toll-like receptors in endothelial cell activation by antiphospholipid antibodies
-
DOI 10.1016/j.autrev.2004.07.007, PII S1568997204001065
-
PL Meroni E Raschi C Testoni, et al. 2004 Innate immunity in the antiphospholipid syndrome: role of toll-like receptors in endothelial cell activation by antiphospholipid antibodies Autoimmun Rev 3 510 515 10.1016/j.autrev.2004.07.007 1:CAS:528:DC%2BD2MXjs1yhtQ%3D%3D 15546799 (Pubitemid 39531243)
-
(2004)
Autoimmunity Reviews
, vol.3
, Issue.SPEC.ISS.
, pp. 510-515
-
-
Meroni, P.L.1
Raschi, E.2
Testoni, C.3
Parisio, A.4
Borghi, M.O.5
-
10
-
-
34250721890
-
Toll like Receptor 4 is involved in antiphospholipid- mediated thrombosis: In vivo studies
-
This article provides the first Evidence that TLRs are involved in the aPS pathophysiology
-
• Pierangeli SS, Vega-Ostertag ME, Raschi E, et al.: Toll like Receptor 4 is involved in antiphospholipid- mediated thrombosis: In vivo studies. Ann Rheum Dis 2007, 66:1327-1333. This article provides the first Evidence that TLRs are involved in the aPS pathophysiology.
-
Ann Rheum Dis 2007
, vol.66
, pp. 1327-1333
-
-
Pierangeli, S.S.1
Vega-Ostertag, M.E.2
Raschi, E.3
-
11
-
-
0036088492
-
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 [1]
-
DOI 10.1038/ni0602-499
-
M Jurk F Heil J Vollmer, et al. 2002 Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 Nat Immunol 3 499 10.1038/ni0602-499 1:CAS:528:DC%2BD38XjvFOmsLo%3D 12032557 (Pubitemid 34669818)
-
(2002)
Nature Immunology
, vol.3
, Issue.6
, pp. 499
-
-
Jurk, M.1
Heil, F.2
Vollmer, J.3
Schetter, C.4
Krieg, A.M.5
Wagner, H.6
Lipford, G.7
Bauer, S.8
-
12
-
-
0037528699
-
Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
-
DOI 10.1182/blood-2002-08-2349
-
E Raschi C Testoni D Bosisio, et al. 2003 Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies Blood 1 3495 3500 10.1182/blood-2002-08-2349 (Pubitemid 36857933)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3495-3500
-
-
Raschi, E.1
Testoni, C.2
Bosisio, D.3
Borghi, M.O.4
Koike, T.5
Mantovani, A.6
Meroni, P.L.7
-
13
-
-
26844467349
-
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
-
DOI 10.1084/jem.20050914
-
FJ Barrat T Meeker J Gregorio, et al. 2005 Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus J Exp Med 202 1131 1139 10.1084/jem.20050914 1:CAS:528:DC%2BD2MXhtFelu7vO 16230478 (Pubitemid 41464506)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.8
, pp. 1131-1139
-
-
Barrat, F.J.1
Meeker, T.2
Gregorio, J.3
Chan, J.H.4
Uematsu, S.5
Akira, S.6
Chang, B.7
Duramad, O.8
Coffman, R.L.9
-
14
-
-
33748472865
-
Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus
-
DOI 10.1016/j.immuni.2006.07.013, PII S1074761306003906
-
SR Christensen J Shupe K Nickerson, et al. 2006 Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus Immunity 25 417 428 10.1016/j.immuni.2006.07.013 1:CAS:528:DC%2BD28XhtVOjtLzN 16973389 (Pubitemid 44354217)
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, RichardA.5
Shlomchik, M.J.6
-
15
-
-
33645076274
-
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
-
10.1084/jem.20052438 1:CAS:528:DC%2BD28XjsVSqtb8%3D 16492804
-
M Ehlers H Fukuyama TL McGaha, et al. 2006 TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE J Exp Med 203 553 561 10.1084/jem.20052438 1:CAS:528:DC%2BD28XjsVSqtb8%3D 16492804
-
(2006)
J Exp Med
, vol.203
, pp. 553-561
-
-
Ehlers, M.1
Fukuyama, H.2
McGaha, T.L.3
-
16
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
DOI 10.1038/416603a
-
EA Leadbetter IR Rifkin AM Hohlbaum, et al. 2002 Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors Nature 416 603 607 10.1038/416603a 1:CAS:528:DC%2BD38XjtFahur8%3D 11948342 (Pubitemid 34406754)
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
17
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
S Akira S Uematsu O Takeuchi 2006 Pathogen recognition and innate immunity Cell 124 783 801 10.1016/j.cell.2006.02.015 1:CAS:528: DC%2BD28Xit1Kltb8%3D 16497588 (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
18
-
-
9644289387
-
Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?
-
DOI 10.1111/j.0105-2896.2004.00202.x
-
E Andreakos B Foxwell M Feldmann 2004 Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation? Immunol Rev 202 250 265 10.1111/j.0105-2896.2004. 00202.x 1:CAS:528:DC%2BD2MXhs1Ohug%3D%3D 15546398 (Pubitemid 39576917)
-
(2004)
Immunological Reviews
, vol.202
, pp. 250-265
-
-
Andreakos, E.1
Foxwell, B.2
Feldmann, M.3
-
19
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
DOI 10.1111/j.0105-2896.2005.00239.x
-
IR Rifkin EA Leadbetter L Busconi, et al. 2005 Toll-like receptors, endogenous ligands, and systemic autoimmune disease Immunol Rev 204 27 42 10.1111/j.0105-2896.2005.00239.x 1:CAS:528:DC%2BD2MXkslGnsrg%3D 15790348 (Pubitemid 40460491)
-
(2005)
Immunological Reviews
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
20
-
-
36049023453
-
The toll of too much TLR7
-
DOI 10.1016/j.immuni.2007.11.001, PII S1074761307004943
-
AM Krieg 2007 The toll of too much TLR7 Immunity 27 695 697 10.1016/j.immuni.2007.11.001 1:CAS:528:DC%2BD2sXhsVWjurrK 18031693 (Pubitemid 350102259)
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 695-697
-
-
Krieg, A.M.1
-
21
-
-
34547733912
-
Anti-beta2-glycoprotein i antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
-
This article provides the first direct connection of TLR activity with the aPL binding
-
• Sorice M, Longo A, Capozzi A, et al.: Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum 2007, 56:2687-2697. This article provides the first direct connection of TLR activity with the aPL binding.
-
Arthritis Rheum 2007
, vol.56
, pp. 2687-2697
-
-
Sorice, M.1
Longo, A.2
Capozzi, A.3
-
22
-
-
0031667314
-
New insights in glycosphingolipid function: Signaling domain, a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling
-
Hakomori S, Handa K, Iwabuchi K, et al.: New insights in glycosphingolipid function: signaling domain, a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling. Glycobiology 1998, 8:xi-xix.
-
Glycobiology 1998
, vol.8
-
-
Hakomori, S.1
Handa, K.2
Iwabuchi, K.3
-
23
-
-
3042797102
-
Endothelial cell activation by antiphospholipid antibodies
-
DOI 10.1016/j.clim.2004.02.015, PII S1521661604000634
-
PL Meroni E Raschi C Testoni MO Borghi 2004 Endothelial cell activation by antiphospholipid antibodies Clin Immunol 112 169 174 10.1016/j.clim.2004.02. 015 1:CAS:528:DC%2BD2cXls1eit7w%3D 15240160 (Pubitemid 38881482)
-
(2004)
Clinical Immunology
, vol.112
, Issue.2
, pp. 169-174
-
-
Meroni, P.L.1
Raschi, E.2
Testoni, C.3
Borghi, M.O.4
-
24
-
-
28444445251
-
2-glycoprotein I induces human dendritic cell maturation and promotes a T helper type 1 response
-
DOI 10.1182/blood-2005-03-1201
-
B Buttari E Profumo V Mattei, et al. 2005 Oxidized 2-glycoprotein I induces human dendritic cell maturation and promotes a T helper type 1 response Blood 106 3880 3887 10.1182/blood-2005-03-1201 1:CAS:528:DC%2BD2MXht12ktr7F 16099886 (Pubitemid 41739027)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3880-3887
-
-
Buttari, B.1
Profumo, E.2
Mattei, V.3
Siracusano, A.4
Ortona, E.5
Margutti, P.6
Salvati, B.7
Sorice, M.8
Rigano, R.9
-
25
-
-
0141445991
-
2-Glycoprotein I Increase Platelet Deposition to Collagen via Interaction with Phospholipids and the Apolipoprotein E Receptor 2′
-
DOI 10.1074/jbc.M212655200
-
BC Lutters RH Derksen WL Tekelenburg, et al. 2003 Dimers of 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2 J Biol Chem 278 33831 33838 10.1074/jbc.M212655200 1:CAS:528:DC%2BD3sXmvVCrtLY%3D 12807892 (Pubitemid 37553217)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 33831-33838
-
-
Lutters, B.C.H.1
Derksen, R.H.W.M.2
Tekelenburg, W.L.3
Lenting, P.J.4
Arnout, J.5
De Groot, P.G.6
-
26
-
-
0034685886
-
2-glycoprotein I to human endothelial cells is mediated by annexin II
-
DOI 10.1074/jbc.275.20.15541
-
K Ma R Simantov JC Zhang, et al. 2000 High affinity binding of 2-glycoprotein I to human endothelial cells is mediated by annexin II J Biol Chem 275 15541 15548 10.1074/jbc.275.20.15541 1:CAS:528:DC%2BD3cXjsFamsbY%3D 10809787 (Pubitemid 30337288)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.20
, pp. 15541-15548
-
-
Ma, K.1
Simantov, R.2
Zhang, J.-C.3
Silverstein, R.4
Hajjar, K.A.5
McCrae, K.R.6
-
27
-
-
0032526861
-
The human toll signaling pathway: Divergence of nuclear factor κb and jnk/sapk activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
-
DOI 10.1084/jem.187.12.2097
-
M Muzio G Natoli S Saccani, et al. 1998 The human Toll signaling pathway: divergence of NF-kB and JNK/SAPK activation upstream of TRAF6 J Exp Med 187 2097 3101 10.1084/jem.187.12.2097 1:CAS:528:DyaK1cXktVemsbk%3D 9625770 (Pubitemid 28285580)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.12
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
28
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
10.1016/S1097-2765(00)80136-7
-
R Medzhitov P Preston-Hurlburt E Kopp, et al. 1999 MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways Mol Cell 2 253 258 10.1016/S1097-2765(00)80136-7
-
(1999)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
-
29
-
-
59649101650
-
Annexin A2: Biology and relevance to the antiphospholipid syndrome
-
10.1177/0961203308095329 1:CAS:528:DC%2BD1cXhtlKru7%2FF 18827060
-
E Cockrell RG Espinola KR McCrae 2008 Annexin A2: biology and relevance to the antiphospholipid syndrome Lupus 17 943 951 10.1177/0961203308095329 1:CAS:528:DC%2BD1cXhtlKru7%2FF 18827060
-
(2008)
Lupus
, vol.17
, pp. 943-951
-
-
Cockrell, E.1
Espinola, R.G.2
McCrae, K.R.3
-
30
-
-
0036228886
-
Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients
-
DOI 10.1002/art.10187
-
R Cervera JC Piette J Font, et al. 2002 Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1, 000 patients Arthritis Rheum 46 1019 1027 10.1002/art.10187 11953980 (Pubitemid 34303815)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.4
, pp. 1019-1027
-
-
Cervera, R.1
Piette, J.-C.2
Font, J.3
Khamashta, M.A.4
Shoenfeld, Y.5
Camps, M.T.6
Jacobsen, S.7
Lakos, G.8
Tincani, A.9
Kontopoulou-Griva, I.10
Galeazzi, M.11
Meroni, P.L.12
Derksen, R.H.W.M.13
De Groot, P.G.14
Gromnica-Ihle, E.15
Baleva, M.16
Mosca, M.17
Bombardieri, S.18
Houssiau, F.19
Gris, J.-C.20
Quere, I.21
Hachulla, E.22
Vasconcelos, C.23
Roch, B.24
Fernandez-Nebro, A.25
Boffa, M.-C.26
Hughes, G.R.V.27
Ingelmo, M.28
more..
-
31
-
-
70449509134
-
Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
-
10.1182/blood-2008-11-188698 1:CAS:528:DC%2BD1MXht12qur3O 19628708
-
Z Romay-Penabad MG Montiel-Manzano T Shilagard, et al. 2009 Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo Blood 114 3074 3083 10.1182/blood-2008-11-188698 1:CAS:528: DC%2BD1MXht12qur3O 19628708
-
(2009)
Blood
, vol.114
, pp. 3074-3083
-
-
Romay-Penabad, Z.1
Montiel-Manzano, M.G.2
Shilagard, T.3
-
32
-
-
0036196287
-
Bacterial induction of autoantibodies to 2-glycoprotein-1 accounts for the infectious etiology of antiphospholipid syndrome
-
1:CAS:528:DC%2BD38Xit1Gnsro%3D 11901188
-
M Blank I Krause M Fridkin, et al. 2002 Bacterial induction of autoantibodies to 2-glycoprotein-1 accounts for the infectious etiology of antiphospholipid syndrome J Clin Invest 109 797 804 1:CAS:528: DC%2BD38Xit1Gnsro%3D 11901188
-
(2002)
J Clin Invest
, vol.109
, pp. 797-804
-
-
Blank, M.1
Krause, I.2
Fridkin, M.3
-
33
-
-
77949262403
-
Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8
-
May 18 (Epub ahead of print)
-
Döring Y, Hurst J, Lorenz M, et al.: Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8. Immunobiology 2009 May 18 (Epub ahead of print).
-
Immunobiology 2009
-
-
Döring, Y.H.1
-
34
-
-
33846000646
-
The functional effects of physical interactions among toll-like receptors 7, 8, and 9
-
DOI 10.1074/jbc.M605311200
-
J Wang Y Shao TA Bennett, et al. 2006 The functional effects of physical interactions among Toll-like receptors 7, 8, and 9 J Biol Chem 281 37427 37434 10.1074/jbc.M605311200 1:CAS:528:DC%2BD28Xht1KitrjI 17040905 (Pubitemid 46042046)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 37427-37434
-
-
Wang, J.1
Shao, Y.2
Bennett, T.A.3
Shankar, R.A.4
Wightman, P.D.5
Reddy, L.G.6
-
35
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
1:CAS:528:DC%2BD38Xjt12jt7k%3D 11970999
-
V Hornung S Rothenfusser S Britsch, et al. 2002 Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides J Immunol 168 4531 4537 1:CAS:528:DC%2BD38Xjt12jt7k%3D 11970999
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
36
-
-
0141958218
-
Expression and function of Toll-like receptors in eosinophils: Activation by Toll-like receptor 7 ligand
-
1:CAS:528:DC%2BD3sXnvVOks7c%3D 14530316
-
H Nagase S Okugawa Y Ota, et al. 2003 Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand J Immunol 171 3977 3982 1:CAS:528:DC%2BD3sXnvVOks7c%3D 14530316
-
(2003)
J Immunol
, vol.171
, pp. 3977-3982
-
-
Nagase, H.1
Okugawa, S.2
Ota, Y.3
-
37
-
-
12444341806
-
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
-
1:CAS:528:DC%2BD2MXlsFyhsQ%3D%3D 15661881
-
KB Gorden KS Gorski SJ Gibson, et al. 2005 Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8 J Immunol 174 1259 1268 1:CAS:528:DC%2BD2MXlsFyhsQ%3D%3D 15661881
-
(2005)
J Immunol
, vol.174
, pp. 1259-1268
-
-
Gorden, K.B.1
Gorski, K.S.2
Gibson, S.J.3
-
38
-
-
33744481250
-
Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
-
DOI 10.1182/blood-2005-07-2636
-
G Cesarman-Maus NP Rios-Luna AB Deora, et al. 2006 Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome Blood 107 4375 4382 10.1182/blood-2005-07-2636 1:CAS:528:DC%2BD28Xlt1CgsLc%3D 16493010 (Pubitemid 43801363)
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4375-4382
-
-
Cesarman-Maus, G.1
Rios-Luna, N.P.2
Deora, A.B.3
Huang, B.4
Villa, R.5
Cravioto, M.D.C.6
Alarcon-Segovia, D.7
Sanchez-Guerrero, J.8
Hajjar, K.A.9
-
39
-
-
33745617886
-
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
-
DOI 10.1073/pnas.0603912103
-
S Subramanian K Tus QZ Li, et al. 2006 A Tlr7 translocation accelerates systemic autoimmunity in murine lupus Proc Natl Acad Sci USA 103 9970 9975 10.1073/pnas.0603912103 1:CAS:528:DC%2BD28XmvVajtbY%3D 16777955 (Pubitemid 43993607)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.26
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.-Z.3
Wang, A.4
Tian, X.-H.5
Zhou, J.6
Liang, C.7
Bartov, G.8
McDaniel, L.D.9
Zhou, X.J.10
Schultz, R.A.11
Wakeland, E.K.12
-
40
-
-
10844288801
-
TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss
-
1:CAS:528:DC%2BD2cXhtFaiu77P 15611274
-
J Berman G Girardi JE Salmon 2005 TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss J Immunol 174 485 490 1:CAS:528:DC%2BD2cXhtFaiu77P 15611274
-
(2005)
J Immunol
, vol.174
, pp. 485-490
-
-
Berman, J.1
Girardi, G.2
Salmon, J.E.3
-
41
-
-
14744275911
-
Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprosy related antiphospholipid antibodies
-
DOI 10.1191/0961203305lu2048oa
-
RR Forastiero ME Martinuzzo GF de Larranaga 2005 Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprosy related antiphospholipid antibodies Lupus 14 129 136 10.1191/0961203305lu2048oa 1:CAS:528:DC%2BD2MXis1Smtb8%3D 15751817 (Pubitemid 40327663)
-
(2005)
Lupus
, vol.14
, Issue.2
, pp. 129-136
-
-
Forastiero, R.R.1
Martinuzzo, M.E.2
De Larranaga, G.F.3
-
42
-
-
11144349087
-
Upregulation of TNF-α-induced ICAM-1 surface expression by adenylate cyclase-dependent pathway in human endothelial cells
-
DOI 10.1002/jcp.20134
-
D Bernot F Peiretti M Canault, et al. 2005 Upregulation of TNF-alpha-induced ICAM-1 surface expression by adenylate cyclase-dependent pathway in human endothelial cells J Cell Physiol 202 434 441 10.1002/jcp.20134 1:CAS:528:DC%2BD2MXot1ajuw%3D%3D 15389590 (Pubitemid 40041313)
-
(2005)
Journal of Cellular Physiology
, vol.202
, Issue.2
, pp. 434-441
-
-
Bernot, D.1
Peiretti, F.2
Canault, M.3
Juhan-Vague, I.4
Nalbone, G.5
-
43
-
-
33846243719
-
Current concepts on the pathogenesis of the antiphospholipid syndrome
-
DOI 10.1182/blood-2006-04-001206
-
B Giannakopoulos F Passam S Rahgozar SA Krilis 2007 Current concepts on the pathogenesis of the antiphospholipid syndrome Blood 109 422 430 10.1182/blood-2006-04-001206 1:CAS:528:DC%2BD2sXivVykur4%3D 16985176 (Pubitemid 46105935)
-
(2007)
Blood
, vol.109
, Issue.2
, pp. 422-430
-
-
Giannakopoulos, B.1
Passam, F.2
Rahgozar, S.3
Krilis, S.A.4
-
44
-
-
3042797102
-
Endothelial cell activation by antiphospholipid antibodies
-
DOI 10.1016/j.clim.2004.02.015, PII S1521661604000634
-
PL Meroni E Raschi C Testoni MO Borghi 2004 Endothelial cell activation by antiphospholipid antibodies Clin Immunol 112 169 174 10.1016/j.clim.2004.02. 015 1:CAS:528:DC%2BD2cXls1eit7w%3D 15240160 (Pubitemid 38881482)
-
(2004)
Clinical Immunology
, vol.112
, Issue.2
, pp. 169-174
-
-
Meroni, P.L.1
Raschi, E.2
Testoni, C.3
Borghi, M.O.4
-
45
-
-
24744467812
-
Synergistic induction of tissue factor by coagulation factor Xa and TNF: Evidence for involvement of negative regulatory signaling cascades
-
DOI 10.1073/pnas.0504526102
-
A Hezi-Yamit PW Wong N Bien-Ly, et al. 2005 Synergistic induction of tissue factor by coagulation factor Xa and TNF: evidence for involvement of negative regulatory signaling cascades Proc Natl Acad Sci U S A 102 12077 12082 10.1073/pnas.0504526102 1:CAS:528:DC%2BD2MXps1yru7k%3D 16105945 (Pubitemid 41291131)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.34
, pp. 12077-12082
-
-
Hezi-Yamit, A.1
Wong, P.W.2
Bien-Ly, N.3
Komuves, L.G.4
Prasad, K.S.S.5
Phillips, D.R.6
Sinha, U.7
-
46
-
-
0000555820
-
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: Characterization and comparison with the actions of interleukin 1
-
10.1073/pnas.83.12.4533 1:CAS:528:DyaL28XksVSru7g%3D 3487091
-
MP Bevilacqua JS Pober GR Majeau, et al. 1986 Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1 Proc Natl Acad Sci U S A 83 4533 4537 10.1073/pnas.83.12.4533 1:CAS:528:DyaL28XksVSru7g%3D 3487091
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 4533-4537
-
-
Bevilacqua, M.P.1
Pober, J.S.2
Majeau, G.R.3
-
47
-
-
33751511117
-
Gene Expression Analysis in Blood Cells in Response to Unmodified and 2′-Modified siRNAs Reveals TLR-dependent and Independent Effects
-
DOI 10.1016/j.jmb.2006.09.034, PII S0022283606012253
-
L Cekaite G Furset E Hovig M Sioud 2007 Gene expression analysis in blood cells in response to unmodified and 2-modified siRNAs reveals TLR-dependent and independent effects J Mol Biol 365 90 108 10.1016/j.jmb.2006.09.034 1:CAS:528:DC%2BD28Xht1KnsrnJ 17054988 (Pubitemid 44830036)
-
(2007)
Journal of Molecular Biology
, vol.365
, Issue.1
, pp. 90-108
-
-
Cekaite, L.1
Furset, G.2
Hovig, E.3
Sioud, M.4
-
48
-
-
20444372982
-
The antiphospholipid antibody syndrome research in patients with retinal venous occlusion
-
DOI 10.1016/j.arcmed.2005.03.032, PII S0188440905001062
-
F Ilhan U Celiker A Godekmerdan E Kan 2005 The antiphospholipid antibody syndrome research in patients with retinal venous occlusion Arch Med Res 36 372 375 10.1016/j.arcmed.2005.03.032 1:CAS:528:DC%2BD2MXltFaktbk%3D 15950077 (Pubitemid 40798391)
-
(2005)
Archives of Medical Research
, vol.36
, Issue.4
, pp. 372-375
-
-
Ilhan, F.1
Celiker, U.2
Godekmerdan, A.3
Kan, E.4
-
49
-
-
67650067301
-
TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells
-
This article discusses the first presentation of a new signaling cascade downstream of TLR7 and TLR8 toward IL-1β and Caspase-1
-
• Hurst J, Prinz N, Lorenz M, et al.: TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells. Immunobiology 2009, 214:683-691. This article discusses the first presentation of a new signaling cascade downstream of TLR7 and TLR8 toward IL-1β and Caspase-1.
-
Immunobiology 2009
, vol.214
, pp. 683-691
-
-
Hurst, J.1
Prinz, N.2
Lorenz, M.3
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