Mechanisms involved in the pro- and anti-apoptotic role of NO in human leukemia

Leukemia

Volumn 14, Issue 9, 2000, Pages 1685-1694

  Kolb, J P ^a  

^a INSTITUT CURIE   (France)

Author keywords

Apoptosis; Bcl 2; Caspases; Leukemia; Mitochondrial potential; Nitric oxide

Indexed keywords

CASPASE; CERAMIDE; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYSTEINE; DNA; HEAT SHOCK PROTEIN 70; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; B CELL LEUKEMIA; B LYMPHOCYTE; CELL LINEAGE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; DRUG RESEARCH; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVIEW; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 0033828545     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401896     Document Type: Review

References (95)

1. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
2. Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
3. Nitric oxide and apoptosis: Another paradigm for the double-edged role of nitric oxide
4. Nitric oxide: Inducer or suppressor of apoptosis?
5. Apoptotic cell death and nitric oxide: Activating and antagonistic transducing pathways
6. Nitric oxide and its role in apoptosis
7. Nitric oxide synthase induces macrophage death by apoptosis
8. Nitric oxide-mediated apoptosis in murine peritoneal macrophages
9. Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric oxide
10. Nitric oxide modulation of human leukemia cell differentiation and gene expression
11. Nitric oxide modulation of the growth and differentiation of freshly isolated acute non-lymphocytic leukemia cells
12. Differential effects of nitric oxide on erythroid and myeloid colony growth from CD34+ human bone marrow cells
13. Esterase-sensitive nitric oxide donors of the diazeniumdiolate family: In vitro antileukemic activity
14. Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen
15. Role of nitric oxide in the anti-tumoral effect of retinoic acid and 1,25-dihydroxyvitamin D3 on human promonocytic leukemic cells
16. Leukemia cell differentiation: Cellular and molecular interactions of retinoids and vitamin D
17. Mode of cytostatic action of mesoionic oxatriazole nitric oxide donors in proliferating human hematopoietic cells
18. Potentiation of the activity of nitric oxide by the protein kinase C activator phorbol ester in human myeloid leukemic HL-60 cells: Association with enhanced fragmentation of mature genomic DNA
19. Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells
20. Cyclic adenosine monophosphate inhibits nitric oxide-induced apoptosis in human leukemic HL-60 cells
21. Schedule and concentration-dependent induction of apoptosis in leukemia cells by nitric oxide
22. Geranylgeranylacetone induces apoptosis in HL-60 cells
23. Molecular mechanisms of apoptosis in HL-60 cells induced by a nitric oxide-releasing compound
24. Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu,Zn-superoxide dismutase and catalase
25. Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3
26. U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation
27. Nitric oxide in apoptotic versus necrotic RAW 264.7 macrophage cell death: The role of NO-donor exposure, NAD content, and p53 accumulation
28. Protease activation during nitric oxide-induced apoptosis: Comparison between poly(ADP-ribose) polymerase and U1-70kDa cleavage
29. Peroxynitrite-induced apoptosis in HL-60 cells
30. Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease
31. Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells
32. Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells
33. Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release
34. Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to gamma-interferon and tumor necrosis factor-alpha
35. Divergent effect of taxol on proliferation, apoptosis and nitric oxide production in MHH225 CD34 positive and U937 CD34 negative human leukaemia cells
36. Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis
37. Nitric oxide dissociates lipid oxidation from apoptosis and phosphatidylserine externalization during oxidative stress
38. Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
39. In vivo ubiquitination and proteasome-mediated degradation of p53
40. Mitochondrial control of apoptosis
41. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition
42. Nitric oxide induces tyrosine nitration and release of cytochrome c preceding an increase of mitochondrial transmembrane potential in macrophages
43. Nitric oxide synthase activity in mitochondria
44. Production of nitric oxide by mitochondria
45. Mitochondrial nitric oxide synthase regulates mitochondrial matrix pH
46. Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation
47. Nitrite reductase activity is a novel function of mammalian mitochondria
48. Quenching of the tyrosyl free radical of ribonucleotide reductase by nitric oxide. Relationship to cytostasis induced in tumor cells by cytotoxic macrophages
49. Nitric oxide activation of poly(ADP-ribose) synthase in neurotoxicity
50. Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerbral ischemia
51. p53 expression in nitric-oxide induced apoptosis
52. P53, the cellular gatekeeper for growth and division
53. A model for p53 induced apoptosis
54. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
55. Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice
56. p53 inhibits hypoxia-inducible factor-stimulated transcription
57. p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells
58. Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis
59. Activation of the cell death program by nitric oxide involves inhibition of the proteasome
60. Proteasome-dependent regulation of p21WAF1/CIP1 expression
61. Nitric oxide (NO): An effector of apoptosis
62. Nitric oxide induced poly(ADP-ribose) polymerase cleavage in RAW 264.7 macrophage apoptosis is blocked by Bcl-2
63. NO: An inhibitor of cell death
64. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels
65. 6-Mercaptopurine decreases the Bcl-2/Bax ratio and induces apoptosis in activated splenic B lymphocytes
66. Nitric oxide produced by human lymphocytes inhibit apoptosis and Epstein-Barr virus reactivation
67. Nitric oxide production by human monocytes. Evidence for a role of CD23
68. B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity
69. Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells
70. Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia
71. Detection of inducible nitric oxide synthase (NOS2) mRNA, antigen and enzyme activity in leukemia cells from patients with CLL
72. The hairy cell leukemia cell line Eskol spontaneously synthesizes tumor necrosis factor-alpha and nitric oxide
73. Expression of a functional inducible nitric oxide synthase in hairy cell leukemia and ESKOL cell line
74. Contribution of nitric oxide to the apoptotic process in human B cell chronic lymphocytic leukaemia
75. Detection of inducible nitric oxide synthase (iNOS) mRNA by RT-PCR in ATL patients and HTLV-I infected cell lines: Clinical features and apoptosis by NOS inhibitor
76. Expression of human inducible nitric oxide synthase gene in T-cell lines infected with human T-cell leukemia virus type-I and primary adult T-cell leukemia cells
77. Up-regulation of iNOS mRNA expression and increased production of NO in human monoblast cell line, U937 transfected by HTLV-I tax gene
78. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation
79. Effects of redox-related congeners of NO on apoptosis and caspase-3 activity
80. Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide
81. Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis
82. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms
83. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultures hepatocytes
84. Nitric oxide inhibits caspase-3 by S-Nitrosation in vivo
85. Mass spectrometry analysis of nitric oxide-modified caspase-3
86. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases
87. Nitric oxide inhibits Fas-induced apoptosis
88. Nitric oxide inhibits APO-1/Fas-mediated cell death
89. Fas-induced caspase denitrosylation
90. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
91. The proto-oncogene Bcl-2 and its role in regulating apoptosis
92. Nitric oxide fully protects against UVA-induced apoptosis in tight correlation with Bcl-2 up-regulation
93. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression
94. Autocrine nitric oxide modulates CD95-induced apoptosis in gammadelta T lymphocytes