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Volumn 32, Issue 12, 2011, Pages 1840-1848

Heme oxygenase-1: A molecular brake on hepatocellular carcinoma cell migration

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; HEME OXYGENASE 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 81855183855     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr225     Document Type: Article
Times cited : (49)

References (45)
  • 1
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • Jemal,A. et al. (2011) Global cancer statistics. CA Cancer J. Clin., 61, 69-90.
    • (2011) CA Cancer J. Clin. , vol.61 , pp. 69-90
    • Jemal, A.1
  • 2
    • 81855216066 scopus 로고    scopus 로고
    • Key questions in metastasis: new insights in molecular pathways and therapeutic implications
    • Gueron,G. et al. (2011) Key questions in metastasis: new insights in molecular pathways and therapeutic implications. Curr. Pharm. Biotechnol.
    • (2011) Curr. Pharm. Biotechnol
    • Gueron, G.1
  • 3
    • 2942530875 scopus 로고    scopus 로고
    • Cell cycle arrest and modulation of HO-1 expression induced by acetyl salicylic acid in hepatocarcinogenesis
    • Sacca,P. et al. (2004) Cell cycle arrest and modulation of HO-1 expression induced by acetyl salicylic acid in hepatocarcinogenesis. Int. J. Biochem. Cell Biol., 36, 1945-1953.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1945-1953
    • Sacca, P.1
  • 4
    • 0033992256 scopus 로고    scopus 로고
    • Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression
    • Liu,N. et al. (2000) Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression. Gene, 241, 175-183.
    • (2000) Gene , vol.241 , pp. 175-183
    • Liu, N.1
  • 5
    • 2942555358 scopus 로고    scopus 로고
    • Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries
    • Takahashi,T. et al. (2004) Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. Curr. Med. Chem., 11, 1545-1561.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1545-1561
    • Takahashi, T.1
  • 6
    • 77949525185 scopus 로고    scopus 로고
    • Mechanisms of cell protection by heme oxygenase-1
    • Gozzelino,R. et al. (2010) Mechanisms of cell protection by heme oxygenase-1. Annu. Rev. Pharmacol. Toxicol., 50, 323-354.
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , pp. 323-354
    • Gozzelino, R.1
  • 7
    • 35848942608 scopus 로고    scopus 로고
    • Heme oxygenase-1 in tumors: is it a false friend?
    • Jozkowicz,A. et al. (2007) Heme oxygenase-1 in tumors: is it a false friend? Antioxid. Redox Signal., 9, 2099-2117.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 2099-2117
    • Jozkowicz, A.1
  • 8
    • 35848932314 scopus 로고    scopus 로고
    • Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice
    • Was,H. et al. (2006) Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice. Am. J. Pathol., 169, 2181-2198.
    • (2006) Am. J. Pathol. , vol.169 , pp. 2181-2198
    • Was, H.1
  • 9
    • 49849103925 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9
    • Lin,C.W. et al. (2008) Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9. Mol. Cancer Ther., 7, 1195-1206.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 1195-1206
    • Lin, C.W.1
  • 10
    • 64349099334 scopus 로고    scopus 로고
    • 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS
    • Kim,D.H. et al. (2009) 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. Carcinogenesis, 30, 645-654.
    • (2009) Carcinogenesis , vol.30 , pp. 645-654
    • Kim, D.H.1
  • 11
    • 72449123797 scopus 로고    scopus 로고
    • Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells
    • Gueron,G. et al. (2009) Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells. Mol. Cancer Res., 7, 1745-1755.
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1745-1755
    • Gueron, G.1
  • 12
    • 70350221874 scopus 로고    scopus 로고
    • A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer
    • Alaoui-Jamali,M.A. et al. (2009) A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res., 69, 8017-8024.
    • (2009) Cancer Res. , vol.69 , pp. 8017-8024
    • Alaoui-Jamali, M.A.1
  • 13
    • 77957590701 scopus 로고    scopus 로고
    • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases
    • Liu,P.L. et al. (2010) Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases. Mol. Nutr. Food Res., 54 (Suppl 2), S196-S204.
    • (2010) Mol. Nutr. Food Res. , vol.54 , Issue.SUPPL. 2
    • Liu, P.L.1
  • 14
    • 0042388388 scopus 로고    scopus 로고
    • Carbon monoxide-a "new" gaseous modulator of gene expression
    • Dulak,J. et al. (2003) Carbon monoxide-a "new" gaseous modulator of gene expression. Acta Biochim. Pol., 50, 31-47.
    • (2003) Acta Biochim. Pol. , vol.50 , pp. 31-47
    • Dulak, J.1
  • 15
    • 35848954977 scopus 로고    scopus 로고
    • Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target
    • Joung,E.J. et al. (2007) Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid. Redox Signal., 9, 2087-2098.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 2087-2098
    • Joung, E.J.1
  • 16
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee,T.S. et al. (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med., 8, 240-246.
    • (2002) Nat. Med. , vol.8 , pp. 240-246
    • Lee, T.S.1
  • 17
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill,F. et al. (2001) Inflammation and cancer: back to Virchow? Lancet, 357, 539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1
  • 18
    • 38849106118 scopus 로고    scopus 로고
    • Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma
    • Porta,C. et al. (2008) Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma. Ann. Oncol., 19, 353-358.
    • (2008) Ann. Oncol. , vol.19 , pp. 353-358
    • Porta, C.1
  • 19
    • 0037029701 scopus 로고    scopus 로고
    • Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma
    • Yoshida,N. et al. (2002) Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma. Br.J.Cancer, 86, 1396-1400.
    • (2002) Br. J. Cancer , vol.86 , pp. 1396-1400
    • Yoshida, N.1
  • 20
    • 0033017066 scopus 로고    scopus 로고
    • Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer
    • Chen,Z. et al. (1999) Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer. Clin. Cancer Res., 5, 1369-1379.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1369-1379
    • Chen, Z.1
  • 21
    • 0042209597 scopus 로고    scopus 로고
    • Serum interleukin-6 levels reflect the disease status of colorectal cancer
    • Chung,Y.C. et al. (2003) Serum interleukin-6 levels reflect the disease status of colorectal cancer. J. Surg. Oncol., 83, 222-226.
    • (2003) J. Surg. Oncol. , vol.83 , pp. 222-226
    • Chung, Y.C.1
  • 22
    • 77958113395 scopus 로고    scopus 로고
    • Correlation of Nrf2, HO-1, and MRP3 in gallbladder cancer and their relationships to clinicopathologic features and survival
    • Wang,J. et al. (2011) Correlation of Nrf2, HO-1, and MRP3 in gallbladder cancer and their relationships to clinicopathologic features and survival. J. Surg. Res., 164, e99-105.
    • (2011) J. Surg. Res. , vol.164
    • Wang, J.1
  • 23
    • 78650145260 scopus 로고    scopus 로고
    • The effect of the Gly139His, Gly143His, and Ser1 42His mouse heme oxygenase-1 mutants on the HO reaction in vivo and in vitro
    • Zhou,L. et al. (2010) The effect of the Gly139His, Gly143His, and Ser1 42His mouse heme oxygenase-1 mutants on the HO reaction in vivo and in vitro. Anat. Rec. (Hoboken), 294, 112-118.
    • (2010) Anat. Rec. (Hoboken) , vol.294 , pp. 112-118
    • Zhou, L.1
  • 24
    • 73149100826 scopus 로고    scopus 로고
    • Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression
    • Maeda,S. et al. (2009) Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression. Hepatology, 50, 1851-1860.
    • (2009) Hepatology , vol.50 , pp. 1851-1860
    • Maeda, S.1
  • 25
    • 62449325220 scopus 로고    scopus 로고
    • Heme oxygenase-1 induction in macrophages by a hemoglobin-based oxygen carrier reduces endotoxin-stimulated cytokine secretion
    • Roach,J.P. et al. (2009) Heme oxygenase-1 induction in macrophages by a hemoglobin-based oxygen carrier reduces endotoxin-stimulated cytokine secretion. Shock, 31, 251-257.
    • (2009) Shock , vol.31 , pp. 251-257
    • Roach, J.P.1
  • 26
    • 0037622140 scopus 로고    scopus 로고
    • Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities
    • Motterlini,R. et al. (2002) Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ. Res., 90, E17-E24.
    • (2002) Circ. Res. , vol.90
    • Motterlini, R.1
  • 27
    • 23044459608 scopus 로고    scopus 로고
    • Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages
    • Sawle,P. et al. (2005) Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages. Br. J. Pharmacol., 145, 800-810.
    • (2005) Br. J. Pharmacol. , vol.145 , pp. 800-810
    • Sawle, P.1
  • 28
    • 40149102484 scopus 로고    scopus 로고
    • Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages
    • Hong,H.Y. et al. (2008) Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. FEBS Lett., 582, 861-868.
    • (2008) FEBS Lett. , vol.582 , pp. 861-868
    • Hong, H.Y.1
  • 29
    • 0142214848 scopus 로고    scopus 로고
    • Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer
    • Sunamura,M. et al. (2003) Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer. Angiogenesis, 6, 15-24.
    • (2003) Angiogenesis , vol.6 , pp. 15-24
    • Sunamura, M.1
  • 30
    • 49249123275 scopus 로고    scopus 로고
    • Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients
    • Vashist,Y.K. et al. (2008) Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients. J. Oral Pathol. Med., 37, 480-484.
    • (2008) J. Oral Pathol. Med. , vol.37 , pp. 480-484
    • Vashist, Y.K.1
  • 31
    • 79952486696 scopus 로고    scopus 로고
    • Heme oxygenase-1 promoter polymorphism is a predictor of disease relapse in pancreatic neuroendocrine tumors
    • Vashist,Y.K. et al. (2010) Heme oxygenase-1 promoter polymorphism is a predictor of disease relapse in pancreatic neuroendocrine tumors. J. Surg. Res., 166, e121-e127.
    • (2010) J. Surg. Res. , vol.166
    • Vashist, Y.K.1
  • 32
    • 40049088602 scopus 로고    scopus 로고
    • The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages
    • Allavena,P. et al. (2008) The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit. Rev. Oncol. Hematol., 66, 1-9.
    • (2008) Crit. Rev. Oncol. Hematol. , vol.66 , pp. 1-9
    • Allavena, P.1
  • 33
    • 38049093090 scopus 로고    scopus 로고
    • Inflammation, HCC and sex: IL-6 in the centre of the triangle
    • Prieto,J. (2008) Inflammation, HCC and sex: IL-6 in the centre of the triangle. J. Hepatol., 48, 380-381.
    • (2008) J. Hepatol. , vol.48 , pp. 380-381
    • Prieto, J.1
  • 34
    • 65649111667 scopus 로고    scopus 로고
    • High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B
    • Wong,V.W. et al. (2009) High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B. Int. J. Cancer, 124, 2766-2770.
    • (2009) Int. J. Cancer , vol.124 , pp. 2766-2770
    • Wong, V.W.1
  • 35
    • 0029988916 scopus 로고    scopus 로고
    • Interleukin-6 production by rat hepatocellular carcinoma cells is associated with metastatic potential but not with tumorigenicity
    • Reichner,J.S. et al. (1996) Interleukin-6 production by rat hepatocellular carcinoma cells is associated with metastatic potential but not with tumorigenicity. Arch. Surg., 131, 360-365.
    • (1996) Arch. Surg. , vol.131 , pp. 360-365
    • Reichner, J.S.1
  • 36
    • 4344566310 scopus 로고    scopus 로고
    • Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse
    • Kapturczak,M.H. et al. (2004) Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am. J. Pathol., 165, 1045-1053.
    • (2004) Am. J. Pathol. , vol.165 , pp. 1045-1053
    • Kapturczak, M.H.1
  • 37
    • 0141707960 scopus 로고    scopus 로고
    • Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1
    • Morse,D. et al. (2003) Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J. Biol. Chem., 278, 36993-36998.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36993-36998
    • Morse, D.1
  • 38
    • 17644366432 scopus 로고    scopus 로고
    • Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity
    • Lad,L. et al. (2005) Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity. J. Biol. Inorg. Chem., 10, 138-146.
    • (2005) J. Biol. Inorg. Chem. , vol.10 , pp. 138-146
    • Lad, L.1
  • 39
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
    • Ryter,S.W. et al. (2006) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol. Rev., 86, 583-650.
    • (2006) Physiol. Rev. , vol.86 , pp. 583-650
    • Ryter, S.W.1
  • 40
    • 0034959256 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects against vascular constriction and proliferation
    • Duckers,H.J. et al. (2001) Heme oxygenase-1 protects against vascular constriction and proliferation. Nat. Med., 7, 693-698.
    • (2001) Nat. Med. , vol.7 , pp. 693-698
    • Duckers, H.J.1
  • 41
    • 0027458551 scopus 로고
    • Carbon monoxide: a putative neural messenger
    • Verma,A. et al. (1993) Carbon monoxide: a putative neural messenger. Science, 259, 381-384.
    • (1993) Science , vol.259 , pp. 381-384
    • Verma, A.1
  • 42
    • 0037124078 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis
    • Brouard,S. et al. (2002) Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis. J. Biol. Chem., 277, 17950-17961.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17950-17961
    • Brouard, S.1
  • 43
    • 0034054881 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts
    • Petrache,I. et al. (2000) Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts. Am. J. Physiol. Lung Cell. Mol. Physiol., 278, L312-L319.
    • (2000) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.278
    • Petrache, I.1
  • 44
    • 61649124114 scopus 로고    scopus 로고
    • Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress
    • De Backer,O. et al. (2009) Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress. Gut, 58, 347-356.
    • (2009) Gut , vol.58 , pp. 347-356
    • De Backer, O.1
  • 45
    • 0032870464 scopus 로고    scopus 로고
    • Cell motility mediated by rho and Rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma
    • Genda,T. et al. (1999) Cell motility mediated by rho and Rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma. Hepatology, 30, 1027-1036.
    • (1999) Hepatology , vol.30 , pp. 1027-1036
    • Genda, T.1


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