Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA

Nature

Volumn 477, Issue 7365, 2011, Pages 490-494

  Kurian, Leo ^a,b   Palanimurugan, R ^a   Gödderz, Daniela ^a,c   Dohmen, R Jürgen ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIZYME; MALTOSE BINDING PROTEIN; MESSENGER RNA; POLYAMINE; PROTEASOME; SPERMIDINE;

ENZYME ACTIVITY; GENE EXPRESSION; MOLECULAR ANALYSIS; PEPTIDE; RNA; YEAST;

ARTICLE; CODON; ENZYME SYNTHESIS; GENE DECODING; GENE MUTATION; HUMAN; MOLECULAR GENETICS; NONHUMAN; OPEN READING FRAME; POLYSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RIBOSOMAL FRAMESHIFTING; SACCHAROMYCES CEREVISIAE; SENSOR;

AMINO ACID SEQUENCE; BASE SEQUENCE; FRAMESHIFTING, RIBOSOMAL; MOLECULAR SEQUENCE DATA; ORNITHINE DECARBOXYLASE; POLYAMINES; PROTEINS; RIBOSOMES; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; UBIQUITIN;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 80053133170     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10393     Document Type: Article

References (22)

1. Coffino, P. Regulation of cellular polyamines by antizyme.Nature Rev.Mol. Cell Biol. 2, 188-194 (2001). (Pubitemid 33675743)
2. Wallace, H. M., Fraser, A. V. & Hughes, A. A perspective of polyamine metabolism. Biochem. J. 376, 1-14 (2003). (Pubitemid 37487199)
3. Eisenberg, T., et al. Induction of autophagy by spermidine promotes longevity. Nature Cell Biol. 11, 1305-1314 (2009).
4. Hayashi, S., Murakami, Y. & Matsufuji, S. Ornithine decarboxylase antizyme: a novel type of regulatory protein. Trends Biochem. Sci. 21, 27-30 (1996). (Pubitemid 26032305)
5. Murakami, Y., et al. Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. Nature 360, 597-599 (1992). (Pubitemid 23000711)
6. Ivanov, I. P. & Atkins, J. F. Ribosomal frameshifting in decoding antizyme mRNAs fromyeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation. Nucleic Acids Res. 35, 1842-1858 (2007). (Pubitemid 47064260)
7. Palanimurugan, R., Scheel, H., Hofmann, K. & Dohmen, R. J. Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme. EMBO J. 23, 4857-4867 (2004). (Pubitemid 40069715)
8. Matsufuji, S., et al. Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Cell 80, 51-60 (1995).
9. Rom, E. & Kahana, C. Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting. Proc. Natl Acad. Sci. USA 91, 3959-3963 (1994); erratum 91, 9195 (1994). (Pubitemid 24139552)
10. Rato, C., Amirova, S. R., Bates, D. G., Stansfield, I. & Wallace, H. M. Translational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshift. Nucleic Acids Res. 39, 4587-4597 (2011).
11. Heinemeyer, W., Kleinschmidt, J. A., Saidowsky, J., Escher, C. & Wolf, D. H. Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival. EMBO J. 10, 555-562 (1991). (Pubitemid 21905508)
12. Tenson, T. & Ehrenberg, M. Regulatory nascent peptides in the ribosomal tunnel. Cell 108, 591-594 (2002). (Pubitemid 34241420)
13. Inada, T., et al. One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs. RNA 8, 948-958 (2002). (Pubitemid 34787691)
14. Arava, Y., Boas, F. E., Brown, P. O. & Herschlag, D. Dissecting eukaryotic translation and its control by ribosome density mapping. Nucleic Acids Res. 33, 2421-2432 (2005). (Pubitemid 41511261)
15. Baim, S. B. & Sherman, F. mRNA structures influencing translation in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 8, 1591-1601 (1988).
16. Hoffman, D. W., Carroll, D., Martinez, N. & Hackert, M. L. Solution structure of a conserved domain of antizyme: a protein regulator of polyamines. Biochemistry 44, 11777-11785 (2005). (Pubitemid 41262712)
17. Nakatogawa, H. & Ito, K. The ribosomal exit tunnel functions as a discriminating gate. Cell 108, 629-636 (2002). (Pubitemid 34241424)
18. Woolhead, C. A., Johnson, A. E. & Bernstein, H. D. Translation arrest requires twoway communication between a nascent polypeptide and the ribosome. Mol. Cell 22, 587-598 (2006). (Pubitemid 43817608)
19. Butcher, N. J., Broadhurst, G. M. & Minchin, R. F. Polyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation. J. Biol. Chem. 282, 28530-28539 (2007). (Pubitemid 47606010)
20. Basuroy, U. K. & Gerner, E. W. Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy. J. Biochem. 139, 27-33 (2006). (Pubitemid 43258843)
21. Lim, S. K. & Gopalan, G. Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A. Oncogene 26, 6593-6603 (2007). (Pubitemid 47573681)
22. Dulloo, I., Gopalan, G., Melino, G. & Sabapathy, K. The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc. Natl Acad. Sci. USA 107, 4902-4907 (2010).