ROS and RNS induced apoptosis through p53 and iNOS mediated pathway by a dibasic hydroxamic acid molecule in leukemia cells

European Journal of Pharmaceutical Sciences

Volumn 52, Issue 1, 2014, Pages 146-164

  Banerjee, Kaushik ^a   Ganguly, Avishek ^a   Chakraborty, Paramita ^a   Sarkar, Avijit ^b   Singh, Suryabhan ^c   Chatterjee, Mitali ^b   Bhattacharya, Subrato ^c   Choudhuri, Soumitra Kumar ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b Institute of Medical Education and Research   (India)

^c BANARAS HINDU UNIVERSITY   (India)

Author keywords

Apoptosis; HDAC3; iNOS; p53; Reactive nitrogen species; Reactive oxygen species

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DOXORUBICIN; GLUTATHIONE; HISTONE DEACETYLASE 3; HYDROXAMIC ACID DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; OXAYL BIS N PHENYL HYDROXAMIC ACID; PROTEIN P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CRYSTAL STRUCTURE; DOWN REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; PHARMACOPHORE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

APOPTOSIS; HDAC3; INOS; P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZENEACETAMIDES; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; GLUTATHIONE; HUMANS; HYDROXAMIC ACIDS; LEUKEMIA; LEUKOCYTES, MONONUCLEAR; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXALATES; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84889679570     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.11.009     Document Type: Article

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