Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1β in osteoarthritic osteoblasts

Biochemical Pharmacology

Volumn 83, Issue 3, 2012, Pages 395-405

  Clérigues, Victoria ^a   Guillén, Maria Isabel ^a,b   Castejón, Miguel Angel ^c   Gomar, Francisco ^a   Mirabet, Vicente ^d   Alcaraz, Maria José ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^c De la Ribera University Hospital ^*  (Spain)

^d Valencia Transfusion Center   (Spain)

Author keywords

Cytokines; Heme oxygenase 1; Osteoarthritis; Osteoblasts; Senescence

Indexed keywords

BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN 2; CAVEOLIN 1; COLLAGEN TYPE 1; CYCLOOXYGENASE 2; GELATINASE A; HEME OXYGENASE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; OSTEOCALCIN; OSTEOPROTEGERIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTOPORPHYRIN COBALT; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; STROMELYSIN; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CARTILAGE DEGENERATION; CELL METABOLISM; CELL STIMULATION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; MALE; MINERALIZATION; OSTEOARTHRITIS; OSTEOBLAST; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

AGED; CELL AGING; CELLS, CULTURED; FEMALE; HEME OXYGENASE-1; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MALE; METABOLISM; MIDDLE AGED; OSTEITIS; OSTEOARTHRITIS; OSTEOBLASTS;

EID: 84455208060     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.11.024     Document Type: Article

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