메뉴 건너뛰기




Volumn 12, Issue 7, 2013, Pages 980-988

Suicide and the polyamine system

Author keywords

Epigenetics; Major depressive disorder; Neurobiology; Polyamine stress response; Polyamines; Spermidine spermine N1 acetyltransferase; Suicide

Indexed keywords

AGMATINE; ANTIZYME; CHOLINERGIC RECEPTOR; DEXAMETHASONE; IMIDAZOLINE RECEPTOR; LITHIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE; SEROTONIN RECEPTOR; SPERMIDINE; SPERMINE; SPERMINE SYNTHASE;

EID: 84889001629     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/18715273113129990095     Document Type: Review
Times cited : (26)

References (72)
  • 1
    • 12944273302 scopus 로고    scopus 로고
    • Psychiatric diagnoses in 3275 suicides: A meta-analysis
    • Arsenault-Lapierre, G.; Kim, C; Turecki, G. Psychiatric diagnoses in 3275 suicides: a meta-analysis. BMC Psychiatry, 2004, 4, 37.
    • (2004) BMC Psychiatry , vol.4 , pp. 37
    • Arsenault-Lapierre, G.1    Kim, C.2    Turecki, G.3
  • 7
    • 68049148368 scopus 로고    scopus 로고
    • Identification and characterization of spermidine/spermine Nl-acetyltransferase promoter variants in suicide completers
    • Fiori, L.M.; Mechawar, N.; Turecki, G. Identification and characterization of spermidine/spermine Nl-acetyltransferase promoter variants in suicide completers. Biol. Psychiatry, 2009, 66, 460-467.
    • (2009) Biol. Psychiatry , vol.66 , pp. 460-467
    • Fiori, L.M.1    Mechawar, N.2    Turecki, G.3
  • 8
    • 80051633382 scopus 로고    scopus 로고
    • Epigenetic regulation of spermidine/spermine N(l)-acetyltransferase (SAT1) in Suicide
    • Fiori, L.M.; Turecki, G. Epigenetic regulation of spermidine/spermine N(l)-acetyltransferase (SAT1) in Suicide. J. Psychiatric Res., 2011, 45, 1229-1235.
    • (2011) J. Psychiatric Res , vol.45 , pp. 1229-1235
    • Fiori, L.M.1    Turecki, G.2
  • 10
    • 34047241993 scopus 로고    scopus 로고
    • Penafiel R Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: Influence of polyamine deprivation on catecholamine and corticoid levels
    • Bastida, CM.; Cremades, A.; Castells, M.T.; Lopez-Contreras, A.J.; Lopez-Garcia, C; Sanchez-Mas J, Penafiel R Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels. Am. J. Physiol. Endocrinol. Metab., 2007, 292, E1010-E1017.
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.292
    • Bastida, C.M.1    Cremades, A.2    Castells, M.T.3    Lopez-Contreras, A.J.4    Lopez-Garcia, C.5    Sanchez-Mas, J.6
  • 11
    • 0028302022 scopus 로고
    • Spermine interacts with cocaine binding sites on dopamine transporters
    • Ritz, M.C.; Mantione, C.R.; London, E.D. Spermine interacts with cocaine binding sites on dopamine transporters. Psychopharmacology, 1994, 114, 47-52.
    • (1994) Psychopharmacology , vol.114 , pp. 47-52
    • Ritz, M.C.1    Mantione, C.R.2    London, E.D.3
  • 12
    • 0026649251 scopus 로고
    • Polyamines modulate the binding of GABAA-benzodiazepine receptor ligands in membranes from the rat forebrain
    • Gilad, G; Gilad, V.H.; Wyatt, RJ. Polyamines modulate the binding of GABAA-benzodiazepine receptor ligands in membranes from the rat forebrain. Neuropharmacology, 1992, 31, 895-898.
    • (1992) Neuropharmacology , vol.31 , pp. 895-898
    • Gilad, G.1    Gilad, V.H.2    Wyatt, R.J.3
  • 13
    • 40549089913 scopus 로고    scopus 로고
    • Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation
    • de Vera, N.; Martinez, E.; Sanfeliu, C. Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation. J. Neurosci. Res., 2008, 86, 861-872.
    • (2008) J. Neurosci. Res , vol.86 , pp. 861-872
    • de Vera, N.1    Martinez, E.2    Sanfeliu, C.3
  • 14
    • 0029941131 scopus 로고    scopus 로고
    • Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine
    • Galea, E.; Regunathan, S.; Eliopoulos, V.; Feinstein, D.L.; Reis, D.J. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine. Biochem. J., 1996, 316(Pt 1), 247-249.
    • (1996) Biochem. J , vol.316 , Issue.PART 1 , pp. 247-249
    • Galea, E.1    Regunathan, S.2    Eliopoulos, V.3    Feinstein, D.L.4    Reis, D.J.5
  • 15
    • 0034193104 scopus 로고    scopus 로고
    • Is agmatine a novel neurotransmitter in brain?
    • Reis, D.J.; Regunathan, S. Is agmatine a novel neurotransmitter in brain? Trends Pharmacol. Sci., 2000, 21, 187-193.
    • (2000) Trends Pharmacol. Sci , vol.21 , pp. 187-193
    • Reis, D.J.1    Regunathan, S.2
  • 16
    • 0030899291 scopus 로고    scopus 로고
    • Modulation and block of ion channels: A new biology of polyamines
    • Williams, K. Modulation and block of ion channels: a new biology of polyamines. Cell. Signal., 1997, 9, 1-13.
    • (1997) Cell. Signal , vol.9 , pp. 1-13
    • Williams, K.1
  • 17
    • 33644942525 scopus 로고    scopus 로고
    • Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment
    • Krauss, M.; Langnaese, K.; Richter, K.; Brunk, I.; Wieske, M.; Ahnert-Hilger, G.; Veh, RW.; Laube, G. Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment. J. Neurochem., 2006, 97, 174-189.
    • (2006) J. Neurochem , vol.97 , pp. 174-189
    • Krauss, M.1    Langnaese, K.2    Richter, K.3    Brunk, I.4    Wieske, M.5    Ahnert-Hilger, G.6    Veh, R.W.7    Laube, G.8
  • 18
    • 0032536718 scopus 로고    scopus 로고
    • Regional localization of agmatine in the rat brain: An immunocytochemical study
    • Otake, K.; Ruggiero, D.A.; Regunathan, S.; Wang, H.; Milner, T.A; Reis, D.J. Regional localization of agmatine in the rat brain: an immunocytochemical study. Brain Res., 1998, 787, 1-14.
    • (1998) Brain Res , vol.787 , pp. 1-14
    • Otake, K.1    Ruggiero, D.A.2    Regunathan, S.3    Wang, H.4    Milner, T.A.5    Reis, D.J.6
  • 19
    • 0036316416 scopus 로고    scopus 로고
    • Passage of spermidine across the blood-brain barrier in short recirculation periods following global cerebral ischemia: Effects of mild hyperthermia
    • Diler, AS.; Ziylan, Y.Z.; Uzum, G; Lefauconnier, J.M.; Seylaz, I; Pinard, E. Passage of spermidine across the blood-brain barrier in short recirculation periods following global cerebral ischemia: effects of mild hyperthermia. Neurosci. Res., 2002, 43, 335-342.
    • (2002) Neurosci. Res , vol.43 , pp. 335-342
    • Diler, A.S.1    Ziylan, Y.Z.2    Uzum, G.3    Lefauconnier, J.M.4    Seylaz, I.5    Pinard, E.6
  • 20
    • 0019831608 scopus 로고
    • Polyamine metabolism and function in brain
    • Seiler, N. Polyamine metabolism and function in brain. Neurochem. Intl., 1981, 3, 95-110.
    • (1981) Neurochem. Intl , vol.3 , pp. 95-110
    • Seiler, N.1
  • 22
    • 0036787990 scopus 로고    scopus 로고
    • Agmatine suppresses nitric oxide production and attenuates hypoxic-ischemic brain injury in neonatal rats
    • Feng, Y.; Piletz, J.E.; Leblanc, M.H. Agmatine suppresses nitric oxide production and attenuates hypoxic-ischemic brain injury in neonatal rats. Pediat. Res., 2002, 52, 606-611.
    • (2002) Pediat. Res , vol.52 , pp. 606-611
    • Feng, Y.1    Piletz, J.E.2    Leblanc, M.H.3
  • 23
    • 55349134543 scopus 로고    scopus 로고
    • Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model
    • Luszczki, J.J.; Czernecki, R; Wojtal, K.; Borowicz, K.K.; Czuczwar, S.J. Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model. J. Neural Transm., 2008, 115, 1485-1494.
    • J. Neural Transm., 2008 , vol.115 , pp. 1485-1494
    • Luszczki, J.J.1    Czernecki, R.2    Wojtal, K.3    Borowicz, K.K.4    Czuczwar, S.J.5
  • 24
    • 0037064234 scopus 로고    scopus 로고
    • Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil
    • Gibson, D.A; Harris, B.R.; Rogers, D.T.; Littleton, J.M. Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil. Brain research 2002, 952, 71-77.
    • (2002) Brain Research , vol.952 , pp. 71-77
    • Gibson, D.A.1    Harris, B.R.2    Rogers, D.T.3    Littleton, J.M.4
  • 25
    • 0038392436 scopus 로고    scopus 로고
    • Antidepressant-like effect of agmatine and its possible mechanism
    • Li, Y.F.; Gong, Z.H.; Cao, IB.; Wang, H.L.; Luo, Z.P.; Li, J. Antidepressant-like effect of agmatine and its possible mechanism. Eur. J. Pharmacol, 2003, 469, 81-88.
    • (2003) Eur. J. Pharmacol , vol.469 , pp. 81-88
    • Li, Y.F.1    Gong, Z.H.2    Cao, I.B.3    Wang, H.L.4    Luo, Z.P.5    Li, J.6
  • 27
    • 68749114959 scopus 로고    scopus 로고
    • Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine
    • Taksande, B.G; Kotagale, N.R; Tripathi, S.J.; Ugale, RR; Chopde, C.T. Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine. Neuropharmacology, 2009, 57, 415-424.
    • (2009) Neuropharmacology , vol.57 , pp. 415-424
    • Taksande, B.G.1    Kotagale, N.R.2    Tripathi, S.J.3    Ugale, R.R.4    Chopde, C.T.5
  • 28
    • 0035930459 scopus 로고    scopus 로고
    • Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression
    • Genedani, S.; Saltini, S.; Benelli, A.; Filaferro, M.; Bertolini, A. Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression. Neuroreport, 2001, 12, 3939-3942.
    • (2001) Neuroreport , vol.12 , pp. 3939-3942
    • Genedani, S.1    Saltini, S.2    Benelli, A.3    Filaferro, M.4    Bertolini, A.5
  • 29
    • 33750352828 scopus 로고    scopus 로고
    • Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice
    • Zomkowski, A.D.; Santos, A.R.; Rodrigues, AL. Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2006, 30, 1419-1425.
    • (2006) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.30 , pp. 1419-1425
    • Zomkowski, A.D.1    Santos, A.R.2    Rodrigues, A.L.3
  • 35
    • 80053133170 scopus 로고    scopus 로고
    • Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA
    • Kurian, L.; Palanimurugan, R.; Godderz, D.; Dohmen, R.J. Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA. Nature, 2011, 477, 490-494.
    • (2011) Nature , vol.477 , pp. 490-494
    • Kurian, L.1    Palanimurugan, R.2    Godderz, D.3    Dohmen, R.J.4
  • 36
    • 11244337377 scopus 로고    scopus 로고
    • Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme
    • Palanimurugan, R.; Scheel, H.; Hofmann, K.; Dohmen, RJ. Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme. EMBO J., 2004, 23, 4857-4867.
    • (2004) EMBO J , vol.23 , pp. 4857-4867
    • Palanimurugan, R.1    Scheel, H.2    Hofmann, K.3    Dohmen, R.J.4
  • 37
    • 77955360283 scopus 로고    scopus 로고
    • S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: A double-blind, randomized clinical trial
    • Papakostas, G.I.; Mischoulon, D.; Shyu, I.; Alpert, J.E.; Fava, M. S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. Am. J. Psychiatry, 2010, 767, 942-948.
    • (2010) Am. J. Psychiatry , vol.7 , Issue.67 , pp. 942-948
    • Papakostas, G.I.1    Mischoulon, D.2    Shyu, I.3    Alpert, J.E.4    Fava, M.5
  • 38
    • 41149114638 scopus 로고    scopus 로고
    • Implication of the polyamine system in mental disorders
    • Fiori, L.M.; Turecki, G. Implication of the polyamine system in mental disorders. J. Psychiatry Neurosci. JPN, 2008, 33, 102-110.
    • (2008) J. Psychiatry Neurosci. JPN , vol.33 , pp. 102-110
    • Fiori, L.M.1    Turecki, G.2
  • 41
    • 29144471872 scopus 로고    scopus 로고
    • Dissecting the suicide phenotype: The role of impulsive-aggressive behaviours
    • Turecki, G. Dissecting the suicide phenotype: the role of impulsive-aggressive behaviours. J. Psychiatry Neurosci. JPN, 2005, 30, 398-408.
    • (2005) J. Psychiatry Neurosci. JPN , vol.30 , pp. 398-408
    • Turecki, G.1
  • 42
    • 0031938688 scopus 로고    scopus 로고
    • Nitric oxide, free radicals and polyamines may have a role in the membrane pathology of schizophrenia
    • Das, I.; Ramchand, C.N.; Gliddon, A.; Hirsch, S.R. Nitric oxide, free radicals and polyamines may have a role in the membrane pathology of schizophrenia. Neuropsychobiology, 1998, 37, 65-67.
    • (1998) Neuropsychobiology , vol.37 , pp. 65-67
    • Das, I.1    Ramchand, C.N.2    Gliddon, A.3    Hirsch, S.R.4
  • 43
    • 0029162119 scopus 로고
    • Polyamines and their metabolizing enzymes in human frontal cortex and hippocampus: Preliminary measurements in affective disorders
    • Gilad, G.M.; Gilad, V.H.; Casanova, M.F.; Casero, R.A., Jr. Polyamines and their metabolizing enzymes in human frontal cortex and hippocampus: preliminary measurements in affective disorders. Biol. Psychiatry, 1995, 38, 227-234.
    • (1995) Biol. Psychiatry , vol.38 , pp. 227-234
    • Gilad, G.M.1    Gilad, V.H.2    Casanova, M.F.3    Casero Jr., R.A.4
  • 44
    • 0026741533 scopus 로고
    • Polyamines in neurotrauma. Ubiquitous molecules in search of a function
    • Gilad, G.M.; Gilad, V.H. Polyamines in neurotrauma. Ubiquitous molecules in search of a function. Biochem. Pharmacol, 1992, 44, 401-407.
    • (1992) Biochem. Pharmacol , vol.44 , pp. 401-407
    • Gilad, G.M.1    Gilad, V.H.2
  • 45
    • 0041315749 scopus 로고    scopus 로고
    • Overview of the brain polyamine-stress-response: Regulation, development, and modulation by lithium and role in cell survival
    • Gilad, G.M.; Gilad, V.H. Overview of the brain polyamine-stress-response: regulation, development, and modulation by lithium and role in cell survival. Cell. Mol Neurobiol, 2003, 23, 637-649.
    • (2003) Cell. Mol Neurobiol , vol.23 , pp. 637-649
    • Gilad, G.M.1    Gilad, V.H.2
  • 46
    • 0026514730 scopus 로고
    • Chronic lithium treatment prevents the dexamethasone-induced increase of brain polyamine metabolizing enzymes
    • Gilad, G.M.; Gilad, V.H.; Wyatt, R.J.; Casero, R.A., Jr. Chronic lithium treatment prevents the dexamethasone-induced increase of brain polyamine metabolizing enzymes. Life Sci., 1992, 50, PL149-154.
    • (1992) Life Sci , vol.50 , pp. 49-154
    • Gilad, G.M.1    Gilad, V.H.2    Wyatt, R.J.3    Casero, R.A.4
  • 47
    • 0028158231 scopus 로고
    • Lithium exerts a time-dependent and tissue-selective attenuation of the dexamethasone-induced polyamine response in rat brain and liver
    • Gilad, G.M.; Gilad, V.H.; Casero, R.A., Jr. Lithium exerts a time-dependent and tissue-selective attenuation of the dexamethasone-induced polyamine response in rat brain and liver. Brain Res., 1994, 636, 187-192.
    • (1994) Brain Res , vol.636 , pp. 187-192
    • Gilad, G.M.1    Gilad, V.H.2    Casero Jr., R.A.3
  • 48
    • 0035310470 scopus 로고    scopus 로고
    • Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine Nl-acetyltransferase (SSAT) gene
    • Wang, Y.; Devereux, W.; Stewart, T.M.; Casero, R.A., Jr. Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine Nl-acetyltransferase (SSAT) gene. Biochem. J., 2001, 355, 45-49.
    • (2001) Biochem. J , vol.355 , pp. 45-49
    • Wang, Y.1    Devereux, W.2    Stewart, T.M.3    Casero Jr., R.A.4
  • 49
    • 34548701403 scopus 로고    scopus 로고
    • Polyamine-modulated factor 1 represses glucocorticoid receptor activity
    • Shoji, Y.; Osman, W.; Zilliacus, J. Polyamine-modulated factor 1 represses glucocorticoid receptor activity. Biochem. Biophys. Res. Commun., 2007, 361, 176-181.
    • (2007) Biochem. Biophys. Res. Commun , vol.361 , pp. 176-181
    • Shoji, Y.1    Osman, W.2    Zilliacus, J.3
  • 51
    • 84862027231 scopus 로고    scopus 로고
    • Differential glucocorticoid receptor exon 7(B), 7(C), and 7(H) expression and methylation in suicide completers with a history of childhood abuse
    • Labonte, B.; Yerko, V.; Gross, J; Mechawar, N.; Meaney, M.J.; Szyf, M.; Turecki, G. Differential glucocorticoid receptor exon 7(B), 7(C), and 7(H) expression and methylation in suicide completers with a history of childhood abuse. Biol. Psychiatry, 2012, 72, 41-48.
    • (2012) Biol. Psychiatry , vol.72 , pp. 41-48
    • Labonte, B.1    Yerko, V.2    Gross, J.3    Mechawar, N.4    Meaney, M.J.5    Szyf, M.6    Turecki, G.7
  • 52
    • 84884289587 scopus 로고    scopus 로고
    • Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: Associations and gene-environment interactions with childhood/adolescent physical assault
    • [Epub ahead of print]
    • Sokolowski, M.; Ben-Efraim, Y.J.; Wasserman, J.; Wasserman, D. Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene-environment interactions with childhood/adolescent physical assault. Mol Psychiatry, 2012 [Epub ahead of print].
    • (2012) Mol Psychiatry
    • Sokolowski, M.1    Ben-Efraim, Y.J.2    Wasserman, J.3    Wasserman, D.4
  • 53
    • 9444249291 scopus 로고    scopus 로고
    • Spermidine/spermine-Nl-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism
    • Coleman, C.S.; Stanley, B.A.; Jones, A.D.; Pegg, A.E. Spermidine/spermine-Nl-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism. Biochem. J., 2004, 384, 139-148.
    • (2004) Biochem. J , vol.384 , pp. 139-148
    • Coleman, C.S.1    Stanley, B.A.2    Jones, A.D.3    Pegg, A.E.4
  • 55
    • 77957170637 scopus 로고    scopus 로고
    • Turecki, G Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers
    • Fiori, L.M.; Turecki, G Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers. Ml J. Neuropsychopharmacol, 2010, 13, 725-736.
    • (2010) Ml J. Neuropsychopharmacol , vol.13 , pp. 725-736
    • Fiori, L.M.1
  • 56
    • 84864571573 scopus 로고    scopus 로고
    • Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide
    • Fiori, L.M.; Gross, J.A.; Turecki, G Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide. Ml J. Neuropsychopharmacol., 2012, 75(8), 1161-1166.
    • (2012) Ml J. Neuropsychopharmacol , vol.75 , Issue.8 , pp. 1161-1166
    • Fiori, L.M.1    Gross, J.A.2    Turecki, G.3
  • 57
    • 70349131615 scopus 로고    scopus 로고
    • A quantitative GC-MS method for three major polyamines in postmortem brain cortex
    • Chen, G.G.; Turecki, G; Mamer, O.A. A quantitative GC-MS method for three major polyamines in postmortem brain cortex. J. Mass Spectromet, 2009, 44, 1203-1210.
    • (2009) J. Mass Spectromet , vol.44 , pp. 1203-1210
    • Chen, G.G.1    Turecki, G.2    Mamer, O.A.3
  • 58
    • 77951748571 scopus 로고    scopus 로고
    • A novel liquid-liquid extraction and stable isotope dilution NCI-GC-MS method for quantitation of agmatine in postmortem brain cortex
    • Chen, GG; Turecki, G.; Mamer, O.A. A novel liquid-liquid extraction and stable isotope dilution NCI-GC-MS method for quantitation of agmatine in postmortem brain cortex. J. Mass Spectromet., 2010, 45, 560-565.
    • (2010) J. Mass Spectromet , vol.45 , pp. 560-565
    • Chen, G.G.1    Turecki, G.2    Mamer, O.A.3
  • 59
    • 79956189529 scopus 로고    scopus 로고
    • Turecki, G High-resolution capillary gas chromatography in combination with mass speclrometry for quantification of three major polyamines in postmortem brain cortex
    • Chen, G.G.; Fiori, L.M.; Mamer, O.A.; Turecki, G High-resolution capillary gas chromatography in combination with mass speclrometry for quantification of three major polyamines in postmortem brain cortex. Methods Mol Biol, 2011, 720, 427-436.
    • (2011) Methods Mol Biol , vol.720 , pp. 427-436
    • Chen, G.G.1    Fiori, L.M.2    Mamer, O.A.3
  • 64
    • 70450176287 scopus 로고    scopus 로고
    • Epigenomics: Methylation matters
    • Schubeler, D. Epigenomics: Methylation matters. Nature, 2009, 462, 296-297.
    • (2009) Nature , vol.462 , pp. 296-297
    • Schubeler, D.1
  • 65
    • 78049274861 scopus 로고    scopus 로고
    • Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice
    • Elliott, E.; Ezra-Nevo, G; Regev, L.; Neufeld-Cohen, A.; Chen, A. Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat. Neurosci., 2010, 13, 1351-1353.
    • (2010) Nat. Neurosci , vol.13 , pp. 1351-1353
    • Elliott, E.1    Ezra-Nevo, G.2    Regev, L.3    Neufeld-Cohen, A.4    Chen, A.5
  • 67
    • 80054739563 scopus 로고    scopus 로고
    • The hunt for 5-hydroxymethylcytosine: The sixth base
    • Song, C.X.; He, C. The hunt for 5-hydroxymethylcytosine: the sixth base. Epigenomics, 2011, 3, 521-523.
    • (2011) Epigenomics , vol.3 , pp. 521-523
    • Song, C.X.1    He, C.2
  • 69
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis, S.; Heintz, N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 2009, 324, 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 70
    • 84864129535 scopus 로고    scopus 로고
    • Distribution of 5-hydroxymethylcytosine in different human tissues
    • Li, W.; Liu, M. Distribution of 5-hydroxymethylcytosine in different human tissues. J. Nucleic Acids, 2011, 2011, 870726.
    • (2011) J. Nucleic Acids , vol.2011 , pp. 870726
    • Li, W.1    Liu, M.2
  • 71
    • 79960249232 scopus 로고    scopus 로고
    • Genomic mapping of 5-hydroxymethylcytosine in the human brain
    • Jin, S.G.; Wu, X.; Li, A.X.; Pfeifer, G.P. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res., 2011, 39, 5015-5024.
    • (2011) Nucleic Acids Res , vol.39 , pp. 5015-5024
    • Jin, S.G.1    Wu, X.2    Li, A.X.3    Pfeifer, G.P.4
  • 72
    • 79960117245 scopus 로고    scopus 로고
    • Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress
    • Chia, N.; Wang, L.; Lu, X.; Senut, M.C.; Brenner, C; Ruden, D.M. Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress. Epigenetics, 2011, 6, 853-856.
    • (2011) Epigenetics , vol.6 , pp. 853-856
    • Chia, N.1    Wang, L.2    Lu, X.3    Senut, M.C.4    Brenner, C.5    Ruden, D.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.